SI2342197T1 - Radioaktivno oznaäśeni inhibitorji prenaĺ alca glicina 1 - Google Patents

Radioaktivno oznaäśeni inhibitorji prenaĺ alca glicina 1

Info

Publication number
SI2342197T1
SI2342197T1 SI200930547T SI200930547T SI2342197T1 SI 2342197 T1 SI2342197 T1 SI 2342197T1 SI 200930547 T SI200930547 T SI 200930547T SI 200930547 T SI200930547 T SI 200930547T SI 2342197 T1 SI2342197 T1 SI 2342197T1
Authority
SI
Slovenia
Prior art keywords
transporter
glycine
radiolabelled
inhibitors
radiolabelled inhibitors
Prior art date
Application number
SI200930547T
Other languages
English (en)
Inventor
Daniela Alberati
Edilio Maurizio Borroni
Thomas Hartung
Roger Norcross
Emmanuel Pinard
Original Assignee
F. Hoffmann-La Roche Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F. Hoffmann-La Roche Ag filed Critical F. Hoffmann-La Roche Ag
Publication of SI2342197T1 publication Critical patent/SI2342197T1/sl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/10—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/60—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances involving radioactive labelled substances

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Pain & Pain Management (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • Food Science & Technology (AREA)
  • Optics & Photonics (AREA)
  • Hospice & Palliative Care (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SI200930547T 2008-11-04 2009-10-26 Radioaktivno oznaäśeni inhibitorji prenaĺ alca glicina 1 SI2342197T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP08168229 2008-11-04
EP09737459A EP2342197B1 (en) 2008-11-04 2009-10-26 Radiolabelled inhibitors of the glycine 1 transporter
PCT/EP2009/064033 WO2010052143A1 (en) 2008-11-04 2009-10-26 Radiolabelled inhibitors of the glycine 1 transporter

Publications (1)

Publication Number Publication Date
SI2342197T1 true SI2342197T1 (sl) 2013-05-31

Family

ID=41402176

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200930547T SI2342197T1 (sl) 2008-11-04 2009-10-26 Radioaktivno oznaäśeni inhibitorji prenaĺ alca glicina 1

Country Status (21)

Country Link
US (1) US8153679B2 (sl)
EP (1) EP2342197B1 (sl)
JP (1) JP5543477B2 (sl)
KR (1) KR101307671B1 (sl)
CN (1) CN102186844B (sl)
AR (1) AR074084A1 (sl)
AU (1) AU2009312891B2 (sl)
BR (1) BRPI0921795B8 (sl)
CA (1) CA2739869C (sl)
CL (1) CL2011000982A1 (sl)
DK (1) DK2342197T3 (sl)
ES (1) ES2401221T3 (sl)
IL (1) IL211804A (sl)
MX (1) MX2011004350A (sl)
PE (1) PE20110434A1 (sl)
PL (1) PL2342197T3 (sl)
RU (1) RU2512529C2 (sl)
SI (1) SI2342197T1 (sl)
TW (1) TWI449537B (sl)
WO (1) WO2010052143A1 (sl)
ZA (1) ZA201102521B (sl)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5618047B2 (ja) * 2010-01-29 2014-11-05 国立大学法人千葉大学 ポジトロン断層撮影法およびポジトロン放出化合物

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1656361T3 (da) 2003-08-11 2008-05-05 Hoffmann La Roche Piperazin med OR-substitueret phenylgruppe og anvendelse deraf som GLYT1-inhibitorer
DE602006010665D1 (en) * 2005-02-07 2010-01-07 Hoffmann La Roche Heterocyclsche substituierte phenylmethanone als inhibitoren des glycintransporters 1
ES2382818T3 (es) * 2005-09-29 2012-06-13 Merck Sharp & Dohme Corp. Inhibidores de transportadores glicina radiomarcados

Also Published As

Publication number Publication date
TWI449537B (zh) 2014-08-21
BRPI0921795B1 (pt) 2020-10-20
US20100111862A1 (en) 2010-05-06
RU2011118230A (ru) 2012-12-20
BRPI0921795A2 (pt) 2016-01-12
ZA201102521B (en) 2012-09-29
CN102186844A (zh) 2011-09-14
KR101307671B1 (ko) 2013-09-12
JP5543477B2 (ja) 2014-07-09
CA2739869C (en) 2016-09-27
AR074084A1 (es) 2010-12-22
PL2342197T3 (pl) 2013-06-28
AU2009312891B2 (en) 2013-07-11
CN102186844B (zh) 2014-08-13
PE20110434A1 (es) 2011-07-01
EP2342197B1 (en) 2013-01-16
US8153679B2 (en) 2012-04-10
MX2011004350A (es) 2011-05-23
BRPI0921795B8 (pt) 2021-07-27
CL2011000982A1 (es) 2012-02-03
ES2401221T3 (es) 2013-04-17
EP2342197A1 (en) 2011-07-13
DK2342197T3 (da) 2013-02-18
WO2010052143A1 (en) 2010-05-14
RU2512529C2 (ru) 2014-04-10
KR20110063861A (ko) 2011-06-14
AU2009312891A1 (en) 2010-05-14
IL211804A0 (en) 2011-06-30
TW201019964A (en) 2010-06-01
IL211804A (en) 2013-11-28
CA2739869A1 (en) 2011-05-14
JP2012507486A (ja) 2012-03-29

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