NO2015005I1 - Flutemetamol (18F) - Google Patents

Flutemetamol (18F)

Info

Publication number
NO2015005I1
NO2015005I1 NO2015005C NO2015005C NO2015005I1 NO 2015005 I1 NO2015005 I1 NO 2015005I1 NO 2015005 C NO2015005 C NO 2015005C NO 2015005 C NO2015005 C NO 2015005C NO 2015005 I1 NO2015005 I1 NO 2015005I1
Authority
NO
Norway
Prior art keywords
fluoromethamol
Prior art date
Application number
NO2015005C
Other languages
English (en)
Other versions
NO2015005I2 (no
Original Assignee
Univ Pittsburgh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/388,173 external-priority patent/US7270800B2/en
Priority claimed from US10/645,847 external-priority patent/US20050043523A1/en
Priority claimed from PCT/US2004/007797 external-priority patent/WO2004083195A1/en
Application filed by Univ Pittsburgh filed Critical Univ Pittsburgh
Publication of NO2015005I2 publication Critical patent/NO2015005I2/no
Publication of NO2015005I1 publication Critical patent/NO2015005I1/no

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G01N33/6896Neurological disorders, e.g. Alzheimer's disease
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62Benzothiazoles
    • C07D277/64Benzothiazoles with only hydrocarbon or substituted hydrocarbon radicals attached in position 2
    • C07D277/66Benzothiazoles with only hydrocarbon or substituted hydrocarbon radicals attached in position 2 with aromatic rings or ring systems directly attached in position 2
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/60Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances involving radioactive labelled substances

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
NO2015005C 2003-03-14 2015-02-18 Flutemetamol (18F) NO2015005I1 (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10/388,173 US7270800B2 (en) 2000-08-24 2003-03-14 Thioflavin derivatives for use in antemortem diagnosis of Alzheimer's disease and in vivo imaging and prevention of amyloid deposition
US10/645,847 US20050043523A1 (en) 2003-08-22 2003-08-22 Benzothiazole derivative compounds, compositions and uses
PCT/US2004/007797 WO2004083195A1 (en) 2003-03-14 2004-03-15 Benzothiazole derivative compounds, compositions and uses

Publications (2)

Publication Number Publication Date
NO2015005I2 NO2015005I2 (no) 2015-02-18
NO2015005I1 true NO2015005I1 (no) 2015-03-02

Family

ID=35057877

Family Applications (3)

Application Number Title Priority Date Filing Date
NO20054674A NO330861B1 (no) 2003-03-14 2005-10-11 Benzotiazolavledede forbindelser, preparater og anvendelser
NO20110980A NO20110980L (no) 2003-03-14 2011-07-06 Benzotiazolavledede forbindelser, preparater og anvendelser
NO2015005C NO2015005I1 (no) 2003-03-14 2015-02-18 Flutemetamol (18F)

Family Applications Before (2)

Application Number Title Priority Date Filing Date
NO20054674A NO330861B1 (no) 2003-03-14 2005-10-11 Benzotiazolavledede forbindelser, preparater og anvendelser
NO20110980A NO20110980L (no) 2003-03-14 2011-07-06 Benzotiazolavledede forbindelser, preparater og anvendelser

Country Status (16)

Country Link
EP (1) EP1611115B1 (no)
JP (1) JP4875487B2 (no)
CN (2) CN1784392A (no)
AU (2) AU2004221897B2 (no)
BE (1) BE2015C005I2 (no)
BR (1) BRPI0408274B8 (no)
CY (2) CY1113334T1 (no)
DK (1) DK1611115T3 (no)
ES (1) ES2393921T3 (no)
HK (1) HK1086270A1 (no)
HU (1) HUS1500006I1 (no)
NO (3) NO330861B1 (no)
PL (1) PL1611115T3 (no)
PT (1) PT1611115E (no)
RU (1) RU2440995C2 (no)
SI (1) SI1611115T1 (no)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7270800B2 (en) 2000-08-24 2007-09-18 University Of Pittsburgh Thioflavin derivatives for use in antemortem diagnosis of Alzheimer's disease and in vivo imaging and prevention of amyloid deposition
PT2264018E (pt) 2000-08-24 2015-06-03 Univ Pittsburgh Derivados de tioflavina para uso no diagnóstico da doença de alzheimer
JP2007538103A (ja) * 2004-05-20 2007-12-27 ザ スクリップス リサーチ インスティテュート トランスサイレチン安定化
GB0516564D0 (en) * 2005-08-12 2005-09-21 Ge Healthcare Ltd Fluorination process
US20100080432A1 (en) * 2007-01-30 2010-04-01 Johan Axel Lilja Tools for aiding in the diagnosis of neurodegenerative diseases
CN101293878B (zh) * 2007-04-25 2010-12-15 中国科学院上海应用物理研究所 苯并噻唑苯胺类化合物及其制备方法和应用
CA2731738A1 (en) * 2008-07-24 2010-01-28 Siemens Medical Solutions Usa, Inc. Imaging agents useful for identifying ad pathology
DK2338059T3 (en) * 2008-09-23 2015-06-15 Wista Lab Ltd Ligands for aggregated tau molecules
WO2015044095A1 (en) * 2013-09-26 2015-04-02 F. Hoffmann-La Roche Ag Imidazo[1,2-a]pyridin-7-amines as imaging tools
JP6260967B2 (ja) * 2013-11-06 2018-01-17 国立大学法人京都大学 放射性ヨウ素標識化合物、及び、これを含む放射性医薬
CN103613589B (zh) * 2013-11-29 2016-03-30 江苏华益科技有限公司 一种用于神经退行性疾病领域的新型pet显像剂前体及标准品的合成方法
ES2818107T3 (es) * 2014-08-29 2021-04-09 Chdi Foundation Inc Sondas para obtener imágenes de la proteína huntingtina
CN109400615B (zh) * 2017-08-18 2021-07-16 上海交通大学医学院附属新华医院 一种靶向β-淀粉样蛋白的香豆素类化合物及其制备与应用
GR1009516B (el) * 2018-03-22 2019-05-02 Εκεφε Δημοκριτος Τρικαρβονυλο-συμπλοκα μεταλλων μεταπτωσεως με βενζο-ετεροκυκλικο παραγωγο του κυκλοπενταδιενυλικου ανιοντος με υψηλη διαπερατοτητα του αιματοεγκεφαλικου φραγμου για εφαρμογες στη διαγνωση και θεραπεια νοσων του κνς

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR9714358A (pt) * 1996-11-22 2000-03-21 Elan Pharm Inc Derivados de n- (arila/heteroarila) amino ácido,composições farmacêuticas compreendendo os mesmos, e métodos para a inibição de liberação de peptìdeo beta-amilóide e/ou sua sìntese por uso de tais compostos
GB9919673D0 (en) * 1999-08-20 1999-10-20 Cancer Res Campaign Tech 2-Arlybenzazole compounds
PT2264018E (pt) * 2000-08-24 2015-06-03 Univ Pittsburgh Derivados de tioflavina para uso no diagnóstico da doença de alzheimer
EP1345914A1 (en) * 2000-12-22 2003-09-24 AstraZeneca AB Therapeutic compounds
WO2002085903A2 (en) * 2001-04-23 2002-10-31 The Trustees Of The University Of Pennsylvania Amyloid plaque aggregation inhibitors and diagnostic imaging agents
GB0229686D0 (en) * 2002-12-20 2003-01-29 Amersham Plc Solid-phase fluorination of benzothiazoles

Also Published As

Publication number Publication date
JP2006522104A (ja) 2006-09-28
BRPI0408274A (pt) 2006-03-21
CY1113334T1 (el) 2015-12-09
AU2004221897A9 (en) 2009-08-20
CN1784392A (zh) 2006-06-07
NO20054674D0 (no) 2005-10-11
SI1611115T1 (sl) 2012-12-31
BRPI0408274B1 (pt) 2019-02-26
NO20054674L (no) 2005-12-13
ES2393921T3 (es) 2013-01-02
PT1611115E (pt) 2012-12-07
CN102532055B (zh) 2016-05-11
RU2440995C2 (ru) 2012-01-27
AU2011200667B2 (en) 2011-12-22
NO330861B1 (no) 2011-08-01
BRPI0408274B8 (pt) 2021-05-25
EP1611115B1 (en) 2012-08-22
CY2015007I1 (el) 2015-12-09
AU2004221897A2 (en) 2004-09-30
CN102532055A (zh) 2012-07-04
JP4875487B2 (ja) 2012-02-15
NO20110980L (no) 2005-12-13
BE2015C005I2 (no) 2023-03-07
PL1611115T3 (pl) 2013-01-31
NO2015005I2 (no) 2015-02-18
DK1611115T3 (da) 2012-11-26
AU2004221897A1 (en) 2004-09-30
AU2011200667A1 (en) 2011-03-10
HUS1500006I1 (hu) 2015-02-18
AU2004221897B2 (en) 2010-11-18
RU2005131872A (ru) 2006-02-27
EP1611115A1 (en) 2006-01-04
HK1086270A1 (en) 2006-09-15

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