CA2282851A1 - Crystalline hydrated sodium salt of (e)-4,6-dichloro-3-(2-oxo-1-phenylpyrrolidin-3-ylidene methyl)-1h-indole-2-carboxylic acid - Google Patents
Crystalline hydrated sodium salt of (e)-4,6-dichloro-3-(2-oxo-1-phenylpyrrolidin-3-ylidene methyl)-1h-indole-2-carboxylic acid Download PDFInfo
- Publication number
- CA2282851A1 CA2282851A1 CA002282851A CA2282851A CA2282851A1 CA 2282851 A1 CA2282851 A1 CA 2282851A1 CA 002282851 A CA002282851 A CA 002282851A CA 2282851 A CA2282851 A CA 2282851A CA 2282851 A1 CA2282851 A1 CA 2282851A1
- Authority
- CA
- Canada
- Prior art keywords
- compound
- crystalline hydrated
- sodium salt
- hydrated form
- theta
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Neurology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Neurosurgery (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB9704498.6 | 1997-03-05 | ||
| GBGB9704498.6A GB9704498D0 (en) | 1997-03-05 | 1997-03-05 | Chemical compound |
| PCT/EP1998/001146 WO1998039327A1 (en) | 1997-03-05 | 1998-03-03 | Crystalline hydrated sodium salt of (e)-4,6-dichloro-3-(2-oxo-1-phenylpyrrolidin-3-ylidene methyl)-1h-indole-2-carboxylic acid |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2282851A1 true CA2282851A1 (en) | 1998-09-11 |
Family
ID=10808697
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002282851A Abandoned CA2282851A1 (en) | 1997-03-05 | 1998-03-03 | Crystalline hydrated sodium salt of (e)-4,6-dichloro-3-(2-oxo-1-phenylpyrrolidin-3-ylidene methyl)-1h-indole-2-carboxylic acid |
Country Status (29)
| Country | Link |
|---|---|
| EP (1) | EP0966463A1 (xx) |
| JP (1) | JP2001513796A (xx) |
| KR (1) | KR20000075907A (xx) |
| CN (1) | CN1249750A (xx) |
| AP (1) | AP9901637A0 (xx) |
| AR (1) | AR011178A1 (xx) |
| AU (1) | AU6825198A (xx) |
| BG (1) | BG103779A (xx) |
| BR (1) | BR9808305A (xx) |
| CA (1) | CA2282851A1 (xx) |
| CO (1) | CO4940415A1 (xx) |
| EA (1) | EA199900710A1 (xx) |
| EE (1) | EE9900387A (xx) |
| GB (1) | GB9704498D0 (xx) |
| HR (1) | HRP980114A2 (xx) |
| HU (1) | HUP0002109A2 (xx) |
| ID (1) | ID24207A (xx) |
| IL (1) | IL131489A0 (xx) |
| IS (1) | IS5166A (xx) |
| NO (1) | NO994303L (xx) |
| NZ (1) | NZ337315A (xx) |
| OA (1) | OA11154A (xx) |
| PE (1) | PE51399A1 (xx) |
| PL (1) | PL335652A1 (xx) |
| SK (1) | SK119699A3 (xx) |
| TR (1) | TR199902117T2 (xx) |
| WO (1) | WO1998039327A1 (xx) |
| YU (1) | YU43499A (xx) |
| ZA (1) | ZA981791B (xx) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9704499D0 (en) * | 1997-03-05 | 1997-04-23 | Glaxo Wellcome Spa | Method of manufacture |
| GB9825988D0 (en) | 1998-11-27 | 1999-01-20 | Pfizer Ltd | Indole derivatives |
| GB9915231D0 (en) | 1999-06-29 | 1999-09-01 | Pfizer Ltd | Pharmaceutical complex |
| US9737531B2 (en) | 2012-07-12 | 2017-08-22 | Glytech, Llc | Composition and method for treatment of depression and psychosis in humans |
| RU2020100230A (ru) | 2017-06-12 | 2021-07-13 | Глитек Ллс. | Лечение депрессии антагонистами nmda и антагонистами d2/5-ht2a или селективными антагонистами 5-нт2a |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9321221D0 (en) * | 1993-10-14 | 1993-12-01 | Glaxo Spa | Heterocyclic compounds |
-
1997
- 1997-03-05 GB GBGB9704498.6A patent/GB9704498D0/en active Pending
-
1998
- 1998-03-03 AR ARP980100948A patent/AR011178A1/es unknown
- 1998-03-03 ZA ZA9801791A patent/ZA981791B/xx unknown
- 1998-03-03 WO PCT/EP1998/001146 patent/WO1998039327A1/en not_active Application Discontinuation
- 1998-03-03 HU HU0002109A patent/HUP0002109A2/hu unknown
- 1998-03-03 TR TR1999/02117T patent/TR199902117T2/xx unknown
- 1998-03-03 AP APAP/P/1999/001637A patent/AP9901637A0/en unknown
- 1998-03-03 EP EP98913613A patent/EP0966463A1/en not_active Withdrawn
- 1998-03-03 YU YU43499A patent/YU43499A/sh unknown
- 1998-03-03 BR BR9808305-8A patent/BR9808305A/pt not_active Application Discontinuation
- 1998-03-03 CO CO98011404A patent/CO4940415A1/es unknown
- 1998-03-03 ID IDW990976A patent/ID24207A/id unknown
- 1998-03-03 AU AU68251/98A patent/AU6825198A/en not_active Abandoned
- 1998-03-03 PE PE1998000149A patent/PE51399A1/es not_active Application Discontinuation
- 1998-03-03 EA EA199900710A patent/EA199900710A1/ru unknown
- 1998-03-03 PL PL98335652A patent/PL335652A1/xx unknown
- 1998-03-03 IL IL13148998A patent/IL131489A0/xx unknown
- 1998-03-03 JP JP53813598A patent/JP2001513796A/ja active Pending
- 1998-03-03 KR KR1019997007987A patent/KR20000075907A/ko not_active Application Discontinuation
- 1998-03-03 EE EEP199900387A patent/EE9900387A/xx unknown
- 1998-03-03 NZ NZ337315A patent/NZ337315A/en unknown
- 1998-03-03 SK SK1196-99A patent/SK119699A3/sk unknown
- 1998-03-03 CA CA002282851A patent/CA2282851A1/en not_active Abandoned
- 1998-03-03 CN CN98803053A patent/CN1249750A/zh active Pending
- 1998-03-04 HR HR9704498.6A patent/HRP980114A2/hr not_active Application Discontinuation
-
1999
- 1999-08-27 IS IS5166A patent/IS5166A/is unknown
- 1999-09-02 OA OA9900201A patent/OA11154A/fr unknown
- 1999-09-03 NO NO994303A patent/NO994303L/no not_active Application Discontinuation
- 1999-10-04 BG BG103779A patent/BG103779A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PE51399A1 (es) | 1999-06-07 |
| IL131489A0 (en) | 2001-01-28 |
| NO994303L (no) | 1999-11-03 |
| EA199900710A1 (ru) | 2000-04-24 |
| BR9808305A (pt) | 2000-05-16 |
| EE9900387A (et) | 2000-04-17 |
| ID24207A (id) | 2000-07-13 |
| HUP0002109A2 (hu) | 2001-04-28 |
| SK119699A3 (en) | 2000-05-16 |
| IS5166A (is) | 1999-08-27 |
| PL335652A1 (en) | 2000-05-08 |
| TR199902117T2 (xx) | 2000-03-21 |
| AU6825198A (en) | 1998-09-22 |
| OA11154A (en) | 2003-04-16 |
| CN1249750A (zh) | 2000-04-05 |
| NZ337315A (en) | 2001-02-23 |
| BG103779A (en) | 2000-06-30 |
| HRP980114A2 (en) | 1998-12-31 |
| JP2001513796A (ja) | 2001-09-04 |
| KR20000075907A (ko) | 2000-12-26 |
| EP0966463A1 (en) | 1999-12-29 |
| NO994303D0 (no) | 1999-09-03 |
| GB9704498D0 (en) | 1997-04-23 |
| CO4940415A1 (es) | 2000-07-24 |
| AP9901637A0 (en) | 1999-09-30 |
| ZA981791B (en) | 1999-09-03 |
| WO1998039327A1 (en) | 1998-09-11 |
| AR011178A1 (es) | 2000-08-02 |
| YU43499A (sh) | 2000-12-28 |
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| CA2282851A1 (en) | Crystalline hydrated sodium salt of (e)-4,6-dichloro-3-(2-oxo-1-phenylpyrrolidin-3-ylidene methyl)-1h-indole-2-carboxylic acid | |
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| CZ314799A3 (cs) | Krystalická hydratovaná sodná sůl kyseliny (E)-4,6-dichlor-3-(2-oxo-l-fenylpyrrolidin-3- ylidenmethyl)-lH-indol-2-karboxylové |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Discontinued |