SI1611115T1 - Spojini benzotiazolnih derivatov, sestavki in uporaba - Google Patents

Spojini benzotiazolnih derivatov, sestavki in uporaba

Info

Publication number
SI1611115T1
SI1611115T1 SI200431952T SI200431952T SI1611115T1 SI 1611115 T1 SI1611115 T1 SI 1611115T1 SI 200431952 T SI200431952 T SI 200431952T SI 200431952 T SI200431952 T SI 200431952T SI 1611115 T1 SI1611115 T1 SI 1611115T1
Authority
SI
Slovenia
Prior art keywords
compositions
derivative compounds
benzothiazole derivative
benzothiazole
compounds
Prior art date
Application number
SI200431952T
Other languages
English (en)
Slovenian (sl)
Inventor
William E. Klunk
Jr. Chester A. Mathis
Yanming Dr. Wang
Original Assignee
University Of Pittsburgh - Of The Commonwealth System Of Higher Education
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/388,173 external-priority patent/US7270800B2/en
Priority claimed from US10/645,847 external-priority patent/US20050043523A1/en
Application filed by University Of Pittsburgh - Of The Commonwealth System Of Higher Education filed Critical University Of Pittsburgh - Of The Commonwealth System Of Higher Education
Priority claimed from PCT/US2004/007797 external-priority patent/WO2004083195A1/en
Publication of SI1611115T1 publication Critical patent/SI1611115T1/sl

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62—Benzothiazoles
    • C07D277/64—Benzothiazoles with only hydrocarbon or substituted hydrocarbon radicals attached in position 2
    • C07D277/66—Benzothiazoles with only hydrocarbon or substituted hydrocarbon radicals attached in position 2 with aromatic rings or ring systems directly attached in position 2
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/60—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances involving radioactive labelled substances

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Neurosurgery (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Neurology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
SI200431952T 2003-03-14 2004-03-15 Spojini benzotiazolnih derivatov, sestavki in uporaba SI1611115T1 (sl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US10/388,173 US7270800B2 (en) 2000-08-24 2003-03-14 Thioflavin derivatives for use in antemortem diagnosis of Alzheimer's disease and in vivo imaging and prevention of amyloid deposition
US10/645,847 US20050043523A1 (en) 2003-08-22 2003-08-22 Benzothiazole derivative compounds, compositions and uses
EP04720788A EP1611115B1 (en) 2003-03-14 2004-03-15 Benzothiazole derivative compounds, compositions and uses
PCT/US2004/007797 WO2004083195A1 (en) 2003-03-14 2004-03-15 Benzothiazole derivative compounds, compositions and uses

Publications (1)

Publication Number Publication Date
SI1611115T1 true SI1611115T1 (sl) 2012-12-31

Family

ID=35057877

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200431952T SI1611115T1 (sl) 2003-03-14 2004-03-15 Spojini benzotiazolnih derivatov, sestavki in uporaba

Country Status (16)

Country Link
EP (1) EP1611115B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JP4875487B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CN (2) CN1784392A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU (2) AU2004221897B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
BE (1) BE2015C005I2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
BR (1) BRPI0408274B8 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CY (2) CY1113334T1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DK (1) DK1611115T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ES (1) ES2393921T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FR (1) FR15C0005I2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
HU (1) HUS1500006I1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NO (3) NO330861B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PL (1) PL1611115T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PT (1) PT1611115E (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
RU (1) RU2440995C2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
SI (1) SI1611115T1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2324686C2 (ru) * 2000-08-24 2008-05-20 Юнивесити Оф Питсбэг ПРОИЗВОДНЫЕ ТИОФЛАВИНА, СВЯЗЫВАЮЩИЕ АМИЛОИД, СПОСОБ ОБНАРУЖЕНИЯ in vivo ОТЛОЖЕНИЙ АМИЛОИДА И СПОСОБ РАСПОЗНАВАНИЯ БОЛЕЗНИ АЛЬЦГЕЙМЕРА
US7270800B2 (en) 2000-08-24 2007-09-18 University Of Pittsburgh Thioflavin derivatives for use in antemortem diagnosis of Alzheimer's disease and in vivo imaging and prevention of amyloid deposition
EP1755585A4 (en) * 2004-05-20 2009-04-01 Scripps Research Inst Transthyretin STABILIZATION
GB0516564D0 (en) * 2005-08-12 2005-09-21 Ge Healthcare Ltd Fluorination process
MX2009007880A (es) * 2007-01-30 2009-08-18 Ge Healthcare Ltd Herramientas para ayudar en el diagnostico de enfermedades neurodegenerativas.
CN101293878B (zh) * 2007-04-25 2010-12-15 中国科学院上海应用物理研究所 苯并噻唑苯胺类化合物及其制备方法和应用
EP2323697A2 (en) * 2008-07-24 2011-05-25 Siemens Medical Solutions USA, Inc. Imaging agents useful for identifying ad pathology
KR101631727B1 (ko) * 2008-09-23 2016-06-17 위스타 레보레이토리스 리미티드 응집된 타우 분자에 대한 리간드
RU2671506C2 (ru) 2013-09-26 2018-11-01 Ф. Хоффманн-Ля Рош Аг Имидазо[1,2-а]пиридин-7-амины в качестве средств визуализации
JP6260967B2 (ja) * 2013-11-06 2018-01-17 国立大学法人京都大学 放射性ヨウ素標識化合物、及び、これを含む放射性医薬
CN103613589B (zh) * 2013-11-29 2016-03-30 江苏华益科技有限公司 一种用于神经退行性疾病领域的新型pet显像剂前体及标准品的合成方法
BR112017004134A2 (pt) * 2014-08-29 2017-12-12 Chdi Foundation Inc ?sondas para imageamento de proteína de huntingtina?
CN109400615B (zh) * 2017-08-18 2021-07-16 上海交通大学医学院附属新华医院 一种靶向β-淀粉样蛋白的香豆素类化合物及其制备与应用
GR1009516B (el) * 2018-03-22 2019-05-02 Εκεφε Δημοκριτος Τρικαρβονυλο-συμπλοκα μεταλλων μεταπτωσεως με βενζο-ετεροκυκλικο παραγωγο του κυκλοπενταδιενυλικου ανιοντος με υψηλη διαπερατοτητα του αιματοεγκεφαλικου φραγμου για εφαρμογες στη διαγνωση και θεραπεια νοσων του κνς

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1237978A (zh) * 1996-11-22 1999-12-08 伊兰药品公司 N－(芳基/杂芳基)氨基酸衍生物、包括这些衍生物的药用组合物以及用这些化合物抑制β－淀粉样肽释放和或其合成的方法
GB9919673D0 (en) * 1999-08-20 1999-10-20 Cancer Res Campaign Tech 2-Arlybenzazole compounds
RU2324686C2 (ru) * 2000-08-24 2008-05-20 Юнивесити Оф Питсбэг ПРОИЗВОДНЫЕ ТИОФЛАВИНА, СВЯЗЫВАЮЩИЕ АМИЛОИД, СПОСОБ ОБНАРУЖЕНИЯ in vivo ОТЛОЖЕНИЙ АМИЛОИДА И СПОСОБ РАСПОЗНАВАНИЯ БОЛЕЗНИ АЛЬЦГЕЙМЕРА
JP2004524289A (ja) * 2000-12-22 2004-08-12 アストラゼネカ・アクチエボラーグ 治療化合物
AU2002258915B2 (en) * 2001-04-23 2007-11-15 The Trustees Of The University Of Pennsylvania Amyloid plaque aggregation inhibitors and diagnostic imaging agents
GB0229686D0 (en) * 2002-12-20 2003-01-29 Amersham Plc Solid-phase fluorination of benzothiazoles

Also Published As

Publication number Publication date
BRPI0408274B1 (pt) 2019-02-26
RU2440995C2 (ru) 2012-01-27
CN1784392A (zh) 2006-06-07
JP4875487B2 (ja) 2012-02-15
AU2011200667A1 (en) 2011-03-10
BRPI0408274A (pt) 2006-03-21
HK1086270A1 (en) 2006-09-15
AU2011200667B2 (en) 2011-12-22
HUS1500006I1 (hu) 2015-02-18
NO2015005I1 (no) 2015-03-02
EP1611115B1 (en) 2012-08-22
AU2004221897B2 (en) 2010-11-18
CN102532055A (zh) 2012-07-04
BRPI0408274B8 (pt) 2021-05-25
NO2015005I2 (no) 2015-02-18
JP2006522104A (ja) 2006-09-28
AU2004221897A2 (en) 2004-09-30
AU2004221897A9 (en) 2009-08-20
EP1611115A1 (en) 2006-01-04
NO330861B1 (no) 2011-08-01
ES2393921T3 (es) 2013-01-02
AU2004221897A1 (en) 2004-09-30
NO20054674L (no) 2005-12-13
CN102532055B (zh) 2016-05-11
NO20110980L (no) 2005-12-13
PT1611115E (pt) 2012-12-07
CY1113334T1 (el) 2015-12-09
PL1611115T3 (pl) 2013-01-31
CY2015007I1 (el) 2015-12-09
NO20054674D0 (no) 2005-10-11
DK1611115T3 (da) 2012-11-26
BE2015C005I2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 2023-03-07
RU2005131872A (ru) 2006-02-27
FR15C0005I2 (fr) 2015-07-24

Similar Documents

Publication Publication Date Title
EP1646382A4 (en) COMPOUNDS, COMPOSITIONS AND METHODS
EP1692112A4 (en) COMPOUNDS, COMPOSITIONS, AND METHODS
ZA200606027B (en) Thiazole derivative
AU2003262747A8 (en) Compounds, compositions, and methods
EP1503993A4 (en) COMPOUNDS, METHODS AND COMPOSITIONS
AU2003236527A8 (en) Compounds, compositions, and methods
AU2003265242A8 (en) Compounds, compositions, and methods
IL175300A0 (en) Indirubin-type compounds, compositions, and methods for their use
AU2003270015A8 (en) Compounds, compositions, and methods
AU2003299612A8 (en) Compounds, compositions and methods
IL164581A0 (en) Compounds, compositions and methods
EP1594849A4 (en) COMPOUNDS, COMPOSITIONS, AND METHODS
AU2003277079A8 (en) Compounds, compositions, and methods
PL374833A1 (en) 5-aryltetrazole compounds, compositions thereof, and uses therefor
SI1611115T1 (sl) Spojini benzotiazolnih derivatov, sestavki in uporaba
AU2003290507A8 (en) Compounds, compositions and methods
IL167936A0 (en) Compounds, compositions,and methods
EP1675834A4 (en) COMPOUNDS, COMPOSITIONS AND METHODS
EP1680420A4 (en) COMPOUNDS, COMPOSITIONS AND METHODS
GB0307695D0 (en) Compounds,compositions and processes
EP1613352A4 (en) MICRO-AGREED COMPOSITIONS
EP1620092A4 (en) COMPOUNDS, COMPOSITIONS AND METHODS
AU2003300031A8 (en) Compounds, compositions, and methods
AU2003267169A8 (en) Compounds, compositions and methods
EP1706111A4 (en) COMPOUNDS, COMPOSITIONS AND METHODS