PE51399A1 - Forma hidratada cristalina de la sal de sodio del acido (e)-4,6-dicloro-3-(2-oxo-1-fenilpirrolidin-3-ilideno-metil)-1h-indol-2-carboxilico - Google Patents
Forma hidratada cristalina de la sal de sodio del acido (e)-4,6-dicloro-3-(2-oxo-1-fenilpirrolidin-3-ilideno-metil)-1h-indol-2-carboxilicoInfo
- Publication number
- PE51399A1 PE51399A1 PE1998000149A PE00014998A PE51399A1 PE 51399 A1 PE51399 A1 PE 51399A1 PE 1998000149 A PE1998000149 A PE 1998000149A PE 00014998 A PE00014998 A PE 00014998A PE 51399 A1 PE51399 A1 PE 51399A1
- Authority
- PE
- Peru
- Prior art keywords
- methyl
- ilideno
- fenilpirrolidin
- carboxilico
- indol
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Neurology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Neurosurgery (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Indole Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
CARACTERIZADA PORQUE EL CONTENIDO DE AGUA ES ENTRE 2,5% A 3,1% EN PESO; ASI COMO POR SU ESPECTRO INFRAROJO Y POR SU PATRON DE DIFRACCION DE RAYOS X . TAMBIEN SE REFIERE AL PROCESO PARA SU PREPARACION QUE COMPRENDE LA HIDROLISIS DEL ESTER DE ALQUILO POR REACCION CON NaOH ACUOSO EN PRESENCIA DE UN ALCOHOL SEGUIDO POR LA ADICION DE AGUA. ESTE COMPUESTO ANTAGONIZA LOS EFECTOS DE LOS AMINOACIDOS EXCITATORIOS SOBRE EL COMPLEJO RECEPTOR N-METIL-D-ASPARTATO (NMDA), POR LO QUE PUEDE SER UTIL EN EL TRATAMIENTO DE PREVENCION DE DANOS NEUROTOXICOS Y ENFERMEDADES NEURODEGENERATIVAS
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9704498.6A GB9704498D0 (en) | 1997-03-05 | 1997-03-05 | Chemical compound |
Publications (1)
Publication Number | Publication Date |
---|---|
PE51399A1 true PE51399A1 (es) | 1999-06-07 |
Family
ID=10808697
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PE1998000149A PE51399A1 (es) | 1997-03-05 | 1998-03-03 | Forma hidratada cristalina de la sal de sodio del acido (e)-4,6-dicloro-3-(2-oxo-1-fenilpirrolidin-3-ilideno-metil)-1h-indol-2-carboxilico |
Country Status (29)
Country | Link |
---|---|
EP (1) | EP0966463A1 (es) |
JP (1) | JP2001513796A (es) |
KR (1) | KR20000075907A (es) |
CN (1) | CN1249750A (es) |
AP (1) | AP9901637A0 (es) |
AR (1) | AR011178A1 (es) |
AU (1) | AU6825198A (es) |
BG (1) | BG103779A (es) |
BR (1) | BR9808305A (es) |
CA (1) | CA2282851A1 (es) |
CO (1) | CO4940415A1 (es) |
EA (1) | EA199900710A1 (es) |
EE (1) | EE9900387A (es) |
GB (1) | GB9704498D0 (es) |
HR (1) | HRP980114A2 (es) |
HU (1) | HUP0002109A2 (es) |
ID (1) | ID24207A (es) |
IL (1) | IL131489A0 (es) |
IS (1) | IS5166A (es) |
NO (1) | NO994303L (es) |
NZ (1) | NZ337315A (es) |
OA (1) | OA11154A (es) |
PE (1) | PE51399A1 (es) |
PL (1) | PL335652A1 (es) |
SK (1) | SK119699A3 (es) |
TR (1) | TR199902117T2 (es) |
WO (1) | WO1998039327A1 (es) |
YU (1) | YU43499A (es) |
ZA (1) | ZA981791B (es) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9704499D0 (en) * | 1997-03-05 | 1997-04-23 | Glaxo Wellcome Spa | Method of manufacture |
GB9825988D0 (en) * | 1998-11-27 | 1999-01-20 | Pfizer Ltd | Indole derivatives |
GB9915231D0 (en) | 1999-06-29 | 1999-09-01 | Pfizer Ltd | Pharmaceutical complex |
US9737531B2 (en) | 2012-07-12 | 2017-08-22 | Glytech, Llc | Composition and method for treatment of depression and psychosis in humans |
AU2018284335A1 (en) | 2017-06-12 | 2020-01-30 | Glytech Llc. | Treatment of depression with NMDA antagonists and D2/5HT2A or selective 5HT2A antagonists |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9321221D0 (en) * | 1993-10-14 | 1993-12-01 | Glaxo Spa | Heterocyclic compounds |
-
1997
- 1997-03-05 GB GBGB9704498.6A patent/GB9704498D0/en active Pending
-
1998
- 1998-03-03 PL PL98335652A patent/PL335652A1/xx unknown
- 1998-03-03 AU AU68251/98A patent/AU6825198A/en not_active Abandoned
- 1998-03-03 CN CN98803053A patent/CN1249750A/zh active Pending
- 1998-03-03 WO PCT/EP1998/001146 patent/WO1998039327A1/en not_active Application Discontinuation
- 1998-03-03 IL IL13148998A patent/IL131489A0/xx unknown
- 1998-03-03 AP APAP/P/1999/001637A patent/AP9901637A0/en unknown
- 1998-03-03 JP JP53813598A patent/JP2001513796A/ja active Pending
- 1998-03-03 KR KR1019997007987A patent/KR20000075907A/ko not_active Application Discontinuation
- 1998-03-03 NZ NZ337315A patent/NZ337315A/en unknown
- 1998-03-03 SK SK1196-99A patent/SK119699A3/sk unknown
- 1998-03-03 PE PE1998000149A patent/PE51399A1/es not_active Application Discontinuation
- 1998-03-03 EA EA199900710A patent/EA199900710A1/ru unknown
- 1998-03-03 BR BR9808305-8A patent/BR9808305A/pt not_active Application Discontinuation
- 1998-03-03 EE EEP199900387A patent/EE9900387A/xx unknown
- 1998-03-03 ZA ZA9801791A patent/ZA981791B/xx unknown
- 1998-03-03 TR TR1999/02117T patent/TR199902117T2/xx unknown
- 1998-03-03 HU HU0002109A patent/HUP0002109A2/hu unknown
- 1998-03-03 CA CA002282851A patent/CA2282851A1/en not_active Abandoned
- 1998-03-03 ID IDW990976A patent/ID24207A/id unknown
- 1998-03-03 YU YU43499A patent/YU43499A/sh unknown
- 1998-03-03 EP EP98913613A patent/EP0966463A1/en not_active Withdrawn
- 1998-03-03 CO CO98011404A patent/CO4940415A1/es unknown
- 1998-03-03 AR ARP980100948A patent/AR011178A1/es unknown
- 1998-03-04 HR HR9704498.6A patent/HRP980114A2/hr not_active Application Discontinuation
-
1999
- 1999-08-27 IS IS5166A patent/IS5166A/is unknown
- 1999-09-02 OA OA9900201A patent/OA11154A/fr unknown
- 1999-09-03 NO NO994303A patent/NO994303L/no not_active Application Discontinuation
- 1999-10-04 BG BG103779A patent/BG103779A/xx unknown
Also Published As
Publication number | Publication date |
---|---|
ZA981791B (en) | 1999-09-03 |
AP9901637A0 (en) | 1999-09-30 |
HUP0002109A2 (hu) | 2001-04-28 |
OA11154A (en) | 2003-04-16 |
CO4940415A1 (es) | 2000-07-24 |
CN1249750A (zh) | 2000-04-05 |
EA199900710A1 (ru) | 2000-04-24 |
YU43499A (sh) | 2000-12-28 |
NO994303D0 (no) | 1999-09-03 |
NZ337315A (en) | 2001-02-23 |
BG103779A (en) | 2000-06-30 |
HRP980114A2 (en) | 1998-12-31 |
CA2282851A1 (en) | 1998-09-11 |
EP0966463A1 (en) | 1999-12-29 |
SK119699A3 (en) | 2000-05-16 |
WO1998039327A1 (en) | 1998-09-11 |
TR199902117T2 (xx) | 2000-03-21 |
PL335652A1 (en) | 2000-05-08 |
AR011178A1 (es) | 2000-08-02 |
AU6825198A (en) | 1998-09-22 |
IS5166A (is) | 1999-08-27 |
JP2001513796A (ja) | 2001-09-04 |
KR20000075907A (ko) | 2000-12-26 |
ID24207A (id) | 2000-07-13 |
GB9704498D0 (en) | 1997-04-23 |
IL131489A0 (en) | 2001-01-28 |
NO994303L (no) | 1999-11-03 |
BR9808305A (pt) | 2000-05-16 |
EE9900387A (et) | 2000-04-17 |
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