SG192706A1 - Cells and methods for producing isobutyric acid - Google Patents

Cells and methods for producing isobutyric acid Download PDF

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Publication number
SG192706A1
SG192706A1 SG2013060769A SG2013060769A SG192706A1 SG 192706 A1 SG192706 A1 SG 192706A1 SG 2013060769 A SG2013060769 A SG 2013060769A SG 2013060769 A SG2013060769 A SG 2013060769A SG 192706 A1 SG192706 A1 SG 192706A1
Authority
SG
Singapore
Prior art keywords
cell
polypeptide
genetically modified
isobutyrate
recombinant cell
Prior art date
Application number
SG2013060769A
Other languages
English (en)
Inventor
Kechun Zhang
Mingyong Xiong
Adam P Woodruff
Original Assignee
Univ Minnesota
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Minnesota filed Critical Univ Minnesota
Publication of SG192706A1 publication Critical patent/SG192706A1/en

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14—Fungi; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0008—Oxidoreductases (1.) acting on the aldehyde or oxo group of donors (1.2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/52—Propionic acid; Butyric acids

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Botany (AREA)
  • Mycology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
SG2013060769A 2011-02-11 2012-02-10 Cells and methods for producing isobutyric acid SG192706A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161441939P 2011-02-11 2011-02-11
PCT/US2012/024640 WO2012109534A2 (en) 2011-02-11 2012-02-10 Cells and methods for producing isobutyric acid

Publications (1)

Publication Number Publication Date
SG192706A1 true SG192706A1 (en) 2013-09-30

Family

ID=45722726

Family Applications (1)

Application Number Title Priority Date Filing Date
SG2013060769A SG192706A1 (en) 2011-02-11 2012-02-10 Cells and methods for producing isobutyric acid

Country Status (8)

Country Link
US (1) US20140065697A1 (https=)
EP (1) EP2673355A2 (https=)
JP (1) JP2014506466A (https=)
KR (1) KR20140061303A (https=)
CN (1) CN103562375A (https=)
AU (1) AU2012214255A1 (https=)
SG (1) SG192706A1 (https=)
WO (1) WO2012109534A2 (https=)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013055667A2 (en) * 2011-10-10 2013-04-18 Regents Of The University Of Minnesota Biocatalysis cells and methods
CN104685059A (zh) * 2012-05-29 2015-06-03 明尼苏达大学评议会 生物合成途径、重组细胞和方法
WO2013192237A1 (en) * 2012-06-18 2013-12-27 The Regents Of The University Of California Escherichia coli engineered for isobutyraldehyde production
WO2014028642A1 (en) 2012-08-17 2014-02-20 Easel Biotechnologies, Llc Two stage production of higher alcohols
CN105705650A (zh) * 2013-08-28 2016-06-22 英威达技术有限责任公司 用于生物合成异丁烯酸盐的方法
JP2017131111A (ja) 2014-06-03 2017-08-03 味の素株式会社 Ｌ−アミノ酸の製造法
WO2015191611A1 (en) * 2014-06-09 2015-12-17 The Regents Of The University Of California Bacteria engineered for conversion of ethylene to n-butanol
AU2016265751A1 (en) 2015-05-19 2017-12-14 Lucite International Uk Limited Process for the biological production of methacrylic acid and derivatives thereof
CN105296410A (zh) * 2015-10-27 2016-02-03 中国科学院青岛生物能源与过程研究所 一种利用缬氨酸途径合成丙烷的大肠杆菌及其构建方法
US20200308610A1 (en) 2016-03-11 2020-10-01 Aemitis, Inc. Alpha-ketoisocaproic acid and & alpha-keto-3-methylvaleric acid decarboxylases and uses thereof
WO2017194696A1 (en) 2016-05-12 2017-11-16 Danmarks Tekniske Universitet Bacterial cells with improved tolerance to isobutyric acid
US10849938B2 (en) 2017-09-13 2020-12-01 ZBiotics Company Gene expression system for probiotic microorganisms
US11680280B2 (en) 2018-01-09 2023-06-20 Lygos, Inc. Recombinant host cells and methods for the production of isobutyric acid

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0031886B1 (de) * 1979-12-20 1984-04-11 Röhm Gmbh Verfahren zur Herstellung von Isobuttersäure oder ihrer niederen Alkylester
US4754074A (en) 1986-12-22 1988-06-28 Amoco Corporation Preparation of dialkyl ketones from aliphatic carboxylic acids
US20090053797A1 (en) * 2005-08-19 2009-02-26 Yoichiro Shiba Genetically modified host cells and use of same for producing isoprenoid compounds
KR100780324B1 (ko) * 2006-07-28 2007-11-29 한국과학기술원 신규 순수 숙신산 생성 변이 미생물 및 이를 이용한 숙신산제조방법
KR20100031525A (ko) * 2007-06-01 2010-03-22 에보니크 룀 게엠베하 메타크릴산 또는 메타크릴산 에스테르의 제조 방법
US20110281314A1 (en) * 2008-08-04 2011-11-17 Lynch Michael D Methods, systems and compositions related to microbial bio-production of butanol and/or isobutanol
EP2350299A4 (en) * 2008-10-28 2012-04-25 Univ Rice William M MICROAEROBE CULTURES FOR THE CONVERSION OF GLYCERINE IN CHEMICALS
BR112012020261B8 (pt) * 2010-02-12 2020-04-14 California Inst Of Techn saccharomyces cerevisiae recombinante e método de produção de isobutanol

Also Published As

Publication number Publication date
WO2012109534A3 (en) 2012-10-04
EP2673355A2 (en) 2013-12-18
KR20140061303A (ko) 2014-05-21
AU2012214255A1 (en) 2013-09-12
WO2012109534A2 (en) 2012-08-16
US20140065697A1 (en) 2014-03-06
CN103562375A (zh) 2014-02-05
JP2014506466A (ja) 2014-03-17

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