RS60951B1 - Lipozomi prilagođeni za lečenje bakterijskih infekcija - Google Patents

Lipozomi prilagođeni za lečenje bakterijskih infekcija

Info

Publication number
RS60951B1
RS60951B1 RS20201252A RSP20201252A RS60951B1 RS 60951 B1 RS60951 B1 RS 60951B1 RS 20201252 A RS20201252 A RS 20201252A RS P20201252 A RSP20201252 A RS P20201252A RS 60951 B1 RS60951 B1 RS 60951B1
Authority
RS
Serbia
Prior art keywords
treatment
bacterial infections
liposomes
tailored
tailored liposomes
Prior art date
Application number
RS20201252A
Other languages
English (en)
Inventor
Eduard Babiychuk
Annette Draeger
Original Assignee
Univ Bern
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Bern filed Critical Univ Bern
Publication of RS60951B1 publication Critical patent/RS60951B1/sr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Liposomes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A61K31/569Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone substituted in position 17 alpha, e.g. ethisterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/683Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
    • A61K31/688Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols both hydroxy compounds having nitrogen atoms, e.g. sphingomyelins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Liposomes
    • A61K9/1271Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • A61P39/02Antidotes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Toxicology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Dermatology (AREA)
  • Pulmonology (AREA)
  • Oncology (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
RS20201252A 2012-06-14 2013-06-13 Lipozomi prilagođeni za lečenje bakterijskih infekcija RS60951B1 (sr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP12171924 2012-06-14
EP13153039 2013-01-29
PCT/EP2013/062207 WO2013186286A1 (en) 2012-06-14 2013-06-13 Tailored liposomes for the treatment of bacterial infections
EP13732388.7A EP2861214B1 (en) 2012-06-14 2013-06-13 Tailored liposomes for the treatment of bacterial infections

Publications (1)

Publication Number Publication Date
RS60951B1 true RS60951B1 (sr) 2020-11-30

Family

ID=48703423

Family Applications (1)

Application Number Title Priority Date Filing Date
RS20201252A RS60951B1 (sr) 2012-06-14 2013-06-13 Lipozomi prilagođeni za lečenje bakterijskih infekcija

Country Status (19)

Country Link
US (4) US10744089B2 (sr)
EP (2) EP3782606A1 (sr)
JP (2) JP6382801B2 (sr)
CN (2) CN104602672B (sr)
AU (2) AU2013276565B2 (sr)
BR (1) BR112014031278B1 (sr)
CA (1) CA2875470C (sr)
CY (1) CY1123337T1 (sr)
DK (1) DK2861214T3 (sr)
ES (1) ES2821502T3 (sr)
HK (1) HK1210018A1 (sr)
HR (1) HRP20201761T1 (sr)
HU (1) HUE051761T2 (sr)
LT (1) LT2861214T (sr)
PL (1) PL2861214T3 (sr)
RS (1) RS60951B1 (sr)
RU (1) RU2672106C2 (sr)
SI (1) SI2861214T1 (sr)
WO (1) WO2013186286A1 (sr)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUE051761T2 (hu) * 2012-06-14 2021-03-29 Univ Bern Testreszabott liposzómák bakteriális fertõzések kezelésére
US20170000875A1 (en) 2013-12-02 2017-01-05 Arytha Biosciences, Llc Toxoid preparation and uses thereof
US10739353B2 (en) * 2014-12-31 2020-08-11 Signpath Pharma, Inc. Suppression of cytokine release and cytokine storm
WO2017115358A1 (en) 2015-12-28 2017-07-06 Mb Biotech Ltd. Liposomes for treatment of an autoimmune disease
EP3440187A1 (en) * 2016-04-07 2019-02-13 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Francisella lipids as broad anti-inflammatory therapeutics and associated methods of use
LT3471732T (lt) 2016-06-16 2020-09-10 Combioxin Sa Liposomos, skirtos virusinių infekcijų gydymui
EP3589278A1 (en) * 2017-03-02 2020-01-08 Combioxin SA Liposomes for inhibiting biofilm formation
US11344497B1 (en) * 2017-12-08 2022-05-31 Quicksilver Scientific, Inc. Mitochondrial performance enhancement nanoemulsion
EP4338743A1 (en) * 2018-04-17 2024-03-20 Combioxin SA Treatment of pneumonia
CN111971068A (zh) * 2018-04-20 2020-11-20 康柏辛股份有限公司 败血症和败血性休克的治疗
CN111214439B (zh) * 2018-11-23 2023-02-10 复旦大学 一种具有细菌成孔毒素吸附性能的纳米药物系统及其用途
CA3189374A1 (en) * 2020-07-31 2022-02-03 Signpath Pharma, Inc. Suppression of cytokine release and cytokine storm
CN115054577A (zh) * 2022-05-17 2022-09-16 温州医科大学附属第二医院(温州医科大学附属育英儿童医院) 纳米解毒剂及其在中和mrsa穿孔毒素的应用

Family Cites Families (21)

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AU6428890A (en) * 1989-09-12 1991-04-18 Regents Of The University Of California, The Therapeutic peptides and proteins
NL9000207A (sr) * 1990-01-29 1991-08-16 Duphar Int Res
WO1993004672A1 (en) * 1991-09-11 1993-03-18 Pitman-Moore, Inc. Method for enhancing the immune system in a host employing liposome-encapsulated polypeptides
US5543152A (en) * 1994-06-20 1996-08-06 Inex Pharmaceuticals Corporation Sphingosomes for enhanced drug delivery
US5741516A (en) * 1994-06-20 1998-04-21 Inex Pharmaceuticals Corporation Sphingosomes for enhanced drug delivery
US6726925B1 (en) * 1998-06-18 2004-04-27 Duke University Temperature-sensitive liposomal formulation
US8110217B2 (en) * 2001-08-13 2012-02-07 University Of Pittsburgh Sphingomyelin liposomes for the treatment of hyperactive bladder disorders
US8518437B2 (en) * 2001-11-13 2013-08-27 Celator Pharmaceuticals, Inc. Lipid carrier compositions with enhanced blood stability
CA2368656A1 (en) * 2002-01-21 2003-07-21 Vasogen Ireland Limited Receptor-ligand pairing for anti-inflammatory response
CA2490062A1 (en) * 2002-05-23 2003-12-04 Activbiotics, Inc. Methods of treating bacterial infections and diseases associated therewith
CA2506746A1 (en) * 2002-11-26 2004-06-10 Gilead Sciences, Inc. Method of drug loading in liposomes by gradient
WO2004087097A2 (en) * 2003-03-31 2004-10-14 Yissum Research Development Company Of The Hebrew University Of Jerusalem Stable liposomes or micelles comprising a sphinolipid and a peg-lipopolymer
WO2006052767A2 (en) * 2004-11-05 2006-05-18 Inex Pharmaceuticals Corporation Compositions and methods for stabilizing liposomal camptothecin formulations
CN1939340A (zh) * 2005-09-29 2007-04-04 中国人民解放军军事医学科学院毒物药物研究所 脂质体制剂
WO2008039989A2 (en) * 2006-09-28 2008-04-03 Transave, Inc. Formulations of dnase and methods of use thereof
WO2008058156A2 (en) * 2006-11-06 2008-05-15 Jina Pharmaceuticals Inc. Guggulphospholipid methods and compositions
CN1994279A (zh) * 2006-12-31 2007-07-11 西安力邦医药科技有限责任公司 注射用盐酸伊立替康脂质体的制备方法
CN101623262B (zh) * 2009-08-24 2011-02-02 海南美大制药有限公司 一种五水头孢唑啉钠前体脂质体制剂
US10272040B2 (en) * 2010-08-12 2019-04-30 Nanyang Technological University Liposomal formulation for ocular drug delivery
CN102327220B (zh) * 2011-07-14 2012-09-26 海南灵康制药有限公司 一种氯雷他定脂质体固体制剂
HUE051761T2 (hu) * 2012-06-14 2021-03-29 Univ Bern Testreszabott liposzómák bakteriális fertõzések kezelésére

Also Published As

Publication number Publication date
EP2861214A1 (en) 2015-04-22
JP6382801B2 (ja) 2018-08-29
BR112014031278A2 (pt) 2017-06-27
ES2821502T3 (es) 2021-04-26
US20200345639A1 (en) 2020-11-05
EP2861214B1 (en) 2020-08-05
AU2019201776B2 (en) 2020-11-12
HK1210018A1 (en) 2016-04-15
AU2013276565B2 (en) 2018-12-20
CA2875470A1 (en) 2013-12-19
CN104602672A (zh) 2015-05-06
US10744089B2 (en) 2020-08-18
RU2018138012A (ru) 2019-03-21
HRP20201761T1 (hr) 2020-12-25
CN109549925B (zh) 2022-06-17
US20220087934A1 (en) 2022-03-24
PL2861214T3 (pl) 2021-02-08
US20230031648A1 (en) 2023-02-02
AU2013276565A1 (en) 2014-12-18
WO2013186286A1 (en) 2013-12-19
HUE051761T2 (hu) 2021-03-29
CN109549925A (zh) 2019-04-02
LT2861214T (lt) 2020-12-28
CA2875470C (en) 2021-01-12
EP3782606A1 (en) 2021-02-24
DK2861214T3 (da) 2020-10-12
US20150157570A1 (en) 2015-06-11
BR112014031278B1 (pt) 2020-12-01
SI2861214T1 (sl) 2021-01-29
CN104602672B (zh) 2018-12-25
JP2018184470A (ja) 2018-11-22
RU2014148284A (ru) 2016-08-10
JP6656321B2 (ja) 2020-03-04
JP2015519383A (ja) 2015-07-09
RU2672106C2 (ru) 2018-11-12
CY1123337T1 (el) 2021-12-31
AU2019201776A1 (en) 2019-04-04

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