SI20743A - Novi trombinski inhibitorji - Google Patents

Novi trombinski inhibitorji Download PDF

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Publication number
SI20743A
SI20743A SI200000326A SI200000326A SI20743A SI 20743 A SI20743 A SI 20743A SI 200000326 A SI200000326 A SI 200000326A SI 200000326 A SI200000326 A SI 200000326A SI 20743 A SI20743 A SI 20743A
Authority
SI
Slovenia
Prior art keywords
formula
alkyl
compound
same meaning
compounds
Prior art date
Application number
SI200000326A
Other languages
English (en)
Slovenian (sl)
Inventor
Uro� Urleb
Anamarija Zega
Original Assignee
Univerza V Ljubljani,
Lek, tovarna farmacevtskih in kemi�nih izdelkov d.d.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univerza V Ljubljani,, Lek, tovarna farmacevtskih in kemi�nih izdelkov d.d. filed Critical Univerza V Ljubljani,
Priority to SI200000326A priority Critical patent/SI20743A/sl
Priority to DE60109498T priority patent/DE60109498T2/de
Priority to PCT/IB2001/002600 priority patent/WO2002051824A1/fr
Priority to JP2002552919A priority patent/JP4390453B2/ja
Priority to EP01272199A priority patent/EP1355894B1/fr
Priority to DK01272199T priority patent/DK1355894T3/da
Priority to PT01272199T priority patent/PT1355894E/pt
Priority to ES01272199T priority patent/ES2240345T3/es
Priority to AT01272199T priority patent/ATE291016T1/de
Priority to US10/433,358 priority patent/US7285547B2/en
Publication of SI20743A publication Critical patent/SI20743A/sl
Priority to US11/854,532 priority patent/US20080004256A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/20—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
    • C07D295/215—Radicals derived from nitrogen analogues of carbonic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/48—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups having nitrogen atoms of sulfonamide groups further bound to another hetero atom
    • C07C311/49—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups having nitrogen atoms of sulfonamide groups further bound to another hetero atom to nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
SI200000326A 2000-12-22 2000-12-22 Novi trombinski inhibitorji SI20743A (sl)

Priority Applications (11)

Application Number Priority Date Filing Date Title
SI200000326A SI20743A (sl) 2000-12-22 2000-12-22 Novi trombinski inhibitorji
DK01272199T DK1355894T3 (da) 2000-12-22 2001-12-20 Amidinophenylalaninderivater som thrombininhibitorer
PCT/IB2001/002600 WO2002051824A1 (fr) 2000-12-22 2001-12-20 Derives d'amidinophenylalanine utiles en tant qu'inhibiteurs de la thrombine
JP2002552919A JP4390453B2 (ja) 2000-12-22 2001-12-20 トロンビン阻害物質としてのアミジノフェニルアラニン誘導体
EP01272199A EP1355894B1 (fr) 2000-12-22 2001-12-20 Derives d'amidinophenylalanine utiles en tant qu'inhibiteurs de la thrombine
DE60109498T DE60109498T2 (de) 2000-12-22 2001-12-20 Amidinophenylalaninderivate als thrombininhibitoren
PT01272199T PT1355894E (pt) 2000-12-22 2001-12-20 Derivados de amidinofenilalanina como inibidores de trombina
ES01272199T ES2240345T3 (es) 2000-12-22 2001-12-20 Derivados de amidinofenilalanina como inhibidores de trombina.
AT01272199T ATE291016T1 (de) 2000-12-22 2001-12-20 Amidinophenylalaninderivate als thrombininhibitoren
US10/433,358 US7285547B2 (en) 2000-12-22 2001-12-20 Amidinophenylalanine derivatives as thrombin inhibitors
US11/854,532 US20080004256A1 (en) 2000-12-22 2007-09-12 Amidinophenylalanine Derivatives as Thrombin Inhibitors

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SI200000326A SI20743A (sl) 2000-12-22 2000-12-22 Novi trombinski inhibitorji

Publications (1)

Publication Number Publication Date
SI20743A true SI20743A (sl) 2002-06-30

Family

ID=20432799

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200000326A SI20743A (sl) 2000-12-22 2000-12-22 Novi trombinski inhibitorji

Country Status (10)

Country Link
US (2) US7285547B2 (fr)
EP (1) EP1355894B1 (fr)
JP (1) JP4390453B2 (fr)
AT (1) ATE291016T1 (fr)
DE (1) DE60109498T2 (fr)
DK (1) DK1355894T3 (fr)
ES (1) ES2240345T3 (fr)
PT (1) PT1355894E (fr)
SI (1) SI20743A (fr)
WO (1) WO2002051824A1 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0507577D0 (en) 2005-04-14 2005-05-18 Novartis Ag Organic compounds
GB0523539D0 (en) * 2005-11-18 2005-12-28 Lek Tovarna Farmacevtskih New use of organic compounds

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9322976D0 (en) 1993-11-08 1994-01-05 Pfizer Ltd Therapeutic agents

Also Published As

Publication number Publication date
DE60109498D1 (en) 2005-04-21
ATE291016T1 (de) 2005-04-15
JP2004516317A (ja) 2004-06-03
EP1355894A1 (fr) 2003-10-29
US20040048851A1 (en) 2004-03-11
US7285547B2 (en) 2007-10-23
DE60109498T2 (de) 2006-04-13
US20080004256A1 (en) 2008-01-03
PT1355894E (pt) 2005-08-31
EP1355894B1 (fr) 2005-03-16
ES2240345T3 (es) 2005-10-16
JP4390453B2 (ja) 2009-12-24
DK1355894T3 (da) 2005-07-11
WO2002051824A1 (fr) 2002-07-04

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Legal Events

Date Code Title Description
IF Valid on the event date
OU01 Decison according to article 73(1) ipa 1992, publication of decision on fulfilment of conditions on patentability

Effective date: 20100115

KO00 Lapse of patent

Effective date: 20121126