SG166799A1 - Quinoline derivatives as antibacterial agents - Google Patents

Quinoline derivatives as antibacterial agents

Info

Publication number
SG166799A1
SG166799A1 SG201007977-0A SG2010079770A SG166799A1 SG 166799 A1 SG166799 A1 SG 166799A1 SG 2010079770 A SG2010079770 A SG 2010079770A SG 166799 A1 SG166799 A1 SG 166799A1
Authority
SG
Singapore
Prior art keywords
antibacterial agents
compound
quinoline derivatives
bacterial infection
compounds
Prior art date
Application number
SG201007977-0A
Other languages
English (en)
Inventor
Koenraad Jozef Lodewijk Marcel Andries
Anil Koul
Jerome Emile Georges Guillemont
Magali Madeline Simone Motte
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of SG166799A1 publication Critical patent/SG166799A1/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20Oxygen atoms
    • C07D215/22Oxygen atoms attached in position 2 or 4
    • C07D215/227Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/36Sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Quinoline Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
SG201007977-0A 2005-06-28 2006-06-26 Quinoline derivatives as antibacterial agents SG166799A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP05105769 2005-06-28

Publications (1)

Publication Number Publication Date
SG166799A1 true SG166799A1 (en) 2010-12-29

Family

ID=35445742

Family Applications (1)

Application Number Title Priority Date Filing Date
SG201007977-0A SG166799A1 (en) 2005-06-28 2006-06-26 Quinoline derivatives as antibacterial agents

Country Status (34)

Country Link
US (2) US20100204270A1 (es)
EP (1) EP1898910B1 (es)
JP (1) JP5193859B2 (es)
KR (1) KR101423229B1 (es)
CN (1) CN101252928B (es)
AP (1) AP2733A (es)
AR (1) AR057654A1 (es)
AU (1) AU2006263884B2 (es)
BR (1) BRPI0612534B8 (es)
CA (1) CA2612623C (es)
CY (1) CY1118515T1 (es)
DK (1) DK1898910T3 (es)
EA (1) EA014163B1 (es)
ES (1) ES2606772T3 (es)
HK (1) HK1120734A1 (es)
HR (1) HRP20161704T1 (es)
HU (1) HUE031268T2 (es)
IL (1) IL188394A (es)
JO (1) JO3270B1 (es)
LT (1) LT1898910T (es)
ME (1) ME02690B (es)
MX (1) MX2008000082A (es)
MY (1) MY151030A (es)
NO (1) NO341283B1 (es)
NZ (1) NZ564339A (es)
PL (1) PL1898910T3 (es)
PT (1) PT1898910T (es)
RS (1) RS55408B1 (es)
SG (1) SG166799A1 (es)
SI (1) SI1898910T1 (es)
TW (1) TWI392494B (es)
UA (1) UA91549C2 (es)
WO (1) WO2007000436A1 (es)
ZA (1) ZA200711149B (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9790186B2 (en) 2009-07-21 2017-10-17 Trustees Of Dartmouth College Composition and method for prevention, mitigation or treatment of an enteropathogenic bacterial infection
US9617244B2 (en) 2012-04-27 2017-04-11 Janssen Pharmaceutica Nv Antibacterial quinoline derivatives
AU2013254674B2 (en) 2012-04-27 2017-02-02 Janssen Pharmaceutica Nv Antibacterial quinoline derivatives
CN105037497B (zh) * 2015-03-27 2018-06-26 中牧实业股份有限公司 一种恩拉霉素的提纯方法
WO2017035288A1 (en) * 2015-08-27 2017-03-02 Trustees Of Dartmouth College Composition and method for prevention, mitigation or treatment of an enteropathogenic bacterial infection

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6103905A (en) * 1997-06-19 2000-08-15 Sepracor, Inc. Quinoline-indole antimicrobial agents, uses and compositions related thereto
DE19937116A1 (de) * 1999-08-06 2001-02-08 Bayer Ag Moxifloxacin Kochsalzformulierung
NZ538391A (en) * 2002-07-25 2005-10-28 Janssen Pharmaceutica Nv Quinoline derivatives and their use as mycobacterial inhibitors
BRPI0510414B1 (pt) * 2004-05-28 2022-04-05 Janssen Pharmaceutica N.V. Combinação e composição farmacêutica
EE05394B1 (et) * 2004-12-24 2011-04-15 Janssen Pharmaceutica N.V. Kinoliinihendid kasutamiseks latentse tuberkuloosi ravis

Also Published As

Publication number Publication date
JP2008546825A (ja) 2008-12-25
CN101252928A (zh) 2008-08-27
SI1898910T1 (sl) 2017-01-31
PT1898910T (pt) 2016-11-16
BRPI0612534A8 (pt) 2017-12-26
HUE031268T2 (en) 2017-06-28
EP1898910B1 (en) 2016-09-28
BRPI0612534B1 (pt) 2020-04-22
BRPI0612534A2 (pt) 2010-11-23
CN101252928B (zh) 2012-05-23
AR057654A1 (es) 2007-12-12
RS55408B1 (sr) 2017-04-28
NZ564339A (en) 2011-02-25
EP1898910A1 (en) 2008-03-19
IL188394A (en) 2012-09-24
WO2007000436A1 (en) 2007-01-04
HK1120734A1 (en) 2009-04-09
TW200738237A (en) 2007-10-16
JP5193859B2 (ja) 2013-05-08
KR101423229B1 (ko) 2014-07-25
KR20080028460A (ko) 2008-03-31
LT1898910T (lt) 2017-01-10
US20130030017A1 (en) 2013-01-31
ZA200711149B (en) 2009-06-24
AU2006263884B2 (en) 2013-01-10
HRP20161704T1 (hr) 2017-02-10
IL188394A0 (en) 2008-08-07
MY151030A (en) 2014-03-31
EA014163B1 (ru) 2010-10-29
EA200800152A1 (ru) 2008-06-30
BRPI0612534B8 (pt) 2021-05-25
ME02690B (me) 2017-10-20
NO341283B1 (no) 2017-10-02
CY1118515T1 (el) 2017-07-12
US20100204270A1 (en) 2010-08-12
PL1898910T3 (pl) 2017-03-31
JO3270B1 (ar) 2018-09-16
CA2612623C (en) 2016-09-27
NO20080481L (no) 2008-02-29
UA91549C2 (ru) 2010-08-10
TWI392494B (zh) 2013-04-11
AU2006263884A1 (en) 2007-01-04
AP2733A (en) 2013-09-30
ES2606772T3 (es) 2017-03-27
CA2612623A1 (en) 2007-01-04
DK1898910T3 (en) 2017-01-09
MX2008000082A (es) 2008-03-24

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