SG189427A1 - 23-yne-vitamin d3 derivative - Google Patents
23-yne-vitamin d3 derivative Download PDFInfo
- Publication number
- SG189427A1 SG189427A1 SG2013028584A SG2013028584A SG189427A1 SG 189427 A1 SG189427 A1 SG 189427A1 SG 2013028584 A SG2013028584 A SG 2013028584A SG 2013028584 A SG2013028584 A SG 2013028584A SG 189427 A1 SG189427 A1 SG 189427A1
- Authority
- SG
- Singapore
- Prior art keywords
- group
- yne
- seco
- cholestatriene
- vitamin
- Prior art date
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Classifications
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- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
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- C—CHEMISTRY; METALLURGY
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- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B61/00—Other general methods
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
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- C07F7/1804—Compounds having Si-O-C linkages
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- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
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- C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
- C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
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- C—CHEMISTRY; METALLURGY
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- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
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- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
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- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Physical Education & Sports Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
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- Orthopedic Medicine & Surgery (AREA)
- Pulmonology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2010238524 | 2010-10-25 | ||
| PCT/JP2011/074414 WO2012057068A1 (ja) | 2010-10-25 | 2011-10-24 | ２３－イン－ビタミンｄ３誘導体 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG189427A1 true SG189427A1 (en) | 2013-05-31 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG2013028584A SG189427A1 (en) | 2010-10-25 | 2011-10-24 | 23-yne-vitamin d3 derivative |
Country Status (21)
| Country | Link |
|---|---|
| US (2) | US9006220B2 (pt) |
| EP (1) | EP2634171B8 (pt) |
| JP (1) | JP5738307B2 (pt) |
| KR (1) | KR101853518B1 (pt) |
| CN (2) | CN104829510B (pt) |
| AR (1) | AR083541A1 (pt) |
| AU (1) | AU2011321624B2 (pt) |
| BR (1) | BR112013009647A2 (pt) |
| CA (1) | CA2815501C (pt) |
| DK (1) | DK2634171T3 (pt) |
| ES (1) | ES2541719T3 (pt) |
| HK (2) | HK1184133A1 (pt) |
| HU (1) | HUE025554T2 (pt) |
| IL (1) | IL225630A0 (pt) |
| MX (1) | MX347126B (pt) |
| PL (1) | PL2634171T3 (pt) |
| PT (1) | PT2634171E (pt) |
| RU (1) | RU2558362C2 (pt) |
| SG (1) | SG189427A1 (pt) |
| TW (1) | TWI503120B (pt) |
| WO (1) | WO2012057068A1 (pt) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2013162047A1 (ja) * | 2012-04-24 | 2013-10-31 | 帝人ファーマ株式会社 | 二次性副甲状腺機能亢進症治療剤 |
| JP2020143008A (ja) * | 2019-03-05 | 2020-09-10 | 達也 楠堂 | 新規褐色脂肪細胞分化誘導剤 |
| CN114681467B (zh) * | 2022-03-30 | 2024-03-12 | 南通华山药业有限公司 | 一种阿法骨化醇杂环酯类衍生物在制备抗肿瘤药物中的应用 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4804502A (en) * | 1988-01-20 | 1989-02-14 | Hoffmann-La Roche Inc. | Vitamin D compounds |
| GB9017890D0 (en) * | 1990-08-15 | 1990-09-26 | Leo Pharm Prod Ltd | Chemical compounds i |
| AU666563B2 (en) * | 1992-08-07 | 1996-02-15 | Wisconsin Alumni Research Foundation | Preparation of 19-nor-vitamin D compounds |
| SG70009A1 (en) * | 1996-05-23 | 2000-01-25 | Hoffmann La Roche | Vitamin d3 analogs |
| SG70010A1 (en) * | 1996-05-23 | 2000-01-25 | Hoffmann La Roche | Fluorinated vitamin d3 analogs |
| GB9611603D0 (en) * | 1996-06-04 | 1996-08-07 | Leo Pharm Prod Ltd | Chemical compounds |
| CA2263940A1 (en) | 1997-06-25 | 1998-12-30 | Teijin Limited | Vitamin d3 derivatives and remedies for inflammatory respiratory diseases prepared from the same |
| US5939406A (en) * | 1997-07-21 | 1999-08-17 | Wisconsin Alumni Research Foundation | 18-substituted-19-nor-vitamin D compounds |
| US6359152B2 (en) * | 1997-07-21 | 2002-03-19 | Wisconsin Alumni Research Foundation | 18-substituted-19-nor-vitamin D compounds |
| DE69939106D1 (de) * | 1998-02-24 | 2008-08-28 | Chugai Pharmaceutical Co Ltd | Verfahren zur Herstellung von ED-71 |
| US6538145B2 (en) * | 1998-02-24 | 2003-03-25 | Chugai Seiyaku Kabushiki Kaisha | 24-hydroxy vitamin D derivatives |
| EP1070704A4 (en) * | 1998-04-10 | 2001-11-07 | Chugai Pharmaceutical Co Ltd | VITAMIN D DERIVATIVES SUBSTITUTED IN THE 2 BETA POSITION |
| AU2001234189A1 (en) * | 2000-02-28 | 2001-09-03 | Chugai Seiyaku Kabushiki Kaisha | Vitamin d derivatives having substituents at the 2alpha-position |
| JP2008514621A (ja) * | 2004-09-24 | 2008-05-08 | ビオクセル エッセ ピ ア | ２０−シクロアルキル，２６，２７−アルキル／ハロアルキル−ビタミンｄ３化合物及びその使用方法 |
| JP2009013154A (ja) * | 2006-09-29 | 2009-01-22 | Teijin Pharma Ltd | ２−置換−１４−エピ−プレビタミンｄ３誘導体 |
-
2011
- 2011-10-24 BR BR112013009647A patent/BR112013009647A2/pt not_active Application Discontinuation
- 2011-10-24 AU AU2011321624A patent/AU2011321624B2/en not_active Ceased
- 2011-10-24 AR ARP110103926A patent/AR083541A1/es not_active Application Discontinuation
- 2011-10-24 US US13/880,637 patent/US9006220B2/en not_active Expired - Fee Related
- 2011-10-24 TW TW100138462A patent/TWI503120B/zh not_active IP Right Cessation
- 2011-10-24 DK DK11836202.9T patent/DK2634171T3/en active
- 2011-10-24 PT PT118362029T patent/PT2634171E/pt unknown
- 2011-10-24 SG SG2013028584A patent/SG189427A1/en unknown
- 2011-10-24 MX MX2013004389A patent/MX347126B/es active IP Right Grant
- 2011-10-24 ES ES11836202.9T patent/ES2541719T3/es active Active
- 2011-10-24 PL PL11836202T patent/PL2634171T3/pl unknown
- 2011-10-24 CN CN201510228060.3A patent/CN104829510B/zh not_active Expired - Fee Related
- 2011-10-24 EP EP11836202.9A patent/EP2634171B8/en active Active
- 2011-10-24 KR KR1020137010316A patent/KR101853518B1/ko active IP Right Grant
- 2011-10-24 RU RU2013124033/04A patent/RU2558362C2/ru not_active IP Right Cessation
- 2011-10-24 JP JP2012540840A patent/JP5738307B2/ja not_active Expired - Fee Related
- 2011-10-24 CA CA2815501A patent/CA2815501C/en not_active Expired - Fee Related
- 2011-10-24 WO PCT/JP2011/074414 patent/WO2012057068A1/ja active Application Filing
- 2011-10-24 HU HUE11836202A patent/HUE025554T2/en unknown
- 2011-10-24 CN CN201180051519.7A patent/CN103180293B/zh not_active Expired - Fee Related
-
2013
- 2013-04-08 IL IL225630A patent/IL225630A0/en unknown
- 2013-10-10 HK HK13111437.3A patent/HK1184133A1/xx not_active IP Right Cessation
-
2015
- 2015-02-03 US US14/612,781 patent/US9079843B2/en not_active Expired - Fee Related
- 2015-12-07 HK HK15112013.1A patent/HK1211281A1/zh not_active IP Right Cessation
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