SK122194A3 - Perhydroisoindole derivatives and preparation thereof - Google Patents

Perhydroisoindole derivatives and preparation thereof Download PDF

Info

Publication number
SK122194A3
SK122194A3 SK1221-94A SK122194A SK122194A3 SK 122194 A3 SK122194 A3 SK 122194A3 SK 122194 A SK122194 A SK 122194A SK 122194 A3 SK122194 A3 SK 122194A3
Authority
SK
Slovakia
Prior art keywords
group
diphenyl
methoxyphenyl
perhydroisoindole
hydroxy
Prior art date
Application number
SK1221-94A
Other languages
English (en)
Slovak (sk)
Inventor
Daniel Achard
Serge Grisoni
Jean-Luc Malleron
Jean-Francois Peyronel
Michel Tabart
Original Assignee
Rhone Poulenc Rorer Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Rorer Sa filed Critical Rhone Poulenc Rorer Sa
Publication of SK122194A3 publication Critical patent/SK122194A3/sk

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SK1221-94A 1992-04-10 1993-04-08 Perhydroisoindole derivatives and preparation thereof SK122194A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR929204391A FR2689889B1 (fr) 1992-04-10 1992-04-10 Nouveaux derives de perhydroisoindole, et leur preparation.
PCT/FR1993/000351 WO1993021154A1 (fr) 1992-04-10 1993-04-08 Nouveaux derives de perhydroisoindole, et leur preparation

Publications (1)

Publication Number Publication Date
SK122194A3 true SK122194A3 (en) 1995-05-10

Family

ID=9428708

Family Applications (1)

Application Number Title Priority Date Filing Date
SK1221-94A SK122194A3 (en) 1992-04-10 1993-04-08 Perhydroisoindole derivatives and preparation thereof

Country Status (23)

Country Link
US (1) US5463077A (de)
EP (1) EP0635002B1 (de)
JP (1) JPH07505409A (de)
KR (1) KR950700879A (de)
AT (1) ATE168674T1 (de)
AU (1) AU667365B2 (de)
CA (1) CA2133841A1 (de)
CZ (1) CZ284596B6 (de)
DE (1) DE69319902T2 (de)
DK (1) DK0635002T3 (de)
ES (1) ES2118954T3 (de)
FI (1) FI105022B (de)
FR (1) FR2689889B1 (de)
HU (1) HUT71330A (de)
IL (2) IL105256A (de)
MX (1) MX9301985A (de)
NO (1) NO300418B1 (de)
PL (1) PL172753B1 (de)
RU (1) RU2120438C1 (de)
SK (1) SK122194A3 (de)
TW (1) TW224969B (de)
WO (1) WO1993021154A1 (de)
ZA (1) ZA932528B (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2689888B1 (fr) * 1992-04-10 1994-06-10 Rhone Poulenc Rorer Sa Nouveaux derives de perhydroisoindole, leur preparation et les compositions pharmaceutiques qui les contiennent.
FR2703679B1 (fr) * 1993-04-05 1995-06-23 Rhone Poulenc Rorer Sa Nouveaux derives de perhydroisoindole, leur preparation et les compositions pharmaceutiques qui les contiennent.
TW365603B (en) * 1993-07-30 1999-08-01 Rhone Poulenc Rorer Sa Novel perhydroisoindole derivatives, their preparation and pharmaceutical compositions which contain them
FR2709752B1 (fr) * 1993-07-30 1995-10-06 Rhone Poulenc Rorer Sa Nouveaux dérivés de perhydroisoindole, leur préparation et les compositions pharmaceutiques qui les contiennent.
FR2710913B1 (fr) * 1993-10-07 1995-11-24 Rhone Poulenc Rorer Sa Nouveaux dérivés de perhydroisoindole, leur préparation et les compositions pharmaceutiques qui les contiennent.
CN100391945C (zh) * 2005-05-31 2008-06-04 浙江大学 一种s-(-)-吲哚啉-2-羧酸的合成方法
EP2729147B1 (de) 2011-07-04 2017-09-06 IRBM - Science Park S.p.A. Nk-1 rezeptorantagonisten zur behandlung der hornhautrevaskularisierung
JP2021514976A (ja) 2018-02-26 2021-06-17 オスペダーレ・サン・ラッファエーレ・エッセエッレエッレ 眼痛の治療における使用のためのｎｋ−１拮抗薬
EP4117673A1 (de) 2020-03-11 2023-01-18 Ospedale San Raffaele S.r.l. Behandlung von stammzellenmangel

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4042707A (en) * 1976-02-19 1977-08-16 E. I. Du Pont De Nemours And Company 3α-Arylhydroisoindoles
DE3617183A1 (de) * 1985-11-16 1987-05-27 Bayer Ag Substituierte benzylether
FR2654725B1 (fr) * 1989-11-23 1992-02-14 Rhone Poulenc Sante Nouveaux derives de l'isoindolone, leur preparation et les compositions pharmaceutiques qui les contiennent.
FR2654726B1 (fr) * 1989-11-23 1992-02-14 Rhone Poulenc Sante Nouveaux derives de l'isoindolone et leur preparation.
FR2676443B1 (fr) * 1991-05-17 1993-08-06 Rhone Poulenc Rorer Sa Nouveaux derives de perhydroisoindole et leur preparation.

Also Published As

Publication number Publication date
DE69319902T2 (de) 1999-03-18
IL105256A0 (en) 1993-08-18
CZ284596B6 (cs) 1999-01-13
PL172753B1 (en) 1997-11-28
KR950700879A (ko) 1995-02-20
FI944728A0 (fi) 1994-10-07
RU2120438C1 (ru) 1998-10-20
MX9301985A (es) 1994-05-31
NO300418B1 (no) 1997-05-26
AU667365B2 (en) 1996-03-21
AU3956493A (en) 1993-11-18
NO943738L (no) 1994-10-05
RU94045867A (ru) 1996-09-10
FI105022B (fi) 2000-05-31
IL105256A (en) 1997-08-14
FR2689889B1 (fr) 1994-06-10
ATE168674T1 (de) 1998-08-15
EP0635002B1 (de) 1998-07-22
CA2133841A1 (fr) 1993-10-28
WO1993021154A1 (fr) 1993-10-28
DE69319902D1 (de) 1998-08-27
EP0635002A1 (de) 1995-01-25
DK0635002T3 (da) 1999-02-22
JPH07505409A (ja) 1995-06-15
FR2689889A1 (fr) 1993-10-15
FI944728A (fi) 1994-10-07
NO943738D0 (no) 1994-10-05
US5463077A (en) 1995-10-31
ES2118954T3 (es) 1998-10-01
CZ248394A3 (en) 1995-11-15
HUT71330A (en) 1995-11-28
TW224969B (de) 1994-06-11
ZA932528B (en) 1993-10-28
HU9402912D0 (en) 1995-01-30

Similar Documents

Publication Publication Date Title
AU667214B2 (en) Perhydroisoindole derivatives as P substance antagonists
US5624950A (en) Perhydroisoindole derivatives as substance P antagonists
US5451601A (en) Perhydroisoindole derivatives and pharmaceutical compositions containing them
US5508433A (en) Derivatives of perhydroisoindole and preparation thereof
RU2012559C1 (ru) Производные изоиндолона в виде (3 аr, 7 аr)- или (3 аrs, 7 аrs)-форм или их смесей или их гидрохлориды, являющиеся антагонистами вещества р
US5739351A (en) Perhydroisoindole derivatives as substance P antagonists
SK126693A3 (en) Novel derivatives of thiopyranopyrrole and preparation thereof
CZ244993A3 (en) Novel thiopyrrole derivatives, process of their preparation and pharmaceutical preparations in which they are comprised
HU214574B (hu) Eljárás izoindolonszármazékok előállítására
SK122194A3 (en) Perhydroisoindole derivatives and preparation thereof
SK123595A3 (en) Perhydroisoindole derivatives, preparation thereof and pharmaceutical compositions containing same