SI0759780T1 - Improved modified live brsv vaccine - Google Patents
Improved modified live brsv vaccineInfo
- Publication number
- SI0759780T1 SI0759780T1 SI9530374T SI9530374T SI0759780T1 SI 0759780 T1 SI0759780 T1 SI 0759780T1 SI 9530374 T SI9530374 T SI 9530374T SI 9530374 T SI9530374 T SI 9530374T SI 0759780 T1 SI0759780 T1 SI 0759780T1
- Authority
- SI
- Slovenia
- Prior art keywords
- immunity
- adjuvant
- brsv
- modified live
- polyoxypropylene
- Prior art date
Links
- 229960005486 vaccine Drugs 0.000 title abstract 2
- 241000711895 Bovine orthopneumovirus Species 0.000 abstract 5
- 229920003171 Poly (ethylene oxide) Polymers 0.000 abstract 3
- 239000002671 adjuvant Substances 0.000 abstract 3
- PRAKJMSDJKAYCZ-UHFFFAOYSA-N dodecahydrosqualene Natural products CC(C)CCCC(C)CCCC(C)CCCCC(C)CCCC(C)CCCC(C)C PRAKJMSDJKAYCZ-UHFFFAOYSA-N 0.000 abstract 3
- 230000036039 immunity Effects 0.000 abstract 3
- 208000015181 infectious disease Diseases 0.000 abstract 2
- -1 polyoxypropylene Polymers 0.000 abstract 2
- 229920001451 polypropylene glycol Polymers 0.000 abstract 2
- YYGNTYWPHWGJRM-UHFFFAOYSA-N (6E,10E,14E,18E)-2,6,10,15,19,23-hexamethyltetracosa-2,6,10,14,18,22-hexaene Chemical compound CC(C)=CCCC(C)=CCCC(C)=CCCC=C(C)CCC=C(C)CCC=C(C)C YYGNTYWPHWGJRM-UHFFFAOYSA-N 0.000 abstract 1
- 239000004215 Carbon black (E152) Substances 0.000 abstract 1
- 230000024932 T cell mediated immunity Effects 0.000 abstract 1
- BHEOSNUKNHRBNM-UHFFFAOYSA-N Tetramethylsqualene Natural products CC(=C)C(C)CCC(=C)C(C)CCC(C)=CCCC=C(C)CCC(C)C(=C)CCC(C)C(C)=C BHEOSNUKNHRBNM-UHFFFAOYSA-N 0.000 abstract 1
- 229920001400 block copolymer Polymers 0.000 abstract 1
- 229920001577 copolymer Polymers 0.000 abstract 1
- 229930195733 hydrocarbon Natural products 0.000 abstract 1
- 150000002430 hydrocarbons Chemical class 0.000 abstract 1
- 230000028993 immune response Effects 0.000 abstract 1
- JXTPJDDICSTXJX-UHFFFAOYSA-N n-Triacontane Natural products CCCCCCCCCCCCCCCCCCCCCCCCCCCCCC JXTPJDDICSTXJX-UHFFFAOYSA-N 0.000 abstract 1
- 235000010482 polyoxyethylene sorbitan monooleate Nutrition 0.000 abstract 1
- 239000000244 polyoxyethylene sorbitan monooleate Substances 0.000 abstract 1
- 229920000053 polysorbate 80 Polymers 0.000 abstract 1
- 230000003248 secreting effect Effects 0.000 abstract 1
- 229940032094 squalane Drugs 0.000 abstract 1
- 229940031439 squalene Drugs 0.000 abstract 1
- TUHBEKDERLKLEC-UHFFFAOYSA-N squalene Natural products CC(=CCCC(=CCCC(=CCCC=C(/C)CCC=C(/C)CC=C(C)C)C)C)C TUHBEKDERLKLEC-UHFFFAOYSA-N 0.000 abstract 1
- 239000004094 surface-active agent Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/245—Herpetoviridae, e.g. herpes simplex virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/155—Paramyxoviridae, e.g. parainfluenza virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5254—Virus avirulent or attenuated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6093—Synthetic polymers, e.g. polyethyleneglycol [PEG], Polymers or copolymers of (D) glutamate and (D) lysine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/70—Multivalent vaccine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16711—Varicellovirus, e.g. human herpesvirus 3, Varicella Zoster, pseudorabies
- C12N2710/16734—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18511—Pneumovirus, e.g. human respiratory syncytial virus
- C12N2760/18534—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18611—Respirovirus, e.g. Bovine, human parainfluenza 1,3
- C12N2760/18634—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24311—Pestivirus, e.g. bovine viral diarrhea virus
- C12N2770/24334—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Virology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Pulmonology (AREA)
- Oncology (AREA)
- Molecular Biology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US24037394A | 1994-05-10 | 1994-05-10 | |
| PCT/US1995/006053 WO1995030437A1 (en) | 1994-05-10 | 1995-05-08 | Improved modified live brsv vaccine |
| EP95918442A EP0759780B1 (en) | 1994-05-10 | 1995-05-08 | Improved modified live brsv vaccine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SI0759780T1 true SI0759780T1 (en) | 2000-12-31 |
Family
ID=22906268
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SI9530731T SI0968722T1 (sl) | 1994-05-10 | 1995-05-08 | Izboljĺ ano, modificirano ĺ˝ivo cepivo proti brsv |
| SI9530374T SI0759780T1 (en) | 1994-05-10 | 1995-05-08 | Improved modified live brsv vaccine |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SI9530731T SI0968722T1 (sl) | 1994-05-10 | 1995-05-08 | Izboljĺ ano, modificirano ĺ˝ivo cepivo proti brsv |
Country Status (20)
| Country | Link |
|---|---|
| US (2) | US5733555A (zh) |
| EP (4) | EP0968722B1 (zh) |
| JP (3) | JP3993230B2 (zh) |
| KR (1) | KR100374434B1 (zh) |
| CN (1) | CN1268393C (zh) |
| AT (2) | ATE195255T1 (zh) |
| AU (1) | AU711350B2 (zh) |
| BR (1) | BR9507717A (zh) |
| CA (1) | CA2189979C (zh) |
| DE (2) | DE69535520T2 (zh) |
| DK (2) | DK0759780T3 (zh) |
| ES (3) | ES2429401T3 (zh) |
| GR (1) | GR3034402T3 (zh) |
| HK (1) | HK1024412A1 (zh) |
| MY (1) | MY111829A (zh) |
| NZ (1) | NZ285324A (zh) |
| PT (3) | PT1820512E (zh) |
| SI (2) | SI0968722T1 (zh) |
| WO (1) | WO1995030437A1 (zh) |
| ZA (1) | ZA953703B (zh) |
Families Citing this family (60)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6582728B1 (en) * | 1992-07-08 | 2003-06-24 | Inhale Therapeutic Systems, Inc. | Spray drying of macromolecules to produce inhaleable dry powders |
| US6673335B1 (en) * | 1992-07-08 | 2004-01-06 | Nektar Therapeutics | Compositions and methods for the pulmonary delivery of aerosolized medicaments |
| CZ286632B6 (cs) * | 1992-09-29 | 2000-05-17 | Inhale Therapeutic Systems | Farmaceutický prostředek |
| CA2136677A1 (en) * | 1993-12-29 | 1995-06-30 | Intervet, Inc. | Method of intranasally administering to bovines a trivalent vaccine containing modified live ibrv, pl3v and brsv |
| ES2316917T3 (es) * | 1994-03-07 | 2009-04-16 | Nektar Therapeutics | Metodos y composiciones para suministro pulmonar de insulina. |
| US20030113273A1 (en) * | 1996-06-17 | 2003-06-19 | Patton John S. | Methods and compositions for pulmonary delivery of insulin |
| PT1820512E (pt) * | 1994-05-10 | 2013-10-09 | Boehringer Ingelheim Vetmed | Vacina viva modificada melhorada contra brsv |
| NZ285664A (en) * | 1994-05-18 | 1998-07-28 | Inhale Therapeutic Syst | Dry powder interferon composition adapted for pulmonary delivery |
| US6290991B1 (en) * | 1994-12-02 | 2001-09-18 | Quandrant Holdings Cambridge Limited | Solid dose delivery vehicle and methods of making same |
| JP3939752B2 (ja) * | 1994-10-05 | 2007-07-04 | バンダービルト ユニバーシティー | パラミクソウイルスワクチン用アジュバントとしてのインターロイキン−１２ |
| US6359054B1 (en) * | 1994-11-18 | 2002-03-19 | Supratek Pharma Inc. | Polynucleotide compositions for intramuscular administration |
| US20030035778A1 (en) * | 1997-07-14 | 2003-02-20 | Robert Platz | Methods and compositions for the dry powder formulation of interferon |
| US6565885B1 (en) * | 1997-09-29 | 2003-05-20 | Inhale Therapeutic Systems, Inc. | Methods of spray drying pharmaceutical compositions |
| US6309623B1 (en) * | 1997-09-29 | 2001-10-30 | Inhale Therapeutic Systems, Inc. | Stabilized preparations for use in metered dose inhalers |
| US20060165606A1 (en) * | 1997-09-29 | 2006-07-27 | Nektar Therapeutics | Pulmonary delivery particles comprising water insoluble or crystalline active agents |
| US6908618B2 (en) | 1997-11-10 | 2005-06-21 | University Of Maryland | Production of novel bovine respiratory syncytial viruses from cDNAs |
| FR2772047B1 (fr) | 1997-12-05 | 2004-04-09 | Ct Nat D Etudes Veterinaires E | Sequence genomique et polypeptides de circovirus associe a la maladie de l'amaigrissement du porcelet (map), applications au diagnostic et a la prevention et/ou au traitement de l'infection |
| FR2775601B1 (fr) * | 1998-03-03 | 2001-09-21 | Merial Sas | Vaccins vivants recombines et adjuves |
| TW440845B (en) | 1999-08-11 | 2001-06-16 | Ibm | Method and system for programming FPGAs on PC-cards without additional hardware |
| US7871598B1 (en) | 2000-05-10 | 2011-01-18 | Novartis Ag | Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use |
| US8404217B2 (en) * | 2000-05-10 | 2013-03-26 | Novartis Ag | Formulation for pulmonary administration of antifungal agents, and associated methods of manufacture and use |
| AU6124601A (en) | 2000-05-10 | 2001-11-20 | Alliance Pharmaceutical Corporation | Phospholipid-based powders for drug delivery |
| US20020106368A1 (en) * | 2000-07-28 | 2002-08-08 | Adrian Bot | Novel methods and compositions to upregulate, redirect or limit immune responses to peptides, proteins and other bioactive compounds and vectors expressing the same |
| US7018638B2 (en) * | 2000-12-19 | 2006-03-28 | Wyeth | Mycoplasma hyopneumoniae bacterin vaccine |
| MY129765A (en) * | 2000-12-19 | 2007-04-30 | Wyeth Corp | Improved mycoplasma hyopneumoniae bacterin vaccine |
| MXPA03010208A (es) | 2001-05-10 | 2004-03-10 | Wyeth Corp | Composicion y metodo para incrementar densidad celular en cultivos celulares infectados con lentivirus. |
| ES2312580T5 (es) | 2001-07-02 | 2017-12-11 | Zoetis Services Llc | Vacunación en dosis única con l Mycoplasma hyopneumoniae /l |
| MXPA04000680A (es) * | 2001-07-27 | 2004-04-05 | Wyeth Corp | Vacuna para virus west nile. |
| US20030129161A1 (en) * | 2001-09-17 | 2003-07-10 | Hsien-Jue Chu | Interleukin-12 as a veterinary vaccine adjuvant |
| KR100958235B1 (ko) | 2001-12-19 | 2010-05-17 | 노바르티스 아게 | 아미노글리코시드의 폐 전달 |
| CN1315534C (zh) * | 2002-08-26 | 2007-05-16 | 辉瑞产品公司 | 用于牛呼吸系统和生殖系统的疫苗 |
| EP1697505A1 (en) * | 2003-12-23 | 2006-09-06 | Schering Corporation | Methods for producing a549 cell lines stable in serum-free medium suspension culture |
| US7833707B2 (en) | 2004-12-30 | 2010-11-16 | Boehringer Ingelheim Vetmedica, Inc. | Methods of overexpression and recovery of porcine circovirus type 2 ORF2 |
| US7700285B1 (en) | 2005-12-29 | 2010-04-20 | Boehringer Ingelheim Vetmedica, Inc. | PCV2 immunogenic compositions and methods of producing such compositions |
| UA95602C2 (ru) | 2004-12-30 | 2011-08-25 | Берингер Ингельхейм Ветмедика, Инк. | Иммуногенная композиция цвс2 и способы приготовления такой композиции |
| US8097288B1 (en) * | 2008-04-16 | 2012-01-17 | Pom Wonderful, Llc | Composition and method for providing nutritional immunology for production animals |
| US20070031342A1 (en) * | 2005-06-22 | 2007-02-08 | Nektar Therapeutics | Sustained release microparticles for pulmonary delivery |
| EP1909839A1 (en) * | 2005-08-04 | 2008-04-16 | Wyeth a Corporation of the State of Delaware | Stabilizers for veterinary vaccines |
| EP2374475A1 (en) | 2005-12-29 | 2011-10-12 | Boehringer Ingelheim Vetmedica, Inc. | Use of a PCV2 immunogenic composition for lessening clinical symptoms in pigs |
| PT1968630T (pt) * | 2005-12-29 | 2018-04-12 | Boehringer Ingelheim Vetmedica Inc | Composições imunogénicas de pcv2 multivalentes |
| EP1911836A1 (en) * | 2006-10-12 | 2008-04-16 | AVIR Green Hills Biotechnology Trading GmbH | Medium supplement for virus production |
| EP2101815A4 (en) | 2006-12-11 | 2010-10-06 | Boehringer Ingelheim Vetmed | EFFICIENT PROCESS FOR THE TREATMENT OF PORCINE CIRCOVIRUS AND LAWSONIA INTRACELLULARIS INFECTIONS |
| AR064363A1 (es) | 2006-12-15 | 2009-04-01 | Boehringer Ingelheim Vetmed | Tratamiento de cerdos con el antigeno pcv |
| EP1941903A1 (en) | 2007-01-03 | 2008-07-09 | Boehringer Ingelheim Vetmedica Gmbh | Prophylaxis and treatment of PRDC |
| EP1958644A1 (en) | 2007-02-13 | 2008-08-20 | Boehringer Ingelheim Vetmedica Gmbh | Prevention and treatment of sub-clinical pcvd |
| US7829274B2 (en) | 2007-09-04 | 2010-11-09 | Boehringer Ingelheim Vetmedica, Inc. | Reduction of concomitant infections in pigs by the use of PCV2 antigen |
| BRPI0907438A2 (pt) | 2008-01-23 | 2015-08-04 | Boehringer Ingelheim Vetmed | Composições imunogênicas para mycoplasma hyopneumoniae e pcv2 e métodos para produzir tais composições |
| TWI627281B (zh) | 2009-09-02 | 2018-06-21 | 百靈佳殷格翰家畜藥品公司 | 降低ｐｃｖ－２組合物殺病毒活性之方法及具有改良免疫原性之ｐｃｖ－２組合物 |
| AU2011352800B2 (en) * | 2010-12-27 | 2015-09-03 | Elanco Us Inc. | Bovine viral diarrhea virus type 1b vaccine compositions and methods |
| AR084358A1 (es) | 2010-12-27 | 2013-05-08 | Lilly Co Eli | Composiciones y metodos para identificar y diferenciar componentes virales de vacunas multivalentes de la “fiebre de embarque” (complejo de enfermedad respiratoria bovina (brdc)) |
| US9120859B2 (en) | 2012-04-04 | 2015-09-01 | Zoetis Services Llc | Mycoplasma hyopneumoniae vaccine |
| UA114504C2 (uk) | 2012-04-04 | 2017-06-26 | Зоетіс Сервісіз Ллс | Комбінована вакцина pcv, mycoplasma hyopneumoniae та prrs |
| UA114503C2 (uk) | 2012-04-04 | 2017-06-26 | Зоетіс Сервісіз Ллс | Комбінована вакцина pcv та mycoplasma hyopneumoniae |
| EP2994162B1 (en) * | 2013-05-08 | 2021-04-07 | Pharmgate Biologics Inc. | Vaccine for pcv2 and mycoplasma |
| MX2016003855A (es) | 2013-09-25 | 2016-08-04 | Zoetis Services Llc | Composicion de vacuna de circovirus porcino tipo 2b divergente y procedimientos de uso. |
| EA035265B1 (ru) | 2013-10-02 | 2020-05-21 | Бёрингер Ингельхайм Энимал Хелс Ю-Эс-Эй Инк. | Вариант белка opc2 pcv2 и содержащие его вирусоподобные частицы |
| JP2021533157A (ja) * | 2018-08-07 | 2021-12-02 | ウィスコンシン アルムニ リサーチ ファンデイション | 組換えの生物学的に封じ込められたフィロウイルスワクチン |
| CN113874496A (zh) | 2019-02-08 | 2021-12-31 | 威斯康星校友研究基金会(Warf) | 人源化细胞系 |
| EP4022046A2 (en) | 2019-08-27 | 2022-07-06 | Wisconsin Alumni Research Foundation (WARF) | Recombinant influenza viruses with stabilized ha for replication in eggs |
| KR20220100681A (ko) * | 2019-11-18 | 2022-07-15 | 엘랑코 유에스 인코포레이티드 | 직벽형 병 내의 동결 건조 케이크 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL8301996A (nl) * | 1983-06-06 | 1985-01-02 | Duphar Int Res | Werkwijze ter bereiding van geadjuveerde levende vaccins en aldus verkregen geadjuveerde levende vaccins. |
| US4772466A (en) * | 1983-08-22 | 1988-09-20 | Syntex (U.S.A.) Inc. | Vaccines comprising polyoxypropylene-polyoxyethylene block polymer based adjuvants |
| US4606918A (en) * | 1983-08-22 | 1986-08-19 | Syntex (U.S.A.) Inc. | Polyoxypropylene-polyoxyethylene block polymer based adjuvants |
| PT1820512E (pt) * | 1994-05-10 | 2013-10-09 | Boehringer Ingelheim Vetmed | Vacina viva modificada melhorada contra brsv |
-
1995
- 1995-05-08 PT PT70083787T patent/PT1820512E/pt unknown
- 1995-05-08 ES ES07008378T patent/ES2429401T3/es not_active Expired - Lifetime
- 1995-05-08 PT PT95918442T patent/PT759780E/pt unknown
- 1995-05-08 ES ES95918442T patent/ES2149361T3/es not_active Expired - Lifetime
- 1995-05-08 SI SI9530731T patent/SI0968722T1/sl unknown
- 1995-05-08 WO PCT/US1995/006053 patent/WO1995030437A1/en active IP Right Grant
- 1995-05-08 SI SI9530374T patent/SI0759780T1/xx unknown
- 1995-05-08 AU AU24387/95A patent/AU711350B2/en not_active Expired
- 1995-05-08 AT AT95918442T patent/ATE195255T1/de active
- 1995-05-08 MY MYPI95001214A patent/MY111829A/en unknown
- 1995-05-08 DE DE69535520T patent/DE69535520T2/de not_active Expired - Lifetime
- 1995-05-08 KR KR1019960706404A patent/KR100374434B1/ko not_active IP Right Cessation
- 1995-05-08 DE DE69518316T patent/DE69518316T2/de not_active Expired - Lifetime
- 1995-05-08 CN CNB951939424A patent/CN1268393C/zh not_active Expired - Lifetime
- 1995-05-08 DK DK95918442T patent/DK0759780T3/da active
- 1995-05-08 DK DK99115633T patent/DK0968722T3/da active
- 1995-05-08 ES ES99115633T patent/ES2287997T3/es not_active Expired - Lifetime
- 1995-05-08 PT PT99115633T patent/PT968722E/pt unknown
- 1995-05-08 EP EP99115633A patent/EP0968722B1/en not_active Expired - Lifetime
- 1995-05-08 BR BR9507717A patent/BR9507717A/pt not_active IP Right Cessation
- 1995-05-08 JP JP52920895A patent/JP3993230B2/ja not_active Expired - Lifetime
- 1995-05-08 EP EP07008378.7A patent/EP1820512B1/en not_active Expired - Lifetime
- 1995-05-08 AT AT99115633T patent/ATE365049T1/de active
- 1995-05-08 CA CA2189979A patent/CA2189979C/en not_active Expired - Lifetime
- 1995-05-08 NZ NZ285324A patent/NZ285324A/en not_active IP Right Cessation
- 1995-05-08 EP EP07007405A patent/EP1844791A1/en not_active Withdrawn
- 1995-05-08 ZA ZA953703A patent/ZA953703B/xx unknown
- 1995-05-08 EP EP95918442A patent/EP0759780B1/en not_active Expired - Lifetime
-
1996
- 1996-04-25 US US08/638,879 patent/US5733555A/en not_active Expired - Lifetime
-
1997
- 1997-12-18 US US08/993,400 patent/US5958423A/en not_active Expired - Lifetime
-
2000
- 2000-06-21 HK HK00103769A patent/HK1024412A1/xx not_active IP Right Cessation
- 2000-09-13 GR GR20000402092T patent/GR3034402T3/el unknown
-
2007
- 2007-03-07 JP JP2007057402A patent/JP2007137905A/ja not_active Withdrawn
-
2011
- 2011-08-26 JP JP2011184908A patent/JP2011246489A/ja active Pending
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