SI2893045T1 - A method for selection of agents influencing intestinal motility disorders and pain - Google Patents

A method for selection of agents influencing intestinal motility disorders and pain Download PDF

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Publication number
SI2893045T1
SI2893045T1 SI201331106T SI201331106T SI2893045T1 SI 2893045 T1 SI2893045 T1 SI 2893045T1 SI 201331106 T SI201331106 T SI 201331106T SI 201331106 T SI201331106 T SI 201331106T SI 2893045 T1 SI2893045 T1 SI 2893045T1
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Slovenia
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agent
gastrointestinal
ability
reduce
mmc
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SI201331106T
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English (en)
Slovenian (sl)
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Eamonn Connolly
Wolfgang Kunze
John Bienenstock
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Biogaia Ab
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Application filed by Biogaia Ab filed Critical Biogaia Ab
Publication of SI2893045T1 publication Critical patent/SI2893045T1/en

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/135—Bacteria or derivatives thereof, e.g. probiotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/747—Lactobacilli, e.g. L. acidophilus or L. brevis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/0004—Screening or testing of compounds for diagnosis of disorders, assessment of conditions, e.g. renal clearance, gastric emptying, testing for diabetes, allergy, rheuma, pancreas functions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/06—Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/10—Laxatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00—Image analysis
    • G06T7/0002—Inspection of images, e.g. flaw detection
    • G06T7/0012—Biomedical image inspection
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00—Image analysis
    • G06T7/10—Segmentation; Edge detection
    • G06T7/13—Edge detection
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K2035/11—Medicinal preparations comprising living procariotic cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/225—Lactobacillus
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00—Indexing scheme for image analysis or image enhancement
    • G06T2207/30—Subject of image; Context of image processing
    • G06T2207/30004—Biomedical image processing
    • G06T2207/30092—Stomach; Gastric

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Mycology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Theoretical Computer Science (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Rheumatology (AREA)
  • Pathology (AREA)
  • Medical Informatics (AREA)
  • Urology & Nephrology (AREA)
  • Nutrition Science (AREA)
  • Radiology & Medical Imaging (AREA)
  • Quality & Reliability (AREA)
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SI201331106T 2012-09-03 2013-09-03 A method for selection of agents influencing intestinal motility disorders and pain SI2893045T1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261696277P 2012-09-03 2012-09-03
EP13756897.8A EP2893045B1 (en) 2012-09-03 2013-09-03 A method for selection of agents influencing intestinal motility disorders and pain
PCT/EP2013/068202 WO2014033330A1 (en) 2012-09-03 2013-09-03 A method for selection of agents influencing intestinal motility disorders and pain

Publications (1)

Publication Number Publication Date
SI2893045T1 true SI2893045T1 (en) 2018-08-31

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SI201331106T SI2893045T1 (en) 2012-09-03 2013-09-03 A method for selection of agents influencing intestinal motility disorders and pain

Country Status (27)

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US (5) US9555065B2 (OSRAM)
EP (2) EP3369808A1 (OSRAM)
JP (3) JP6259458B2 (OSRAM)
KR (1) KR102293438B1 (OSRAM)
CN (4) CN104918640B (OSRAM)
AU (1) AU2013308299B2 (OSRAM)
CA (2) CA3268968A1 (OSRAM)
CL (2) CL2015000490A1 (OSRAM)
CO (1) CO7350654A2 (OSRAM)
DK (1) DK2893045T3 (OSRAM)
ES (1) ES2681974T3 (OSRAM)
GE (1) GEP201706775B (OSRAM)
HK (1) HK1258778A1 (OSRAM)
HR (1) HRP20181033T1 (OSRAM)
IL (2) IL237397B (OSRAM)
IN (1) IN2015DN01572A (OSRAM)
LT (1) LT2893045T (OSRAM)
MX (2) MX362495B (OSRAM)
MY (2) MY182358A (OSRAM)
NZ (1) NZ705358A (OSRAM)
PH (1) PH12015500452B1 (OSRAM)
RU (1) RU2701348C2 (OSRAM)
SG (3) SG11201501297TA (OSRAM)
SI (1) SI2893045T1 (OSRAM)
UA (2) UA118339C2 (OSRAM)
WO (1) WO2014033330A1 (OSRAM)
ZA (1) ZA201501472B (OSRAM)

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CA2807242C (en) 2010-08-04 2017-05-02 Thomas Julius Borody Compositions for fecal floral transplantation and methods for making and using them and devices for delivering them
CN108094541A (zh) * 2018-01-11 2018-06-01 黑龙江完达山林海液奶有限公司 一种具有保健益生功能的风味发酵乳及其制备方法
HUE059963T2 (hu) * 2018-07-24 2023-01-28 Biogaia Ab Melatonintámogató baktériumok szelektálása és felhasználása az infantilis kólika csökkentésére
CN113966284B (zh) * 2019-06-05 2024-09-10 Avl移动技术公司 车辆轴组件
JP7337961B2 (ja) 2019-06-05 2023-09-04 エーヴィーエル パワートレイン エンジニアリング インコーポレイテッド 車両フレーム組立体と電源トレイ
JP7471324B2 (ja) 2019-06-05 2024-04-19 エーヴィーエル パワートレイン エンジニアリング インコーポレイテッド 車両フレームおよび電源アセンブリ、ならびに関連するシステムおよび方法
CN110186922B (zh) * 2019-06-25 2021-07-23 西安交通大学医学院第一附属医院 一种监测结肠移行性复合运动的实验装置及方法
US11843097B2 (en) 2019-09-10 2023-12-12 Avl Powertrain Engineering, Inc. Power supply control systems and methods
CN112710823B (zh) * 2020-12-17 2024-03-29 中国科学院深圳先进技术研究院 一种肠移行性复合运动的离体检测系统及其应用
CN114342878B (zh) * 2022-01-10 2022-09-30 南京鼓楼医院 一种慢传输型便秘动物模型的建立方法
CN117384804A (zh) * 2023-12-12 2024-01-12 北京三元食品股份有限公司 格氏乳杆菌b1-26及其应用

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PL200132B1 (pl) * 1998-08-21 2008-12-31 Novartis Ag Zastosowanie 3-(5-metoksy-1H-indol-3-ilometyleno)-N-pentylokarbazyimidoamidu
HUP0202388A3 (en) * 1999-07-06 2004-03-01 Enpharma L P Hamilton Method and composition for regulating gut motility and food intake and the novel activ ingredients
EP1565547B2 (en) * 2002-06-28 2012-09-19 Biosearch S.A. Probiotic strains, a process for the selection of them, compositions thereof, and their use
EP1384483A1 (en) * 2002-07-23 2004-01-28 Nestec S.A. Probiotics for treatment of irritable bowel disease (IBS) through improvement of gut neuromuscular function
TWI241912B (en) * 2002-10-30 2005-10-21 Food Industry Res & Dev Inst Novel Acid-and bile salt-resistant Lactobacillus isolates having the ability to lower and assimilate cholesterol
CN1663573B (zh) * 2004-03-04 2010-04-28 青岛东海药业有限公司 一种稳定安全的微生态制剂及其制备方法和用途
US20090233888A1 (en) * 2005-03-23 2009-09-17 Usc Stevens, University Of Southern California Treatment of disease conditions through modulation of hydrogen sulfide produced by small intestinal bacterial overgrowth
JP5036020B2 (ja) * 2005-11-30 2012-09-26 雪印メグミルク株式会社 腎周囲脂肪蓄積抑制剤
US7374924B2 (en) * 2006-06-05 2008-05-20 Biogaia Ab Use of selected lactic acid bacteria for reducing infantile colic
JP5019563B2 (ja) * 2006-06-16 2012-09-05 旭化成ケミカルズ株式会社 腸内細菌賦活剤
EP2200443B2 (en) * 2007-09-17 2021-06-30 Cornell University Branched chain fatty acids for prevention or treatment of gastrointestinal disorders
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WO2011148219A1 (en) * 2010-05-28 2011-12-01 Compagnie Gervais Danone Probiotic strains for use in improving the enteric nervous system
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CN102304489B (zh) * 2011-09-23 2013-06-12 北京龙科方舟生物工程技术有限公司 一株罗伊氏乳杆菌及其应用

Also Published As

Publication number Publication date
US10174388B2 (en) 2019-01-08
CN108904545A (zh) 2018-11-30
PH12015500452B1 (en) 2023-01-20
CL2017002826A1 (es) 2018-04-06
CO7350654A2 (es) 2015-08-10
MX362495B (es) 2019-01-21
US20190112676A1 (en) 2019-04-18
WO2014033330A1 (en) 2014-03-06
IL237397B (en) 2018-10-31
JP6476328B2 (ja) 2019-02-27
RU2701348C2 (ru) 2019-09-26
SG10202101556WA (en) 2021-03-30
JP2015529329A (ja) 2015-10-05
IL237397A0 (en) 2015-04-30
CN108753645A (zh) 2018-11-06
CN104918640B (zh) 2019-03-19
UA126374C2 (uk) 2022-09-28
MY182358A (en) 2021-01-20
JP2018090616A (ja) 2018-06-14
GEP201706775B (en) 2017-11-27
UA118339C2 (uk) 2019-01-10
HK1258778A1 (zh) 2019-11-22
US9555065B2 (en) 2017-01-31
MX2018013097A (es) 2020-09-02
CN108753645B (zh) 2019-10-22
JP6259458B2 (ja) 2018-01-10
IN2015DN01572A (OSRAM) 2015-07-03
CL2015000490A1 (es) 2015-05-29
MX2015002792A (es) 2015-05-07
JP2018029588A (ja) 2018-03-01
IL259652B (en) 2020-03-31
HK1211848A1 (en) 2016-06-03
NZ705358A (en) 2018-09-28
US20220306984A1 (en) 2022-09-29
US20170114422A1 (en) 2017-04-27
MY195532A (en) 2023-01-31
US20180023150A1 (en) 2018-01-25
SG11201501297TA (en) 2015-03-30
ZA201501472B (en) 2016-06-29
ES2681974T3 (es) 2018-09-17
EP2893045B1 (en) 2018-05-16
KR20150048201A (ko) 2015-05-06
LT2893045T (lt) 2018-07-25
US9816150B2 (en) 2017-11-14
PH12015500452A1 (en) 2015-04-20
CN109966511A (zh) 2019-07-05
CN104918640A (zh) 2015-09-16
HRP20181033T1 (hr) 2018-08-24
EP3369808A1 (en) 2018-09-05
HK1258774A1 (zh) 2019-11-22
RU2015112102A (ru) 2016-10-20
CA2883440A1 (en) 2014-03-06
AU2013308299A1 (en) 2015-03-26
DK2893045T3 (en) 2018-07-30
JP6322326B2 (ja) 2018-05-09
AU2013308299B2 (en) 2019-04-18
CA3268968A1 (en) 2025-11-29
EP2893045A1 (en) 2015-07-15
IL259652A (en) 2018-07-31
KR102293438B1 (ko) 2021-08-25
SG10201608055XA (en) 2016-11-29
US20150231186A1 (en) 2015-08-20

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