SK119699A3 - Crystalline hydrated sodium salt of (e)-4,6-dichloro-3-(2-oxo- -1-phenylpyrrolidin-3-ylidene methyl)-1h-indole-2-carboxylic acid - Google Patents

Crystalline hydrated sodium salt of (e)-4,6-dichloro-3-(2-oxo- -1-phenylpyrrolidin-3-ylidene methyl)-1h-indole-2-carboxylic acid Download PDF

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Publication number
SK119699A3
SK119699A3 SK1196-99A SK119699A SK119699A3 SK 119699 A3 SK119699 A3 SK 119699A3 SK 119699 A SK119699 A SK 119699A SK 119699 A3 SK119699 A3 SK 119699A3
Authority
SK
Slovakia
Prior art keywords
crystalline hydrated
hydrated form
sodium salt
oxo
compound
Prior art date
Application number
SK1196-99A
Other languages
English (en)
Slovak (sk)
Inventor
Zadeo Cimarosti
Paolo Maragni
Original Assignee
Glaxo Wellcome Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Wellcome Spa filed Critical Glaxo Wellcome Spa
Publication of SK119699A3 publication Critical patent/SK119699A3/sk

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Neurosurgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Indole Compounds (AREA)
SK1196-99A 1997-03-05 1998-03-03 Crystalline hydrated sodium salt of (e)-4,6-dichloro-3-(2-oxo- -1-phenylpyrrolidin-3-ylidene methyl)-1h-indole-2-carboxylic acid SK119699A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9704498.6A GB9704498D0 (en) 1997-03-05 1997-03-05 Chemical compound
PCT/EP1998/001146 WO1998039327A1 (en) 1997-03-05 1998-03-03 Crystalline hydrated sodium salt of (e)-4,6-dichloro-3-(2-oxo-1-phenylpyrrolidin-3-ylidene methyl)-1h-indole-2-carboxylic acid

Publications (1)

Publication Number Publication Date
SK119699A3 true SK119699A3 (en) 2000-05-16

Family

ID=10808697

Family Applications (1)

Application Number Title Priority Date Filing Date
SK1196-99A SK119699A3 (en) 1997-03-05 1998-03-03 Crystalline hydrated sodium salt of (e)-4,6-dichloro-3-(2-oxo- -1-phenylpyrrolidin-3-ylidene methyl)-1h-indole-2-carboxylic acid

Country Status (29)

Country Link
EP (1) EP0966463A1 (xx)
JP (1) JP2001513796A (xx)
KR (1) KR20000075907A (xx)
CN (1) CN1249750A (xx)
AP (1) AP9901637A0 (xx)
AR (1) AR011178A1 (xx)
AU (1) AU6825198A (xx)
BG (1) BG103779A (xx)
BR (1) BR9808305A (xx)
CA (1) CA2282851A1 (xx)
CO (1) CO4940415A1 (xx)
EA (1) EA199900710A1 (xx)
EE (1) EE9900387A (xx)
GB (1) GB9704498D0 (xx)
HR (1) HRP980114A2 (xx)
HU (1) HUP0002109A2 (xx)
ID (1) ID24207A (xx)
IL (1) IL131489A0 (xx)
IS (1) IS5166A (xx)
NO (1) NO994303L (xx)
NZ (1) NZ337315A (xx)
OA (1) OA11154A (xx)
PE (1) PE51399A1 (xx)
PL (1) PL335652A1 (xx)
SK (1) SK119699A3 (xx)
TR (1) TR199902117T2 (xx)
WO (1) WO1998039327A1 (xx)
YU (1) YU43499A (xx)
ZA (1) ZA981791B (xx)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9704499D0 (en) * 1997-03-05 1997-04-23 Glaxo Wellcome Spa Method of manufacture
GB9825988D0 (en) 1998-11-27 1999-01-20 Pfizer Ltd Indole derivatives
GB9915231D0 (en) 1999-06-29 1999-09-01 Pfizer Ltd Pharmaceutical complex
US9737531B2 (en) 2012-07-12 2017-08-22 Glytech, Llc Composition and method for treatment of depression and psychosis in humans
RU2020100230A (ru) 2017-06-12 2021-07-13 Глитек Ллс. Лечение депрессии антагонистами nmda и антагонистами d2/5-ht2a или селективными антагонистами 5-нт2a

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9321221D0 (en) * 1993-10-14 1993-12-01 Glaxo Spa Heterocyclic compounds

Also Published As

Publication number Publication date
PE51399A1 (es) 1999-06-07
IL131489A0 (en) 2001-01-28
NO994303L (no) 1999-11-03
EA199900710A1 (ru) 2000-04-24
BR9808305A (pt) 2000-05-16
EE9900387A (et) 2000-04-17
ID24207A (id) 2000-07-13
HUP0002109A2 (hu) 2001-04-28
IS5166A (is) 1999-08-27
PL335652A1 (en) 2000-05-08
TR199902117T2 (xx) 2000-03-21
AU6825198A (en) 1998-09-22
OA11154A (en) 2003-04-16
CN1249750A (zh) 2000-04-05
NZ337315A (en) 2001-02-23
BG103779A (en) 2000-06-30
HRP980114A2 (en) 1998-12-31
JP2001513796A (ja) 2001-09-04
KR20000075907A (ko) 2000-12-26
EP0966463A1 (en) 1999-12-29
NO994303D0 (no) 1999-09-03
GB9704498D0 (en) 1997-04-23
CO4940415A1 (es) 2000-07-24
AP9901637A0 (en) 1999-09-30
ZA981791B (en) 1999-09-03
CA2282851A1 (en) 1998-09-11
WO1998039327A1 (en) 1998-09-11
AR011178A1 (es) 2000-08-02
YU43499A (sh) 2000-12-28

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