KR20140061303A - 이소부티르산을 생산하기 위한 세포 및 방법 - Google Patents

이소부티르산을 생산하기 위한 세포 및 방법 Download PDF

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KR20140061303A
KR20140061303A KR1020137023666A KR20137023666A KR20140061303A KR 20140061303 A KR20140061303 A KR 20140061303A KR 1020137023666 A KR1020137023666 A KR 1020137023666A KR 20137023666 A KR20137023666 A KR 20137023666A KR 20140061303 A KR20140061303 A KR 20140061303A
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gly
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커춘 장
밍융 슝
아담 피. 우드러프
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리전츠 오브 더 유니버스티 오브 미네소타
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Publication of KR20140061303A publication Critical patent/KR20140061303A/ko
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14—Fungi; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0008—Oxidoreductases (1.) acting on the aldehyde or oxo group of donors (1.2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/52—Propionic acid; Butyric acids

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Botany (AREA)
  • Mycology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
KR1020137023666A 2011-02-11 2012-02-10 이소부티르산을 생산하기 위한 세포 및 방법 Withdrawn KR20140061303A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161441939P 2011-02-11 2011-02-11
US61/441,939 2011-02-11
PCT/US2012/024640 WO2012109534A2 (en) 2011-02-11 2012-02-10 Cells and methods for producing isobutyric acid

Publications (1)

Publication Number Publication Date
KR20140061303A true KR20140061303A (ko) 2014-05-21

Family

ID=45722726

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020137023666A Withdrawn KR20140061303A (ko) 2011-02-11 2012-02-10 이소부티르산을 생산하기 위한 세포 및 방법

Country Status (8)

Country Link
US (1) US20140065697A1 (https=)
EP (1) EP2673355A2 (https=)
JP (1) JP2014506466A (https=)
KR (1) KR20140061303A (https=)
CN (1) CN103562375A (https=)
AU (1) AU2012214255A1 (https=)
SG (1) SG192706A1 (https=)
WO (1) WO2012109534A2 (https=)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013055667A2 (en) * 2011-10-10 2013-04-18 Regents Of The University Of Minnesota Biocatalysis cells and methods
CN104685059A (zh) * 2012-05-29 2015-06-03 明尼苏达大学评议会 生物合成途径、重组细胞和方法
WO2013192237A1 (en) * 2012-06-18 2013-12-27 The Regents Of The University Of California Escherichia coli engineered for isobutyraldehyde production
WO2014028642A1 (en) 2012-08-17 2014-02-20 Easel Biotechnologies, Llc Two stage production of higher alcohols
CN105705650A (zh) * 2013-08-28 2016-06-22 英威达技术有限责任公司 用于生物合成异丁烯酸盐的方法
JP2017131111A (ja) 2014-06-03 2017-08-03 味の素株式会社 Ｌ−アミノ酸の製造法
WO2015191611A1 (en) * 2014-06-09 2015-12-17 The Regents Of The University Of California Bacteria engineered for conversion of ethylene to n-butanol
AU2016265751A1 (en) 2015-05-19 2017-12-14 Lucite International Uk Limited Process for the biological production of methacrylic acid and derivatives thereof
CN105296410A (zh) * 2015-10-27 2016-02-03 中国科学院青岛生物能源与过程研究所 一种利用缬氨酸途径合成丙烷的大肠杆菌及其构建方法
US20200308610A1 (en) 2016-03-11 2020-10-01 Aemitis, Inc. Alpha-ketoisocaproic acid and & alpha-keto-3-methylvaleric acid decarboxylases and uses thereof
WO2017194696A1 (en) 2016-05-12 2017-11-16 Danmarks Tekniske Universitet Bacterial cells with improved tolerance to isobutyric acid
US10849938B2 (en) 2017-09-13 2020-12-01 ZBiotics Company Gene expression system for probiotic microorganisms
US11680280B2 (en) 2018-01-09 2023-06-20 Lygos, Inc. Recombinant host cells and methods for the production of isobutyric acid

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0031886B1 (de) * 1979-12-20 1984-04-11 Röhm Gmbh Verfahren zur Herstellung von Isobuttersäure oder ihrer niederen Alkylester
US4754074A (en) 1986-12-22 1988-06-28 Amoco Corporation Preparation of dialkyl ketones from aliphatic carboxylic acids
US20090053797A1 (en) * 2005-08-19 2009-02-26 Yoichiro Shiba Genetically modified host cells and use of same for producing isoprenoid compounds
KR100780324B1 (ko) * 2006-07-28 2007-11-29 한국과학기술원 신규 순수 숙신산 생성 변이 미생물 및 이를 이용한 숙신산제조방법
KR20100031525A (ko) * 2007-06-01 2010-03-22 에보니크 룀 게엠베하 메타크릴산 또는 메타크릴산 에스테르의 제조 방법
US20110281314A1 (en) * 2008-08-04 2011-11-17 Lynch Michael D Methods, systems and compositions related to microbial bio-production of butanol and/or isobutanol
EP2350299A4 (en) * 2008-10-28 2012-04-25 Univ Rice William M MICROAEROBE CULTURES FOR THE CONVERSION OF GLYCERINE IN CHEMICALS
BR112012020261B8 (pt) * 2010-02-12 2020-04-14 California Inst Of Techn saccharomyces cerevisiae recombinante e método de produção de isobutanol

Also Published As

Publication number Publication date
WO2012109534A3 (en) 2012-10-04
EP2673355A2 (en) 2013-12-18
SG192706A1 (en) 2013-09-30
AU2012214255A1 (en) 2013-09-12
WO2012109534A2 (en) 2012-08-16
US20140065697A1 (en) 2014-03-06
CN103562375A (zh) 2014-02-05
JP2014506466A (ja) 2014-03-17

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PA0105 International application

Patent event date: 20130906

Patent event code: PA01051R01D

Comment text: International Patent Application

PG1501 Laying open of application
PC1203 Withdrawal of no request for examination
WITN Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid