SG80628A1 - A process for the preparation of 13-cis-retinoic acid - Google Patents

A process for the preparation of 13-cis-retinoic acid

Info

Publication number
SG80628A1
SG80628A1 SG9902501A SG1999002501A SG80628A1 SG 80628 A1 SG80628 A1 SG 80628A1 SG 9902501 A SG9902501 A SG 9902501A SG 1999002501 A SG1999002501 A SG 1999002501A SG 80628 A1 SG80628 A1 SG 80628A1
Authority
SG
Singapore
Prior art keywords
cis
retinoic acid
preparation
vinyl
ionol
Prior art date
Application number
SG9902501A
Other languages
English (en)
Inventor
Grato Magnone
Original Assignee
Lab Mag Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lab Mag Spa filed Critical Lab Mag Spa
Publication of SG80628A1 publication Critical patent/SG80628A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
    • C07C403/20—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by carboxyl groups or halides, anhydrides, or (thio)esters thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/10—Anti-acne agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/09—Geometrical isomers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyrane Compounds (AREA)
SG9902501A 1998-05-19 1999-05-19 A process for the preparation of 13-cis-retinoic acid SG80628A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT98MI001093A IT1299582B1 (it) 1998-05-19 1998-05-19 Procedimento per la preparazione dell'acido 13-cis-retinoico

Publications (1)

Publication Number Publication Date
SG80628A1 true SG80628A1 (en) 2001-05-22

Family

ID=11380052

Family Applications (1)

Application Number Title Priority Date Filing Date
SG9902501A SG80628A1 (en) 1998-05-19 1999-05-19 A process for the preparation of 13-cis-retinoic acid

Country Status (16)

Country Link
US (1) US6177579B1 (es)
EP (1) EP0959069B1 (es)
JP (1) JP4418048B2 (es)
AT (1) ATE226190T1 (es)
BR (1) BR9901551B1 (es)
CA (1) CA2272439C (es)
DE (1) DE69903498T2 (es)
DK (1) DK0959069T3 (es)
ES (1) ES2185263T3 (es)
HU (1) HU229518B1 (es)
IN (1) IN188476B (es)
IT (1) IT1299582B1 (es)
NO (1) NO317759B1 (es)
PL (1) PL192958B1 (es)
SG (1) SG80628A1 (es)
ZA (1) ZA993395B (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7763748B2 (en) * 2007-02-20 2010-07-27 Ipca Laboratories Limited Process for preparation of highly pure isotretinoin
CN104447459A (zh) * 2014-11-28 2015-03-25 重庆华邦制药有限公司 异维a酸的新晶型及其制备方法与应用
CN111454141A (zh) * 2020-04-26 2020-07-28 上海新华联制药有限公司 一种异维a酸缩合物及其制备方法和应用
CN116283495A (zh) * 2021-12-01 2023-06-23 万华化学集团股份有限公司 一种乙烯基-β-紫罗兰醇的制备方法
CN116462621A (zh) * 2023-02-20 2023-07-21 湖北恒安芙林药业股份有限公司 一种维a酸的制备方法

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3200231A1 (de) * 1982-01-07 1983-07-21 Basf Ag, 6700 Ludwigshafen (alpha)-pyrone und verfahren zur herstellung von polyencarbonsaeuren
DE4313089A1 (de) * 1993-04-22 1994-10-27 Basf Ag Verfahren zur Herstellung von 13-(Z)-Retinsäure
EP0850925A1 (en) * 1996-12-27 1998-07-01 LABORATORI MAG S.p.A. Process for preparation of 13-cis-retinoic acid

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3200231A1 (de) * 1982-01-07 1983-07-21 Basf Ag, 6700 Ludwigshafen (alpha)-pyrone und verfahren zur herstellung von polyencarbonsaeuren
DE4313089A1 (de) * 1993-04-22 1994-10-27 Basf Ag Verfahren zur Herstellung von 13-(Z)-Retinsäure
EP0850925A1 (en) * 1996-12-27 1998-07-01 LABORATORI MAG S.p.A. Process for preparation of 13-cis-retinoic acid

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
G. PATTENDEN ET AL: J. CHEM. SOC. (C), 1968, pages 1984-1997, XP002110253 *

Also Published As

Publication number Publication date
NO992396L (no) 1999-11-22
DK0959069T3 (da) 2003-02-24
ATE226190T1 (de) 2002-11-15
DE69903498D1 (de) 2002-11-21
BR9901551A (pt) 2000-05-30
NO992396D0 (no) 1999-05-19
IT1299582B1 (it) 2000-03-16
US6177579B1 (en) 2001-01-23
IN188476B (es) 2002-09-28
EP0959069A1 (en) 1999-11-24
ZA993395B (en) 1999-11-18
CA2272439C (en) 2010-05-11
EP0959069B1 (en) 2002-10-16
CA2272439A1 (en) 1999-11-19
PL192958B1 (pl) 2006-12-29
HU229518B1 (hu) 2014-01-28
HU9901651D0 (en) 1999-07-28
HUP9901651A2 (hu) 1999-12-28
DE69903498T2 (de) 2003-02-27
NO317759B1 (no) 2004-12-13
HUP9901651A3 (en) 2000-06-28
BR9901551B1 (pt) 2010-10-19
ES2185263T3 (es) 2003-04-16
JP2000034275A (ja) 2000-02-02
PL333200A1 (en) 1999-11-22
ITMI981093A1 (it) 1999-11-19
JP4418048B2 (ja) 2010-02-17

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