SI2861214T1 - Po meri narejeni liposomi za zdravljenje bakterijskih infekcij - Google Patents

Po meri narejeni liposomi za zdravljenje bakterijskih infekcij

Info

Publication number
SI2861214T1
SI2861214T1 SI201331806T SI201331806T SI2861214T1 SI 2861214 T1 SI2861214 T1 SI 2861214T1 SI 201331806 T SI201331806 T SI 201331806T SI 201331806 T SI201331806 T SI 201331806T SI 2861214 T1 SI2861214 T1 SI 2861214T1
Authority
SI
Slovenia
Prior art keywords
treatment
bacterial infections
custom made
made liposomes
liposomes
Prior art date
Application number
SI201331806T
Other languages
English (en)
Slovenian (sl)
Inventor
Eduard Babiychuk
Annette Draeger
Original Assignee
Universitaet Bern
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Universitaet Bern filed Critical Universitaet Bern
Publication of SI2861214T1 publication Critical patent/SI2861214T1/sl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A61K31/569Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone substituted in position 17 alpha, e.g. ethisterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/683Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
    • A61K31/688Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols both hydroxy compounds having nitrogen atoms, e.g. sphingomyelins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • A61P39/02Antidotes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Toxicology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Inorganic Chemistry (AREA)
  • Neurology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dermatology (AREA)
  • Pulmonology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
SI201331806T 2012-06-14 2013-06-13 Po meri narejeni liposomi za zdravljenje bakterijskih infekcij SI2861214T1 (sl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP12171924 2012-06-14
EP13153039 2013-01-29
EP13732388.7A EP2861214B1 (en) 2012-06-14 2013-06-13 Tailored liposomes for the treatment of bacterial infections
PCT/EP2013/062207 WO2013186286A1 (en) 2012-06-14 2013-06-13 Tailored liposomes for the treatment of bacterial infections

Publications (1)

Publication Number Publication Date
SI2861214T1 true SI2861214T1 (sl) 2021-01-29

Family

ID=48703423

Family Applications (1)

Application Number Title Priority Date Filing Date
SI201331806T SI2861214T1 (sl) 2012-06-14 2013-06-13 Po meri narejeni liposomi za zdravljenje bakterijskih infekcij

Country Status (19)

Country Link
US (4) US10744089B2 (enExample)
EP (2) EP2861214B1 (enExample)
JP (2) JP6382801B2 (enExample)
CN (2) CN104602672B (enExample)
AU (2) AU2013276565B2 (enExample)
BR (1) BR112014031278B1 (enExample)
CA (1) CA2875470C (enExample)
CY (1) CY1123337T1 (enExample)
DK (1) DK2861214T3 (enExample)
ES (1) ES2821502T3 (enExample)
HR (1) HRP20201761T1 (enExample)
HU (1) HUE051761T2 (enExample)
LT (1) LT2861214T (enExample)
PL (1) PL2861214T3 (enExample)
RS (1) RS60951B1 (enExample)
RU (1) RU2672106C2 (enExample)
SI (1) SI2861214T1 (enExample)
SM (1) SMT202000584T1 (enExample)
WO (1) WO2013186286A1 (enExample)

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US20170000875A1 (en) 2013-12-02 2017-01-05 Arytha Biosciences, Llc Toxoid preparation and uses thereof
US10739353B2 (en) * 2014-12-31 2020-08-11 Signpath Pharma, Inc. Suppression of cytokine release and cytokine storm
EP3397245A4 (en) * 2015-12-28 2019-08-28 MB Biotech Ltd. LIPOSOME FOR THE TREATMENT OF AUTOIMMUNE DISEASES
WO2017177073A1 (en) * 2016-04-07 2017-10-12 The United States Of America, As Represented By The Secretary, Department Of Health & Human Services Francisella lipids as broad anti-inflammatory therapeutics and associated methods of use
PL3471732T3 (pl) 2016-06-16 2020-10-19 Combioxin Sa Liposomy do leczenia infekcji wirusowych
CN110636839B (zh) * 2017-03-02 2023-06-27 康柏辛股份有限公司 抑制生物膜形成的脂质体
US11344497B1 (en) 2017-12-08 2022-05-31 Quicksilver Scientific, Inc. Mitochondrial performance enhancement nanoemulsion
AU2019254515B9 (en) * 2018-04-17 2025-06-26 Combioxin Sa Treatment of pneumonia
CN111971068B (zh) * 2018-04-20 2025-09-02 康柏辛股份有限公司 败血症和败血性休克的治疗
CN111214439B (zh) * 2018-11-23 2023-02-10 复旦大学 一种具有细菌成孔毒素吸附性能的纳米药物系统及其用途
CN115768499A (zh) 2020-01-20 2023-03-07 阿瑞萨生物科技有限责任公司 含有细胞膜的装置及其用途
WO2022026170A1 (en) * 2020-07-31 2022-02-03 Signpath Pharma, Inc. Suppression of cytokine release and cytokine storm
CN115054577B (zh) * 2022-05-17 2024-06-21 温州医科大学附属第二医院(温州医科大学附属育英儿童医院) 纳米解毒剂及其在中和mrsa穿孔毒素的应用

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US5741516A (en) * 1994-06-20 1998-04-21 Inex Pharmaceuticals Corporation Sphingosomes for enhanced drug delivery
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US20060198882A1 (en) * 2003-03-21 2006-09-07 Yechezkel Barenholz Stable liposomes or micelles comprising a sphinolipid and a peg-lipopolymer
LT3173073T (lt) 2004-05-03 2025-01-10 Ipsen Biopharm Ltd. Liposomos, skirtos vaistų pristatymui
US20090285878A1 (en) * 2004-11-05 2009-11-19 Tekmira Pharmaceuticals Corporation Compositions and methods for stabilizing liposomal drug formulations
JPWO2007018275A1 (ja) 2005-08-11 2009-02-19 独立行政法人産業技術総合研究所 ローリングモデルに基づく、送達媒体の設計
CN1939340A (zh) * 2005-09-29 2007-04-04 中国人民解放军军事医学科学院毒物药物研究所 脂质体制剂
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LT2861214T (lt) 2012-06-14 2020-12-28 Universität Bern Specialiai pritaikytos liposomos, skirtos bakterinių infekcijų gydymui
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Also Published As

Publication number Publication date
CY1123337T1 (el) 2021-12-31
CA2875470C (en) 2021-01-12
EP2861214B1 (en) 2020-08-05
AU2019201776B2 (en) 2020-11-12
RS60951B1 (sr) 2020-11-30
BR112014031278A2 (pt) 2017-06-27
US12599558B2 (en) 2026-04-14
CN104602672B (zh) 2018-12-25
US10744089B2 (en) 2020-08-18
JP2015519383A (ja) 2015-07-09
CN109549925A (zh) 2019-04-02
CN109549925B (zh) 2022-06-17
WO2013186286A1 (en) 2013-12-19
RU2672106C2 (ru) 2018-11-12
PL2861214T3 (pl) 2021-02-08
DK2861214T3 (da) 2020-10-12
HRP20201761T1 (hr) 2020-12-25
CA2875470A1 (en) 2013-12-19
BR112014031278B1 (pt) 2020-12-01
US20150157570A1 (en) 2015-06-11
JP2018184470A (ja) 2018-11-22
US20220087934A1 (en) 2022-03-24
US20230031648A1 (en) 2023-02-02
US20200345639A1 (en) 2020-11-05
ES2821502T3 (es) 2021-04-26
JP6382801B2 (ja) 2018-08-29
EP3782606A1 (en) 2021-02-24
HUE051761T2 (hu) 2021-03-29
LT2861214T (lt) 2020-12-28
EP2861214A1 (en) 2015-04-22
AU2013276565B2 (en) 2018-12-20
HK1210018A1 (en) 2016-04-15
CN104602672A (zh) 2015-05-06
SMT202000584T1 (it) 2020-11-10
RU2018138012A (ru) 2019-03-21
RU2014148284A (ru) 2016-08-10
AU2019201776A1 (en) 2019-04-04
AU2013276565A1 (en) 2014-12-18
JP6656321B2 (ja) 2020-03-04

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