SK278137B6 - Tripeptide derivative, method of its preparation and pharmaceutical agent containing this derivative - Google Patents

Tripeptide derivative, method of its preparation and pharmaceutical agent containing this derivative Download PDF

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Publication number
SK278137B6
SK278137B6 SK3323-87A SK332387A SK278137B6 SK 278137 B6 SK278137 B6 SK 278137B6 SK 332387 A SK332387 A SK 332387A SK 278137 B6 SK278137 B6 SK 278137B6
Authority
SK
Slovakia
Prior art keywords
group
alkyl
carbon atoms
formula
gamma
Prior art date
Application number
SK3323-87A
Other languages
English (en)
Slovak (sk)
Other versions
SK332387A3 (en
Inventor
Tadahiro Sawayama
Masatoshi Tsukamoto
Takashi Sasagawa
Kazuya Nishimura
Kanoo Hosoki
Kunihiko Takeyama
Original Assignee
Tadahiro Sawayama
Masatoshi Tsukamoto
Takashi Sasagawa
Kazuya Nishimura
Kanoo Hosoki
Kunihiko Takeyama
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tadahiro Sawayama, Masatoshi Tsukamoto, Takashi Sasagawa, Kazuya Nishimura, Kanoo Hosoki, Kunihiko Takeyama filed Critical Tadahiro Sawayama
Publication of SK278137B6 publication Critical patent/SK278137B6/sk
Publication of SK332387A3 publication Critical patent/SK332387A3/sk

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06086—Dipeptides with the first amino acid being basic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0215—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing natural amino acids, forming a peptide bond via their side chain functional group, e.g. epsilon-Lys, gamma-Glu
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
SK3323-87A 1986-05-09 1987-05-08 Tripeptide derivative, method of its prepartion and pharmaceutical agent containing this derivative SK332387A3 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP10739486 1986-05-09
JP15669386 1986-07-03
JP1636187 1987-01-26

Publications (2)

Publication Number Publication Date
SK278137B6 true SK278137B6 (en) 1996-02-07
SK332387A3 SK332387A3 (en) 1996-02-07

Family

ID=27281373

Family Applications (1)

Application Number Title Priority Date Filing Date
SK3323-87A SK332387A3 (en) 1986-05-09 1987-05-08 Tripeptide derivative, method of its prepartion and pharmaceutical agent containing this derivative

Country Status (16)

Country Link
US (1) US4826814A (es)
EP (1) EP0244836B1 (es)
JP (1) JPS63295597A (es)
KR (1) KR870011152A (es)
AU (1) AU595309B2 (es)
CA (1) CA1318461C (es)
CZ (1) CZ280776B6 (es)
DE (1) DE3787042T2 (es)
DK (1) DK171402B1 (es)
ES (1) ES2058074T3 (es)
FI (1) FI87794C (es)
HU (1) HU202884B (es)
MX (1) MX174530B (es)
NZ (1) NZ220173A (es)
SK (1) SK332387A3 (es)
SU (1) SU1743356A3 (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0394311A1 (en) * 1987-11-16 1990-10-31 The Upjohn Company Renin inhibiting peptides that contain amino and hydroxy dicarboxylic acids
FR2649110B1 (fr) * 1989-06-29 1994-10-21 Adir Nouveaux derives peptidiques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
US5391705A (en) * 1991-03-15 1995-02-21 Merrell Dow Pharmaceuticals Inc. Polyfluorinated tripeptide thrombin inhibitors
US6764693B1 (en) 1992-12-11 2004-07-20 Amaox, Ltd. Free radical quenching composition and a method to increase intracellular and/or extracellular antioxidants
US5925452A (en) * 1994-05-27 1999-07-20 Cubic Co., Ltd. Decorated shaped product having source expression applied thereto, method for manufacturing same and shaped base material therefor
AU5514496A (en) * 1995-04-27 1996-11-18 Dainippon Pharmaceutical Co. Ltd. Purifying methods
US6069232A (en) * 1995-10-02 2000-05-30 Hoechst Marion Roussel, Inc. Polyfluoroalkyl tryptophan tripeptide thrombin inhibitors
US5739354A (en) * 1996-03-26 1998-04-14 Hoechst Marion Roussel, Inc. Process for the preparation of N-methyl-D-phenylalanyl-N- 1- 3- (aminoiminomethyl)amino!propyl!-3,3-difluoro-2-oxohexyl!-L-prolinamide
JP2005519098A (ja) * 2002-03-01 2005-06-30 ワーナー−ランバート・カンパニー、リミテッド、ライアビリティ、カンパニー 変形性関節症の治療方法
CN114920676B (zh) * 2022-06-07 2024-04-05 四川国康药业有限公司 一种治疗呼吸系统疾病的化合物及其制备方法和用途

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4215110A (en) * 1978-09-22 1980-07-29 Merck & Co., Inc. Method of treating hypertension
DE3381378D1 (de) * 1982-01-23 1990-05-03 Ajinomoto Kk Derivate von aminosaeuren und antihypertensive arzneimittel diese enthaltend.
JPS59227851A (ja) * 1983-06-09 1984-12-21 Sankyo Co Ltd レニン阻害作用を有するペプチド類
US4678800A (en) * 1984-06-15 1987-07-07 Ciba-Geigy Corporation Gamma-r-glutamoyl derivatives
US4616002A (en) * 1984-11-09 1986-10-07 Ciba-Geigy Corporation Dihydro pyridine compounds, compositions and use
DE3619633A1 (de) * 1986-06-11 1987-12-17 Hoechst Ag Peptide mit einfluss auf die diurese und natriurese, verfahren zu ihrer herstellung, diese enthaltende mittel und ihre verwendung
DE3640535A1 (de) * 1986-11-27 1988-06-01 Merck Patent Gmbh Peptide
DK523288A (da) * 1987-10-06 1989-04-07 Hoffmann La Roche Aminosyrederivater

Also Published As

Publication number Publication date
AU7241687A (en) 1987-11-12
DK235787A (da) 1987-11-10
FI87794C (fi) 1993-02-25
FI87794B (fi) 1992-11-13
CZ280776B6 (cs) 1996-04-17
EP0244836A2 (en) 1987-11-11
EP0244836A3 (en) 1989-11-23
AU595309B2 (en) 1990-03-29
US4826814A (en) 1989-05-02
FI872041A (fi) 1987-11-10
DK235787D0 (da) 1987-05-08
CZ332387A3 (en) 1995-11-15
DE3787042D1 (de) 1993-09-23
HUT45268A (en) 1988-06-28
SK332387A3 (en) 1996-02-07
EP0244836B1 (en) 1993-08-18
DK171402B1 (da) 1996-10-14
DE3787042T2 (de) 1994-01-27
KR870011152A (ko) 1987-12-21
HU202884B (en) 1991-04-29
CA1318461C (en) 1993-05-25
FI872041A0 (fi) 1987-05-08
JPS63295597A (ja) 1988-12-01
NZ220173A (en) 1990-01-29
ES2058074T3 (es) 1994-11-01
MX6424A (es) 1993-09-01
MX174530B (es) 1994-05-24
SU1743356A3 (ru) 1992-06-23

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