SI9111508B - Recombinant DNA and RNA and products derived therefrom - Google Patents
Recombinant DNA and RNA and products derived therefrom Download PDFInfo
- Publication number
- SI9111508B SI9111508B SI9111508A SI9111508A SI9111508B SI 9111508 B SI9111508 B SI 9111508B SI 9111508 A SI9111508 A SI 9111508A SI 9111508 A SI9111508 A SI 9111508A SI 9111508 B SI9111508 B SI 9111508B
- Authority
- SI
- Slovenia
- Prior art keywords
- cav
- nucleotide sequence
- nucleic acid
- recombinant nucleic
- specific
- Prior art date
Links
- 108020004511 Recombinant DNA Proteins 0.000 title 1
- 241000725585 Chicken anemia virus Species 0.000 claims abstract 19
- 239000002773 nucleotide Substances 0.000 claims abstract 13
- 125000003729 nucleotide group Chemical group 0.000 claims abstract 13
- 108090000623 proteins and genes Proteins 0.000 claims abstract 5
- 102000004169 proteins and genes Human genes 0.000 claims abstract 5
- 108020004707 nucleic acids Proteins 0.000 claims 11
- 102000039446 nucleic acids Human genes 0.000 claims 11
- 150000007523 nucleic acids Chemical class 0.000 claims 11
- 238000000034 method Methods 0.000 claims 4
- 108020004414 DNA Proteins 0.000 claims 3
- 210000004027 cell Anatomy 0.000 claims 3
- 239000000523 sample Substances 0.000 claims 3
- 230000000295 complement effect Effects 0.000 claims 2
- 238000001514 detection method Methods 0.000 claims 2
- 229920000936 Agarose Polymers 0.000 claims 1
- CPELXLSAUQHCOX-UHFFFAOYSA-M Bromide Chemical compound [Br-] CPELXLSAUQHCOX-UHFFFAOYSA-M 0.000 claims 1
- 102000053602 DNA Human genes 0.000 claims 1
- 238000007399 DNA isolation Methods 0.000 claims 1
- 238000009007 Diagnostic Kit Methods 0.000 claims 1
- 108090000790 Enzymes Proteins 0.000 claims 1
- 102000004190 Enzymes Human genes 0.000 claims 1
- 101150061458 cav gene Proteins 0.000 claims 1
- 239000000975 dye Substances 0.000 claims 1
- 238000009585 enzyme analysis Methods 0.000 claims 1
- 210000003527 eukaryotic cell Anatomy 0.000 claims 1
- 230000002550 fecal effect Effects 0.000 claims 1
- 238000002372 labelling Methods 0.000 claims 1
- 239000000049 pigment Substances 0.000 claims 1
- 210000001236 prokaryotic cell Anatomy 0.000 claims 1
- -1 radioisotopes Chemical class 0.000 claims 1
- 230000009711 regulatory function Effects 0.000 claims 1
- 108091008146 restriction endonucleases Proteins 0.000 claims 1
- 239000000126 substance Substances 0.000 claims 1
- 238000002255 vaccination Methods 0.000 abstract 2
- 230000002068 genetic effect Effects 0.000 abstract 1
- 230000014616 translation Effects 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56983—Viruses
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
- C12N2750/00011—Details
- C12N2750/10011—Circoviridae
- C12N2750/10022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
- C12N2750/00011—Details
- C12N2750/10011—Circoviridae
- C12N2750/10041—Use of virus, viral particle or viral elements as a vector
- C12N2750/10043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/008—Vector systems having a special element relevant for transcription cell type or tissue specific enhancer/promoter combination
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/60—Vector systems having a special element relevant for transcription from viruses
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S424/00—Drug, bio-affecting and body treating compositions
- Y10S424/816—Viral vaccine for avian species, e.g. poultry or other birds
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/81—Packaged device or kit
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Virology (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Zoology (AREA)
- General Physics & Mathematics (AREA)
- Wood Science & Technology (AREA)
- Analytical Chemistry (AREA)
- Food Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pathology (AREA)
- Cell Biology (AREA)
- General Engineering & Computer Science (AREA)
- Oncology (AREA)
- Hospice & Palliative Care (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Plant Pathology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Public Health (AREA)
- Communicable Diseases (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
Claims (11)
1 Patentni zahtevki 1. Postopek za proizvodnjo virusa piščančje anemije v dvojnoverižni obliki, ki obsega stopnje izolacijo DNA z nizko molekulsko maso iz celic, inficiranih s CA V, frakcioniranje omenjene DNA z nizko molekulsko maso na agarozi/etidijevem bromidu, primerjanje omenjenega ffakcionimega vzorca s frakcionirnim vzorcem enake, a ne inficirane celice, izolacijo DNA, prisotne le v inficirani celici, in preverjanje, ali je ta DNA dvojnoverižna, z restrikcijsko encimsko analizo.
2. Rekombinantna nukleinska kislina v obliki dvojnoverižne DNA molekule, ki obsega nukleotidno sekvenco, specifično za virus piščančje anemije (CAV), ki se ujema z nukleotidno sekvenco genoma CAV ali njegovega dela, katero se da pridobiti s postopkom po zahtevku 1.
3. Rekombinantna nukleinska kislina, ki obsega nukleotidno sekvenco, specifično za CAV, ki se ujema ali je komplementarna z vsaj za CAV specifičnim delom nukleotidne sekvence, kije prikazana s SEQ. ID NO: 1, nukleotidno sekvenco, ki je z njo najmanj 60 %-no homologna, katero se da pridobiti s postopkom po zahtevku 1.
4. Rekombinantna nukleinska kislina po zahtevku 2 ali 3, ki obsega nukleotidno sekvenco, specifično za CAV, ki se ujema ali je komplementarna z nukleotidno sekvenco, ki obstaja v genomu CAV, pri čemer omenjena nukleotidna sekvenca kodira za vsaj del proteina CAV.
5. Rekombinantna nukleinska kislina po zahtevkih 2-4, ki nadalje obsega nukleotidno sekvenco, izvedeno iz prokariotičnega ali evkariotičnega vektorja.
6. Rekombinantna nukleinska kislina po zahtevkih 2-5, ki nadalje obsega nukleotidno sekvenco, ki kodira za protein, različen od proteina CAV, ali nukleotidno sekvenco, ki kodira za del takšnega različnega proteina. 2
7. Rekombinantna nukleinska kislina po zahtevkih 2-6, ki obsega nukleotidno sekvenco, ki ne obstaja v genomu CAV in ki ima regulatomo funkcijo.
8. Rekombinantna nukleinska kislina po kateremkoli od predhodnih zahtevkov 3-7, označena z enim ali več markerji, primernimi za označevanje nukleinskih kislin, kot so radioizotopi, encimske molekule, hapteni, fluorescentne snovi, barvila, pigmenti in markerji v obliki delcev.
9. Uporaba rekombinantne nukleinske kisline po kateremkoli od zahtevkov 2 ali 3 kot za CAV-specifične sonde ali za CAV-specifičnega primerja v postopku detekcije CAV-DNA ali -RNA.
10. Diagnostični komplet za detekcijo CAV-DNA ali -RNA, ki vsebuje rekombinantno nukleinsko kislino po zahtevkih 2-3 kot za CAV-specifično sondo ali za CAV-specifični primer.
11. Prokariotična ali evkariotična celica, ki vsebuje rekombinantno nukleinsko kislino po kateremkoli od zahtevkov 2-9.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NL9002008A NL9002008A (nl) | 1990-09-12 | 1990-09-12 | Recombinant dna en rna en daarvan afgeleide produkten. |
| YU150891A YU49095B (sh) | 1990-09-12 | 1991-09-11 | Rekombinantna dnk i rnk i proizvodi dobijeni od njih |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| SI9111508A SI9111508A (sl) | 1998-10-31 |
| SI9111508B true SI9111508B (en) | 2001-12-31 |
Family
ID=19857669
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SI9111508A SI9111508B (en) | 1990-09-12 | 1991-09-11 | Recombinant DNA and RNA and products derived therefrom |
Country Status (21)
| Country | Link |
|---|---|
| US (6) | US5491073A (sl) |
| EP (2) | EP0548234B1 (sl) |
| JP (1) | JP2846116B2 (sl) |
| AT (1) | ATE188739T1 (sl) |
| AU (1) | AU651999B2 (sl) |
| CA (1) | CA2091181C (sl) |
| DE (1) | DE69131903T2 (sl) |
| DK (1) | DK0548234T3 (sl) |
| ES (1) | ES2144399T3 (sl) |
| GR (1) | GR3033173T3 (sl) |
| HR (1) | HRP940668B1 (sl) |
| HU (1) | HU220102B (sl) |
| IL (1) | IL99435A (sl) |
| MX (1) | MX9101042A (sl) |
| NL (1) | NL9002008A (sl) |
| RU (1) | RU2146292C1 (sl) |
| SI (1) | SI9111508B (sl) |
| UA (1) | UA48936C2 (sl) |
| WO (1) | WO1992004446A1 (sl) |
| YU (1) | YU49095B (sl) |
| ZA (1) | ZA917065B (sl) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20080234466A1 (en) * | 1990-09-12 | 2008-09-25 | Noteborn Mathieu H M | Delivery method for the tumor-specific apoptosis-inducing activity of apoptin |
| NL9301272A (nl) * | 1993-07-20 | 1995-02-16 | Aesculaap Bv | Chicken Anemia Virus mutanten en vaccins en toepassingen gebaseerd op de virale eiwitten VP1, VP2 en VP3 of daarvoor coderende sequenties van dat virus. |
| US20020061296A1 (en) * | 2000-09-08 | 2002-05-23 | Noteborn Mathieu H.M. | Delivery method for the tumor specific apoptosis inducing activity of apoptin |
| US20030138443A1 (en) * | 1993-03-08 | 2003-07-24 | Noteborn Mathews H.M. | Cloning of chicken anemia virus DNA |
| US6162461A (en) * | 1990-09-12 | 2000-12-19 | Leadd B.V. | Chicken anemia virus mutants and vaccines and uses based on the viral proteins VP1, VP2 and VP3 or sequences of that virus coding therefor |
| ZA918426B (en) * | 1990-10-31 | 1992-12-30 | Akzo Nv | Chicken anemia virus vaccine and diagnostic |
| EP0878546A1 (en) * | 1997-04-15 | 1998-11-18 | Leadd B.V. | A gene delivery vehicle expressing the apoptosis-inducing proteins VP2 and/or apoptin |
| US5789567A (en) * | 1994-07-06 | 1998-08-04 | Cornell Research Foundation, Inc. | Chicken infectious anemia virus vaccine |
| GB9414888D0 (en) * | 1994-07-23 | 1994-09-14 | Univ Belfast | Method and composition |
| CA2221570A1 (en) * | 1995-06-07 | 1996-12-19 | Aesculaap B.V. | Neutralizing conformation epitopes of chicken anemia virus |
| CA2231729A1 (en) * | 1995-11-14 | 1997-05-22 | William L. Ragland | Efficient method of detecting an infectious agent in blood |
| EP1004021B1 (en) | 1997-08-12 | 2004-11-24 | Leadd B.V. | Determining the transforming capability of agents |
| WO1999045956A1 (en) * | 1998-03-13 | 1999-09-16 | University Of Georgia Research Foundation, Inc. | Vaccines against circovirus infections |
| DE60032201T2 (de) * | 1999-09-02 | 2007-09-20 | Leadd B.V. | Apoptin bindendes Protein |
| JP2003516152A (ja) * | 1999-12-10 | 2003-05-13 | レアト ベー．フェー． | アポプチン会合タンパク質 |
| US6593134B1 (en) | 2000-03-10 | 2003-07-15 | Cornell Research Foundation, Inc. | Method of propagating chicken infectious anemia virus |
| BR0106947B1 (pt) * | 2000-07-10 | 2009-05-05 | artigo de limpeza. | |
| EP1199363A1 (en) * | 2000-10-20 | 2002-04-24 | Leadd B.V. | Phosphorylation modifications of apoptin |
| BR0212279A (pt) * | 2001-09-05 | 2004-10-13 | Biomune | Vacina obtida de linhagem celular para vìrus causador de anemia em galinhas |
| US7566548B2 (en) * | 2004-08-13 | 2009-07-28 | University Of Massachusetts | Methods for identifying therapeutic agents and for treating disease |
| CN102636646A (zh) * | 2012-05-15 | 2012-08-15 | 扬州大学 | 快速检测禽白血病抗原的试纸条及其制备方法 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2042888B (en) | 1979-03-05 | 1983-09-28 | Teijin Ltd | Preparation for administration to the mucosa of the oral or nasal cavity |
| JPS6034925B2 (ja) | 1979-07-31 | 1985-08-12 | 帝人株式会社 | 持続性鼻腔用製剤およびその製造法 |
| JPS6032714A (ja) | 1983-08-01 | 1985-02-19 | Teijin Ltd | 鼻腔粘膜に適用するための安定化された粉末状薬学的組成物 |
| DE3583799D1 (de) | 1985-01-11 | 1991-09-19 | Abbott Lab Ltd | Feste zubereitung mit langsamer freisetzung. |
| US4683195A (en) * | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
| US5059587A (en) | 1987-08-03 | 1991-10-22 | Toyo Jozo Company, Ltd. | Physiologically active peptide composition for nasal administration |
| GB8723846D0 (en) | 1987-10-10 | 1987-11-11 | Danbiosyst Ltd | Bioadhesive microsphere drug delivery system |
| US5079005A (en) | 1988-06-17 | 1992-01-07 | Gupta Kashmiri L | Time release protein |
| EP0434747B1 (en) * | 1988-09-13 | 1999-05-19 | Merial | RECOMBINANT VACCINES BASED ON THE gB-PROTEIN OF MAREK'S DISEASE VIRUS |
| GB2237510B (en) | 1989-11-04 | 1993-09-15 | Danbiosyst Uk | Small particle drug compositions for nasal administration |
| US5271961A (en) | 1989-11-06 | 1993-12-21 | Alkermes Controlled Therapeutics, Inc. | Method for producing protein microspheres |
| ZA918426B (en) | 1990-10-31 | 1992-12-30 | Akzo Nv | Chicken anemia virus vaccine and diagnostic |
-
1990
- 1990-09-12 NL NL9002008A patent/NL9002008A/nl not_active Application Discontinuation
-
1991
- 1991-09-05 ZA ZA917065A patent/ZA917065B/xx unknown
- 1991-09-06 IL IL99435A patent/IL99435A/en not_active IP Right Cessation
- 1991-09-11 MX MX9101042A patent/MX9101042A/es unknown
- 1991-09-11 US US08/030,335 patent/US5491073A/en not_active Expired - Lifetime
- 1991-09-11 EP EP91917088A patent/EP0548234B1/en not_active Expired - Lifetime
- 1991-09-11 HU HU9300716A patent/HU220102B/hu not_active IP Right Cessation
- 1991-09-11 CA CA002091181A patent/CA2091181C/en not_active Expired - Lifetime
- 1991-09-11 WO PCT/NL1991/000165 patent/WO1992004446A1/en active IP Right Grant
- 1991-09-11 UA UA93004515A patent/UA48936C2/uk unknown
- 1991-09-11 AU AU86580/91A patent/AU651999B2/en not_active Ceased
- 1991-09-11 YU YU150891A patent/YU49095B/sh unknown
- 1991-09-11 JP JP3517451A patent/JP2846116B2/ja not_active Expired - Fee Related
- 1991-09-11 EP EP98202968A patent/EP0905246A1/en not_active Withdrawn
- 1991-09-11 ES ES91917088T patent/ES2144399T3/es not_active Expired - Lifetime
- 1991-09-11 RU RU93005170A patent/RU2146292C1/ru not_active IP Right Cessation
- 1991-09-11 AT AT91917088T patent/ATE188739T1/de not_active IP Right Cessation
- 1991-09-11 SI SI9111508A patent/SI9111508B/sl unknown
- 1991-09-11 DE DE69131903T patent/DE69131903T2/de not_active Expired - Lifetime
- 1991-09-11 DK DK91917088T patent/DK0548234T3/da active
-
1994
- 1994-10-12 HR HR940668A patent/HRP940668B1/xx not_active IP Right Cessation
-
1995
- 1995-06-07 US US08/480,020 patent/US5932476A/en not_active Expired - Fee Related
- 1995-06-07 US US08/484,939 patent/US6319693B1/en not_active Expired - Fee Related
-
1997
- 1997-08-13 US US08/910,322 patent/US6238669B1/en not_active Expired - Fee Related
- 1997-08-13 US US08/910,618 patent/US5958424A/en not_active Expired - Fee Related
-
1999
- 1999-08-27 US US09/384,472 patent/US6509446B2/en not_active Expired - Fee Related
-
2000
- 2000-04-07 GR GR20000400866T patent/GR3033173T3/el not_active IP Right Cessation
Also Published As
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| Publication | Publication Date | Title |
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