SK1402003A3 - Oxazolidinone derivatives as antimicrobials - Google Patents

Oxazolidinone derivatives as antimicrobials Download PDF

Info

Publication number
SK1402003A3
SK1402003A3 SK140-2003A SK1402003A SK1402003A3 SK 1402003 A3 SK1402003 A3 SK 1402003A3 SK 1402003 A SK1402003 A SK 1402003A SK 1402003 A3 SK1402003 A3 SK 1402003A3
Authority
SK
Slovakia
Prior art keywords
methyl
acetamide
oxo
fluoro
oxazolidinyl
Prior art date
Application number
SK140-2003A
Other languages
English (en)
Slovak (sk)
Inventor
Anita Mehta
Sudershan K Arora
Biswajit Das
Abhijit Ray
Sonali Rudra
Ashok Rattan
Original Assignee
Ranbaxy Lab Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ranbaxy Lab Ltd filed Critical Ranbaxy Lab Ltd
Publication of SK1402003A3 publication Critical patent/SK1402003A3/sk

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
SK140-2003A 2000-07-17 2001-07-16 Oxazolidinone derivatives as antimicrobials SK1402003A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN654DE2000 2000-07-17
PCT/IB2001/001262 WO2002006278A1 (en) 2000-07-17 2001-07-16 Oxazolidinone derivatives as antimicrobials

Publications (1)

Publication Number Publication Date
SK1402003A3 true SK1402003A3 (en) 2003-08-05

Family

ID=11097070

Family Applications (1)

Application Number Title Priority Date Filing Date
SK140-2003A SK1402003A3 (en) 2000-07-17 2001-07-16 Oxazolidinone derivatives as antimicrobials

Country Status (16)

Country Link
US (2) US6734307B2 (ru)
EP (1) EP1303511A1 (ru)
JP (1) JP2004504321A (ru)
CN (1) CN1447808A (ru)
AU (2) AU6937001A (ru)
BR (1) BR0112826A (ru)
CA (1) CA2415965A1 (ru)
CZ (1) CZ2003228A3 (ru)
HU (1) HUP0302918A2 (ru)
MX (1) MXPA03000503A (ru)
NZ (1) NZ523700A (ru)
PL (1) PL363960A1 (ru)
RU (1) RU2292345C9 (ru)
SK (1) SK1402003A3 (ru)
WO (1) WO2002006278A1 (ru)
ZA (1) ZA200300471B (ru)

Families Citing this family (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9928568D0 (en) 1999-12-03 2000-02-02 Zeneca Ltd Chemical compounds
GB0009803D0 (en) * 2000-04-25 2000-06-07 Astrazeneca Ab Chemical compounds
WO2003008389A1 (en) * 2001-07-16 2003-01-30 Ranbaxy Laboratories Limited Oxazolidinone derivatives as potential antimicrobials
EP1303511A1 (en) 2000-07-17 2003-04-23 Ranbaxy Laboratories, Ltd. Oxazolidinone derivatives as antimicrobials
ES2248633T3 (es) * 2001-04-17 2006-03-16 MERCK & CO., INC. Antibioticos oxazolidinona que contienen biciclo (3,1,o)hexano y derivados de los mismos.
US6956040B2 (en) 2001-07-16 2005-10-18 Ranbaxy Laboratories Limited Oxazolidinone piperazinyl derivatives as potential antimicrobials
FR2828488B1 (fr) * 2001-08-08 2005-06-10 Oreal Composition pour la teinture de fibres keratiniques contenant une paraphenylenediamine substituee par un radical diazacycloheptane
US20060229316A1 (en) * 2002-04-01 2006-10-12 Lohray Braj B Novel antiinfective compounds, process for their preparation and pharmaceutical compositions containing them
WO2003093247A2 (en) * 2002-04-30 2003-11-13 Orchid Chemicals & Pharmaceuticals Ltd Antibacterial agents
WO2003097059A1 (en) * 2002-05-15 2003-11-27 Ranbaxy Laboratories Limited Polymorphic forms of phenyl oxazolidinone derivatives
WO2003097640A1 (en) * 2002-05-22 2003-11-27 Orchid Chemicals & Pharmaceuticals Ltd. Oxazolidinone derivatives as antibacterial agents
EA200500283A1 (ru) * 2002-07-29 2005-08-25 Рэнбакси Лабораториз Лимитед Производные оксазолидинона как противомикробные средства
AU2003253141A1 (en) 2002-08-22 2004-03-11 Orchid Chemicals And Pharmaceuticals Ltd Novel antibacterial agents
WO2004026848A1 (en) 2002-09-20 2004-04-01 Lupin Limited Oxazolidinone derivatives, process for their preperation and their use as antimycobacterial agents
US6875784B2 (en) 2002-10-09 2005-04-05 Pharmacia & Upjohn Company Antimibicrobial [3.1.0.] bicyclic oxazolidinone derivatives
GB0302094D0 (en) 2003-01-29 2003-02-26 Pharmagene Lab Ltd EP4 receptor antagonists
WO2004069816A1 (en) * 2003-02-07 2004-08-19 Ranbaxy Laboratories Limited Oxazolidinone derivatives as antimicrobials
US7223788B2 (en) 2003-02-14 2007-05-29 Sanofi-Aventis Deutschland Gmbh Substituted N-aryl heterocycles, process for their preparation and their use as medicaments
DE10306250A1 (de) * 2003-02-14 2004-09-09 Aventis Pharma Deutschland Gmbh Substituierte N-Arylheterozyklen, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
US20080214565A1 (en) * 2003-04-07 2008-09-04 Anita Mehta Oxazolidinone Derivatives as Antimicrobials
WO2004089943A1 (en) 2003-04-09 2004-10-21 Pharmacia & Upjohn Company Llc Antimicrobial [3.1.0] bicyclohexylphenyl-oxazolidinone derivatives and analogues
WO2005003087A2 (en) * 2003-07-01 2005-01-13 Orchid Chemicals And Pharmaceuticals Ltd. Oxazole derivatives as antibacterial agents
CA2529294A1 (en) * 2003-07-02 2005-01-20 Merck & Co., Inc. Oxazolidinone antibiotics and derivatives thereof
WO2005005399A1 (en) * 2003-07-02 2005-01-20 Merck & Co., Inc. Oxazolidinone antibiotics and derivatives thereof
KR20060113625A (ko) 2003-07-02 2006-11-02 머크 앤드 캄파니 인코포레이티드 시클로프로필기 치환된 옥사졸리디논 항생제 및 그의유도체
AU2004256085B2 (en) * 2003-07-02 2007-12-06 Kyorin, Pharmaceutical Co., Ltd. Cyclopropyl Group Substituted Oxazolydinone Antibiotics and Derivatives Thereof
GB0324269D0 (en) 2003-10-16 2003-11-19 Pharmagene Lab Ltd EP4 receptor antagonists
WO2005051933A1 (en) * 2003-11-28 2005-06-09 Ranbaxy Laboratories Limited An improved process for the synthesis of 4-(4-benzyloxy-carbonylamino-2-fluorophenyl)-piperazine-1-carboxylic acid tert-butyl ester, a key intermediate for oxazolidinone antimicrobials and compounds prepared thereby
WO2005082899A1 (en) * 2004-01-28 2005-09-09 Ranbaxy Laboratories Limited Oxazolidinone derivatives as antimicrobials
WO2006040614A1 (en) * 2004-10-11 2006-04-20 Ranbaxy Laboratories Limited Substituted oxazolidinone derivatives
DE602006010702D1 (de) 2005-06-29 2010-01-07 Pharmacia & Upjohn Co Llc Homomorpholinoxazolidinone als antibakterielle mittel
FR2895735B1 (fr) 2005-12-30 2008-04-18 Ecopack France Valve a poche amelioree
US7728031B2 (en) 2006-02-24 2010-06-01 Abbott Laboratories Octahydro-pyrrolo[3,4-b]pyrrole derivatives
CN101460495B (zh) 2006-03-31 2013-08-14 财团法人乙卯研究所 具有杂环的化合物
CN101809021B (zh) 2007-09-11 2013-04-24 雅培制药有限公司 八氢-吡咯并[3,4-b]吡咯n-氧化物
EP2233484A3 (en) 2007-10-02 2012-04-04 Research Foundation Itsuu Laboratory Oxazolidinone derivatives having a 7-membered heterocyclic ring
WO2009132310A1 (en) * 2008-04-25 2009-10-29 Wisconsin Alumni Research Foundation Inhibitors of udp-galactopyranose mutase thwart mycobacterial growth
US20130296569A1 (en) 2010-11-03 2013-11-07 Vijaykumar Jagdishwar Patil Process for the preparation of phosphoric acid mono-(1--4-methoxymethyl-piperidin-4-yl) ester
UA112876C2 (uk) 2011-09-29 2016-11-10 Сюаньчжу Фарма Ко., Лтд. Біарилгетероциклзаміщені оксазолідинонові антибактеріальні засоби
WO2015173664A1 (en) 2014-05-14 2015-11-19 Wockhardt Limited Process for the preparation of (5s)-n-{3-[3,5-difluoro-4-(4-hydroxy-4-methoxymethyl-piperidin-1-yl)-phenyl]-2-oxo-oxazolidin-5-ylmethyl}-acetamide
US10080757B2 (en) 2016-03-11 2018-09-25 Wisconsin Alumni Research Foundation Inhibitors of UDP-galactopyranose mutase
CN109020873B (zh) * 2018-07-16 2020-04-28 青岛农业大学 以靶标蛋白甾醇14α-脱甲基酶三维结构筛选的化合物及其在在制备杀菌剂中的应用
EP3886854A4 (en) 2018-11-30 2022-07-06 Nuvation Bio Inc. PYRROLE AND PYRAZOLE COMPOUNDS AND METHODS OF USE THERE
CN114258391A (zh) 2019-04-03 2022-03-29 阿里戈斯治疗公司 吡咯化合物
BR112022025918A2 (pt) 2020-06-18 2023-03-14 Akagera Medicines Inc Compostos de oxazolidinona, composições lipossomais que compreendem compostos de oxazolidinona e métodos de uso dos mesmos

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4801600A (en) 1987-10-09 1989-01-31 E. I. Du Pont De Nemours And Company Aminomethyl oxooxazolidinyl cycloalkylbenzene derivatives useful as antibacterial agents
US4921869A (en) 1987-10-09 1990-05-01 E. I. Du Pont De Nemours And Company Aminomethyl oxooxazolidinyl cycloalkylbenzene derivatives useful as antibacterial agents
CA1320730C (en) 1987-10-16 1993-07-27 The Du Pont Merck Pharmaceutical Company Aminomethyl oxooxazolidinyl aroylbenzene derivatives useful as antibacterial agents
US5254577A (en) 1988-07-29 1993-10-19 The Du Pont Merck Pharmaceutical Company Aminomethyloxooxazolidinyl arylbenzene derivatives useful as antibacterial agents
US4948801A (en) 1988-07-29 1990-08-14 E. I. Du Pont De Nemours And Company Aminomethyloxooxazolidinyl arylbenzene derivatives useful as antibacterial agents
DE68929303T2 (de) 1988-09-15 2002-05-02 Pharmacia & Upjohn Co., Kalamazoo 3-(Stickstoff substituierte)phenyl-5-beta-amidomethyloxazoliden-2-one
US5164402A (en) * 1989-08-16 1992-11-17 Pfizer Inc Azabicyclo quinolone and naphthyridinone carboxylic acids
CA2119556C (en) 1991-11-01 2004-07-06 Michael Robert Barbachyn Substituted aryl- and heteroaryl-phenyloxazolidinones
SK283420B6 (sk) * 1992-05-08 2003-07-01 Pharmacia & Upjohn Company Antimikrobiálne oxazolidinóny obsahujúce substituované diazínové skupiny
US5652238A (en) 1993-11-22 1997-07-29 Pharmacia & Upjohn Company Esters of substituted-hydroxyacetyl piperazine phenyl oxazolidinones
JPH0873455A (ja) * 1994-03-15 1996-03-19 Upjohn Co:The オキサゾリジノン誘導体及びこれを有効成分とする医薬組成物
JPH11512429A (ja) * 1995-09-15 1999-10-26 ファルマシア・アンド・アップジョン・カンパニー アミノアリールオキサゾリジノン ｎ−オキシド
GB9521508D0 (en) * 1995-10-20 1995-12-20 Zeneca Ltd Chemical compounds
GB9702213D0 (en) * 1996-02-24 1997-03-26 Zeneca Ltd Chemical compounds
MY116093A (en) * 1996-02-26 2003-11-28 Upjohn Co Azolyl piperazinyl phenyl oxazolidinone antimicrobials
GB9614238D0 (en) 1996-07-06 1996-09-04 Zeneca Ltd Chemical compounds
ATE293609T1 (de) * 1997-05-30 2005-05-15 Upjohn Co Antibakteriell wirksam oxazolidinone mit einer thiocarbonylfunktionalität
CA2351062A1 (en) * 1998-11-27 2000-06-08 Pharmacia & Upjohn Company Oxazolidinone antibacterial agents having a thiocarbonyl functionality
EP1303511A1 (en) 2000-07-17 2003-04-23 Ranbaxy Laboratories, Ltd. Oxazolidinone derivatives as antimicrobials

Also Published As

Publication number Publication date
AU6937001A (en) 2002-01-30
ZA200300471B (en) 2003-10-29
CA2415965A1 (en) 2002-01-24
RU2292345C2 (ru) 2007-01-27
BR0112826A (pt) 2003-06-24
US20040242591A1 (en) 2004-12-02
MXPA03000503A (es) 2003-10-14
JP2004504321A (ja) 2004-02-12
NZ523700A (en) 2004-11-26
US6734307B2 (en) 2004-05-11
CN1447808A (zh) 2003-10-08
HUP0302918A2 (hu) 2003-12-29
WO2002006278A1 (en) 2002-01-24
AU2001269370B2 (en) 2005-10-27
EP1303511A1 (en) 2003-04-23
RU2292345C9 (ru) 2007-05-10
PL363960A1 (en) 2004-11-29
US20020103186A1 (en) 2002-08-01
CZ2003228A3 (cs) 2003-06-18

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FC9A Refused patent application