SG173558A1 - Derivatives of 6-(6-o-cycloalkyl or 6-nh-cycloalkyl-triazolopyridazine-sulfanyl) benzothiazoles and benzimidazoles, preparation thereof, use thereof as drugs, and use thereof as met inhibitors - Google Patents
Derivatives of 6-(6-o-cycloalkyl or 6-nh-cycloalkyl-triazolopyridazine-sulfanyl) benzothiazoles and benzimidazoles, preparation thereof, use thereof as drugs, and use thereof as met inhibitors Download PDFInfo
- Publication number
- SG173558A1 SG173558A1 SG2011056470A SG2011056470A SG173558A1 SG 173558 A1 SG173558 A1 SG 173558A1 SG 2011056470 A SG2011056470 A SG 2011056470A SG 2011056470 A SG2011056470 A SG 2011056470A SG 173558 A1 SG173558 A1 SG 173558A1
- Authority
- SG
- Singapore
- Prior art keywords
- benzothiazol
- radical
- triazolo
- pyridazin
- sulfanyl
- Prior art date
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Classifications
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- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
- C07D277/62—Benzothiazoles
- C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D277/82—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Neurology (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Neurosurgery (AREA)
- Pulmonology (AREA)
- Obesity (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Cardiology (AREA)
- Ophthalmology & Optometry (AREA)
- Pain & Pain Management (AREA)
- Endocrinology (AREA)
- Heart & Thoracic Surgery (AREA)
- Psychiatry (AREA)
- Emergency Medicine (AREA)
- Oncology (AREA)
- Dermatology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0900510A FR2941949B1 (fr) | 2009-02-06 | 2009-02-06 | Derives de 6-(6-o-cycloalkyl ou 6-nh-cycloalkyl- triazolopyridazine-sulfanyl)benzothiazoles et benzimidazoles preparation, application comme medicaments et utilisation comme inhibiteurs de met. |
| PCT/FR2010/050177 WO2010089506A1 (fr) | 2009-02-06 | 2010-02-04 | Derives de 6-(6-o-cycloalkyl ou 6-nh-cycloalkyl-triazolopyridazine-sulfanyl) benzothiazoles et benzimidazoles : preparation, application comme medicaments et utilisation comme inhibiteurs de met |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG173558A1 true SG173558A1 (en) | 2011-09-29 |
Family
ID=40863635
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG2011056470A SG173558A1 (en) | 2009-02-06 | 2010-02-04 | Derivatives of 6-(6-o-cycloalkyl or 6-nh-cycloalkyl-triazolopyridazine-sulfanyl) benzothiazoles and benzimidazoles, preparation thereof, use thereof as drugs, and use thereof as met inhibitors |
Country Status (18)
| Country | Link |
|---|---|
| EP (1) | EP2393790A1 (ko) |
| JP (1) | JP2012517407A (ko) |
| KR (1) | KR20110126660A (ko) |
| CN (1) | CN102388029A (ko) |
| AR (1) | AR075248A1 (ko) |
| AU (1) | AU2010212231A1 (ko) |
| BR (1) | BRPI1011354A2 (ko) |
| CA (1) | CA2751525A1 (ko) |
| CO (1) | CO6400222A2 (ko) |
| EA (1) | EA201171010A1 (ko) |
| FR (1) | FR2941949B1 (ko) |
| IL (1) | IL214407A0 (ko) |
| MA (1) | MA33102B1 (ko) |
| MX (1) | MX2011008312A (ko) |
| SG (1) | SG173558A1 (ko) |
| TW (1) | TW201040187A (ko) |
| UY (1) | UY32419A (ko) |
| WO (1) | WO2010089506A1 (ko) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2848809A1 (en) | 2011-09-15 | 2013-03-21 | Novartis Ag | 6-substituted 3-(quinolin-6-ylthio)-[1,2,4]triazolo[4,3-a]pyradines as c-met tyrosine kinase |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1298125A1 (en) | 2001-09-26 | 2003-04-02 | Aventis Pharma S.A. | Substituted benzimidazole compounds and their use for the treatment of cancer |
| WO2007064797A2 (en) * | 2005-11-30 | 2007-06-07 | Vertex Pharmaceuticals Incorporated | Inhibitors of c-met and uses thereof |
| CN101360748B (zh) * | 2005-11-30 | 2012-05-30 | 沃泰克斯药物股份有限公司 | c-MET抑制剂及其应用 |
| PL1966214T3 (pl) * | 2005-12-21 | 2017-04-28 | Janssen Pharmaceutica N.V. | Triazolopirydazyny jako modulatory kinazy tyrozynowej |
| JP2009538899A (ja) * | 2006-05-30 | 2009-11-12 | ファイザー・プロダクツ・インク | トリアゾロピリダジン誘導体 |
| PE20121506A1 (es) * | 2006-07-14 | 2012-11-26 | Amgen Inc | Compuestos triazolopiridinas como inhibidores de c-met |
| BRPI0717320A2 (pt) * | 2006-10-23 | 2013-10-22 | Sgx Pharmaceuticals Inc | Triazóis bicíclicos como moduladores de proteína cinase |
| PA8792501A1 (es) * | 2007-08-09 | 2009-04-23 | Sanofi Aventis | Nuevos derivados de 6-triazolopiridacina-sulfanil benzotiazol y bencimidazol,su procedimiento de preparación,su aplicación como medicamentos,composiciones farmacéuticas y nueva utilización principalmente como inhibidores de met. |
-
2009
- 2009-02-06 FR FR0900510A patent/FR2941949B1/fr not_active Expired - Fee Related
-
2010
- 2010-02-04 CA CA2751525A patent/CA2751525A1/fr not_active Abandoned
- 2010-02-04 JP JP2011548750A patent/JP2012517407A/ja not_active Withdrawn
- 2010-02-04 MX MX2011008312A patent/MX2011008312A/es not_active Application Discontinuation
- 2010-02-04 SG SG2011056470A patent/SG173558A1/en unknown
- 2010-02-04 KR KR1020117020676A patent/KR20110126660A/ko not_active Application Discontinuation
- 2010-02-04 CN CN2010800150530A patent/CN102388029A/zh active Pending
- 2010-02-04 WO PCT/FR2010/050177 patent/WO2010089506A1/fr active Application Filing
- 2010-02-04 AU AU2010212231A patent/AU2010212231A1/en not_active Abandoned
- 2010-02-04 EP EP10708277A patent/EP2393790A1/fr not_active Withdrawn
- 2010-02-04 BR BRPI1011354A patent/BRPI1011354A2/pt not_active IP Right Cessation
- 2010-02-04 EA EA201171010A patent/EA201171010A1/ru unknown
- 2010-02-04 MA MA34147A patent/MA33102B1/fr unknown
- 2010-02-05 UY UY0001032419A patent/UY32419A/es not_active Application Discontinuation
- 2010-02-05 TW TW099103558A patent/TW201040187A/zh unknown
- 2010-02-05 AR ARP100100316A patent/AR075248A1/es unknown
-
2011
- 2011-08-02 IL IL214407A patent/IL214407A0/en unknown
- 2011-08-05 CO CO11099121A patent/CO6400222A2/es not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| EA201171010A1 (ru) | 2012-03-30 |
| BRPI1011354A2 (pt) | 2019-09-24 |
| WO2010089506A1 (fr) | 2010-08-12 |
| FR2941949B1 (fr) | 2011-04-01 |
| AU2010212231A1 (en) | 2011-08-25 |
| CA2751525A1 (fr) | 2010-08-12 |
| JP2012517407A (ja) | 2012-08-02 |
| MX2011008312A (es) | 2011-11-02 |
| CN102388029A (zh) | 2012-03-21 |
| MA33102B1 (fr) | 2012-03-01 |
| AR075248A1 (es) | 2011-03-16 |
| TW201040187A (en) | 2010-11-16 |
| IL214407A0 (en) | 2011-09-27 |
| FR2941949A1 (fr) | 2010-08-13 |
| CO6400222A2 (es) | 2012-03-15 |
| KR20110126660A (ko) | 2011-11-23 |
| EP2393790A1 (fr) | 2011-12-14 |
| UY32419A (es) | 2010-09-30 |
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