SI1689724T1 - Spojine kinazolinona kot sredstva proti raku - Google Patents

Spojine kinazolinona kot sredstva proti raku

Info

Publication number
SI1689724T1
SI1689724T1 SI200431833T SI200431833T SI1689724T1 SI 1689724 T1 SI1689724 T1 SI 1689724T1 SI 200431833 T SI200431833 T SI 200431833T SI 200431833 T SI200431833 T SI 200431833T SI 1689724 T1 SI1689724 T1 SI 1689724T1
Authority
SI
Slovenia
Prior art keywords
quinazolinone compounds
anticancer agents
quinazolinone
alone
compounds
Prior art date
Application number
SI200431833T
Other languages
English (en)
Slovenian (sl)
Inventor
Weibo Wang
Liana M Lagniton
Ryan N Constantine
Manoj C Desai
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of SI1689724T1 publication Critical patent/SI1689724T1/sl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
    • C07D239/88—Oxygen atoms
    • C07D239/90—Oxygen atoms with acyclic radicals attached in position 2 or 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
SI200431833T 2003-11-25 2004-11-24 Spojine kinazolinona kot sredstva proti raku SI1689724T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US52505903P 2003-11-25 2003-11-25
EP04812051A EP1689724B1 (en) 2003-11-25 2004-11-24 Quinazolinone compounds as anticancer agents
PCT/US2004/039448 WO2005051922A1 (en) 2003-11-25 2004-11-24 Quinazolinone compounds as anticancer agents

Publications (1)

Publication Number Publication Date
SI1689724T1 true SI1689724T1 (sl) 2012-04-30

Family

ID=34632957

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200431833T SI1689724T1 (sl) 2003-11-25 2004-11-24 Spojine kinazolinona kot sredstva proti raku

Country Status (17)

Country Link
US (2) US7939539B2 (enExample)
EP (1) EP1689724B1 (enExample)
JP (2) JP4778439B2 (enExample)
KR (1) KR20060127413A (enExample)
CN (1) CN1886384A (enExample)
AT (1) ATE538103T1 (enExample)
AU (1) AU2004293464A1 (enExample)
CA (1) CA2546932A1 (enExample)
CY (1) CY1112478T1 (enExample)
DK (1) DK1689724T3 (enExample)
ES (1) ES2376552T3 (enExample)
IL (1) IL175714A0 (enExample)
PL (1) PL1689724T3 (enExample)
PT (1) PT1689724E (enExample)
SG (1) SG148202A1 (enExample)
SI (1) SI1689724T1 (enExample)
WO (1) WO2005051922A1 (enExample)

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CN101967127B (zh) * 2010-09-28 2013-05-29 中山大学 一种喹唑啉衍生物及其制备方法和制备抗癌药物中的应用
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US9365576B2 (en) 2012-05-24 2016-06-14 Novartis Ag Pyrrolopyrrolidinone compounds
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US9556180B2 (en) 2013-01-22 2017-01-31 Novartis Ag Pyrazolo[3,4-d]pyrimidinone compounds as inhibitors of the P53/MDM2 interaction
US9403827B2 (en) 2013-01-22 2016-08-02 Novartis Ag Substituted purinone compounds
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TW201815787A (zh) 2016-09-23 2018-05-01 美商基利科學股份有限公司 磷脂醯肌醇3-激酶抑制劑
TW201825465A (zh) 2016-09-23 2018-07-16 美商基利科學股份有限公司 磷脂醯肌醇3-激酶抑制劑
KR102583006B1 (ko) 2016-12-21 2023-09-27 바이엘 파마 악티엔게젤샤프트 효소적으로 절단가능한 기를 갖는 항체 약물 접합체 (adc)
CN110072556B (zh) 2016-12-21 2023-05-02 拜耳制药股份公司 具有ksp抑制剂的特异性抗体药物缀合物(adc)
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Also Published As

Publication number Publication date
PL1689724T3 (pl) 2012-05-31
IL175714A0 (en) 2006-09-05
DK1689724T3 (da) 2012-02-27
EP1689724B1 (en) 2011-12-21
ATE538103T1 (de) 2012-01-15
SG148202A1 (en) 2008-12-31
US20050209254A1 (en) 2005-09-22
CY1112478T1 (el) 2015-12-09
JP4778439B2 (ja) 2011-09-21
CA2546932A1 (en) 2005-06-09
PT1689724E (pt) 2012-02-06
US20110190293A1 (en) 2011-08-04
US7939539B2 (en) 2011-05-10
EP1689724A1 (en) 2006-08-16
AU2004293464A1 (en) 2005-06-09
KR20060127413A (ko) 2006-12-12
JP2011084570A (ja) 2011-04-28
WO2005051922A1 (en) 2005-06-09
ES2376552T3 (es) 2012-03-14
JP2007512368A (ja) 2007-05-17
CN1886384A (zh) 2006-12-27

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