DK1355894T3 - Amidinophenylalaninderivater som thrombininhibitorer - Google Patents

Amidinophenylalaninderivater som thrombininhibitorer

Info

Publication number
DK1355894T3
DK1355894T3 DK01272199T DK01272199T DK1355894T3 DK 1355894 T3 DK1355894 T3 DK 1355894T3 DK 01272199 T DK01272199 T DK 01272199T DK 01272199 T DK01272199 T DK 01272199T DK 1355894 T3 DK1355894 T3 DK 1355894T3
Authority
DK
Denmark
Prior art keywords
thrombin inhibitors
amidinophenylalanine derivatives
amidinophenylalanine
derivatives
compounds
Prior art date
Application number
DK01272199T
Other languages
English (en)
Inventor
Anamarija Zega
Bakija Alenka Trampus
Tomaz Solmajer
Gregor Mlinsek
Uros Urleb
Mojca Stegnar
Original Assignee
Univ Ljubljani
Lek Tovarna Farmacevtskih
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Ljubljani, Lek Tovarna Farmacevtskih filed Critical Univ Ljubljani
Application granted granted Critical
Publication of DK1355894T3 publication Critical patent/DK1355894T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/20Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
    • C07D295/215Radicals derived from nitrogen analogues of carbonic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/48Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups having nitrogen atoms of sulfonamide groups further bound to another hetero atom
    • C07C311/49Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups having nitrogen atoms of sulfonamide groups further bound to another hetero atom to nitrogen atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DK01272199T 2000-12-22 2001-12-20 Amidinophenylalaninderivater som thrombininhibitorer DK1355894T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SI200000326A SI20743A (sl) 2000-12-22 2000-12-22 Novi trombinski inhibitorji
PCT/IB2001/002600 WO2002051824A1 (en) 2000-12-22 2001-12-20 Amidinophenylalanine derivatives as thrombin inhibitors

Publications (1)

Publication Number Publication Date
DK1355894T3 true DK1355894T3 (da) 2005-07-11

Family

ID=20432799

Family Applications (1)

Application Number Title Priority Date Filing Date
DK01272199T DK1355894T3 (da) 2000-12-22 2001-12-20 Amidinophenylalaninderivater som thrombininhibitorer

Country Status (10)

Country Link
US (2) US7285547B2 (da)
EP (1) EP1355894B1 (da)
JP (1) JP4390453B2 (da)
AT (1) ATE291016T1 (da)
DE (1) DE60109498T2 (da)
DK (1) DK1355894T3 (da)
ES (1) ES2240345T3 (da)
PT (1) PT1355894E (da)
SI (1) SI20743A (da)
WO (1) WO2002051824A1 (da)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0507577D0 (en) 2005-04-14 2005-05-18 Novartis Ag Organic compounds
GB0523539D0 (en) * 2005-11-18 2005-12-28 Lek Tovarna Farmacevtskih New use of organic compounds

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9322976D0 (en) 1993-11-08 1994-01-05 Pfizer Ltd Therapeutic agents

Also Published As

Publication number Publication date
EP1355894A1 (en) 2003-10-29
JP4390453B2 (ja) 2009-12-24
SI20743A (sl) 2002-06-30
JP2004516317A (ja) 2004-06-03
US7285547B2 (en) 2007-10-23
US20040048851A1 (en) 2004-03-11
DE60109498D1 (en) 2005-04-21
US20080004256A1 (en) 2008-01-03
ES2240345T3 (es) 2005-10-16
WO2002051824A1 (en) 2002-07-04
ATE291016T1 (de) 2005-04-15
PT1355894E (pt) 2005-08-31
DE60109498T2 (de) 2006-04-13
EP1355894B1 (en) 2005-03-16

Similar Documents

Publication Publication Date Title
SE0202463D0 (sv) Novel compounds
DK1406876T3 (da) 2-anilinopyrimidinderivater som inhibitorer af cyclinafhængige kinaser
HUP0400636A2 (hu) Azetidinszármazékokat tartalmazó gyógyszerkészítmények, új azetidinszármazékok és előállításuk
SE9904738D0 (sv) Novel compounds
NO20051695L (no) Nye spirokondenserte kinazolinoner og deres anvendelse som fosfodiestereaseinbibitorer
NO20051259L (no) Biaryl-diazabicykloalkanamider som nikotinacetylcholinagonister
EE200300259A (et) Mandelhappe derivaadid, nende valmistamise meetod, nende kasutamine trombiini inhibiitoritena ja neid sisaldavad ravimkoostised
ATE273305T1 (de) Thrombin-inhibitoren
RS50140B (sr) Postupak za dobijanje perkihinina i njegova upotreba
SE9904505D0 (sv) Novel compounds
CY1108522T1 (el) Μεθοδος συνθεσης της περινδοπριλης και των φαρμακευτικως αποδεκτων αλατων της
NO20044731L (no) Kinolin- og isokinolinderivater fremgangsmate for fremstilling derav og anvendelse derav som betennelseshemmere
GEP20094676B (en) Piperidine compounds and pharmaceutical compositions containing them
IL173810A0 (en) Imidazopyridine derivatives and pharmaceutical compositions containing the same
NO20015172L (no) 1-metyl-erytromycin-derivater
SE0300908D0 (sv) Azaindole derivatives, preparations thereof, uses thereof and compositions containing them
UA86776C2 (ru) Производные бензимидазола, фармацевтическая композиция, которая их содержит, способ их получения и применение
IL173895A0 (en) Imidazopyridine derivatives and pharmaceutical compositions containing the same
WO2001081316A3 (en) Substituted phenyl farnesyltransferase inhibitors
DK1109560T3 (da) Som AICARFT-inhibitorer anvendelige forbindelser
SE0301699D0 (sv) Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof
MXPA04005484A (es) Procedimiento de preparacion de derivados de equinocandina.
MXPA02004441A (es) Derivados de isoxazol como inhibidores de la fosfodiesterasa.
MXPA04009421A (es) Compuestos de tiazol-2-ilimina como inhibidores de la pde-7.
EA200300272A1 (ru) Новые производные хиназолина, способ их получения и фармацевтические композиции, содержащие их