SI21270A - Kristalne oblike olanzapina in postopki za njihovo pripravo - Google Patents

Kristalne oblike olanzapina in postopki za njihovo pripravo Download PDF

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Publication number
SI21270A
SI21270A SI200200175A SI200200175A SI21270A SI 21270 A SI21270 A SI 21270A SI 200200175 A SI200200175 A SI 200200175A SI 200200175 A SI200200175 A SI 200200175A SI 21270 A SI21270 A SI 21270A
Authority
SI
Slovenia
Prior art keywords
olanzapine
solvate
methylene chloride
solvent
acetonitrile
Prior art date
Application number
SI200200175A
Other languages
English (en)
Slovenian (sl)
Inventor
- Jordan Berta Kotar
Franc Vre�er
Marija Gr�man
Original Assignee
Krka, Tovarna Zdravil, D.D., Novo Mesto
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Krka, Tovarna Zdravil, D.D., Novo Mesto filed Critical Krka, Tovarna Zdravil, D.D., Novo Mesto
Priority to SI200200175A priority Critical patent/SI21270A/sl
Priority to PL373845A priority patent/PL217081B1/pl
Priority to YU20050023A priority patent/RS53474B/en
Priority to PCT/SI2003/000024 priority patent/WO2004006933A2/en
Priority to AU2003256242A priority patent/AU2003256242A1/en
Priority to UAA200501303A priority patent/UA83633C2/ru
Priority to EA200500188A priority patent/EA008055B1/ru
Priority to CA002493370A priority patent/CA2493370C/en
Priority to SI200332341T priority patent/SI1551414T1/sl
Priority to EP03764287.3A priority patent/EP1551414B1/de
Priority to US10/521,646 priority patent/US7745429B2/en
Publication of SI21270A publication Critical patent/SI21270A/sl
Priority to HRP20050039AA priority patent/HRP20050039B1/hr
Priority to NO20050720A priority patent/NO20050720L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SI200200175A 2002-07-15 2002-07-15 Kristalne oblike olanzapina in postopki za njihovo pripravo SI21270A (sl)

Priority Applications (13)

Application Number Priority Date Filing Date Title
SI200200175A SI21270A (sl) 2002-07-15 2002-07-15 Kristalne oblike olanzapina in postopki za njihovo pripravo
UAA200501303A UA83633C2 (ru) 2002-07-15 2003-07-14 Способ получения формы и оланзапина, сольваты оланзапина и их применение в получении безводных форм оланзапина
YU20050023A RS53474B (en) 2002-07-15 2003-07-14 PROCEDURE FOR OBTAINING CRYSTAL FORM AND OLANZAPINE
PCT/SI2003/000024 WO2004006933A2 (en) 2002-07-15 2003-07-14 Crystal forms of olanzapine and processes for their preparation
AU2003256242A AU2003256242A1 (en) 2002-07-15 2003-07-14 Crystal forms of olanzapine and processes for their preparation
PL373845A PL217081B1 (pl) 2002-07-15 2003-07-14 Sposób otrzymywania formy I olanzapiny, solwat olanzapiny z 2-propanolem oraz solwaty olanzapiny z chlorkiem metylenu
EA200500188A EA008055B1 (ru) 2002-07-15 2003-07-14 Кристаллические формы оланзапина и способы их получения
CA002493370A CA2493370C (en) 2002-07-15 2003-07-14 Crystal forms of olanzapine and processes for their preparation
SI200332341T SI1551414T1 (sl) 2002-07-15 2003-07-14 Postopek za pripravo kristalne oblike I olanzapina
EP03764287.3A EP1551414B1 (de) 2002-07-15 2003-07-14 Verfahren zur Herstellung der kristallinen Form I von Olanzapine
US10/521,646 US7745429B2 (en) 2002-07-15 2003-07-14 Crystal forms of olanzapine and processes for their preparation
HRP20050039AA HRP20050039B1 (hr) 2002-07-15 2005-01-14 Kristalne forme olanzapina i postupci njihove priprave
NO20050720A NO20050720L (no) 2002-07-15 2005-02-10 Krystallformer av olanzapin og fremgangsmate for deres fremstilling

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SI200200175A SI21270A (sl) 2002-07-15 2002-07-15 Kristalne oblike olanzapina in postopki za njihovo pripravo

Publications (1)

Publication Number Publication Date
SI21270A true SI21270A (sl) 2004-02-29

Family

ID=30113490

Family Applications (2)

Application Number Title Priority Date Filing Date
SI200200175A SI21270A (sl) 2002-07-15 2002-07-15 Kristalne oblike olanzapina in postopki za njihovo pripravo
SI200332341T SI1551414T1 (sl) 2002-07-15 2003-07-14 Postopek za pripravo kristalne oblike I olanzapina

Family Applications After (1)

Application Number Title Priority Date Filing Date
SI200332341T SI1551414T1 (sl) 2002-07-15 2003-07-14 Postopek za pripravo kristalne oblike I olanzapina

Country Status (12)

Country Link
US (1) US7745429B2 (de)
EP (1) EP1551414B1 (de)
AU (1) AU2003256242A1 (de)
CA (1) CA2493370C (de)
EA (1) EA008055B1 (de)
HR (1) HRP20050039B1 (de)
NO (1) NO20050720L (de)
PL (1) PL217081B1 (de)
RS (1) RS53474B (de)
SI (2) SI21270A (de)
UA (1) UA83633C2 (de)
WO (1) WO2004006933A2 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL202856B1 (pl) * 2002-12-20 2009-07-31 Adamed Spo & Lstrok Ka Z Ogran Sposób otrzymywania farmaceutycznie czystej polimorficznej postaci I olanzapiny
EP1575962A1 (de) * 2002-12-24 2005-09-21 Teva Pharmaceutical Industries Limited Neue kristallformen von olanzapin, verfahren zu deren herstellung und verfahren zur herstellung bekannter kristallformen von olanzapin
AR047460A1 (es) * 2004-01-27 2006-01-18 Synthon Bv Proceso para la fabricacion de acetato de 2-metil-4-(4-metil-1-piperazinil)-10h-tieno[2,3-b][1,5]benzodiazepina (acetato de olanzapina)
EP1709053B1 (de) 2004-01-27 2011-04-06 Synthon B.V. Stabile salze von olanzapin
WO2005085256A1 (en) * 2004-03-08 2005-09-15 Krka, Tovarna Zdravil, D.D., Novo Mesto Isopropanol water solvate of olanzapine
ES2253091B1 (es) * 2004-07-27 2007-02-01 Inke, S.A. Solvato mixto de olanzapina, procedimiento para su obtencion y procedimiento de obtencion de la forma i de olanzapina a partir del mismo.
GB0522473D0 (en) 2005-11-03 2005-12-14 Actavis Group A pharmaceutical formulation
US7834176B2 (en) * 2006-01-26 2010-11-16 Sandoz Ag Polymorph E of Olanzapine and preparation of anhydrous non-solvated crystalline polymorphic Form I of 2-methyl-4(4-methyl-1-piperazinyl)-10H-thieno[2,3-b][1,5] benzodiazepine (Olanzapine Form I) from the polymorphic Olanzapine Form E

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU629879A3 (ru) 1974-11-26 1978-10-25 Лилли Индастриз Лимитед, (Фирма) Способ получени тиено(1,5) бензодиазепинов или их солей
US5229382A (en) 1990-04-25 1993-07-20 Lilly Industries Limited 2-methyl-thieno-benzodiazepine
EG24221A (en) 1995-03-24 2008-11-10 Lilly Co Eli Process for preparing olanzapine
CR5278A (es) * 1995-03-24 1996-07-04 Lilly Co Eli Formulacion oral de 2-metil-tieno-benzodiacepina
US5631250A (en) * 1995-03-24 1997-05-20 Eli Lilly And Company Process and solvate of 2-methyl-thieno-benzodiazepine
EG23659A (en) 1995-03-24 2007-03-26 Lilly Co Eli Process and crystal forms of methyl-thieno-benzodiazepine
US5776928A (en) * 1995-04-21 1998-07-07 Eli Lilly And Company Method for treating dyskinesias with olanzapine
US6506746B2 (en) * 1995-05-30 2003-01-14 Eli Lilly And Company Method for treating cognitive dysfunction
AU720366B2 (en) 1996-09-23 2000-06-01 Eli Lilly And Company Olanzapine dihydrate D
ZA978515B (en) 1996-09-23 1999-03-23 Lilly Co Eli Intermediates and process for preparing olanzapine
CA2304472A1 (en) * 1997-09-30 1999-04-08 Pierre Van Tran Method for treating sexual dysfunction
PT1246827E (pt) * 1999-12-28 2005-08-31 Cipla Ltd Novas formas polimerficas da olanzapina
WO2002018390A1 (en) 2000-08-31 2002-03-07 Dr. Reddy's Laboratories Ltd. Process for preparation of hydrates of olanzapine and their conversion into crystalline forms of olanzapine

Also Published As

Publication number Publication date
RS20050023A (en) 2007-06-04
HRP20050039A2 (en) 2005-08-31
EA008055B1 (ru) 2007-02-27
HRP20050039B1 (hr) 2014-10-10
AU2003256242A1 (en) 2004-02-02
NO20050720L (no) 2005-02-10
SI1551414T1 (sl) 2014-04-30
CA2493370A1 (en) 2004-01-22
RS53474B (en) 2014-12-31
WO2004006933A3 (en) 2004-04-01
EP1551414B1 (de) 2013-11-27
PL217081B1 (pl) 2014-06-30
US7745429B2 (en) 2010-06-29
EP1551414A2 (de) 2005-07-13
CA2493370C (en) 2009-09-29
US20060040920A1 (en) 2006-02-23
UA83633C2 (ru) 2008-08-11
PL373845A1 (en) 2005-09-19
EA200500188A1 (ru) 2005-06-30
WO2004006933A2 (en) 2004-01-22

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Effective date: 20070328