SI0922034T1 - Derivati tetrahidrokinolina kot eaa antagonisti - Google Patents
Derivati tetrahidrokinolina kot eaa antagonistiInfo
- Publication number
- SI0922034T1 SI0922034T1 SI9730404T SI9730404T SI0922034T1 SI 0922034 T1 SI0922034 T1 SI 0922034T1 SI 9730404 T SI9730404 T SI 9730404T SI 9730404 T SI9730404 T SI 9730404T SI 0922034 T1 SI0922034 T1 SI 0922034T1
- Authority
- SI
- Slovenia
- Prior art keywords
- tetrahydroquinoline derivatives
- eaa antagonists
- eaa
- antagonists
- tetrahydroquinoline
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9617305.9A GB9617305D0 (en) | 1996-08-17 | 1996-08-17 | Heterocyclic compounds |
| EP97943809A EP0922034B1 (en) | 1996-08-17 | 1997-08-14 | Tetrahydroquinoline derivatives as eaa antagonists |
| PCT/EP1997/004440 WO1998007704A1 (en) | 1996-08-17 | 1997-08-14 | Tetrahydroquinoline derivatives as eaa antagonists |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SI0922034T1 true SI0922034T1 (sl) | 2003-02-28 |
Family
ID=10798623
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SI9730404T SI0922034T1 (sl) | 1996-08-17 | 1997-08-14 | Derivati tetrahidrokinolina kot eaa antagonisti |
Country Status (34)
| Country | Link |
|---|---|
| US (1) | US6479488B1 (sl) |
| EP (1) | EP0922034B1 (sl) |
| JP (1) | JP4108129B2 (sl) |
| KR (1) | KR100552864B1 (sl) |
| CN (1) | CN1131214C (sl) |
| AP (1) | AP877A (sl) |
| AR (1) | AR008296A1 (sl) |
| AT (1) | ATE221052T1 (sl) |
| AU (1) | AU724473B2 (sl) |
| BR (1) | BR9711311B1 (sl) |
| CA (1) | CA2264118C (sl) |
| CO (1) | CO4900066A1 (sl) |
| CZ (1) | CZ296250B6 (sl) |
| DE (1) | DE69714265T2 (sl) |
| DK (1) | DK0922034T3 (sl) |
| EA (1) | EA001704B1 (sl) |
| ES (1) | ES2181030T3 (sl) |
| GB (1) | GB9617305D0 (sl) |
| HU (1) | HU225797B1 (sl) |
| ID (1) | ID18095A (sl) |
| IL (1) | IL128141A0 (sl) |
| IS (1) | IS4953A (sl) |
| MY (1) | MY116952A (sl) |
| NO (1) | NO312241B1 (sl) |
| NZ (1) | NZ333812A (sl) |
| PE (1) | PE107098A1 (sl) |
| PL (1) | PL194532B1 (sl) |
| PT (1) | PT922034E (sl) |
| SI (1) | SI0922034T1 (sl) |
| TR (1) | TR199900336T2 (sl) |
| TW (1) | TW449582B (sl) |
| WO (1) | WO1998007704A1 (sl) |
| YU (1) | YU6799A (sl) |
| ZA (1) | ZA977326B (sl) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9706294D0 (en) * | 1997-03-26 | 1997-05-14 | Glaxo Wellcome Spa | Heterocyclic compound |
| MY125037A (en) * | 1998-06-10 | 2006-07-31 | Glaxo Wellcome Spa | 1,2,3,4 tetrahydroquinoline derivatives |
| US6455734B1 (en) * | 2000-08-09 | 2002-09-24 | Magnesium Diagnostics, Inc. | Antagonists of the magnesium binding defect as therapeutic agents and methods for treatment of abnormal physiological states |
| GB9929037D0 (en) | 1999-12-08 | 2000-02-02 | Glaxo Wellcome Spa | Heterocyclic derivatives |
| DE10132725A1 (de) | 2001-07-05 | 2006-08-03 | Grünenthal GmbH | Substituierte γ-Lactonverbindungen |
| ES2251624T3 (es) * | 2001-12-28 | 2006-05-01 | Acadia Pharmaceuticals Inc. | Analogos de la tetrahidroquinolina como los agonistas muscarinicos. |
| US20050085463A1 (en) * | 2003-01-23 | 2005-04-21 | Weiner David M. | Use of N-desmethylclozapine to treat human neuropsychiatric disease |
| EP1589974A2 (en) * | 2003-01-23 | 2005-11-02 | Acadia Pharmaceuticals Inc. | Use of n-desmethylclozapine to treat human neuropsychiatric disease |
| US20050250767A1 (en) * | 2003-01-23 | 2005-11-10 | Weiner David M | Use of N-desmethylclozapine to treat human neuropsychiatric disease |
| WO2004073639A2 (en) * | 2003-02-19 | 2004-09-02 | Merck & Co. Inc. | Treatment of psychosis with a muscarinic m1 receptor ectopic activator |
| CN101962369A (zh) * | 2003-12-22 | 2011-02-02 | 阿卡蒂亚药品公司 | 氨基取代的二芳基[a,d]环庚烯类似物作为毒蕈碱激动剂的用途及神经精神疾病的治疗方法 |
| EP1756070A2 (en) * | 2004-04-01 | 2007-02-28 | Acadia Pharmaceuticals Inc. | Crystalline forms of n-desmethylclozapine |
| RU2451014C2 (ru) * | 2005-07-22 | 2012-05-20 | Мотида Фармасьютикал Ко., Лтд. | Новое производное гетероциклиден ацетамида |
| PT1908753E (pt) | 2005-07-22 | 2015-02-06 | Mochida Pharm Co Ltd | Novo derivado acetamida de heterociclideno |
| US9427419B2 (en) | 2005-09-12 | 2016-08-30 | Abela Pharmaceuticals, Inc. | Compositions comprising dimethyl sulfoxide (DMSO) |
| WO2007033180A1 (en) | 2005-09-12 | 2007-03-22 | Abela Pharmaceuticals, Inc. | Materials for facilitating administration of dimethyl sulfoxide (dmso) and related compounds |
| US8480797B2 (en) | 2005-09-12 | 2013-07-09 | Abela Pharmaceuticals, Inc. | Activated carbon systems for facilitating use of dimethyl sulfoxide (DMSO) by removal of same, related compounds, or associated odors |
| AU2006291134C1 (en) | 2005-09-12 | 2013-08-15 | Abela Pharmaceuticals, Inc. | Systems for removing dimethyl sulfoxide (DMSO) or related compounds, or odors associated with same |
| US20070105836A1 (en) * | 2005-10-31 | 2007-05-10 | Lars Pettersson | Prodrugs of muscarinic agonists and methods of treatment of neuropsychiatric disorders |
| BRPI0921494A2 (pt) | 2008-11-03 | 2018-10-30 | Prad Reasearch And Development Ltd | método de planejamento de uma operação de amostragem para uma formação subterrãnea, método de contolar uma operação de amostragem de formação subterrânea, método de controlar uma operação de perfuração para uma formação subterrãnea, e método de realizar uma amostragem durante a operação de perfuração. |
| CA2779111C (en) | 2009-10-30 | 2019-08-13 | Abela Pharmaceuticals, Inc. | Dimethyl sulfoxide (dmso) and methylsulfonylmethane (msm) formulations to treat osteoarthritis |
| CA2850707C (en) | 2011-10-03 | 2023-03-21 | The University Of Utah Research Foundation | Application of 5-ht6 receptor antagonists for the alleviation of cognitive deficits of down syndrome |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL93610A0 (en) * | 1989-03-08 | 1990-12-23 | Merck Sharp & Dohme | Tetrahydroquinoline derivatives,their preparation and pharmaceutical compositions containing them |
| IL123322A0 (en) * | 1995-09-29 | 1998-09-24 | Glaxo Wellcome Spa | Tetrahydroquinolines their preparation and pharmaceutical compositions containing them |
-
1996
- 1996-08-17 GB GBGB9617305.9A patent/GB9617305D0/en active Pending
-
1997
- 1997-08-14 CA CA002264118A patent/CA2264118C/en not_active Expired - Fee Related
- 1997-08-14 PE PE1997000718A patent/PE107098A1/es not_active Application Discontinuation
- 1997-08-14 KR KR1019997001280A patent/KR100552864B1/ko not_active IP Right Cessation
- 1997-08-14 YU YU6799A patent/YU6799A/sh unknown
- 1997-08-14 BR BRPI9711311-5A patent/BR9711311B1/pt not_active IP Right Cessation
- 1997-08-14 AT AT97943809T patent/ATE221052T1/de not_active IP Right Cessation
- 1997-08-14 CN CN97197233A patent/CN1131214C/zh not_active Expired - Fee Related
- 1997-08-14 CO CO97046782A patent/CO4900066A1/es unknown
- 1997-08-14 TR TR1999/00336T patent/TR199900336T2/xx unknown
- 1997-08-14 WO PCT/EP1997/004440 patent/WO1998007704A1/en active IP Right Grant
- 1997-08-14 ZA ZA977326A patent/ZA977326B/xx unknown
- 1997-08-14 JP JP51037298A patent/JP4108129B2/ja not_active Expired - Fee Related
- 1997-08-14 EA EA199900121A patent/EA001704B1/ru not_active IP Right Cessation
- 1997-08-14 AR ARP970103703A patent/AR008296A1/es active IP Right Grant
- 1997-08-14 MY MYPI97003742A patent/MY116952A/en unknown
- 1997-08-14 CZ CZ0052999A patent/CZ296250B6/cs not_active IP Right Cessation
- 1997-08-14 NZ NZ333812A patent/NZ333812A/xx active Application Revival
- 1997-08-14 PT PT97943809T patent/PT922034E/pt unknown
- 1997-08-14 IL IL12814197A patent/IL128141A0/xx not_active IP Right Cessation
- 1997-08-14 PL PL97331562A patent/PL194532B1/pl not_active IP Right Cessation
- 1997-08-14 DE DE69714265T patent/DE69714265T2/de not_active Expired - Lifetime
- 1997-08-14 AU AU45518/97A patent/AU724473B2/en not_active Ceased
- 1997-08-14 AP APAP/P/1999/001459A patent/AP877A/en active
- 1997-08-14 US US09/147,568 patent/US6479488B1/en not_active Expired - Fee Related
- 1997-08-14 SI SI9730404T patent/SI0922034T1/sl unknown
- 1997-08-14 DK DK97943809T patent/DK0922034T3/da active
- 1997-08-14 HU HU9903108A patent/HU225797B1/hu not_active IP Right Cessation
- 1997-08-14 ID IDP972834A patent/ID18095A/id unknown
- 1997-08-14 ES ES97943809T patent/ES2181030T3/es not_active Expired - Lifetime
- 1997-08-14 EP EP97943809A patent/EP0922034B1/en not_active Expired - Lifetime
- 1997-08-30 TW TW086112442A patent/TW449582B/zh not_active IP Right Cessation
-
1999
- 1999-01-22 IS IS4953A patent/IS4953A/is unknown
- 1999-02-16 NO NO19990723A patent/NO312241B1/no not_active IP Right Cessation
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