SK282438B6 - Vakcínový prostriedok obsahujúci antigény proti malárii - Google Patents

Vakcínový prostriedok obsahujúci antigény proti malárii Download PDF

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Publication number
SK282438B6
SK282438B6 SK115-99A SK11599A SK282438B6 SK 282438 B6 SK282438 B6 SK 282438B6 SK 11599 A SK11599 A SK 11599A SK 282438 B6 SK282438 B6 SK 282438B6
Authority
SK
Slovakia
Prior art keywords
protein
malaria
vaccine composition
proteins
falciparum
Prior art date
Application number
SK115-99A
Other languages
English (en)
Slovak (sk)
Other versions
SK11599A3 (en
Inventor
Joseph Cohen
Original Assignee
Smithkline Beecham Biologicals S. A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Biologicals S. A. filed Critical Smithkline Beecham Biologicals S. A.
Publication of SK11599A3 publication Critical patent/SK11599A3/sk
Publication of SK282438B6 publication Critical patent/SK282438B6/sk

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/002Protozoa antigens
    • A61K39/015Hemosporidia antigens, e.g. Plasmodium antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/39Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/02Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/06Antimalarials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55566Emulsions, e.g. Freund's adjuvant, MF59
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55572Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55577Saponins; Quil A; QS21; ISCOMS
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/57Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • A61K2039/575Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 humoral response
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2730/00Reverse transcribing DNA viruses
    • C12N2730/00011Details
    • C12N2730/10011Hepadnaviridae
    • C12N2730/10111Orthohepadnavirus, e.g. hepatitis B virus
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
SK115-99A 1996-08-02 1997-07-31 Vakcínový prostriedok obsahujúci antigény proti malárii SK282438B6 (sk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9616351.4A GB9616351D0 (en) 1996-08-02 1996-08-02 Vaccine composition
PCT/EP1997/004326 WO1998005355A1 (fr) 1996-08-02 1997-07-31 Composition vaccinale contre le paludisme

Publications (2)

Publication Number Publication Date
SK11599A3 SK11599A3 (en) 2000-03-13
SK282438B6 true SK282438B6 (sk) 2002-02-05

Family

ID=10797980

Family Applications (1)

Application Number Title Priority Date Filing Date
SK115-99A SK282438B6 (sk) 1996-08-02 1997-07-31 Vakcínový prostriedok obsahujúci antigény proti malárii

Country Status (32)

Country Link
US (2) US20020172692A1 (fr)
EP (2) EP0957933B1 (fr)
JP (1) JP2000517295A (fr)
KR (1) KR20000029747A (fr)
CN (1) CN1241639C (fr)
AP (1) AP1166A (fr)
AR (1) AR008799A1 (fr)
AT (1) ATE394119T1 (fr)
AU (1) AU706303B2 (fr)
BG (1) BG63290B1 (fr)
BR (1) BR9710913A (fr)
CA (1) CA2262402A1 (fr)
CO (1) CO4650186A1 (fr)
CZ (1) CZ290826B6 (fr)
DE (1) DE69738672D1 (fr)
DZ (1) DZ2283A1 (fr)
EA (1) EA002167B1 (fr)
GB (1) GB9616351D0 (fr)
ID (1) ID17860A (fr)
IL (1) IL128318A (fr)
MA (1) MA24291A1 (fr)
MY (1) MY116128A (fr)
NO (1) NO319844B1 (fr)
OA (1) OA10969A (fr)
PE (1) PE97298A1 (fr)
PL (1) PL188741B1 (fr)
SK (1) SK282438B6 (fr)
TR (1) TR199900195T2 (fr)
UA (1) UA68336C2 (fr)
UY (1) UY24654A1 (fr)
WO (1) WO1998005355A1 (fr)
ZA (1) ZA976815B (fr)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9915204D0 (en) * 1999-06-29 1999-09-01 Smithkline Beecham Biolog Vaccine
PL376792A1 (pl) 2002-10-23 2006-01-09 Glaxosmithkline Biologicals S.A. Sposoby szczepienia przeciwko malarii
NZ548166A (en) * 2003-12-01 2010-06-25 Meiji Dairies Corp Peptide inhibiting angiontensin converting enzyme
GB0513421D0 (en) 2005-06-30 2005-08-03 Glaxosmithkline Biolog Sa Vaccines
PT1909830E (pt) * 2005-08-02 2011-11-24 Novartis Vaccines & Diagnostic Redução de interferência entre adjuvantes contendo óleo e antigénios contendo tensioactivos
GB0614254D0 (en) * 2006-07-18 2006-08-30 Smithkline Beecham Biolog Vaccine
AU2007276219B2 (en) * 2006-07-18 2013-10-03 Glaxosmithkline Biologicals S.A. Vaccines for malaria
ES2387582T3 (es) 2006-09-07 2012-09-26 Glaxosmithkline Biologicals S.A. Vacuna de combinación con cantidades reducidas del antígeno del virus de la polio
WO2009021931A1 (fr) 2007-08-13 2009-02-19 Glaxosmithkline Biologicals S.A. Vaccins
CN102026657A (zh) * 2007-12-21 2011-04-20 葛兰素史密丝克莱恩生物有限公司 疟疾疫苗
AP2010005294A0 (en) 2007-12-24 2010-06-30 Glaxosmithkline Biolog Sa Vaccines for malaria
EP2313108A4 (fr) * 2008-06-30 2013-06-12 Us Army As Represented By The Secretary Of The Army Vaccin antipaludéen de nanoparticules de polypeptide auto-assemblées
US20110104195A1 (en) * 2009-11-05 2011-05-05 Joao Aguiar Plasmodium falciparum sporozoite and liver stage antigens
BR112013004582A2 (pt) 2010-09-27 2016-09-06 Crucell Holland Bv método para induzir uma resposta imune em um sujeito contra um antígeno de um parasita que causa a malária
GB201116248D0 (en) 2011-09-20 2011-11-02 Glaxosmithkline Biolog Sa Liposome production using isopropanol
US20130122038A1 (en) 2011-11-14 2013-05-16 The United States Of America As Represented By The Secretary Of The Department Heterologous prime-boost immunization using measles virus-based vaccines
US9169304B2 (en) 2012-05-01 2015-10-27 Pfenex Inc. Process for purifying recombinant Plasmodium falciparum circumsporozoite protein
CN104338129B (zh) * 2013-07-26 2017-05-24 中国科学院上海巴斯德研究所 雷帕霉素作为疫苗佐剂的用途及制备方法
WO2018104313A1 (fr) 2016-12-07 2018-06-14 Glaxosmithkline Biologicals Sa Nouveau procédé
GB201621686D0 (en) 2016-12-20 2017-02-01 Glaxosmithkline Biologicals Sa Novel methods for inducing an immune response
BR112019025193A2 (pt) 2017-05-30 2020-06-23 Glaxosmithkline Biologicals S.A. Métodos de fabricação de um adjuvante lipossomal, de fabricação de um concentrado lipossomal, para a preparação de uma composição imunogênica com adjuvante e para a preparação de uma solução, adjuvante lipossomal, composição imunogênica com adjuvante, e, solução
CN111670044A (zh) 2017-12-01 2020-09-15 葛兰素史密丝克莱恩生物有限公司 皂苷纯化
CN114080393A (zh) 2019-06-05 2022-02-22 葛兰素史克生物有限公司 皂苷纯化

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0071705B1 (fr) * 1981-05-21 1989-11-23 The Wellcome Foundation Limited Antigène protozoaire
ES8800273A1 (es) * 1985-03-28 1987-11-01 Univ New York Perfeccionamientos en la fabricacion de conjugados de proteinas portadores de antigenos inmunogenicos para vacunas contra la malaria
GB8819209D0 (en) * 1988-08-12 1988-09-14 Research Corp Ltd Polypeptide & dna encoding same
GB9012580D0 (en) * 1990-06-06 1990-07-25 Univ Nijmegen Novel protein
FR2679776A1 (fr) * 1991-07-31 1993-02-05 Pasteur Institut Melange de constituants peptidiques ayant des proprietes vaccinantes contre le paludisme, notamment du a plasmodium falciparum.
KR100251505B1 (ko) * 1991-11-16 2000-05-01 장 스테판느 말라리아원충으로부터의 cs 및 hbsag 사이의 혼성 단백질(hybrid protein between cs from plasmodium and hbsag)
US6169171B1 (en) * 1992-02-27 2001-01-02 Smithkline Beecham Biologicals (S.A.) Hybrid protein between CS from plasmodium and HBSAG
KR100278157B1 (ko) * 1992-06-25 2001-01-15 장 스테판느 보조약을 함유하는 백신 조성물
GB9326253D0 (en) * 1993-12-23 1994-02-23 Smithkline Beecham Biolog Vaccines
AUPM368994A0 (en) * 1994-02-04 1994-02-24 Saramane Pty Ltd Malaria merozoite antigen subunit vaccine
FR2744723A1 (fr) * 1996-02-14 1997-08-14 Pasteur Institut Proteine recombinante contenant un fragment c-terminal d'une proteine msp-1 d'un plasmodium infectieux pour l'homme pour la production de vaccins anti-paludiques
FR2744724B1 (fr) * 1996-02-14 2002-08-02 Pasteur Institut Proteine recombinante contenant un fragment c-terminal de la proteine msp-1 d'un plasmodium infectieux pour l'homme pour la production de vaccins anti-paludiques

Also Published As

Publication number Publication date
SK11599A3 (en) 2000-03-13
IL128318A (en) 2002-04-21
DE69738672D1 (de) 2008-06-19
BG63290B1 (bg) 2001-09-28
EP0957933B1 (fr) 2008-05-07
ATE394119T1 (de) 2008-05-15
WO1998005355A1 (fr) 1998-02-12
CO4650186A1 (es) 1998-09-03
AR008799A1 (es) 2000-02-23
MA24291A1 (fr) 1998-04-01
US20060292170A1 (en) 2006-12-28
BR9710913A (pt) 1999-08-17
NO319844B1 (no) 2005-09-19
KR20000029747A (ko) 2000-05-25
PL188741B1 (pl) 2005-04-29
CN1241639C (zh) 2006-02-15
CZ29299A3 (cs) 1999-06-16
PE97298A1 (es) 1999-02-14
PL331424A1 (en) 1999-07-19
EP1623720A3 (fr) 2006-02-22
BG103141A (en) 1999-08-31
EP1623720A2 (fr) 2006-02-08
NO990464D0 (no) 1999-02-01
JP2000517295A (ja) 2000-12-26
EA199900069A1 (ru) 1999-10-28
CA2262402A1 (fr) 1998-02-12
UA68336C2 (en) 2004-08-16
US20020172692A1 (en) 2002-11-21
ID17860A (id) 1998-01-29
MY116128A (en) 2003-11-28
AP9901448A0 (en) 1999-03-31
CZ290826B6 (cs) 2002-10-16
GB9616351D0 (en) 1996-09-11
OA10969A (en) 2003-03-04
ZA976815B (en) 1998-05-11
UY24654A1 (es) 2001-08-27
DZ2283A1 (fr) 2002-12-25
IL128318A0 (en) 2000-01-31
EP0957933A1 (fr) 1999-11-24
CN1231613A (zh) 1999-10-13
AU706303B2 (en) 1999-06-10
AU4204097A (en) 1998-02-25
NO990464L (no) 1999-02-01
EA002167B1 (ru) 2002-02-28
TR199900195T2 (xx) 1999-04-21
AP1166A (en) 2003-06-30

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