SI1067941T1 - Antitumor composition containing a synergistic combination of an anthracycline derivative with a camptothecin derivate - Google Patents

Antitumor composition containing a synergistic combination of an anthracycline derivative with a camptothecin derivate

Info

Publication number
SI1067941T1
SI1067941T1 SI9930675T SI9930675T SI1067941T1 SI 1067941 T1 SI1067941 T1 SI 1067941T1 SI 9930675 T SI9930675 T SI 9930675T SI 9930675 T SI9930675 T SI 9930675T SI 1067941 T1 SI1067941 T1 SI 1067941T1
Authority
SI
Slovenia
Prior art keywords
composition containing
synergistic combination
anthracycline derivative
antitumor composition
camptothecin derivate
Prior art date
Application number
SI9930675T
Other languages
English (en)
Slovenian (sl)
Inventor
Cristina Geroni
Marina Ripamonti
Michele Caruso
Antonino Suarato
Original Assignee
Pharmacia Italia S.P.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia Italia S.P.A. filed Critical Pharmacia Italia S.P.A.
Publication of SI1067941T1 publication Critical patent/SI1067941T1/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/704Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
SI9930675T 1998-03-24 1999-03-19 Antitumor composition containing a synergistic combination of an anthracycline derivative with a camptothecin derivate SI1067941T1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9806324.1A GB9806324D0 (en) 1998-03-24 1998-03-24 Antitumour synergetic composition
PCT/EP1999/001897 WO1999048503A1 (en) 1998-03-24 1999-03-19 Antitumor composition containing a synergistic combination of an anthracycline derivative with a camptothecin derivate
EP99914528A EP1067941B1 (en) 1998-03-24 1999-03-19 Antitumor composition containing a synergistic combination of an anthracycline derivative with a camptothecin derivate

Publications (1)

Publication Number Publication Date
SI1067941T1 true SI1067941T1 (en) 2005-02-28

Family

ID=10829188

Family Applications (1)

Application Number Title Priority Date Filing Date
SI9930675T SI1067941T1 (en) 1998-03-24 1999-03-19 Antitumor composition containing a synergistic combination of an anthracycline derivative with a camptothecin derivate

Country Status (29)

Country Link
US (1) US6403563B1 (uk)
EP (1) EP1067941B1 (uk)
JP (1) JP2002507571A (uk)
KR (1) KR20010034619A (uk)
CN (2) CN1150002C (uk)
AR (1) AR018166A1 (uk)
AT (1) ATE271388T1 (uk)
AU (1) AU758191B2 (uk)
BR (1) BR9908391A (uk)
CA (1) CA2324610A1 (uk)
CZ (1) CZ295368B6 (uk)
DE (1) DE69918819T2 (uk)
DK (1) DK1067941T3 (uk)
EA (1) EA003134B1 (uk)
ES (1) ES2226366T3 (uk)
GB (1) GB9806324D0 (uk)
HU (1) HUP0101615A3 (uk)
ID (1) ID26091A (uk)
IL (1) IL138035A0 (uk)
MY (1) MY133016A (uk)
NO (1) NO20004703L (uk)
NZ (1) NZ507570A (uk)
PL (1) PL343098A1 (uk)
PT (1) PT1067941E (uk)
SI (1) SI1067941T1 (uk)
TW (1) TW576740B (uk)
UA (1) UA63000C2 (uk)
WO (1) WO1999048503A1 (uk)
ZA (1) ZA992255B (uk)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6820065B1 (en) * 1998-03-18 2004-11-16 Ascom Hasler Mailing Systems Inc. System and method for management of postage meter licenses
GB9904387D0 (en) * 1999-02-25 1999-04-21 Pharmacia & Upjohn Spa Antitumour synergistic composition
GB9909925D0 (en) * 1999-04-29 1999-06-30 Pharmacia & Upjohn Spa Combined preparations comprising anthracycline derivatives
GB9916882D0 (en) * 1999-07-19 1999-09-22 Pharmacia & Upjohn Spa Antitumor synergistic composition
GB9926843D0 (en) * 1999-11-12 2000-01-12 Pharmacia & Upjohn Spa Lipid complex of alkycyclines
US6627614B1 (en) * 2002-06-05 2003-09-30 Super Gen, Inc. Sequential therapy comprising a 20(S)-camptothecin and an anthracycline
EP1985286A1 (en) * 2007-04-24 2008-10-29 Biocompatibles UK Limited Microspheres for treatment of brain tumours
US8349764B2 (en) 2007-10-31 2013-01-08 Molycorp Minerals, Llc Composition for treating a fluid
US20090107925A1 (en) * 2007-10-31 2009-04-30 Chevron U.S.A. Inc. Apparatus and process for treating an aqueous solution containing biological contaminants
US20110207760A1 (en) * 2010-02-23 2011-08-25 Valery Alakhov Sn-38 compositions
WO2011160063A2 (en) 2010-06-18 2011-12-22 Myriad Genetics, Inc. Methods and materials for assessing loss of heterozygosity
DK2609216T3 (en) 2010-08-24 2016-09-12 Dana Farber Cancer Inst Inc Methods to predict anti-cancer response
US9233863B2 (en) 2011-04-13 2016-01-12 Molycorp Minerals, Llc Rare earth removal of hydrated and hydroxyl species
EP2721181B1 (en) 2011-06-17 2019-12-18 Myriad Genetics, Inc. Methods and materials for assessing allelic imbalance
AU2012358244A1 (en) 2011-12-21 2014-06-12 Myriad Genetics, Inc. Methods and materials for assessing loss of heterozygosity
NZ628813A (en) 2012-02-23 2015-10-30 Univ Denmark Tech Dtu Methods for predicting anti-cancer response
CA3190075A1 (en) 2012-06-07 2013-12-12 Institut Curie Methods for detecting inactivation of the homologous recombination pathway (brca1/2) in human tumors
US10308986B2 (en) 2013-03-14 2019-06-04 Children's Medical Center Corporation Cancer diagnosis, treatment selection and treatment
AU2014248007B2 (en) 2013-04-05 2020-03-26 Myriad Genetics, Inc. Methods and materials for assessing homologous recombination deficiency
US11149316B2 (en) 2013-12-09 2021-10-19 Institut Curie Methods for detecting inactivation of the homologous recombination pathway (BRCA1/2) in human tumors
MX370462B (es) 2014-03-07 2019-12-13 Secure Natural Resources Llc Oxido de cerio (iv) con propiedades de remocion de arsenico excepcionales.
DK3180447T3 (da) 2014-08-15 2020-06-15 Myriad Genetics Inc Fremgangsmåder og materialer til analyse af homolog rekombinationsdeficiens
EP4141127A1 (en) 2021-08-30 2023-03-01 Zentrum Familiärer Brust- und Eierstockkrebs Universitätsklinik Köln Method for assessing homologous recombination deficiency in ovarian cancer cells

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9114549D0 (en) * 1991-07-05 1991-08-21 Erba Carlo Spa Mono and bis alkylamino-anthracyclines
GB9325417D0 (en) * 1993-12-13 1994-02-16 Erba Carlo Spa 3'- aziridino-anthracycline derivatives

Also Published As

Publication number Publication date
ATE271388T1 (de) 2004-08-15
NZ507570A (en) 2003-01-31
MY133016A (en) 2007-10-31
IL138035A0 (en) 2001-10-31
EP1067941A1 (en) 2001-01-17
WO1999048503A1 (en) 1999-09-30
NO20004703D0 (no) 2000-09-20
HUP0101615A2 (hu) 2001-10-28
CZ20003493A3 (cs) 2001-02-14
DK1067941T3 (da) 2004-11-29
ZA992255B (en) 1999-10-05
NO20004703L (no) 2000-09-20
GB9806324D0 (en) 1998-05-20
PT1067941E (pt) 2004-12-31
US6403563B1 (en) 2002-06-11
AU3331499A (en) 1999-10-18
CZ295368B6 (cs) 2005-07-13
BR9908391A (pt) 2000-10-31
UA63000C2 (en) 2004-01-15
ID26091A (id) 2000-11-23
HUP0101615A3 (en) 2002-12-28
EA200000978A1 (ru) 2001-02-26
EA003134B1 (ru) 2003-02-27
TW576740B (en) 2004-02-21
JP2002507571A (ja) 2002-03-12
CN1294516A (zh) 2001-05-09
CA2324610A1 (en) 1999-09-30
ES2226366T3 (es) 2005-03-16
DE69918819T2 (de) 2005-08-18
EP1067941B1 (en) 2004-07-21
CN1150002C (zh) 2004-05-19
DE69918819D1 (de) 2004-08-26
KR20010034619A (ko) 2001-04-25
AR018166A1 (es) 2001-10-31
AU758191B2 (en) 2003-03-20
PL343098A1 (en) 2001-07-30
CN1528334A (zh) 2004-09-15

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