SK279409B6 - Benzimidazoly, spôsob ich výroby a liečivo s ich o - Google Patents
Benzimidazoly, spôsob ich výroby a liečivo s ich o Download PDFInfo
- Publication number
- SK279409B6 SK279409B6 SK3944-92A SK394492A SK279409B6 SK 279409 B6 SK279409 B6 SK 279409B6 SK 394492 A SK394492 A SK 394492A SK 279409 B6 SK279409 B6 SK 279409B6
- Authority
- SK
- Slovakia
- Prior art keywords
- methyl
- imidazol
- group
- biphenyl
- benzimidazol
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Ophthalmology & Optometry (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Toys (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Instructional Devices (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE4201554A DE4201554A1 (de) | 1992-01-22 | 1992-01-22 | Benzimidazole, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung |
| DE4219782A DE4219782A1 (de) | 1992-01-22 | 1992-06-17 | Benzimidazole, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung |
| DE4225756A DE4225756A1 (de) | 1992-01-22 | 1992-08-04 | Benzimidazole, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| SK279409B6 true SK279409B6 (sk) | 1998-11-04 |
| SK394492A3 SK394492A3 (en) | 1998-11-04 |
Family
ID=27203316
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SK3944-92A SK394492A3 (en) | 1992-01-22 | 1992-12-29 | Benzimidazoles, process for their preparation and drug containing the same |
Country Status (18)
| Country | Link |
|---|---|
| EP (1) | EP0552765B1 (cs) |
| JP (1) | JPH05279341A (cs) |
| AT (1) | ATE141270T1 (cs) |
| AU (1) | AU660209B2 (cs) |
| CA (1) | CA2087800A1 (cs) |
| CZ (1) | CZ394492A3 (cs) |
| DE (2) | DE4225756A1 (cs) |
| DK (1) | DK0552765T3 (cs) |
| ES (1) | ES2093286T3 (cs) |
| FI (1) | FI930236A (cs) |
| GR (1) | GR3021303T3 (cs) |
| HU (1) | HU217816B (cs) |
| IL (1) | IL104485A (cs) |
| MX (1) | MX9300306A (cs) |
| NO (1) | NO303689B1 (cs) |
| NZ (1) | NZ245741A (cs) |
| PL (1) | PL172782B1 (cs) |
| SK (1) | SK394492A3 (cs) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2115985A1 (en) * | 1993-02-25 | 1994-08-26 | Kohei Nishikawa | Vascular hypertrophy suppressor |
| EP2448575A2 (en) | 2009-07-02 | 2012-05-09 | Bilgic Mahmut | Pharmaceutical composition increasing solubility and stability |
| EP2448576A2 (en) | 2009-07-02 | 2012-05-09 | Mahmut Bilgic | Solubility enhancing pharmaceutical composition |
| EP2377521A1 (en) | 2010-03-26 | 2011-10-19 | Abdi Ibrahim Ilac Sanayi ve Ticaret Anonim Sirketi | Pharmaceutical formulations of telmisartan and diuretic combination |
| ES2806135T3 (es) | 2013-06-21 | 2021-02-16 | Zenith Epigenetics Ltd | Nuevos inhibidores de bromodominios bicíclicos |
| JP6599852B2 (ja) | 2013-06-21 | 2019-10-30 | ゼニス・エピジェネティクス・リミテッド | ブロモドメイン阻害剤としての新規の置換された二環式化合物 |
| CN105593224B (zh) | 2013-07-31 | 2021-05-25 | 恒元生物医药科技(苏州)有限公司 | 作为溴结构域抑制剂的新型喹唑啉酮类化合物 |
| CA2966298A1 (en) | 2014-12-01 | 2016-06-09 | Zenith Epigenetics Ltd. | Substituted pyridinones as bromodomain inhibitors |
| JP2017537946A (ja) | 2014-12-11 | 2017-12-21 | ゼニス・エピジェネティクス・リミテッドＺｅｎｉｔｈ Ｅｐｉｇｅｎｅｔｉｃｓ Ｌｔｄ． | ブロモドメイン阻害剤としての置換複素環 |
| CA2966450A1 (en) | 2014-12-17 | 2016-06-23 | Olesya KHARENKO | Inhibitors of bromodomains |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3928177A1 (de) * | 1989-04-08 | 1991-02-28 | Thomae Gmbh Dr K | Benzimidazole, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung |
| EP0400835A1 (en) * | 1989-05-15 | 1990-12-05 | Merck & Co. Inc. | Substituted benzimidazoles as angiotensin II antagonists |
| RU1836357C (ru) * | 1990-07-23 | 1993-08-23 | Др.Карл Томэ ГмбХ | Производные бензимидазола, их изомеры, смеси изомеров, гидраты или их физиологически переносимые соли, обладающие антагонистическими в отношении ангиотензина свойствами |
| SI9210098B (sl) | 1991-02-06 | 2000-06-30 | Dr. Karl Thomae | Benzimidazoli, zdravila, ki te spojine vsebujejo, in postopek za njihovo pripravo |
-
1992
- 1992-08-04 DE DE4225756A patent/DE4225756A1/de not_active Withdrawn
- 1992-12-29 SK SK3944-92A patent/SK394492A3/sk unknown
- 1992-12-29 CZ CS923944A patent/CZ394492A3/cs unknown
-
1993
- 1993-01-20 PL PL93297472A patent/PL172782B1/pl unknown
- 1993-01-21 DK DK93100890.8T patent/DK0552765T3/da active
- 1993-01-21 JP JP5008004A patent/JPH05279341A/ja active Pending
- 1993-01-21 CA CA002087800A patent/CA2087800A1/en not_active Abandoned
- 1993-01-21 AT AT93100890T patent/ATE141270T1/de not_active IP Right Cessation
- 1993-01-21 DE DE59303388T patent/DE59303388D1/de not_active Expired - Fee Related
- 1993-01-21 EP EP93100890A patent/EP0552765B1/de not_active Expired - Lifetime
- 1993-01-21 MX MX9300306A patent/MX9300306A/es not_active IP Right Cessation
- 1993-01-21 HU HU9300168A patent/HU217816B/hu not_active IP Right Cessation
- 1993-01-21 NO NO930205A patent/NO303689B1/no unknown
- 1993-01-21 ES ES93100890T patent/ES2093286T3/es not_active Expired - Lifetime
- 1993-01-21 FI FI930236A patent/FI930236A/fi unknown
- 1993-01-22 AU AU31962/93A patent/AU660209B2/en not_active Ceased
- 1993-01-22 IL IL10448593A patent/IL104485A/en not_active IP Right Cessation
- 1993-01-22 NZ NZ245741A patent/NZ245741A/en unknown
-
1996
- 1996-10-09 GR GR960402674T patent/GR3021303T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NO303689B1 (no) | 1998-08-17 |
| DK0552765T3 (da) | 1997-01-13 |
| EP0552765A1 (de) | 1993-07-28 |
| EP0552765B1 (de) | 1996-08-14 |
| CA2087800A1 (en) | 1993-07-23 |
| PL297472A1 (en) | 1994-01-24 |
| JPH05279341A (ja) | 1993-10-26 |
| HUT63626A (en) | 1993-09-28 |
| CZ394492A3 (en) | 1993-11-17 |
| HU9300168D0 (en) | 1993-04-28 |
| DE4225756A1 (de) | 1994-03-10 |
| HU217816B (hu) | 2000-04-28 |
| MX9300306A (es) | 1993-07-01 |
| GR3021303T3 (en) | 1997-01-31 |
| AU660209B2 (en) | 1995-06-15 |
| NO930205D0 (no) | 1993-01-21 |
| NO930205L (no) | 1993-07-23 |
| NZ245741A (en) | 1995-07-26 |
| AU3196293A (en) | 1993-07-29 |
| IL104485A (en) | 1999-10-28 |
| FI930236A0 (fi) | 1993-01-21 |
| ATE141270T1 (de) | 1996-08-15 |
| IL104485A0 (en) | 1993-05-13 |
| FI930236A (fi) | 1993-07-23 |
| DE59303388D1 (de) | 1996-09-19 |
| SK394492A3 (en) | 1998-11-04 |
| PL172782B1 (pl) | 1997-11-28 |
| ES2093286T3 (es) | 1996-12-16 |
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