SG165339A1 - Incorporation of non-naturally encoded amino acids into proteins - Google Patents
Incorporation of non-naturally encoded amino acids into proteinsInfo
- Publication number
- SG165339A1 SG165339A1 SG201006401-2A SG2010064012A SG165339A1 SG 165339 A1 SG165339 A1 SG 165339A1 SG 2010064012 A SG2010064012 A SG 2010064012A SG 165339 A1 SG165339 A1 SG 165339A1
- Authority
- SG
- Singapore
- Prior art keywords
- amino acids
- encoded amino
- naturally encoded
- incorporation
- proteins
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/10—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
- C07H21/04—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
- C12N15/78—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Pseudomonas
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Endocrinology (AREA)
- Diabetes (AREA)
- Veterinary Medicine (AREA)
- Gastroenterology & Hepatology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US68760305P | 2005-06-03 | 2005-06-03 |
Publications (1)
Publication Number | Publication Date |
---|---|
SG165339A1 true SG165339A1 (en) | 2010-10-28 |
Family
ID=37498945
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG201006401-2A SG165339A1 (en) | 2005-06-03 | 2006-06-02 | Incorporation of non-naturally encoded amino acids into proteins |
Country Status (11)
Country | Link |
---|---|
US (1) | US20080227205A1 (de) |
EP (1) | EP1891092A4 (de) |
JP (1) | JP2008541766A (de) |
KR (1) | KR20080026120A (de) |
CN (1) | CN101238143A (de) |
AU (1) | AU2006255280A1 (de) |
CA (1) | CA2608192A1 (de) |
IL (1) | IL187191A0 (de) |
MX (1) | MX2007015106A (de) |
SG (1) | SG165339A1 (de) |
WO (1) | WO2006132969A2 (de) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20050287639A1 (en) | 2004-05-17 | 2005-12-29 | California Institute Of Technology | Methods of incorporating amino acid analogs into proteins |
AU2006332809A1 (en) * | 2005-12-30 | 2007-07-12 | Ambrx, Inc. | Compositions containing, methods involving, and uses of non-natural amino acids and polypeptides |
US8518666B2 (en) | 2006-03-03 | 2013-08-27 | California Institute Of Technology | Site-specific incorporation of amino acids into molecules |
BRPI0809583B1 (pt) * | 2007-03-30 | 2022-02-22 | Ambrx, Inc | Polipeptídeo fgf-21 modificado, composição compreendendo o mesmo, método para produzir o referido polipetídeo fgf-21 e célula compreendendo um polinucleotídeo |
NZ603812A (en) | 2007-11-20 | 2014-06-27 | Ambrx Inc | Modified insulin polypeptides and their uses |
WO2009075788A1 (en) * | 2007-12-05 | 2009-06-18 | Semprus Biociences Corporation | Synthetic non-fouling amino acids |
US9238878B2 (en) | 2009-02-17 | 2016-01-19 | Redwood Bioscience, Inc. | Aldehyde-tagged protein-based drug carriers and methods of use |
EP2427204B1 (de) | 2009-05-06 | 2017-04-05 | Janssen Biotech, Inc. | Melanocortinrezeptor-bindende konjugate |
WO2011079293A1 (en) * | 2009-12-23 | 2011-06-30 | Ambrx, Inc | Tumor necrosis factor-related apoptosis inducing ligand polypeptides and their uses |
CN103044539B (zh) * | 2010-04-09 | 2014-10-22 | 苏州元基生物技术有限公司 | 重组促红细胞生成素及制备方法 |
US9567386B2 (en) | 2010-08-17 | 2017-02-14 | Ambrx, Inc. | Therapeutic uses of modified relaxin polypeptides |
MY162837A (en) | 2010-08-17 | 2017-07-31 | Ambrx Inc | Modified relaxin polypeptides and their uses |
CN103415621A (zh) | 2011-01-14 | 2013-11-27 | 雷德伍德生物科技股份有限公司 | 醛标记免疫球蛋白多肽及其使用方法 |
CA2862292C (en) | 2012-01-20 | 2019-10-08 | Sea Lane Biotechnologies, Llc | Binding molecule conjugates |
CN105420203B (zh) * | 2014-09-03 | 2018-11-16 | 中国科学院生物物理研究所 | 酪氨酸类似物翻译系统和基因编码的蛋白质光致电子转移荧光传感器蛋白家族 |
UY36370A (es) * | 2014-10-24 | 2016-04-29 | Bristol Myers Squibb Company Una Corporación Del Estado De Delaware | Polipéptidos fgf-21 modificados y sus usos |
JP2019515677A (ja) | 2016-04-26 | 2019-06-13 | アール.ピー.シェーラー テクノロジーズ エルエルシー | 抗体複合体ならびにそれを作製および使用する方法 |
WO2017196954A1 (en) * | 2016-05-10 | 2017-11-16 | Sony Corporation | Ultra bright polymeric dyes with peptide backbones |
ES2963839T3 (es) | 2017-02-08 | 2024-04-02 | Bristol Myers Squibb Co | Polipéptidos de relaxina modificados que comprenden un potenciador farmacocinético y usos de los mismos |
EP3381932A1 (de) * | 2017-03-28 | 2018-10-03 | Technische Universität Berlin | Modifizierte muschelproteine, verwendungen davon und zugehörige verbindungen |
CN112375774A (zh) * | 2020-10-26 | 2021-02-19 | 浙江新码生物医药有限公司 | 一种重组蛋白表达用工程菌株的构建方法 |
CN112279906B (zh) * | 2020-10-30 | 2022-09-20 | 浙江新码生物医药有限公司 | 人白细胞介素2-聚乙二醇偶联物及其制备方法与应用 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6586207B2 (en) * | 2000-05-26 | 2003-07-01 | California Institute Of Technology | Overexpression of aminoacyl-tRNA synthetases for efficient production of engineered proteins containing amino acid analogues |
DK2128246T3 (da) * | 2001-04-19 | 2014-05-12 | Univ California | Fremgangsmåder og sammensætninger til fremstilling af ortogonale tRNA-aminoacyl-tRNA-syntetasepar. |
JP2007519422A (ja) * | 2004-02-02 | 2007-07-19 | アンブレツクス・インコーポレイテツド | 修飾されたヒト四螺旋バンドルポリペプチド及びそれらの使用 |
ATE541934T1 (de) * | 2004-12-22 | 2012-02-15 | Ambrx Inc | Zusammensetzungen von aminoacyl-trna-synthetase und verwendungen davon |
-
2006
- 2006-06-02 JP JP2008514900A patent/JP2008541766A/ja active Pending
- 2006-06-02 SG SG201006401-2A patent/SG165339A1/en unknown
- 2006-06-02 WO PCT/US2006/021463 patent/WO2006132969A2/en active Application Filing
- 2006-06-02 AU AU2006255280A patent/AU2006255280A1/en not_active Abandoned
- 2006-06-02 MX MX2007015106A patent/MX2007015106A/es unknown
- 2006-06-02 EP EP06771955A patent/EP1891092A4/de not_active Withdrawn
- 2006-06-02 CN CNA2006800195802A patent/CN101238143A/zh active Pending
- 2006-06-02 US US11/915,843 patent/US20080227205A1/en not_active Abandoned
- 2006-06-02 KR KR1020077030326A patent/KR20080026120A/ko not_active Application Discontinuation
- 2006-06-02 CA CA002608192A patent/CA2608192A1/en not_active Abandoned
-
2007
- 2007-11-06 IL IL187191A patent/IL187191A0/en unknown
Also Published As
Publication number | Publication date |
---|---|
EP1891092A4 (de) | 2011-12-21 |
CN101238143A (zh) | 2008-08-06 |
CA2608192A1 (en) | 2006-12-14 |
US20080227205A1 (en) | 2008-09-18 |
WO2006132969A2 (en) | 2006-12-14 |
AU2006255280A1 (en) | 2006-12-14 |
KR20080026120A (ko) | 2008-03-24 |
WO2006132969A3 (en) | 2007-11-22 |
IL187191A0 (en) | 2008-02-09 |
JP2008541766A (ja) | 2008-11-27 |
EP1891092A2 (de) | 2008-02-27 |
MX2007015106A (es) | 2008-02-15 |
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