HRP20211005T1 - Postupci i pripravci za stimuliranje crijevnog enteroendokrinog sustava u svrhu liječenja bolesti ili patoloških stanja u svezi toga - Google Patents

Postupci i pripravci za stimuliranje crijevnog enteroendokrinog sustava u svrhu liječenja bolesti ili patoloških stanja u svezi toga Download PDF

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Publication number
HRP20211005T1
HRP20211005T1 HRP20211005TT HRP20211005T HRP20211005T1 HR P20211005 T1 HRP20211005 T1 HR P20211005T1 HR P20211005T T HRP20211005T T HR P20211005TT HR P20211005 T HRP20211005 T HR P20211005T HR P20211005 T1 HRP20211005 T1 HR P20211005T1
Authority
HR
Croatia
Prior art keywords
preparation
use according
aminosterol
disease
medications
Prior art date
Application number
HRP20211005TT
Other languages
English (en)
Croatian (hr)
Inventor
Michael Zasloff
Original Assignee
Enterin, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Enterin, Inc. filed Critical Enterin, Inc.
Publication of HRP20211005T1 publication Critical patent/HRP20211005T1/hr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/10—Laxatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Steroid Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)
HRP20211005TT 2014-06-23 2015-06-22 Postupci i pripravci za stimuliranje crijevnog enteroendokrinog sustava u svrhu liječenja bolesti ili patoloških stanja u svezi toga HRP20211005T1 (hr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201462015657P 2014-06-23 2014-06-23
US14/329,627 US10040817B2 (en) 2013-10-03 2014-07-11 Methods and compositions for stimulation of the intestinal enteroendocrine system for treating diseases or conditions related to the same
EP15811714.3A EP3157531B1 (en) 2014-06-23 2015-06-22 Methods and compositions for stimulation of the intestinal enteroendocrine system for treating diseases or conditions related to the same
PCT/US2015/036935 WO2015200195A1 (en) 2014-06-23 2015-06-22 Methods and compositions for stimulation of the intestinal enteroendocrine system for treating diseases or conditions related to the same

Publications (1)

Publication Number Publication Date
HRP20211005T1 true HRP20211005T1 (hr) 2021-09-17

Family

ID=54869043

Family Applications (1)

Application Number Title Priority Date Filing Date
HRP20211005TT HRP20211005T1 (hr) 2014-06-23 2015-06-22 Postupci i pripravci za stimuliranje crijevnog enteroendokrinog sustava u svrhu liječenja bolesti ili patoloških stanja u svezi toga

Country Status (19)

Country Link
US (10) US10040817B2 (enExample)
EP (1) EP3157531B1 (enExample)
JP (2) JP6692300B2 (enExample)
CN (2) CN113559108A (enExample)
BR (1) BR112016029917A2 (enExample)
CA (1) CA2951720C (enExample)
CY (1) CY1124554T1 (enExample)
DK (1) DK3157531T3 (enExample)
ES (1) ES2878077T3 (enExample)
HR (1) HRP20211005T1 (enExample)
HU (1) HUE054828T2 (enExample)
LT (1) LT3157531T (enExample)
MX (2) MX382442B (enExample)
PL (1) PL3157531T3 (enExample)
PT (1) PT3157531T (enExample)
RS (1) RS62064B1 (enExample)
SI (1) SI3157531T1 (enExample)
SM (1) SMT202100373T1 (enExample)
WO (1) WO2015200195A1 (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10040817B2 (en) * 2013-10-03 2018-08-07 Enterin Laboratories, Inc. Methods and compositions for stimulation of the intestinal enteroendocrine system for treating diseases or conditions related to the same
US20160058730A1 (en) * 2014-08-29 2016-03-03 Cadila Healthcare Limited Pharmaceutical compositions of teriflunomide
WO2018222665A1 (en) * 2017-05-31 2018-12-06 Enterin Laboratories, Inc. Methods and compositions for preventing or treating inflammatory diseases
EP3678671A4 (en) * 2017-09-08 2022-12-07 Enterin, Inc. METHODS OF TREATMENT OF SLEEPING DISEASES, SLEEP DISORDERS AND RELATED SYMPTOMS USING AMINOSTEROL COMPOSITIONS
MA50536A (fr) * 2017-10-30 2020-09-09 Enterin Inc Nouvelles formes solides de squalamine et procédés pour les produire
KR20200146038A (ko) * 2018-03-27 2020-12-31 엔테린, 인코포레이티드 환각 및 이와 관련된 상태를 치료하는 방법 및 조성물
JP2021527090A (ja) * 2018-06-13 2021-10-11 エンターイン、 インコーポレイテッドEnterin, Inc. 老化関連神経変性の進行および/または発症を治療および/または予防するための方法および組成物
US11464789B2 (en) 2018-08-03 2022-10-11 Enterin, Inc. Aminosterol compositions and methods of using the same for treating schizophrenia
WO2020028810A1 (en) * 2018-08-03 2020-02-06 Enterin Laboratories Compositions and methods for treating brain-gut disorders
WO2020028791A1 (en) * 2018-08-03 2020-02-06 Enterin Laboratories Low dosage intranasal aminosterol dosage forms and methods of using the same
US20210315907A1 (en) * 2018-08-03 2021-10-14 Enterin, Inc, Compositions and methods for treating brain-gut disorders
US20230125585A1 (en) * 2019-08-02 2023-04-27 Enterin, Inc. Dosing protocols and regimens for aminosterol treatment
CN115551871A (zh) * 2020-03-19 2022-12-30 因特尔公司 角鲨胺的晶型

Family Cites Families (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5192756A (en) 1992-03-18 1993-03-09 The Children's Hospital Of Pennsylvania Aminosterol antibiotic
US5352682A (en) 1993-03-08 1994-10-04 Digestive Care Inc. Compositions containing salts of bile acid-aminosalicylate conjugates
CA2157594A1 (en) 1993-03-10 1994-09-15 Leah L. Frye Steroid derivatives, pharmaceutical compositions containing them, and their use as antibiotics or disinfectants
US5840740A (en) 1995-06-07 1998-11-24 Magainin Pharmaceuticals Inc. Aminosterol compounds and a method of treating infection using the aminosterol compounds
US5856535A (en) 1994-08-18 1999-01-05 Magainin Pharmaceuticals, Inc. Aminosterol ester compounds
AU3512595A (en) 1994-09-13 1996-03-29 Magainin Pharmaceuticals, Inc. Method for inhibiting sexually transmitted diseases using magaining antimicrobials or squalamine compounds
US5834453A (en) 1995-05-30 1998-11-10 Lehigh University Methods for the manufacture and use of antimicrobial sterol conjugates
US5795885A (en) 1995-06-07 1998-08-18 Magainin Pharmaceuticals Inc. Method of inhibiting profileration of cells by administering an aminosterol compound
AU723663C (en) * 1995-06-07 2001-11-01 Magainin Pharmaceuticals, Inc. Aminosterol compounds useful as inhibitors of the sodium/proton exchanger (NHE), pharmaceutical methods and compositions employing such inhibitors, and processes for evaluating the NHE-inhibitory efficacy of compounds
US5994336A (en) 1995-06-07 1999-11-30 Magainin Pharmaceuticals Inc. Method of inhibiting proliferation of cells by administering an aminosterol compound
US6143738A (en) 1995-06-07 2000-11-07 Magainin Pharmaceuticals, Inc. Therapeutic uses for an aminosterol compound
US5874597A (en) 1995-06-07 1999-02-23 Magainin Pharmaceuticals, Inc. Certain aminosterol compounds and pharmaceutical compositions including these compounds
US5847172A (en) 1995-06-07 1998-12-08 Magainin Pharmaceuticals Inc. Certain aminosterol compounds and pharmaceutical compositions including these compounds
US5763430A (en) 1995-06-07 1998-06-09 Magainin Pharmaceuticals Inc. Method of treating a viral infection by administering a steroid compound
US5840936A (en) 1995-06-07 1998-11-24 Magainin Pharmaceuticals Inc. Aminosterol compounds useful as inhibitors of the sodium/proton exchanger (NHE)
US5792635A (en) 1995-06-07 1998-08-11 Magainin Pharmaceuticals, Inc. Method of inhibiting the sodium/proton exchanger NHE3 and method of inhibiting growth by administering squalamine
US5744453A (en) 1996-01-05 1998-04-28 Mintz; Clifford S. Polyamine conjugates for treatment of infection
US6596712B2 (en) 1996-04-26 2003-07-22 Genaera Corporation Treatment of carcinomas using squalamine in combination with other anti-cancer agents or modalities
PT910382E (pt) 1996-04-26 2003-10-31 Genaera Corp Esqualamina em combinacao com outros agentes anti-cancro para o tratamento de tumores
US7410959B1 (en) * 2000-07-13 2008-08-12 Genaera Corporation Therapeutic uses for aminosterol compounds
JP2002515035A (ja) 1996-05-17 2002-05-21 ジェネーラ・コーポレーション アミノステロール化合物の治療学的使用
WO1998019682A1 (en) 1996-11-01 1998-05-14 Magainin Pharmaceuticals Inc. Certain aminosterol compounds and uses therefor
CA2339174C (en) 1998-08-12 2009-01-06 Magainin Pharmaceuticals, Inc. Aminosterol compounds and uses thereof
US6288089B1 (en) * 1998-12-21 2001-09-11 Michael Zawada Use of kinase inhibitors for treating neurodegenerative diseases
AU2002230398A1 (en) 2000-10-06 2002-04-29 Xenoport, Inc. Bile-acid conjugates for providing sustained systemic concentrations of drugs
WO2002044324A2 (en) * 2000-10-06 2002-06-06 Xenoport, Inc. Bile-acid derived compounds for enhancing oral absorption and systemic bioavailability of drugs
ES2716404T3 (es) * 2002-01-28 2019-06-12 Kyowa Hakko Kogyo Kk Antagonistas de receptores A2A para su uso en el tratamiento de trastornos del movimiento
WO2004034963A2 (en) 2002-05-17 2004-04-29 Eisai Co., Ltd. Methods and compositions using cholinesterase inhibitors
US7981876B2 (en) 2005-04-25 2011-07-19 Ohr Pharmaceuticals, Inc. Polymorphic and amorphous salt forms of squalamine dilactate
CA2985271A1 (en) 2007-09-06 2009-03-12 Ohr Pharmaceutical, Inc. A method for treating diabetes
US8247435B2 (en) * 2009-02-19 2012-08-21 Thornthwaite Jerry T Formulations for treating human and animal diseases
WO2011056650A2 (en) 2009-10-27 2011-05-12 Michael Zasloff Methods and compositions for treating and preventing viral infections
WO2011066260A2 (en) 2009-11-25 2011-06-03 Michael Zasloff Formulations comprising aminosterols
KR20150003798A (ko) 2012-04-20 2015-01-09 오에이치알 파마서티컬, 인코포레이티드 Ptp1b 연관 질병의 치료용 아미노스테로이드
CN102813659A (zh) * 2012-08-21 2012-12-12 贵阳中医学院 20α-二甲胺基- 2α-羟基-3β-惕洛酰胺基-5α-孕甾烷的用途
EP2934543B1 (en) 2012-12-20 2018-10-31 Mount Desert Island Biological Laboratory Stimulation and enhancement of regeneration of tissues
US10040817B2 (en) 2013-10-03 2018-08-07 Enterin Laboratories, Inc. Methods and compositions for stimulation of the intestinal enteroendocrine system for treating diseases or conditions related to the same

Also Published As

Publication number Publication date
ES2878077T3 (es) 2021-11-18
PL3157531T3 (pl) 2021-11-15
CN106535902A (zh) 2017-03-22
EP3157531A1 (en) 2017-04-26
US11440936B2 (en) 2022-09-13
US10208079B2 (en) 2019-02-19
BR112016029917A2 (pt) 2017-08-22
SI3157531T1 (sl) 2021-09-30
US10633413B2 (en) 2020-04-28
US10040817B2 (en) 2018-08-07
JP6692300B2 (ja) 2020-05-13
CN113559108A (zh) 2021-10-29
US20190194244A1 (en) 2019-06-27
US20180327445A1 (en) 2018-11-15
JP7010979B2 (ja) 2022-02-10
DK3157531T3 (da) 2021-07-05
PT3157531T (pt) 2021-07-01
US20180002370A1 (en) 2018-01-04
CN106535902B (zh) 2021-05-25
RS62064B1 (sr) 2021-07-30
US10975116B2 (en) 2021-04-13
CA2951720A1 (en) 2015-12-30
US20150368290A1 (en) 2015-12-24
CY1124554T1 (el) 2022-07-22
US20180319837A1 (en) 2018-11-08
US20170327530A1 (en) 2017-11-16
CA2951720C (en) 2023-09-26
SMT202100373T1 (it) 2021-07-12
US20190194243A1 (en) 2019-06-27
WO2015200195A1 (en) 2015-12-30
HUE054828T2 (hu) 2021-10-28
JP2020097587A (ja) 2020-06-25
US10208080B2 (en) 2019-02-19
JP2017519775A (ja) 2017-07-20
EP3157531B1 (en) 2021-03-31
US20190185513A1 (en) 2019-06-20
EP3157531A4 (en) 2018-05-16
MX2016017368A (es) 2017-08-24
MX2021005489A (es) 2021-06-18
MX382442B (es) 2025-03-13
US10196420B2 (en) 2019-02-05
LT3157531T (lt) 2021-07-12
US20170326156A1 (en) 2017-11-16
US20220220148A1 (en) 2022-07-14

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