SI3157531T1 - Metode in pripravki za stimulacijo črevesnega enteroendkrinega sistema za zdravljenje bolezni ali stanj, ki so povezani z le-tem - Google Patents

Metode in pripravki za stimulacijo črevesnega enteroendkrinega sistema za zdravljenje bolezni ali stanj, ki so povezani z le-tem

Info

Publication number
SI3157531T1
SI3157531T1 SI201531637T SI201531637T SI3157531T1 SI 3157531 T1 SI3157531 T1 SI 3157531T1 SI 201531637 T SI201531637 T SI 201531637T SI 201531637 T SI201531637 T SI 201531637T SI 3157531 T1 SI3157531 T1 SI 3157531T1
Authority
SI
Slovenia
Prior art keywords
stimulation
compositions
methods
same
treating diseases
Prior art date
Application number
SI201531637T
Other languages
English (en)
Slovenian (sl)
Inventor
Michael Zasloff
Original Assignee
Enterin, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Enterin, Inc. filed Critical Enterin, Inc.
Publication of SI3157531T1 publication Critical patent/SI3157531T1/sl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J41/00Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0005Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/10Laxatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Steroid Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)
SI201531637T 2014-06-23 2015-06-22 Metode in pripravki za stimulacijo črevesnega enteroendkrinega sistema za zdravljenje bolezni ali stanj, ki so povezani z le-tem SI3157531T1 (sl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201462015657P 2014-06-23 2014-06-23
US14/329,627 US10040817B2 (en) 2013-10-03 2014-07-11 Methods and compositions for stimulation of the intestinal enteroendocrine system for treating diseases or conditions related to the same
PCT/US2015/036935 WO2015200195A1 (en) 2014-06-23 2015-06-22 Methods and compositions for stimulation of the intestinal enteroendocrine system for treating diseases or conditions related to the same
EP15811714.3A EP3157531B1 (en) 2014-06-23 2015-06-22 Methods and compositions for stimulation of the intestinal enteroendocrine system for treating diseases or conditions related to the same

Publications (1)

Publication Number Publication Date
SI3157531T1 true SI3157531T1 (sl) 2021-09-30

Family

ID=54869043

Family Applications (1)

Application Number Title Priority Date Filing Date
SI201531637T SI3157531T1 (sl) 2014-06-23 2015-06-22 Metode in pripravki za stimulacijo črevesnega enteroendkrinega sistema za zdravljenje bolezni ali stanj, ki so povezani z le-tem

Country Status (19)

Country Link
US (10) US10040817B2 (enExample)
EP (1) EP3157531B1 (enExample)
JP (2) JP6692300B2 (enExample)
CN (2) CN113559108A (enExample)
BR (1) BR112016029917A2 (enExample)
CA (1) CA2951720C (enExample)
CY (1) CY1124554T1 (enExample)
DK (1) DK3157531T3 (enExample)
ES (1) ES2878077T3 (enExample)
HR (1) HRP20211005T1 (enExample)
HU (1) HUE054828T2 (enExample)
LT (1) LT3157531T (enExample)
MX (2) MX382442B (enExample)
PL (1) PL3157531T3 (enExample)
PT (1) PT3157531T (enExample)
RS (1) RS62064B1 (enExample)
SI (1) SI3157531T1 (enExample)
SM (1) SMT202100373T1 (enExample)
WO (1) WO2015200195A1 (enExample)

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US10040817B2 (en) * 2013-10-03 2018-08-07 Enterin Laboratories, Inc. Methods and compositions for stimulation of the intestinal enteroendocrine system for treating diseases or conditions related to the same
US20160058730A1 (en) * 2014-08-29 2016-03-03 Cadila Healthcare Limited Pharmaceutical compositions of teriflunomide
US20180344748A1 (en) * 2017-05-31 2018-12-06 Enterin Laboratories, Inc. Methods and compositions for preventing or treating chronic inflammatory diseases
US11083735B2 (en) * 2017-09-08 2021-08-10 Enterin, Inc. Methods for treating sleep disorders, sleep disturbances, and related symptoms using aminosterol compositions
MA50536A (fr) 2017-10-30 2020-09-09 Enterin Inc Nouvelles formes solides de squalamine et procédés pour les produire
CN112312917A (zh) * 2018-03-27 2021-02-02 因特尔公司 用于治疗幻觉及其相关病症的方法和组合物
US20190381071A1 (en) * 2018-06-13 2019-12-19 Enterin, Inc. Methods and compositions for treating and/or preventing the progression and/or onset of age-related neurodegeneration
US11464789B2 (en) 2018-08-03 2022-10-11 Enterin, Inc. Aminosterol compositions and methods of using the same for treating schizophrenia
EP3829587A4 (en) * 2018-08-03 2022-07-20 Enterin, Inc. COMPOSITIONS AND METHODS FOR TREATMENT OF BRAIN AND GUESS DISORDERS
US20210315907A1 (en) * 2018-08-03 2021-10-14 Enterin, Inc, Compositions and methods for treating brain-gut disorders
EP3829537A4 (en) * 2018-08-03 2022-09-21 Enterin, Inc. LOW DOSAGE INTRANASAL DOSAGE FORMS OF AMINOSTEROL AND METHODS OF USE THEREOF
US20230125585A1 (en) * 2019-08-02 2023-04-27 Enterin, Inc. Dosing protocols and regimens for aminosterol treatment

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US5352682A (en) 1993-03-08 1994-10-04 Digestive Care Inc. Compositions containing salts of bile acid-aminosalicylate conjugates
ATE169930T1 (de) 1993-03-10 1998-09-15 Magainin Pharma Steroidderivate, pharmazeutische zusammensetzungen die sie enthalten und ihre verwendung als antibiotika oder desinfektionsmittel
US5840740A (en) 1995-06-07 1998-11-24 Magainin Pharmaceuticals Inc. Aminosterol compounds and a method of treating infection using the aminosterol compounds
US5856535A (en) 1994-08-18 1999-01-05 Magainin Pharmaceuticals, Inc. Aminosterol ester compounds
WO1996008270A2 (en) 1994-09-13 1996-03-21 Magainin Pharmaceuticals Inc. Method for inhibiting sexually transmitted diseases using magaining antimicrobials or squalamine compounds
US5834453A (en) 1995-05-30 1998-11-10 Lehigh University Methods for the manufacture and use of antimicrobial sterol conjugates
PT832094E (pt) * 1995-06-07 2004-06-30 Genaera Corp Compostos de aminoesterol uteis como inibidores do permutador sodio/protao )nhe) metodos e composicoes farmaceuticas empregando estes inibidores e processos para avaliacao da eficacia inibidora de nhe dos compostos
US5847172A (en) 1995-06-07 1998-12-08 Magainin Pharmaceuticals Inc. Certain aminosterol compounds and pharmaceutical compositions including these compounds
US5840936A (en) 1995-06-07 1998-11-24 Magainin Pharmaceuticals Inc. Aminosterol compounds useful as inhibitors of the sodium/proton exchanger (NHE)
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US5763430A (en) 1995-06-07 1998-06-09 Magainin Pharmaceuticals Inc. Method of treating a viral infection by administering a steroid compound
US5792635A (en) * 1995-06-07 1998-08-11 Magainin Pharmaceuticals, Inc. Method of inhibiting the sodium/proton exchanger NHE3 and method of inhibiting growth by administering squalamine
US5874597A (en) 1995-06-07 1999-02-23 Magainin Pharmaceuticals, Inc. Certain aminosterol compounds and pharmaceutical compositions including these compounds
US5994336A (en) 1995-06-07 1999-11-30 Magainin Pharmaceuticals Inc. Method of inhibiting proliferation of cells by administering an aminosterol compound
US5795885A (en) 1995-06-07 1998-08-18 Magainin Pharmaceuticals Inc. Method of inhibiting profileration of cells by administering an aminosterol compound
US5744453A (en) 1996-01-05 1998-04-28 Mintz; Clifford S. Polyamine conjugates for treatment of infection
US6596712B2 (en) 1996-04-26 2003-07-22 Genaera Corporation Treatment of carcinomas using squalamine in combination with other anti-cancer agents or modalities
DK0910382T3 (da) 1996-04-26 2003-10-06 Genaera Corp Squalamin i kombination med andre anticancermidler til behandling af tumorer
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US8623416B2 (en) 2009-11-25 2014-01-07 Michael Zasloff Formulations comprising aminosterols
JP6165843B2 (ja) 2012-04-20 2017-07-19 オーエイチアール・ファーマシューティカル・インコーポレイテッドOhr Pharmaceutical,Inc. Ptp1b関連疾患の処置のためのアミノステロイド化合物
CN102813659A (zh) * 2012-08-21 2012-12-12 贵阳中医学院 20α-二甲胺基- 2α-羟基-3β-惕洛酰胺基-5α-孕甾烷的用途
EP2934543B1 (en) 2012-12-20 2018-10-31 Mount Desert Island Biological Laboratory Stimulation and enhancement of regeneration of tissues
US10040817B2 (en) 2013-10-03 2018-08-07 Enterin Laboratories, Inc. Methods and compositions for stimulation of the intestinal enteroendocrine system for treating diseases or conditions related to the same

Also Published As

Publication number Publication date
US10633413B2 (en) 2020-04-28
CY1124554T1 (el) 2022-07-22
DK3157531T3 (da) 2021-07-05
PL3157531T3 (pl) 2021-11-15
MX2016017368A (es) 2017-08-24
US20180319837A1 (en) 2018-11-08
US11440936B2 (en) 2022-09-13
SMT202100373T1 (it) 2021-07-12
US10208080B2 (en) 2019-02-19
EP3157531A1 (en) 2017-04-26
US10208079B2 (en) 2019-02-19
US10196420B2 (en) 2019-02-05
CA2951720A1 (en) 2015-12-30
MX2021005489A (es) 2021-06-18
US20150368290A1 (en) 2015-12-24
US10040817B2 (en) 2018-08-07
MX382442B (es) 2025-03-13
CN106535902A (zh) 2017-03-22
US10975116B2 (en) 2021-04-13
EP3157531B1 (en) 2021-03-31
BR112016029917A2 (pt) 2017-08-22
JP7010979B2 (ja) 2022-02-10
US20220220148A1 (en) 2022-07-14
JP2020097587A (ja) 2020-06-25
CA2951720C (en) 2023-09-26
WO2015200195A1 (en) 2015-12-30
HUE054828T2 (hu) 2021-10-28
HRP20211005T1 (hr) 2021-09-17
US20180002370A1 (en) 2018-01-04
CN113559108A (zh) 2021-10-29
US20190185513A1 (en) 2019-06-20
LT3157531T (lt) 2021-07-12
PT3157531T (pt) 2021-07-01
RS62064B1 (sr) 2021-07-30
US20190194243A1 (en) 2019-06-27
JP6692300B2 (ja) 2020-05-13
ES2878077T3 (es) 2021-11-18
EP3157531A4 (en) 2018-05-16
US20180327445A1 (en) 2018-11-15
JP2017519775A (ja) 2017-07-20
US20170327530A1 (en) 2017-11-16
CN106535902B (zh) 2021-05-25
US20170326156A1 (en) 2017-11-16
US20190194244A1 (en) 2019-06-27

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