SI3092224T1 - Selektivni NR2B antagonisti - Google Patents
Selektivni NR2B antagonistiInfo
- Publication number
- SI3092224T1 SI3092224T1 SI201530408T SI201530408T SI3092224T1 SI 3092224 T1 SI3092224 T1 SI 3092224T1 SI 201530408 T SI201530408 T SI 201530408T SI 201530408 T SI201530408 T SI 201530408T SI 3092224 T1 SI3092224 T1 SI 3092224T1
- Authority
- SI
- Slovenia
- Prior art keywords
- nr2b antagonists
- selective nr2b
- selective
- antagonists
- nr2b
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurosurgery (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201461925363P | 2014-01-09 | 2014-01-09 | |
EP15703328.3A EP3092224B1 (en) | 2014-01-09 | 2015-01-06 | Selective nr2b antagonists |
PCT/US2015/010262 WO2015105772A1 (en) | 2014-01-09 | 2015-01-06 | Selective nr2b antagonists |
Publications (1)
Publication Number | Publication Date |
---|---|
SI3092224T1 true SI3092224T1 (sl) | 2018-11-30 |
Family
ID=52463126
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SI201530408T SI3092224T1 (sl) | 2014-01-09 | 2015-01-06 | Selektivni NR2B antagonisti |
Country Status (27)
Country | Link |
---|---|
US (10) | US9221796B2 (sl) |
EP (1) | EP3092224B1 (sl) |
JP (1) | JP6543259B2 (sl) |
KR (1) | KR102311518B1 (sl) |
CN (1) | CN106061961B (sl) |
AR (1) | AR099071A1 (sl) |
AU (1) | AU2015205001A1 (sl) |
CA (1) | CA2936293A1 (sl) |
CL (1) | CL2016001763A1 (sl) |
DK (1) | DK3092224T3 (sl) |
EA (1) | EA201691413A1 (sl) |
ES (1) | ES2693250T3 (sl) |
HR (1) | HRP20181585T1 (sl) |
HU (1) | HUE041986T2 (sl) |
IL (1) | IL246599A0 (sl) |
LT (1) | LT3092224T (sl) |
MX (1) | MX2016008898A (sl) |
PE (1) | PE20160933A1 (sl) |
PL (1) | PL3092224T3 (sl) |
PT (1) | PT3092224T (sl) |
RS (1) | RS57830B1 (sl) |
SG (1) | SG11201605618WA (sl) |
SI (1) | SI3092224T1 (sl) |
TR (1) | TR201815579T4 (sl) |
TW (1) | TWI640515B (sl) |
UY (1) | UY35947A (sl) |
WO (1) | WO2015105772A1 (sl) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9221796B2 (en) * | 2014-01-09 | 2015-12-29 | Bristol-Myers Squibb Company | Selective NR2B antagonists |
KR20180063306A (ko) | 2015-10-14 | 2018-06-11 | 브리스톨-마이어스 스큅 컴퍼니 | 선택적 nr2b 길항제 |
US10501451B2 (en) | 2015-10-14 | 2019-12-10 | Bristol-Myers Squibb Company | Selective NR2B antagonists |
CN108203404A (zh) * | 2018-03-02 | 2018-06-26 | 上海博邦医药科技有限公司 | (r)-3-苯基哌啶或/和(s)-3-苯基哌啶以及尼拉帕尼的手性中间体的合成方法 |
US10781172B2 (en) | 2018-06-21 | 2020-09-22 | Northwestern University | Catalysts and methods for enantioselective conjugate additions of amines to unsaturated electrophiles |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2744448B1 (fr) | 1996-02-02 | 1998-04-24 | Pf Medicament | Nouvelles piperidines derivees d'aryl piperazine, ainsi que leur procede de preparation, les compositions pharmaceutiques et leur utilisation comme medicaments |
AU3818900A (en) | 1999-04-14 | 2000-11-02 | F. Hoffmann-La Roche Ag | Process for the preparation of substituted piperidines |
US6476041B1 (en) | 1999-10-29 | 2002-11-05 | Merck & Co., Inc. | 1,4 substituted piperidinyl NMDA/NR2B antagonists |
BR0110247A (pt) * | 2000-04-26 | 2003-03-05 | Warner Lambert Co | Derivado de ciclohexilamina como antagonistas de receptor de nmda seletivos em subtipo |
WO2003035641A1 (fr) | 2001-10-22 | 2003-05-01 | Shionogi & Co., Ltd. | Nouveau derive carbamoyl-pyrrolidone |
DK1648882T3 (da) | 2003-06-04 | 2008-11-24 | Merck & Co Inc | 3-fluor-piperidiner som NMDA/NR2B-antagonister |
EP1673367A1 (en) | 2003-10-08 | 2006-06-28 | Pfizer, Inc. | Fused lactam compounds |
EP2520567A3 (en) | 2006-02-23 | 2012-12-12 | Shionogi & Co., Ltd. | Nitrogen-containing heterocycle derivatives substituted with cyclic group |
KR20100045983A (ko) * | 2007-06-29 | 2010-05-04 | 에모리 유니버시티 | 신경보호를 위한 nmda 수용체 길항물질 |
US9221796B2 (en) * | 2014-01-09 | 2015-12-29 | Bristol-Myers Squibb Company | Selective NR2B antagonists |
-
2015
- 2015-01-05 US US14/589,205 patent/US9221796B2/en active Active
- 2015-01-06 EP EP15703328.3A patent/EP3092224B1/en active Active
- 2015-01-06 CN CN201580012735.9A patent/CN106061961B/zh active Active
- 2015-01-06 DK DK15703328.3T patent/DK3092224T3/en active
- 2015-01-06 PL PL15703328T patent/PL3092224T3/pl unknown
- 2015-01-06 ES ES15703328.3T patent/ES2693250T3/es active Active
- 2015-01-06 WO PCT/US2015/010262 patent/WO2015105772A1/en active Application Filing
- 2015-01-06 EA EA201691413A patent/EA201691413A1/ru unknown
- 2015-01-06 KR KR1020167021356A patent/KR102311518B1/ko active IP Right Grant
- 2015-01-06 CA CA2936293A patent/CA2936293A1/en not_active Abandoned
- 2015-01-06 SG SG11201605618WA patent/SG11201605618WA/en unknown
- 2015-01-06 MX MX2016008898A patent/MX2016008898A/es unknown
- 2015-01-06 SI SI201530408T patent/SI3092224T1/sl unknown
- 2015-01-06 PE PE2016001107A patent/PE20160933A1/es not_active Application Discontinuation
- 2015-01-06 AU AU2015205001A patent/AU2015205001A1/en not_active Abandoned
- 2015-01-06 TR TR2018/15579T patent/TR201815579T4/tr unknown
- 2015-01-06 JP JP2016545819A patent/JP6543259B2/ja not_active Expired - Fee Related
- 2015-01-06 HU HUE15703328A patent/HUE041986T2/hu unknown
- 2015-01-06 LT LTEP15703328.3T patent/LT3092224T/lt unknown
- 2015-01-06 PT PT15703328T patent/PT3092224T/pt unknown
- 2015-01-06 RS RS20181296A patent/RS57830B1/sr unknown
- 2015-01-08 TW TW104100592A patent/TWI640515B/zh not_active IP Right Cessation
- 2015-01-09 UY UY0001035947A patent/UY35947A/es unknown
- 2015-01-09 AR ARP150100065A patent/AR099071A1/es unknown
- 2015-10-13 US US14/882,041 patent/US20160081995A1/en not_active Abandoned
-
2016
- 2016-07-04 IL IL246599A patent/IL246599A0/en unknown
- 2016-07-08 CL CL2016001763A patent/CL2016001763A1/es unknown
-
2017
- 2017-05-25 US US15/604,904 patent/US20170258777A1/en not_active Abandoned
- 2017-09-15 US US15/706,172 patent/US20180000807A1/en not_active Abandoned
- 2017-12-19 US US15/846,672 patent/US20180110766A1/en not_active Abandoned
-
2018
- 2018-05-04 US US15/971,067 patent/US20180250283A1/en not_active Abandoned
- 2018-10-03 HR HRP20181585TT patent/HRP20181585T1/hr unknown
- 2018-12-19 US US16/225,850 patent/US20190117638A1/en not_active Abandoned
-
2019
- 2019-06-27 US US16/454,831 patent/US20190314358A1/en not_active Abandoned
-
2020
- 2020-01-30 US US16/777,114 patent/US20200163949A1/en not_active Abandoned
- 2020-09-04 US US17/012,781 patent/US20210121453A1/en not_active Abandoned
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
GB201411344D0 (en) | Cloning | |
GB201412161D0 (en) | Structure | |
GB2528078B (en) | Structure | |
IL258611A (en) | Selective nr2b antagonists | |
GB201412159D0 (en) | Morphable structure | |
GB2522522B (en) | Structure | |
HRP20181585T1 (hr) | Selektivni nr2b antagonisti | |
DK3177838T3 (en) | Fluid-redirecting structure | |
GB201420865D0 (en) | Boring device | |
HRP20182016T1 (hr) | Derivati etinila | |
GB201405651D0 (en) | Delivering an action | |
PL3163300T3 (pl) | Struktura oporowa | |
PL2898913T3 (pl) | Strzykawka | |
IL258603A (en) | Selective nr2b antagonists | |
GB201419494D0 (en) | Variations | |
GB2522039B (en) | I-beam | |
TWM489693U (en) | Nozzle structure | |
ZA201807767B (en) | Angiotensin-1-receptor antagonists | |
PT3464324T (pt) | Antagonistas de recetores da angiotensina-1 | |
GB201419398D0 (en) | Concept 82a | |
GB201414186D0 (en) | Secure tip | |
HU4455U (en) | Construction component set | |
AU358011S (en) | Short stool | |
GB201400123D0 (en) | Concept 82a |