SI1919458T1 - Enterično obloženi cisteamin cistamin in njuniderivati - Google Patents
Enterično obloženi cisteamin cistamin in njuniderivatiInfo
- Publication number
- SI1919458T1 SI1919458T1 SI200731035T SI200731035T SI1919458T1 SI 1919458 T1 SI1919458 T1 SI 1919458T1 SI 200731035 T SI200731035 T SI 200731035T SI 200731035 T SI200731035 T SI 200731035T SI 1919458 T1 SI1919458 T1 SI 1919458T1
- Authority
- SI
- Slovenia
- Prior art keywords
- cystamine
- derivatives
- enterically coated
- coated cysteamine
- cysteamine
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/194—Carboxylic acids, e.g. valproic acid having two or more carboxyl groups, e.g. succinic, maleic or phthalic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/145—Amines having sulfur, e.g. thiurams (>N—C(S)—S—C(S)—N< and >N—C(S)—S—S—C(S)—N<), Sulfinylamines (—N=SO), Sulfonylamines (—N=SO2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
- A61K9/2846—Poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
- A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/2873—Proteins, e.g. gelatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/288—Compounds of unknown constitution, e.g. material from plants or animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
- A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
- A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
- A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5052—Proteins, e.g. albumin
- A61K9/5057—Gelatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5063—Compounds of unknown constitution, e.g. material from plants or animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Botany (AREA)
- Zoology (AREA)
- Psychology (AREA)
- Physiology (AREA)
- Nutrition Science (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Hematology (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US76271506P | 2006-01-27 | 2006-01-27 | |
PCT/US2007/002325 WO2007089670A2 (en) | 2006-01-27 | 2007-01-26 | Enterically coated cysteamine, cystamine and derivatives thereof |
EP07762690.1A EP1919458B3 (en) | 2006-01-27 | 2007-01-26 | Enterically coated cysteamine, cystamine and derivatives thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
SI1919458T1 true SI1919458T1 (sl) | 2012-11-30 |
Family
ID=38327943
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SI200731035T SI1919458T1 (sl) | 2006-01-27 | 2007-01-26 | Enterično obloženi cisteamin cistamin in njuniderivati |
SI200732147T SI2535044T1 (sl) | 2006-01-27 | 2007-01-26 | Cisteamin bitartrat in cistamin z enterično oblogo |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SI200732147T SI2535044T1 (sl) | 2006-01-27 | 2007-01-26 | Cisteamin bitartrat in cistamin z enterično oblogo |
Country Status (20)
Country | Link |
---|---|
US (15) | US8026284B2 (sl) |
EP (3) | EP3659588A1 (sl) |
AU (1) | AU2007210005C1 (sl) |
BR (1) | BRPI0707277B1 (sl) |
CA (1) | CA2640531C (sl) |
CY (1) | CY1122943T1 (sl) |
DK (2) | DK1919458T6 (sl) |
EA (2) | EA201600089A1 (sl) |
ES (2) | ES2388310T7 (sl) |
FR (1) | FR14C0018I1 (sl) |
HU (1) | HUE049307T2 (sl) |
IL (1) | IL193044A (sl) |
LT (1) | LT2535044T (sl) |
LU (1) | LU92389I2 (sl) |
MX (1) | MX2008009647A (sl) |
NL (1) | NL300649I2 (sl) |
PL (2) | PL1919458T6 (sl) |
PT (2) | PT2535044T (sl) |
SI (2) | SI1919458T1 (sl) |
WO (1) | WO2007089670A2 (sl) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EA201600089A1 (ru) | 2006-01-27 | 2017-01-30 | Те Риджентс Оф Те Юниверсити Оф Калифорния | Покрытые энтеросолюбильной оболочкой цистеамин и цистамин и их производные |
JP5583022B2 (ja) | 2007-11-30 | 2014-09-03 | ザ レジェンツ オブ ザ ユニヴァースティ オブ カリフォルニア | システアミン生成物を用いる非アルコール性脂肪性肝炎(nash)の治療方法 |
US9023798B2 (en) | 2009-07-24 | 2015-05-05 | The Regents Of The University Of Michigan | Cystinosin replacement factor |
US8815942B2 (en) | 2010-10-20 | 2014-08-26 | The Royal Institution For The Advancement Of Learning/Mcgill University | Combination therapy and uses thereof for treatment and prevention of parasitic infection and disease |
CA2732440C (en) * | 2011-02-23 | 2017-10-31 | Universite Laval | Cystamine analogues for the treatment of parkinson`s disease |
AU2011379972B2 (en) | 2011-10-26 | 2016-05-12 | Seattle Children's Research Institute | Cysteamine in the treatment of fibrotic disease |
US20140314841A1 (en) | 2013-04-19 | 2014-10-23 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Serv | Use of Cysteamine and Derivatives Thereof to Suppress Tumor Metastases |
TWI659209B (zh) * | 2013-06-17 | 2019-05-11 | 地平線罕見醫學製藥有限責任公司 | 分析半胱胺組合物的方法 |
TWI649100B (zh) | 2013-06-17 | 2019-02-01 | 地平線罕見醫學製藥有限責任公司 | 延遲釋放型半胱胺珠粒調配物,以及其製備及使用方法 |
EP4043011A1 (en) * | 2014-05-16 | 2022-08-17 | Children's Hospital Medical Center | Methods for assessing responsiveness to asthma treatment based on vnn-1 expression and promoter methylation |
TW201618760A (zh) * | 2014-11-05 | 2016-06-01 | 雷普特製藥有限公司 | 使用半胱胺組合物治療亨廷頓氏病之方法 |
JP2018525350A (ja) | 2015-07-02 | 2018-09-06 | ホライズン オルファン エルエルシー | Ado耐性システアミン類似体およびその使用 |
WO2017087532A1 (en) | 2015-11-16 | 2017-05-26 | The Regents Of The University Of California | Methods of treating non-alcoholic steatohepatitis (nash) using cysteamine compounds |
US10143665B2 (en) | 2015-11-17 | 2018-12-04 | Horizon Orphan Llc | Methods for storing cysteamine formulations and related methods of treatment |
CA3017797A1 (en) * | 2016-03-17 | 2017-09-21 | Thiogenesis Therapeutics, Inc. | Compositions for controlled release of cysteamine and systemic treatment of cysteamine sensitive disorders |
ITUA20161799A1 (it) * | 2016-03-18 | 2017-09-18 | Recordati Ind Chimica E Farmaceutica S P A | Composizione farmaceutica a rilascio prolungato comprendente cisteamina o un suo sale |
EP3308773A1 (en) | 2016-10-11 | 2018-04-18 | Recordati Industria Chimica E Farmaceutica SPA | Formulations of cysteamine and cysteamine derivatives |
WO2018093364A1 (en) * | 2016-11-16 | 2018-05-24 | The Regents Of The University Of California | Formulations of cysteamine and cystamine |
US10251850B2 (en) | 2017-01-11 | 2019-04-09 | Lupin Limited | Process for preparation of cysteamine bitartrate |
EP3684418A4 (en) | 2017-09-20 | 2021-06-16 | Thiogenesis Therapeutics, Inc. | TREATMENT METHODS FOR CYSTEAMINE SENSITIVE CONDITIONS |
EP3684309A4 (en) * | 2017-09-22 | 2021-06-09 | University of Florida Research Foundation | DEVICES AND METHODS FOR REDUCING CYSTINE CRYSTALS IN VIVO |
GB2581362A (en) | 2019-02-14 | 2020-08-19 | Univ Of Sunderland | Chemical synthesis |
EP3946298A4 (en) | 2019-03-26 | 2023-01-25 | The Regents of the University of California | SUBSTITUTED AMINO-THIOL AND AMINODISULFIDE COMPOUNDS AND THEIR USES |
WO2020220036A1 (en) * | 2019-04-25 | 2020-10-29 | Fremonta Corporation | Powered sampling device |
WO2022109198A1 (en) * | 2020-11-19 | 2022-05-27 | Birch Therapeutics, Inc. | Cystamine formulations and uses thereof |
Family Cites Families (38)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2809918A (en) | 1955-10-17 | 1957-10-15 | Victor M Hermelin | Sustained release pharmaceutical preparations |
DE2010416B2 (de) | 1970-03-05 | 1979-03-29 | Hoechst Ag, 6000 Frankfurt | Oral anwendbare Arzneiform mit Retardwirkung |
US4110441A (en) | 1974-04-29 | 1978-08-29 | Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt. | Gamma-l-glutamyl cholamine phosphate |
FR2471186A1 (fr) | 1979-12-10 | 1981-06-19 | Roussel Uclaf | Nouveaux comprimes a delitescence colique, ainsi que leur procede de preparation |
US4301146A (en) | 1980-07-29 | 1981-11-17 | G. D. Searle & Co. | Stabilization of 16-oxygenated prostanoic acid derivatives |
US4728512A (en) | 1985-05-06 | 1988-03-01 | American Home Products Corporation | Formulations providing three distinct releases |
US4794001A (en) | 1986-03-04 | 1988-12-27 | American Home Products Corporation | Formulations providing three distinct releases |
US4959306A (en) | 1986-11-28 | 1990-09-25 | Sclavo, Inc. | Labeling design for a binding assay reagent |
US5668117A (en) * | 1991-02-22 | 1997-09-16 | Shapiro; Howard K. | Methods of treating neurological diseases and etiologically related symptomology using carbonyl trapping agents in combination with previously known medicaments |
US5225202A (en) | 1991-09-30 | 1993-07-06 | E. R. Squibb & Sons, Inc. | Enteric coated pharmaceutical compositions |
US5639743A (en) * | 1992-11-13 | 1997-06-17 | University Of Georgia Research Foundation | Compositions and methods for treating exocrine gland atrophy |
CA2236344A1 (en) * | 1998-04-30 | 1999-10-30 | Hemosol Inc. | Hemoglobin-haptoglobin complexes |
UA69413C2 (uk) | 1998-05-22 | 2004-09-15 | Брістол-Майерс Сквібб Компані | Фармацевтична композиція, яка містить серцевину та ентеросолюбільну оболонку, фармацевтична композиція у вигляді сфероїдальних гранул, спосіб одержання сфероїдальних гранул та спосіб одержання фармацевтичної композиції |
US6794414B1 (en) * | 1998-06-17 | 2004-09-21 | Yeda Research And Development Co. Ltd. | Method and compositions for treating diseases mediated by transglutaminase activity |
UA73092C2 (uk) * | 1998-07-17 | 2005-06-15 | Брістол-Майерс Сквібб Компані | Таблетка з ентеросолюбільним покриттям і спосіб її приготування |
WO2001058708A1 (en) | 2000-02-14 | 2001-08-16 | Len Booysen | Stabilizer unit |
US20050004075A1 (en) | 2000-12-13 | 2005-01-06 | Walcom Animal Science (I.P.2) Limited | Composition for regulating animal growth, method of manufacture and use thereof |
CN1144585C (zh) * | 2000-12-13 | 2004-04-07 | 华扩达动物科学[I.P.2]有限公司 | 含有半胱胺或其盐类的促进动物快速生长的组合物及用途 |
GB2377874B (en) | 2001-07-23 | 2005-06-22 | Walcom Bio Chemicals Ind Ltd | Poultry feed and the use thereof |
US7449451B2 (en) * | 2001-08-29 | 2008-11-11 | Premier Micronutrient Corporation | Use of multiple antioxidant micronutrients as systemic biological radioprotective agents against potential ionizing radiation risks |
GB2379854B (en) * | 2001-09-19 | 2006-04-19 | Walcom Animal Science | Dairy cow feed and the use thereof |
WO2003045334A2 (en) * | 2001-11-29 | 2003-06-05 | Sound Pharmaceuticals Incorporated | Methods and compositions for ameliorating the undesirable effects of chemotherapy |
CN1635882B (zh) * | 2002-01-04 | 2010-11-10 | 桑得医药品公司 | 组合物在制备治疗听力丧失的药物中的用途 |
GB2386817B (en) * | 2002-02-20 | 2006-08-23 | Walcom Animal Science | Feed for fish and use therof |
US8017651B2 (en) * | 2002-11-22 | 2011-09-13 | Bionexus, Ltd. | Compositions and methods for the treatment of HIV-associated fat maldistribution and hyperlipidemia |
GB2398497A (en) * | 2003-02-19 | 2004-08-25 | Walcom Animal Science | Composition for improving immunity of animals |
US8029822B2 (en) * | 2003-05-22 | 2011-10-04 | Osmotica Kereskedelmi és Seolgáltató KFT | Rupturing controlled release device having a preformed passageway |
CN100391448C (zh) | 2003-11-19 | 2008-06-04 | 奥加生物药业(I.P.1)有限公司 | 提高乙醇代谢和减轻宿醉效应的物质和方法 |
AU2004308934B2 (en) * | 2003-12-19 | 2010-04-01 | Omega Bio-Pharma (I.P.3) Limited | Compositions and methods for treating diabetes |
US20050209441A1 (en) | 2004-03-22 | 2005-09-22 | Lile Jackson D | Process for promoting proper folding of human serum albumin using a human serum albumin ligand |
JP4976281B2 (ja) | 2004-05-03 | 2012-07-18 | オメガ バイオ‐ファーマ(アイ.ピー.3)リミテッド | 代謝を調節するための材料および方法 |
PT1879599E (pt) | 2005-04-20 | 2014-01-23 | Hutchinson Fred Cancer Res | Métodos, composições e artigos de fabrico para aumentar a capacidade de sobrevivência de células, tecidos, órgãos, e organismos |
AR057623A1 (es) | 2005-11-28 | 2007-12-05 | Omega Bio Pharma H K Ltd | Materiales y metodos para el tratamiento de las infecciones virales |
KR101394245B1 (ko) | 2005-12-30 | 2014-05-14 | 에스케이바이오팜 주식회사 | 아이속사졸 유도체 및 이의 용도 |
US20070172514A1 (en) | 2006-01-20 | 2007-07-26 | Francis Chi | Materials and methods for improving livestock productivity |
EA201600089A1 (ru) * | 2006-01-27 | 2017-01-30 | Те Риджентс Оф Те Юниверсити Оф Калифорния | Покрытые энтеросолюбильной оболочкой цистеамин и цистамин и их производные |
JP5583022B2 (ja) * | 2007-11-30 | 2014-09-03 | ザ レジェンツ オブ ザ ユニヴァースティ オブ カリフォルニア | システアミン生成物を用いる非アルコール性脂肪性肝炎(nash)の治療方法 |
WO2009100950A1 (en) | 2008-02-17 | 2009-08-20 | Walcom Animal Science (I.P.3) Limited | Materials and methods for improving the health of shrimp |
-
2007
- 2007-01-26 EA EA201600089A patent/EA201600089A1/ru unknown
- 2007-01-26 DK DK07762690.1T patent/DK1919458T6/en active
- 2007-01-26 CA CA2640531A patent/CA2640531C/en active Active
- 2007-01-26 AU AU2007210005A patent/AU2007210005C1/en active Active
- 2007-01-26 EP EP19206788.2A patent/EP3659588A1/en active Pending
- 2007-01-26 SI SI200731035T patent/SI1919458T1/sl unknown
- 2007-01-26 MX MX2008009647A patent/MX2008009647A/es active IP Right Grant
- 2007-01-26 HU HUE12169866A patent/HUE049307T2/hu unknown
- 2007-01-26 LT LTEP12169866.6T patent/LT2535044T/lt unknown
- 2007-01-26 EP EP12169866.6A patent/EP2535044B1/en not_active Revoked
- 2007-01-26 BR BRPI0707277-5A patent/BRPI0707277B1/pt active IP Right Grant
- 2007-01-26 US US11/990,869 patent/US8026284B2/en active Active
- 2007-01-26 SI SI200732147T patent/SI2535044T1/sl unknown
- 2007-01-26 DK DK12169866.6T patent/DK2535044T3/da active
- 2007-01-26 PT PT121698666T patent/PT2535044T/pt unknown
- 2007-01-26 ES ES07762690.1T patent/ES2388310T7/es active Active
- 2007-01-26 EP EP07762690.1A patent/EP1919458B3/en active Active
- 2007-01-26 PT PT07762690T patent/PT1919458E/pt unknown
- 2007-01-26 WO PCT/US2007/002325 patent/WO2007089670A2/en active Application Filing
- 2007-01-26 ES ES12169866T patent/ES2774755T3/es active Active
- 2007-01-26 EA EA200801752A patent/EA023971B1/ru not_active IP Right Cessation
- 2007-01-26 PL PL07762690T patent/PL1919458T6/pl unknown
- 2007-01-26 PL PL12169866T patent/PL2535044T3/pl unknown
-
2008
- 2008-07-24 IL IL193044A patent/IL193044A/en active IP Right Grant
-
2011
- 2011-07-25 US US13/190,396 patent/US8129433B2/en not_active Expired - Fee Related
-
2012
- 2012-02-17 US US13/399,900 patent/US20120237599A1/en not_active Abandoned
-
2014
- 2014-03-05 LU LU92389C patent/LU92389I2/xx unknown
- 2014-03-05 FR FR14C0018C patent/FR14C0018I1/fr active Active
- 2014-03-05 NL NL300649C patent/NL300649I2/nl unknown
- 2014-11-28 US US14/555,993 patent/US20150283100A1/en not_active Abandoned
-
2015
- 2015-06-26 US US14/752,499 patent/US9192590B2/en active Active
- 2015-06-26 US US14/752,383 patent/US9198882B2/en active Active
- 2015-11-24 US US14/950,234 patent/US9511039B2/en active Active
-
2016
- 2016-07-27 US US15/220,693 patent/US9750708B2/en active Active
- 2016-07-29 US US15/224,414 patent/US9795578B2/en active Active
- 2016-10-27 US US15/336,405 patent/US9814689B2/en active Active
-
2017
- 2017-07-21 US US15/656,884 patent/US9925157B2/en active Active
- 2017-07-21 US US15/656,863 patent/US9925156B2/en active Active
- 2017-07-21 US US15/656,903 patent/US9925158B2/en active Active
-
2018
- 2018-03-15 US US15/922,520 patent/US10485774B2/en active Active
-
2019
- 2019-11-14 US US16/684,000 patent/US11311507B2/en active Active
-
2020
- 2020-03-16 CY CY20201100240T patent/CY1122943T1/el unknown
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
IL193044A0 (en) | Enterically coated cysteamine, cystamine and derivatives thereof | |
PL2084148T3 (pl) | Fungicydowe pochodne N-cykloalkilo-karboksyamidowe, tiokarboksyamidowe i N-podstawione-karboksyimidoaminowe | |
SI2057153T1 (sl) | (3-ril-piperazin-1-il) derivati 6,7-dialkoksikuinazolin, 6,7-dialkoksiftalazin in 6,7-dialkoksiizokuinolin | |
EP2056742A4 (en) | MODELS, MATERIALS AND METHODS OF MANUFACTURING ENDOPROSTHETICS | |
IL196571A0 (en) | N-(aminoheteroaryl)-1h-indole-2-carboxamide derivatives, and preparation and therapeutic application thereof | |
IL192845A0 (en) | Benzamide and heteroarene derivatives | |
EP2039817A4 (en) | ABSORBENT, MULTILAYER ABSORBENT AND ABSORBENT ARTICLE | |
IL202376A (en) | History of pyridazinone, drugs and their kit containing and use | |
IL202378A (en) | Oxopyrazine history and herbicides containing them | |
EP2091527A4 (en) | SULFIDE, SULFOXIDE AND SULFON CHALCON ANALOGUE, DERIVATIVES THEREOF AND THERAPEUTIC APPLICATIONS THEREOF | |
ZA201000185B (en) | 17beta-cyano-18a-homo-19-nor-androst-4-ene derivative,use thereof and medicaments containing said derivative | |
IL187392A0 (en) | Thiazole derivatives, their preparation and use | |
IL192427A0 (en) | Derivatives of sulindac, use thereof and preparation thereof | |
IL198236A0 (en) | Diaryl, dipyridinyl and aryl-pyridinyl derivatives and uses thereof | |
EP2001833A4 (en) | ANTIDIABETIC CATARACT COMPOUNDS AND THEIR APPLICATION | |
EP2025667A4 (en) | 9, 10-SECOPREGNANDERIVAT AND MEDICINAL PRODUCTS | |
ZA201000187B (en) | 17b-cyano-19-nor-androst-4-ene derivative,use thereof and medicaments containing said derivative | |
ZA201000186B (en) | 17b-cyano-19-androst-4-ene derivative,use thereof and medicaments containing said derivative | |
ZA200900960B (en) | Arylpiperazine derivatives and uses thereof | |
IL194737A0 (en) | 2-alkenyl-3-aminothiophene derivatives and processes for the preparation thereof | |
GB0701295D0 (en) | Z-stilbenes derivatives and the pharmaceutical composition thereof | |
IL196621A0 (en) | Stent designs, materials and processing methods | |
GB0607060D0 (en) | Coated stent | |
IL196823A0 (en) | Tetraarylporphine derivatives and uses thereof | |
GB0614790D0 (en) | Active popping knickers |