DK0902783T3 - Hydrolysefremmende, hydrofobe taxanderivater - Google Patents

Hydrolysefremmende, hydrofobe taxanderivater

Info

Publication number
DK0902783T3
DK0902783T3 DK96930847T DK96930847T DK0902783T3 DK 0902783 T3 DK0902783 T3 DK 0902783T3 DK 96930847 T DK96930847 T DK 96930847T DK 96930847 T DK96930847 T DK 96930847T DK 0902783 T3 DK0902783 T3 DK 0902783T3
Authority
DK
Denmark
Prior art keywords
hydrolysis
taxane
hydrocarbon
promoting
taxane derivatives
Prior art date
Application number
DK96930847T
Other languages
English (en)
Inventor
Eric Mayhew
Shaukat Ali
Andrew S Janoff
Original Assignee
Liposome Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Liposome Co Inc filed Critical Liposome Co Inc
Application granted granted Critical
Publication of DK0902783T3 publication Critical patent/DK0902783T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Medicinal Preparation (AREA)
DK96930847T 1995-09-12 1996-09-12 Hydrolysefremmende, hydrofobe taxanderivater DK0902783T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US357595P 1995-09-12 1995-09-12
PCT/US1996/014631 WO1997010234A1 (en) 1995-09-12 1996-09-12 Hydrolysis-promoting taxane hydrophobic derivatives

Publications (1)

Publication Number Publication Date
DK0902783T3 true DK0902783T3 (da) 2002-07-22

Family

ID=21706522

Family Applications (2)

Application Number Title Priority Date Filing Date
DK96930847T DK0902783T3 (da) 1995-09-12 1996-09-12 Hydrolysefremmende, hydrofobe taxanderivater
DK02008590T DK1229030T3 (da) 1995-09-12 1996-09-12 Hydrolysefremmende, hydrofobe taxanderivater

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK02008590T DK1229030T3 (da) 1995-09-12 1996-09-12 Hydrolysefremmende, hydrofobe taxanderivater

Country Status (22)

Country Link
US (1) US5703117A (da)
EP (1) EP0902783B1 (da)
JP (1) JP4192208B2 (da)
KR (1) KR100401220B1 (da)
CN (1) CN1100770C (da)
AT (2) ATE309235T1 (da)
CA (1) CA2231750C (da)
CZ (1) CZ288562B6 (da)
DE (2) DE69620802T2 (da)
DK (2) DK0902783T3 (da)
ES (2) ES2252347T3 (da)
HK (1) HK1016169A1 (da)
HU (1) HU226325B1 (da)
IL (1) IL123595A (da)
MX (1) MX9801871A (da)
NO (1) NO319521B1 (da)
NZ (1) NZ318300A (da)
PL (1) PL187738B1 (da)
PT (1) PT902783E (da)
SK (1) SK283199B6 (da)
TR (1) TR199800443T1 (da)
WO (1) WO1997010234A1 (da)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6107332A (en) * 1995-09-12 2000-08-22 The Liposome Company, Inc. Hydrolysis-promoting hydrophobic taxane derivatives
US6667053B1 (en) * 1996-02-16 2003-12-23 Elan Pharmaceuticals, Inc. D and L etherlipid stereoisomers and liposomes
US5912264A (en) * 1997-03-03 1999-06-15 Bristol-Myers Squibb Company 6-halo-or nitrate-substituted paclitaxels
US8853260B2 (en) 1997-06-27 2014-10-07 Abraxis Bioscience, Llc Formulations of pharmacological agents, methods for the preparation thereof and methods for the use thereof
ID25622A (id) 1997-11-10 2000-10-19 Sloan Kettering Inst Cancer Proses untuk memproduksi formulasi arsenat trioksida dan metoda untuk mengobati kanker dengan menggunakan arsenat trioksida atau melarsoprol
PL344327A1 (en) * 1998-05-20 2001-10-22 Liposome Co Inc Novel particulate formulations
US6146659A (en) * 1998-07-01 2000-11-14 Neopharm, Inc. Method of administering liposomal encapsulated taxane
US7314637B1 (en) 1999-06-29 2008-01-01 Neopharm, Inc. Method of administering liposomal encapsulated taxane
CA2358638A1 (en) * 1999-01-12 2000-07-20 Quanam Medical Corporation Composition and methods for administration of water-insoluble paclitaxel derivatives
EP2289549A3 (en) 1999-10-01 2011-06-15 Immunogen, Inc. Immunoconjugates for treating cancer
JP2004501143A (ja) 2000-06-22 2004-01-15 ニトロメド　インコーポレーテッド ニトロソ化およびニトロシル化タキサン、組成物および使用方法
US6607689B1 (en) * 2000-08-29 2003-08-19 Micron Technology, Inc. Layer thickness control for stereolithography utilizing variable liquid elevation and laser focal length
DE60137229D1 (de) * 2001-10-22 2009-02-12 Viroblock Sa Non-phospholipid Vesikel (npLV) und ihre Verwendung in kosmetischen, therapeutischen und prophylaktischen Anwendungen
AU2002351169B2 (en) * 2001-11-26 2007-09-20 Intas Pharmaceuticals Limited Method for preparing and using polyoxyethylated castor oil in pharmaceutical compositions
DE60335279D1 (de) * 2002-06-26 2011-01-20 Medigene Ag Neues verfahren zur stabilisierung von diagnostischen und therapeutischen verbindungen in einem kationischen trägersystem
WO2004069224A2 (en) 2003-02-03 2004-08-19 Neopharm, Inc. Stable sterile filterable liposomal encapsulated taxane and other antineoplastic drugs
EP3345632A1 (en) * 2005-02-18 2018-07-11 Abraxis BioScience, LLC Drugs with improved hydrophobicity for incorporation in medical devices
AU2006235538A1 (en) 2005-04-12 2006-10-19 Wisconsin Alumni Research Foundation Micelle composition of polymer and passenger drug
WO2009126401A1 (en) * 2008-04-10 2009-10-15 Abraxis Bioscience, Llc Compositions of hydrophobic taxane derivatives and uses thereof
KR20100133475A (ko) * 2008-04-10 2010-12-21 아브락시스 바이오사이언스, 엘엘씨 소수성 탁산 유도체의 조성물 그의 용도
EP2480207B1 (en) 2009-09-25 2016-11-09 Wisconsin Alumni Research Foundation Micelle encapsulation of therapeutic agents
CN105503844A (zh) * 2015-12-11 2016-04-20 上海大学 C-13和c-7位结构改造的紫杉醇类化合物及其制备方法
CN111004195B (zh) * 2019-12-03 2022-01-28 沈阳药科大学 卡巴他赛弱碱性衍生物及其制剂

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5278324A (en) * 1990-08-28 1994-01-11 Virginia Tech Intellectual Properties, Inc. Water soluble derivatives of taxol
US5059699A (en) * 1990-08-28 1991-10-22 Virginia Tech Intellectual Properties, Inc. Water soluble derivatives of taxol
CZ292993B6 (cs) * 1992-12-23 2004-01-14 Bristol-Myers Squibb Company Způsob přípravy taxanu nesoucího oxazolinový postranní řetězec a taxan tímto způsobem připravený
IL108316A (en) * 1993-01-15 2006-10-31 Univ Florida State History of C-10 Texan and pharmaceuticals containing them
US5580899A (en) * 1995-01-09 1996-12-03 The Liposome Company, Inc. Hydrophobic taxane derivatives

Also Published As

Publication number Publication date
US5703117A (en) 1997-12-30
PL187738B1 (pl) 2004-09-30
NO981071D0 (no) 1998-03-11
NO981071L (no) 1998-05-12
HU226325B1 (en) 2008-08-28
CZ71198A3 (cs) 1998-07-15
DE69635428T2 (de) 2006-06-14
MX9801871A (es) 1998-05-31
ATE309235T1 (de) 2005-11-15
ATE216377T1 (de) 2002-05-15
CA2231750A1 (en) 1997-03-20
NO319521B1 (no) 2005-08-22
CN1100770C (zh) 2003-02-05
IL123595A0 (en) 1998-10-30
KR100401220B1 (ko) 2004-03-20
HUP9901433A2 (hu) 2001-04-28
ES2179208T3 (es) 2003-01-16
DE69620802D1 (de) 2002-05-23
DE69635428D1 (de) 2005-12-15
CA2231750C (en) 2006-07-11
EP0902783A4 (da) 1999-03-24
HUP9901433A3 (en) 2001-05-28
AU706290B2 (en) 1999-06-10
SK33498A3 (en) 1998-08-05
HK1016169A1 (en) 1999-10-29
DK1229030T3 (da) 2006-02-13
SK283199B6 (sk) 2003-03-04
JP2001519755A (ja) 2001-10-23
EP0902783B1 (en) 2002-04-17
TR199800443T1 (xx) 1998-06-22
DE69620802T2 (de) 2002-10-10
PL325477A1 (en) 1998-07-20
CZ288562B6 (cs) 2001-07-11
PT902783E (pt) 2002-09-30
IL123595A (en) 2000-10-31
ES2252347T3 (es) 2006-05-16
EP0902783A1 (en) 1999-03-24
WO1997010234A1 (en) 1997-03-20
AU6975696A (en) 1997-04-01
JP4192208B2 (ja) 2008-12-10
NZ318300A (en) 1999-08-30
CN1202166A (zh) 1998-12-16
KR19990044409A (ko) 1999-06-25

Similar Documents

Publication Publication Date Title
DK1229030T3 (da) Hydrolysefremmende, hydrofobe taxanderivater
ATE219363T1 (de) Lösliche prodrugs von paclitaxel
EA200000282A1 (ru) Способ введения таксана пациенту, нуждающемуся в лечении таксаном, способ лечения человека таксаном (варианты)
PT802911E (pt) Derivados de taxano hidrofobos
DE69226197D1 (de) Hämoglobine als arzneimittelabgabesystem
TR200102603T2 (tr) Antitümör aktiviteye sahip olan kamptotesin türevleri
PT977564E (pt) Forscolina para promocao da massa corporal magra
ATE433959T1 (de) Analoge von kokain
NL970006I1 (nl) Gebruik van indolon-derivaten voor het bereiden van geneesmiddelen ter behandeling van de ziekte vanParkinson.
CY1109695T1 (el) Μικροοργανισμοι αποδομησης οξαλικου ή ενζυμα αποδομησης οξαλικου για την προληψη παθησης σχετιζομενης με οξαλικο
NO172344C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive substituerte flavonoidforbindelser og salter
DE69631975D1 (de) Discodermolide verbindungen und deren pharmazeutische zusammensetzungen zur krebstherapie
SE8404283D0 (sv) Anvendning av ett specifikt tumorassocierat antigen, nemligen sialosyllaktotetraos, for diagnostiska och terapeutiska forfaranden vid cancersjukdomar
ES2038642T3 (es) Tratamiento dermico de enfermedades vermiculares del gato con pracicuantel.
ATE141796T1 (de) 2',5'-oligoadenylat-derivate zur verwendung als heilmittel
EP1229030A3 (en) Hydrolysis-promoting taxane hydrophobic derivates
ES8605989A1 (es) Un metodo de preparar un complejo de fibronectina, dextrano y farmaco
RU94018405A (ru) Устройство для воздействия магнитным полем
IT8620514V0 (it) Struttura di cannula vaginale monouso, per l'applicazione di pomate, medicamenti semidensi e simili.