SI0656211T1 - Stable lyophilized thiotepa composition - Google Patents

Stable lyophilized thiotepa composition

Info

Publication number
SI0656211T1
SI0656211T1 SI9430237T SI9430237T SI0656211T1 SI 0656211 T1 SI0656211 T1 SI 0656211T1 SI 9430237 T SI9430237 T SI 9430237T SI 9430237 T SI9430237 T SI 9430237T SI 0656211 T1 SI0656211 T1 SI 0656211T1
Authority
SI
Slovenia
Prior art keywords
stable lyophilized
composition
thiotepa composition
lyophilized thiotepa
stable
Prior art date
Application number
SI9430237T
Other languages
English (en)
Slovenian (sl)
Inventor
Mannching S. Ku
Jorge Velez
Joe Hoffman
Lourdes Zamora
Original Assignee
American Cyanamid Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Company filed Critical American Cyanamid Company
Publication of SI0656211T1 publication Critical patent/SI0656211T1/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/675Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Dermatology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SI9430237T 1993-11-09 1994-11-09 Stable lyophilized thiotepa composition SI0656211T1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US15050193A 1993-11-09 1993-11-09
EP94117666A EP0656211B1 (en) 1993-11-09 1994-11-09 Stable lyophilized thiotepa composition

Publications (1)

Publication Number Publication Date
SI0656211T1 true SI0656211T1 (en) 1999-08-31

Family

ID=22534834

Family Applications (1)

Application Number Title Priority Date Filing Date
SI9430237T SI0656211T1 (en) 1993-11-09 1994-11-09 Stable lyophilized thiotepa composition

Country Status (29)

Country Link
US (1) US5561121A (ru)
EP (1) EP0656211B1 (ru)
JP (1) JP3726255B2 (ru)
KR (1) KR100348382B1 (ru)
CN (1) CN1111130A (ru)
AR (1) AR023045A2 (ru)
AT (1) ATE180670T1 (ru)
AU (1) AU690143B2 (ru)
CA (1) CA2135265A1 (ru)
CZ (1) CZ287052B6 (ru)
DE (1) DE69418832T2 (ru)
DK (1) DK0656211T3 (ru)
ES (1) ES2133152T3 (ru)
FI (1) FI116036B (ru)
GR (1) GR3031122T3 (ru)
HK (1) HK1011283A1 (ru)
HU (1) HU218216B (ru)
IL (1) IL111534A (ru)
NO (1) NO305274B1 (ru)
NZ (1) NZ264861A (ru)
PE (1) PE22995A1 (ru)
PH (1) PH31219A (ru)
PL (1) PL176984B1 (ru)
RU (1) RU2134112C1 (ru)
SG (1) SG63584A1 (ru)
SI (1) SI0656211T1 (ru)
SK (1) SK280840B6 (ru)
TW (1) TW344662B (ru)
ZA (1) ZA948833B (ru)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9726343D0 (en) * 1997-12-13 1998-02-11 Auffret Anthony The use of excipients to accelerate freeze-drying
EP1399131A2 (en) * 2001-06-08 2004-03-24 Powderject Vaccines, Inc. Spray freeze-dried compositions
US8436190B2 (en) 2005-01-14 2013-05-07 Cephalon, Inc. Bendamustine pharmaceutical compositions
US8158152B2 (en) * 2005-11-18 2012-04-17 Scidose Llc Lyophilization process and products obtained thereby
AR072777A1 (es) 2008-03-26 2010-09-22 Cephalon Inc Formas solidas de clorhidrato de bendamustina
EP2889029A1 (en) 2008-09-25 2015-07-01 Cephalon, Inc. Liquid formulations of bendamustine
SG172810A1 (en) 2009-01-15 2011-08-29 Cephalon Inc Novel forms of bendamustine free base
WO2013049021A1 (en) * 2011-09-29 2013-04-04 Janssen Pharmaceutica Nv Process for the preparation of sulfamide derivatives
CN104349417B (zh) * 2013-08-07 2017-11-21 中国科学院声学研究所 基于短生命周期的区域性水下通信网的组网方法
WO2018227112A1 (en) * 2017-06-09 2018-12-13 The Trustees Of Columbia University In The City Of New York Short tat oligomers for drug delivery
CN109956972A (zh) * 2017-12-22 2019-07-02 四川科瑞德凯华制药有限公司 塞替派晶型i及其制备方法和用途
CN110917146A (zh) * 2019-12-03 2020-03-27 黑龙江福和制药集团股份有限公司 一种塞替派粉针及其制备方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2670347A (en) * 1952-01-08 1954-02-23 American Cyanamid Co Thiophosphoric acid derivatives and method of preparing the same
GB845823A (en) * 1957-09-19 1960-08-24 Sumitomo Chemical Co Stabilised compositions comprising therapeutic imine derivatives and the preparation thereof
DE1951822C3 (de) * 1969-10-14 1980-12-11 Kowa Co., Ltd., Nagoya, Aichi (Japan) Pharmazeutisches Präparat zur Krebsbehandlung
DE2925009A1 (de) * 1979-06-21 1981-01-08 Basf Ag Zubereitung fuer substanzen, verfahren zu deren herstellung und deren verwendung
EP0120907A1 (en) * 1982-10-13 1984-10-10 Aston Molecules Limited Pharmaceutical preparations for use in antitumour therapy
EP0140255B1 (en) * 1983-10-14 1991-05-15 Sumitomo Pharmaceuticals Company, Limited Sustained-release injections
CH676508A5 (ru) * 1986-10-13 1991-01-31 Anawa Lab Ag
US4918199A (en) * 1988-01-21 1990-04-17 American Cyanamid Company Process for producing thiotepa
US5122367A (en) * 1989-03-31 1992-06-16 Massachusetts Institute Of Technology Polyanhydride bioerodible controlled release implants for administration of stabilized growth hormone
EP0419890A3 (en) * 1989-09-29 1991-05-29 American Cyanamid Company Stable pharmaceutical formulations for antineoplastic compounds having more than one ethyleneimine group, and method

Also Published As

Publication number Publication date
ZA948833B (en) 1995-07-14
DE69418832T2 (de) 1999-09-23
NO944256L (no) 1995-05-10
GR3031122T3 (en) 1999-12-31
SG63584A1 (en) 1999-03-30
PL305752A1 (en) 1995-05-15
JP3726255B2 (ja) 2005-12-14
HUT70762A (en) 1995-10-30
AR023045A2 (es) 2002-09-04
AU7768994A (en) 1995-05-18
RU2134112C1 (ru) 1999-08-10
EP0656211B1 (en) 1999-06-02
AU690143B2 (en) 1998-04-23
CA2135265A1 (en) 1995-05-10
KR100348382B1 (ko) 2002-11-23
NO944256D0 (no) 1994-11-08
NO305274B1 (no) 1999-05-03
IL111534A (en) 1999-06-20
HU218216B (hu) 2000-06-28
PE22995A1 (es) 1995-09-08
HK1011283A1 (en) 1999-07-09
IL111534A0 (en) 1995-01-24
TW344662B (en) 1998-11-11
FI945252A (fi) 1995-05-10
EP0656211A1 (en) 1995-06-07
CN1111130A (zh) 1995-11-08
PH31219A (en) 1998-05-05
RU94040150A (ru) 1996-09-20
ES2133152T3 (es) 1999-09-01
SK280840B6 (sk) 2000-08-14
DK0656211T3 (da) 1999-11-15
FI945252A0 (fi) 1994-11-08
CZ271894A3 (en) 1995-07-12
JPH07196517A (ja) 1995-08-01
ATE180670T1 (de) 1999-06-15
CZ287052B6 (en) 2000-08-16
NZ264861A (en) 1995-10-26
PL176984B1 (pl) 1999-08-31
US5561121A (en) 1996-10-01
FI116036B (fi) 2005-09-15
DE69418832D1 (de) 1999-07-08
SK135294A3 (en) 1996-01-10
HU9403210D0 (en) 1995-01-30

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