SK152698A3 - Cationic virosomes as transfer system for genetic material - Google Patents

Cationic virosomes as transfer system for genetic material Download PDF

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Publication number
SK152698A3
SK152698A3 SK1526-98A SK152698A SK152698A3 SK 152698 A3 SK152698 A3 SK 152698A3 SK 152698 A SK152698 A SK 152698A SK 152698 A3 SK152698 A3 SK 152698A3
Authority
SK
Slovakia
Prior art keywords
cell
membrane
virosomes
group
cationic
Prior art date
Application number
SK1526-98A
Other languages
English (en)
Slovak (sk)
Inventor
Ernst R Walti
Reinhard Gluck
Peter Klein
Original Assignee
Nika Health Products Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nika Health Products Ltd filed Critical Nika Health Products Ltd
Publication of SK152698A3 publication Critical patent/SK152698A3/sk

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Liposomes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Liposomes
    • A61K9/1271Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Liposomes
    • A61K9/1271Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
    • A61K9/1272Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers with substantial amounts of non-phosphatidyl, i.e. non-acylglycerophosphate, surfactants as bilayer-forming substances, e.g. cationic lipids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/87Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/88Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation using microencapsulation, e.g. using amphiphile liposome vesicle

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Dispersion Chemistry (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Plant Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
SK1526-98A 1996-05-08 1997-05-04 Cationic virosomes as transfer system for genetic material SK152698A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP96107282 1996-05-08
PCT/EP1997/002268 WO1997041834A1 (en) 1996-05-08 1997-05-04 Cationic virosomes as transfer system for genetic material

Publications (1)

Publication Number Publication Date
SK152698A3 true SK152698A3 (en) 1999-05-07

Family

ID=8222763

Family Applications (1)

Application Number Title Priority Date Filing Date
SK1526-98A SK152698A3 (en) 1996-05-08 1997-05-04 Cationic virosomes as transfer system for genetic material

Country Status (28)

Country Link
US (1) US6210708B1 (bg)
EP (1) EP0902682A2 (bg)
JP (1) JP2000509404A (bg)
KR (1) KR100536983B1 (bg)
CN (1) CN1271992C (bg)
AR (1) AR007054A1 (bg)
AU (1) AU710170B2 (bg)
BG (1) BG102880A (bg)
BR (1) BR9709224A (bg)
CA (1) CA2253561A1 (bg)
CO (1) CO4600638A1 (bg)
CZ (1) CZ299809B6 (bg)
EA (1) EA003130B1 (bg)
GT (1) GT199700058A (bg)
HR (1) HRP970234B1 (bg)
HU (1) HUP9901790A3 (bg)
ID (1) ID17934A (bg)
NO (1) NO327726B1 (bg)
NZ (1) NZ332666A (bg)
OA (1) OA10916A (bg)
PA (1) PA8429201A1 (bg)
PE (1) PE65198A1 (bg)
PL (1) PL199201B1 (bg)
SK (1) SK152698A3 (bg)
SV (1) SV1997000032A (bg)
TN (1) TNSN97080A1 (bg)
WO (1) WO1997041834A1 (bg)
ZA (1) ZA973885B (bg)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030113347A1 (en) * 1991-05-08 2003-06-19 Schweiz. Serum- & Impfinstitut Bern Immunostimulating and immunopotentiating reconstituted influenza virosomes and vaccines containing them
AU9224398A (en) * 1997-09-08 1999-03-29 Promega Corporation Method of (in vivo) transformation utilizing lipid vehicles
SE513149C2 (sv) * 1997-12-05 2000-07-17 Katarina Edwards Läkemedelsdistributionssystem med tvåstegsmålsökning, till specifika celler eller vävnad och till dess cellkärna
ATE258428T1 (de) * 1999-10-08 2004-02-15 Nika Health Products Ltd Kationische dosper virosomen
BR0016472A (pt) * 1999-12-17 2002-08-20 Cápsula de ignição indutivamente ativável para sistemas de retenção de ocupantes de assento
WO2001052901A1 (fr) * 2000-01-21 2001-07-26 Hisamitsu Pharmaceutical Co., Inc. Medicaments pour la therapie genique
US20030021768A1 (en) * 2001-07-23 2003-01-30 Yuqiao Shen Viral mutants that selectively replicate in targeted human cancer cells
KR100411234B1 (ko) * 2001-08-14 2003-12-18 한국과학기술원 올리고뉴클레오티드 혼성화 미셀 및 그의 제조방법
WO2003038103A1 (en) * 2001-10-29 2003-05-08 Atso Raasmaja Method for gene transfection using synergistic combinations of cationic lipids and cationic polymers
US20040028687A1 (en) * 2002-01-15 2004-02-12 Waelti Ernst Rudolf Methods and compositions for the targeted delivery of therapeutic substances to specific cells and tissues
US20040176283A1 (en) * 2002-04-01 2004-09-09 Robinson John A. Methods and compositions for the design of synthetic vaccines
EA008497B1 (ru) * 2002-11-21 2007-06-29 Певион Биотех Лтд. Высокоэффективные способные к слиянию везикулы, способ их получения и фармацевтическая композиция, их содержащая
US8062891B2 (en) 2003-10-24 2011-11-22 Gencia Corporation Nonviral vectors for delivering polynucleotides to plants
US20090123468A1 (en) 2003-10-24 2009-05-14 Gencia Corporation Transducible polypeptides for modifying metabolism
US20090208478A1 (en) * 2003-10-24 2009-08-20 Gencia Corporation Transducible polypeptides for modifying metabolism
US8133733B2 (en) 2003-10-24 2012-03-13 Gencia Corporation Nonviral vectors for delivering polynucleotides to target tissues
US8507277B2 (en) 2003-10-24 2013-08-13 Gencia Corporation Nonviral vectors for delivering polynucleotides
JP4838722B2 (ja) 2003-10-24 2011-12-14 ゲンシア コーポレーション ポリヌクレオチドを送達する方法、及び送達用組成物
DE102004057303A1 (de) * 2004-11-26 2006-06-01 Merck Patent Gmbh Stabile Kristallmodifikationen von DOTAP Chlorid
US20070172520A1 (en) * 2005-11-18 2007-07-26 University Of South Florida Immunotargeting of Nonionic Surfactant Vesicles
JP5606067B2 (ja) 2006-09-15 2014-10-15 オタワ ホスピタル リサーチ インスティテュート 腫瘍崩壊性ラブドウイルス
KR101242113B1 (ko) * 2010-10-22 2013-03-19 고마바이오텍(주) 유전자 전달용 양이온성 센다이 f/hn 바이로좀 복합체
WO2013032643A2 (en) * 2011-08-31 2013-03-07 Dicerna Pharmaceuticals, Inc. Lipids capable of conformational change and their use in formulations to deliver therapeutic agents to cells
US20140335117A1 (en) * 2011-10-07 2014-11-13 Skau Aps Identification and Attenuation of the Immunosuppressive Domains in Fusion Proteins of Enveloped RNA Viruses
AU2017336199B2 (en) 2016-09-27 2020-08-20 Camurus Ab Mixtures and formulations comprising an alkyl ammonium EDTA salt
CN109055432B (zh) * 2018-08-16 2020-10-13 南京科佰生物科技有限公司 慢病毒感染试剂及其制备方法与应用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4261975A (en) 1979-09-19 1981-04-14 Merck & Co., Inc. Viral liposome particle
US5264618A (en) * 1990-04-19 1993-11-23 Vical, Inc. Cationic lipids for intracellular delivery of biologically active molecules
PL296382A1 (en) * 1991-02-02 1993-11-02 Nika Health Products Ltd Li Li Artificial membrane beads containing functionally active peptides responsible for fusion as a drug administering system
EP0538437B1 (en) * 1991-05-08 1999-08-04 SCHWEIZ. SERUM- & IMPFINSTITUT BERN Immunostimulating and immunopotentiating reconstituted influenza virosomes and vaccines containing them
WO1993014744A1 (en) 1992-02-04 1993-08-05 Chiron Corporation Non-toxic lipid vaccine formulations
US5631237A (en) 1992-12-22 1997-05-20 Dzau; Victor J. Method for producing in vivo delivery of therapeutic agents via liposomes
US5578475A (en) * 1993-07-12 1996-11-26 Life Technologies, Inc. Composition and methods for transfecting eukaryotic cells
ATE223701T1 (de) * 1994-05-31 2002-09-15 Inex Pharmaceutical Corp Intrazelluläre verabreichung therapeutischer sustanzenmittels virosomen
FR2726764B1 (fr) 1994-11-14 1997-01-31 Pasteur Merieux Serums Vacc Adjuvant pour composition vaccinale

Also Published As

Publication number Publication date
AR007054A1 (es) 1999-10-13
CN1271992C (zh) 2006-08-30
GT199700058A (es) 1998-10-29
NO327726B1 (no) 2009-09-14
EA003130B1 (ru) 2003-02-27
KR100536983B1 (ko) 2006-06-29
WO1997041834A1 (en) 1997-11-13
HUP9901790A2 (hu) 1999-08-30
HRP970234A2 (en) 1998-06-30
SV1997000032A (es) 1998-03-27
CO4600638A1 (es) 1998-05-08
PL199201B1 (pl) 2008-08-29
EP0902682A2 (en) 1999-03-24
KR20000010780A (ko) 2000-02-25
AU710170B2 (en) 1999-09-16
PA8429201A1 (es) 2000-05-24
AU2776697A (en) 1997-11-26
CZ361498A3 (cs) 1999-03-17
HRP970234B1 (en) 2002-04-30
CA2253561A1 (en) 1997-11-13
TNSN97080A1 (fr) 2005-03-15
CZ299809B6 (cs) 2008-12-03
HUP9901790A3 (en) 2010-11-29
ZA973885B (en) 1998-11-06
CN1225007A (zh) 1999-08-04
ID17934A (id) 1998-02-12
US6210708B1 (en) 2001-04-03
EA199800992A1 (ru) 1999-06-24
NO985137D0 (no) 1998-11-04
JP2000509404A (ja) 2000-07-25
PL329853A1 (en) 1999-04-12
NZ332666A (en) 2000-05-26
PE65198A1 (es) 1998-10-16
BR9709224A (pt) 1999-08-10
BG102880A (bg) 1999-05-31
OA10916A (en) 2003-02-21
NO985137L (no) 1999-01-04

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