JP6692300B2 - 腸の腸内分泌系を関連疾患又は病状の処置のために刺激する方法及び組成物 - Google Patents

腸の腸内分泌系を関連疾患又は病状の処置のために刺激する方法及び組成物 Download PDF

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JP6692300B2
JP6692300B2 JP2016574402A JP2016574402A JP6692300B2 JP 6692300 B2 JP6692300 B2 JP 6692300B2 JP 2016574402 A JP2016574402 A JP 2016574402A JP 2016574402 A JP2016574402 A JP 2016574402A JP 6692300 B2 JP6692300 B2 JP 6692300B2
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squalamine
aminosterol
composition
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JP2017519775A5 (enExample
JP2017519775A (ja
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ザスロフ，マイケル
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/10—Laxatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Steroid Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)
JP2016574402A 2014-06-23 2015-06-22 腸の腸内分泌系を関連疾患又は病状の処置のために刺激する方法及び組成物 Active JP6692300B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201462015657P 2014-06-23 2014-06-23
US62/015,657 2014-06-23
US14/329,627 US10040817B2 (en) 2013-10-03 2014-07-11 Methods and compositions for stimulation of the intestinal enteroendocrine system for treating diseases or conditions related to the same
US14/329,627 2014-07-11
PCT/US2015/036935 WO2015200195A1 (en) 2014-06-23 2015-06-22 Methods and compositions for stimulation of the intestinal enteroendocrine system for treating diseases or conditions related to the same

Related Child Applications (1)

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JP2020007206A Division JP7010979B2 (ja) 2014-06-23 2020-01-21 腸の腸内分泌系を関連疾患又は病状の処置のために刺激する方法及び組成物

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JP2017519775A JP2017519775A (ja) 2017-07-20
JP2017519775A5 JP2017519775A5 (enExample) 2018-06-07
JP6692300B2 true JP6692300B2 (ja) 2020-05-13

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JP2016574402A Active JP6692300B2 (ja) 2014-06-23 2015-06-22 腸の腸内分泌系を関連疾患又は病状の処置のために刺激する方法及び組成物
JP2020007206A Active JP7010979B2 (ja) 2014-06-23 2020-01-21 腸の腸内分泌系を関連疾患又は病状の処置のために刺激する方法及び組成物

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US (10) US10040817B2 (enExample)
EP (1) EP3157531B1 (enExample)
JP (2) JP6692300B2 (enExample)
CN (2) CN113559108A (enExample)
BR (1) BR112016029917A2 (enExample)
CA (1) CA2951720C (enExample)
CY (1) CY1124554T1 (enExample)
DK (1) DK3157531T3 (enExample)
ES (1) ES2878077T3 (enExample)
HR (1) HRP20211005T1 (enExample)
HU (1) HUE054828T2 (enExample)
LT (1) LT3157531T (enExample)
MX (2) MX382442B (enExample)
PL (1) PL3157531T3 (enExample)
PT (1) PT3157531T (enExample)
RS (1) RS62064B1 (enExample)
SI (1) SI3157531T1 (enExample)
SM (1) SMT202100373T1 (enExample)
WO (1) WO2015200195A1 (enExample)

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WO2018222665A1 (en) * 2017-05-31 2018-12-06 Enterin Laboratories, Inc. Methods and compositions for preventing or treating inflammatory diseases
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MA50536A (fr) * 2017-10-30 2020-09-09 Enterin Inc Nouvelles formes solides de squalamine et procédés pour les produire
KR20200146038A (ko) * 2018-03-27 2020-12-31 엔테린, 인코포레이티드 환각 및 이와 관련된 상태를 치료하는 방법 및 조성물
JP2021527090A (ja) * 2018-06-13 2021-10-11 エンターイン、 インコーポレイテッドＥｎｔｅｒｉｎ， Ｉｎｃ． 老化関連神経変性の進行および／または発症を治療および／または予防するための方法および組成物
US11464789B2 (en) 2018-08-03 2022-10-11 Enterin, Inc. Aminosterol compositions and methods of using the same for treating schizophrenia
WO2020028810A1 (en) * 2018-08-03 2020-02-06 Enterin Laboratories Compositions and methods for treating brain-gut disorders
WO2020028791A1 (en) * 2018-08-03 2020-02-06 Enterin Laboratories Low dosage intranasal aminosterol dosage forms and methods of using the same
US20210315907A1 (en) * 2018-08-03 2021-10-14 Enterin, Inc, Compositions and methods for treating brain-gut disorders
US20230125585A1 (en) * 2019-08-02 2023-04-27 Enterin, Inc. Dosing protocols and regimens for aminosterol treatment
CN115551871A (zh) * 2020-03-19 2022-12-30 因特尔公司 角鲨胺的晶型

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ES2878077T3 (es) 2021-11-18
PL3157531T3 (pl) 2021-11-15
CN106535902A (zh) 2017-03-22
EP3157531A1 (en) 2017-04-26
US11440936B2 (en) 2022-09-13
US10208079B2 (en) 2019-02-19
BR112016029917A2 (pt) 2017-08-22
SI3157531T1 (sl) 2021-09-30
US10633413B2 (en) 2020-04-28
US10040817B2 (en) 2018-08-07
CN113559108A (zh) 2021-10-29
US20190194244A1 (en) 2019-06-27
US20180327445A1 (en) 2018-11-15
JP7010979B2 (ja) 2022-02-10
DK3157531T3 (da) 2021-07-05
PT3157531T (pt) 2021-07-01
US20180002370A1 (en) 2018-01-04
CN106535902B (zh) 2021-05-25
RS62064B1 (sr) 2021-07-30
US10975116B2 (en) 2021-04-13
HRP20211005T1 (hr) 2021-09-17
CA2951720A1 (en) 2015-12-30
US20150368290A1 (en) 2015-12-24
CY1124554T1 (el) 2022-07-22
US20180319837A1 (en) 2018-11-08
US20170327530A1 (en) 2017-11-16
CA2951720C (en) 2023-09-26
SMT202100373T1 (it) 2021-07-12
US20190194243A1 (en) 2019-06-27
WO2015200195A1 (en) 2015-12-30
HUE054828T2 (hu) 2021-10-28
JP2020097587A (ja) 2020-06-25
US10208080B2 (en) 2019-02-19
JP2017519775A (ja) 2017-07-20
EP3157531B1 (en) 2021-03-31
US20190185513A1 (en) 2019-06-20
EP3157531A4 (en) 2018-05-16
MX2016017368A (es) 2017-08-24
MX2021005489A (es) 2021-06-18
MX382442B (es) 2025-03-13
US10196420B2 (en) 2019-02-05
LT3157531T (lt) 2021-07-12
US20170326156A1 (en) 2017-11-16
US20220220148A1 (en) 2022-07-14

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