SI3475288T1 - Postopek za pripravo visokočistega prasugrela - Google Patents

Postopek za pripravo visokočistega prasugrela

Info

Publication number
SI3475288T1
SI3475288T1 SI201731047T SI201731047T SI3475288T1 SI 3475288 T1 SI3475288 T1 SI 3475288T1 SI 201731047 T SI201731047 T SI 201731047T SI 201731047 T SI201731047 T SI 201731047T SI 3475288 T1 SI3475288 T1 SI 3475288T1
Authority
SI
Slovenia
Prior art keywords
preparation
purity prasugrel
prasugrel
purity
Prior art date
Application number
SI201731047T
Other languages
English (en)
Inventor
Jozsef Neu
Tamas Szabo
Sandor Garadnay
Original Assignee
Richter Gedeon Nyrt.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Nyrt. filed Critical Richter Gedeon Nyrt.
Publication of SI3475288T1 publication Critical patent/SI3475288T1/sl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SI201731047T 2016-06-23 2017-06-22 Postopek za pripravo visokočistega prasugrela SI3475288T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
HU1600389A HU231079B1 (hu) 2016-06-23 2016-06-23 Eljárás nagytisztaságú Prasugrel előállítására bromopentil szennyezés eltávolításával
PCT/IB2017/053721 WO2017221187A1 (en) 2016-06-23 2017-06-22 Process for the preparation of high-purity prasugrel
EP17739322.0A EP3475288B1 (en) 2016-06-23 2017-06-22 Process for the preparation of high-purity prasugrel

Publications (1)

Publication Number Publication Date
SI3475288T1 true SI3475288T1 (sl) 2022-02-28

Family

ID=89992201

Family Applications (1)

Application Number Title Priority Date Filing Date
SI201731047T SI3475288T1 (sl) 2016-06-23 2017-06-22 Postopek za pripravo visokočistega prasugrela

Country Status (15)

Country Link
US (1) US20190211029A1 (sl)
EP (1) EP3475288B1 (sl)
CN (1) CN109311907B (sl)
CY (1) CY1124883T1 (sl)
DK (1) DK3475288T3 (sl)
EA (1) EA201892806A1 (sl)
ES (1) ES2901555T3 (sl)
HR (1) HRP20220126T1 (sl)
HU (2) HU231079B1 (sl)
LT (1) LT3475288T (sl)
PL (1) PL3475288T3 (sl)
PT (1) PT3475288T (sl)
RS (1) RS62771B1 (sl)
SI (1) SI3475288T1 (sl)
WO (1) WO2017221187A1 (sl)

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI101150B (fi) 1991-09-09 1998-04-30 Sankyo Co Menetelmä lääkeaineina käyttökelpoisten tetrahydrotienopyridiinin johd annaisten valmistamiseksi
ATE207072T1 (de) 1995-07-11 2001-11-15 Chemetall Gmbh Gelöstes methyllithium enthaltendes synthesemittel
DE60134508D1 (de) 2000-07-06 2008-07-31 Daiichi Sankyo Co Ltd Säure-Additionssalze von Hydropyridinderivaten
TWI318571B (en) 2005-06-10 2009-12-21 Lilly Co Eli Formulation of a thienopyridine platelet aggregation inhibitor
JP5844028B2 (ja) 2006-04-04 2016-01-13 ケージー アクキュイシチオン エルエルシー 抗血小板薬及び酸阻害薬を含む経口剤形
TWI392681B (zh) 2006-04-06 2013-04-11 Daiichi Sankyo Co Ltd 高純度普拉格雷及其酸加成鹽之製法
TWI417295B (zh) 2007-03-02 2013-12-01 Daiichi Sankyo Co Ltd 高純度之普拉斯克列鹽酸鹽之製法
WO2009062044A2 (en) * 2007-11-09 2009-05-14 Dr. Reddy's Laboratories Ltd. Processes for the preparation of prasugrel, and its salts and polymorphs
WO2009066326A2 (en) 2007-11-19 2009-05-28 Msn Laboratories Limited Improved process for the preparation of prasugrel and its pharmaceutically acceptable salts
HU230262B1 (hu) 2007-11-27 2015-11-30 Egis Gyógyszergyár Nyilvánosan Működő Részvénytársaság Eljárás gyógyszeripari intermedierek előállítására
WO2010015144A1 (zh) 2008-08-02 2010-02-11 鲁南制药集团股份有限公司 普拉格雷硫酸氢盐及其药物组合物和应用
WO2009122440A1 (en) 2008-03-31 2009-10-08 Torrent Pharmaceuticals Ltd. PROCESS FOR THE PREPARATION OF 2-ACETOXY-5-(α -CYCLOPRPYLCARBONYL -2-FLUOROBENZYL)-4,5,6,7-TETRAHYDROTHIENO[3,2-C]PYRIDINE
ATE482961T1 (de) 2008-04-25 2010-10-15 Sandoz Ag Hydrogensulfat von 2-acetoxy-5-(a- cyclopropylcarbonyl-2-fluorbenzyl)-4,5,6,7- tetrahydrothienoä3,2-cüpyridin und dessen zubereitung
CN101402642B (zh) * 2008-11-11 2013-01-09 上海现代制药股份有限公司 一种新型环保制备普拉格雷的方法
CZ2008748A3 (cs) 2008-11-26 2010-06-02 Zentiva, A. S Zpusob výroby vysoce cistého 5-[2-cyklopropyl-1-(2-fluorfenyl)-2-oxoethyl]-4,5,6,7-tetrahydrothieno[3,2-c] pyridin-2-yl acetátu, prasugrelu
EP2499147A4 (en) 2009-10-07 2013-03-06 Msn Lab Ltd IMPROVED METHODS FOR THE PRODUCTION OF PRASUGREL AND PHARMACEUTICAL ACCEPTABLE SALTS THEREOF
WO2012001486A1 (en) 2010-06-28 2012-01-05 Mayuka Labs Pvt. Ltd. An improved process for the preparation of prasugrel hydrochloride and its intermediates
US20130274284A1 (en) * 2010-08-06 2013-10-17 Dr. Reddy's Laboratories, Inc. Preparation of prasugrel hydrochloride
HUP1000565A2 (en) 2010-10-22 2012-05-02 Egis Gyogyszergyar Nyrt Process for the preparation of pharmaceutically active compound and intermediers
WO2012153348A2 (en) 2011-05-09 2012-11-15 Glenmark Generics Limited Process for preparation of prasugrel and its intermediates
WO2013014295A1 (en) 2011-07-28 2013-01-31 Laboratorios Lesvi, S. L. Process for preparing prasugrel
HU230649B1 (hu) 2013-01-24 2017-05-29 Egis Gyógyszergyár Nyilvánosan Működő Részvénytársaság Javított eljárás prasugrel gyógyszeripari hatóanyag és az 1-ciklopropil-2-(2-fluorofenil)-etanon intermedier előállítására
CN103524530A (zh) * 2013-10-24 2014-01-22 广州邦民制药厂有限公司 普拉格雷氢溴酸盐及其制备方法

Also Published As

Publication number Publication date
RS62771B1 (sr) 2022-01-31
CN109311907B (zh) 2022-09-13
WO2017221187A1 (en) 2017-12-28
ES2901555T3 (es) 2022-03-22
DK3475288T3 (da) 2022-01-03
US20190211029A1 (en) 2019-07-11
CN109311907A (zh) 2019-02-05
CY1124883T1 (el) 2022-11-25
HRP20220126T1 (hr) 2022-04-15
EP3475288B1 (en) 2021-11-03
EA201892806A1 (ru) 2019-07-31
HUE056560T2 (hu) 2022-02-28
PL3475288T3 (pl) 2022-02-21
EP3475288A1 (en) 2019-05-01
PT3475288T (pt) 2021-12-06
HU231079B1 (hu) 2020-06-29
LT3475288T (lt) 2021-12-27
HUP1600389A2 (en) 2017-12-28

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