SI1551414T1 - Postopek za pripravo kristalne oblike I olanzapina - Google Patents

Postopek za pripravo kristalne oblike I olanzapina

Info

Publication number
SI1551414T1
SI1551414T1 SI200332341T SI200332341T SI1551414T1 SI 1551414 T1 SI1551414 T1 SI 1551414T1 SI 200332341 T SI200332341 T SI 200332341T SI 200332341 T SI200332341 T SI 200332341T SI 1551414 T1 SI1551414 T1 SI 1551414T1
Authority
SI
Slovenia
Prior art keywords
olanzapine
preparing
crystal form
crystal
Prior art date
Application number
SI200332341T
Other languages
English (en)
Inventor
Jordan Berta Kotar
Franc Vrecer
Marija Grcman
Original Assignee
Krka, D.D., Novo Mesto
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Krka, D.D., Novo Mesto filed Critical Krka, D.D., Novo Mesto
Publication of SI1551414T1 publication Critical patent/SI1551414T1/sl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SI200332341T 2002-07-15 2003-07-14 Postopek za pripravo kristalne oblike I olanzapina SI1551414T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SI200200175A SI21270A (sl) 2002-07-15 2002-07-15 Kristalne oblike olanzapina in postopki za njihovo pripravo
PCT/SI2003/000024 WO2004006933A2 (en) 2002-07-15 2003-07-14 Crystal forms of olanzapine and processes for their preparation
EP03764287.3A EP1551414B1 (en) 2002-07-15 2003-07-14 Process for preparing the crystal form I of olanzapine

Publications (1)

Publication Number Publication Date
SI1551414T1 true SI1551414T1 (sl) 2014-04-30

Family

ID=30113490

Family Applications (2)

Application Number Title Priority Date Filing Date
SI200200175A SI21270A (sl) 2002-07-15 2002-07-15 Kristalne oblike olanzapina in postopki za njihovo pripravo
SI200332341T SI1551414T1 (sl) 2002-07-15 2003-07-14 Postopek za pripravo kristalne oblike I olanzapina

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SI200200175A SI21270A (sl) 2002-07-15 2002-07-15 Kristalne oblike olanzapina in postopki za njihovo pripravo

Country Status (12)

Country Link
US (1) US7745429B2 (sl)
EP (1) EP1551414B1 (sl)
AU (1) AU2003256242A1 (sl)
CA (1) CA2493370C (sl)
EA (1) EA008055B1 (sl)
HR (1) HRP20050039B1 (sl)
NO (1) NO20050720L (sl)
PL (1) PL217081B1 (sl)
RS (1) RS53474B (sl)
SI (2) SI21270A (sl)
UA (1) UA83633C2 (sl)
WO (1) WO2004006933A2 (sl)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL202856B1 (pl) * 2002-12-20 2009-07-31 Adamed Spo & Lstrok Ka Z Ogran Sposób otrzymywania farmaceutycznie czystej polimorficznej postaci I olanzapiny
AU2003300324A1 (en) * 2002-12-24 2004-07-22 Teva Pharmaceutical Industries Ltd. Novel crystal forms of olanzapine, methods for their preparation and method for the preparation of known olanzapine crystal forms
AR047459A1 (es) 2004-01-27 2006-01-18 Synthon Bv Sales estables de 2-metil-4-(4-metil-1-piperazinil)-10h-tieno[2,3-b][1,5]benzodiazepina (olanzapina)
WO2005070939A1 (en) * 2004-01-27 2005-08-04 Synthon B.V. Synthesis of olanzapine and intermediates thereof
US7906642B2 (en) * 2004-03-08 2011-03-15 Krka, Tovarna Zdravil, D.D. Isopropanol water solvate of olanzapine
ES2253091B1 (es) 2004-07-27 2007-02-01 Inke, S.A. Solvato mixto de olanzapina, procedimiento para su obtencion y procedimiento de obtencion de la forma i de olanzapina a partir del mismo.
GB0522473D0 (en) 2005-11-03 2005-12-14 Actavis Group A pharmaceutical formulation
US7834176B2 (en) * 2006-01-26 2010-11-16 Sandoz Ag Polymorph E of Olanzapine and preparation of anhydrous non-solvated crystalline polymorphic Form I of 2-methyl-4(4-methyl-1-piperazinyl)-10H-thieno[2,3-b][1,5] benzodiazepine (Olanzapine Form I) from the polymorphic Olanzapine Form E

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU629879A3 (ru) 1974-11-26 1978-10-25 Лилли Индастриз Лимитед, (Фирма) Способ получени тиено(1,5) бензодиазепинов или их солей
US5229382A (en) 1990-04-25 1993-07-20 Lilly Industries Limited 2-methyl-thieno-benzodiazepine
US5631250A (en) * 1995-03-24 1997-05-20 Eli Lilly And Company Process and solvate of 2-methyl-thieno-benzodiazepine
EG24221A (en) 1995-03-24 2008-11-10 Lilly Co Eli Process for preparing olanzapine
CR5278A (es) * 1995-03-24 1996-07-04 Lilly Co Eli Formulacion oral de 2-metil-tieno-benzodiacepina
EG23659A (en) 1995-03-24 2007-03-26 Lilly Co Eli Process and crystal forms of methyl-thieno-benzodiazepine
US5776928A (en) * 1995-04-21 1998-07-07 Eli Lilly And Company Method for treating dyskinesias with olanzapine
US6506746B2 (en) * 1995-05-30 2003-01-14 Eli Lilly And Company Method for treating cognitive dysfunction
ZA978515B (en) 1996-09-23 1999-03-23 Lilly Co Eli Intermediates and process for preparing olanzapine
BR9711541A (pt) 1996-09-23 1999-08-24 Lilly Co Eli Dihidrato d de olanzapina
AU9583498A (en) * 1997-09-30 1999-04-23 Eli Lilly And Company Method for treating sexual dysfunction
AU779452B2 (en) * 1999-12-28 2005-01-27 Cipla Limited New polymorphic forms of olanzapine
AU2001243475A1 (en) 2000-08-31 2002-03-13 Dr. Reddy's Laboratories Ltd. Process for preparation of hydrates of olanzapine and their conversion into crystalline forms of olanzapine

Also Published As

Publication number Publication date
CA2493370A1 (en) 2004-01-22
US7745429B2 (en) 2010-06-29
HRP20050039A2 (en) 2005-08-31
UA83633C2 (ru) 2008-08-11
WO2004006933A3 (en) 2004-04-01
NO20050720L (no) 2005-02-10
RS53474B (en) 2014-12-31
EA008055B1 (ru) 2007-02-27
HRP20050039B1 (hr) 2014-10-10
PL217081B1 (pl) 2014-06-30
EP1551414A2 (en) 2005-07-13
SI21270A (sl) 2004-02-29
WO2004006933A2 (en) 2004-01-22
RS20050023A (en) 2007-06-04
EP1551414B1 (en) 2013-11-27
CA2493370C (en) 2009-09-29
PL373845A1 (en) 2005-09-19
US20060040920A1 (en) 2006-02-23
EA200500188A1 (ru) 2005-06-30
AU2003256242A1 (en) 2004-02-02

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