SG144944A1 - Stable modifications of tegaserod hydrogen maleate - Google Patents
Stable modifications of tegaserod hydrogen maleateInfo
- Publication number
- SG144944A1 SG144944A1 SG200805476-9A SG2008054769A SG144944A1 SG 144944 A1 SG144944 A1 SG 144944A1 SG 2008054769 A SG2008054769 A SG 2008054769A SG 144944 A1 SG144944 A1 SG 144944A1
- Authority
- SG
- Singapore
- Prior art keywords
- hydrogen maleate
- stable modifications
- tegaserod hydrogen
- tegaserod
- stable
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
- A61K31/4045—Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/10—Laxatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines Containing Plant Substances (AREA)
- Plural Heterocyclic Compounds (AREA)
- Glass Compositions (AREA)
- Liquid Crystal Substances (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US48963803P | 2003-07-24 | 2003-07-24 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG144944A1 true SG144944A1 (en) | 2008-08-28 |
Family
ID=34135099
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG200805476-9A SG144944A1 (en) | 2003-07-24 | 2004-07-23 | Stable modifications of tegaserod hydrogen maleate |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US20070112056A1 (ru) |
| EP (2) | EP1651601A1 (ru) |
| JP (1) | JP2006528609A (ru) |
| KR (1) | KR20060040710A (ru) |
| CN (1) | CN1826318A (ru) |
| AR (1) | AR045081A1 (ru) |
| AU (1) | AU2004263285A1 (ru) |
| BR (1) | BRPI0412830A (ru) |
| CA (1) | CA2532351A1 (ru) |
| CO (1) | CO5680418A2 (ru) |
| EC (1) | ECSP066306A (ru) |
| IL (1) | IL172914A0 (ru) |
| IS (1) | IS8321A (ru) |
| MA (1) | MA27935A1 (ru) |
| MX (1) | MXPA06000917A (ru) |
| MY (1) | MY137386A (ru) |
| NO (1) | NO20060915L (ru) |
| NZ (1) | NZ544596A (ru) |
| PE (1) | PE20050253A1 (ru) |
| RU (1) | RU2349585C2 (ru) |
| SG (1) | SG144944A1 (ru) |
| TN (1) | TNSN06024A1 (ru) |
| TW (1) | TW200510302A (ru) |
| WO (1) | WO2005014544A1 (ru) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006045120A2 (en) * | 2004-10-19 | 2006-04-27 | Teva Pharmaceutical Industries Ltd. | Purification of tegaserod maleate |
| BRPI0606898A2 (pt) * | 2005-01-31 | 2009-07-21 | Novartis Ag | uso de agonista de 5-ht4 na preparação de medicamentos e método útil no esvaziamento gástrico retardado |
| CZ298399B6 (cs) * | 2005-05-02 | 2007-09-19 | Zentiva, A. S. | Zpusob prípravy 2-[(5-methoxy-1 H-indol-3-yl) methylen]-N-pentylkarbazimidamidu (tegaserodu) |
| EP1893195A2 (en) * | 2005-06-22 | 2008-03-05 | Teva Pharmaceutical Industries Ltd | Polymorphic forms of tegaserod maleate |
| WO2007119109A2 (en) * | 2005-10-06 | 2007-10-25 | Medichem, S.A. | Processes for preparing tegaserod maleate and pharmaceutical compositions containing it |
| GB0524668D0 (en) * | 2005-12-02 | 2006-01-11 | Novartis Ag | Organic compounds |
| WO2007120924A1 (en) * | 2006-04-17 | 2007-10-25 | Teva Pharmaceutical Industries Ltd. | Preparation of tegaserod maleate free of iodide |
| EP1956002A1 (en) * | 2007-02-07 | 2008-08-13 | Chemo Ibérica, S.A. | New tegaserod maleate polymorphs and process for their preparation |
| AU2008252604A1 (en) * | 2007-05-17 | 2008-11-27 | Generics [Uk] Limited | Process for the preparation of form A of tegaserod |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH01242588A (ja) * | 1988-03-25 | 1989-09-27 | Chiba Gosei Kenkyusho:Kk | ７―シアノメチルチオアセトアミド―７α―メトキシ―３―（１―メチル―１Ｈ―テトラゾール―５―イル）チオメチル―３―セフェム―４―カルボン酸の結晶及びその製造方法 |
| HUT64023A (en) * | 1991-03-22 | 1993-11-29 | Sandoz Ag | Process for producing aminoguanidine derivatives and pharmaceutical compositions comprising such compounds |
| JPH08291140A (ja) * | 1995-04-20 | 1996-11-05 | Teikoku Chem Ind Corp Ltd | 易吸収性結晶 |
| CN1165293C (zh) * | 1998-08-21 | 2004-09-08 | 诺瓦提斯公司 | 5ht4激动剂或拮抗剂的新型口服制剂 |
| EP1321142A1 (en) * | 2001-12-21 | 2003-06-25 | Novartis AG | Solid pharmaceutical composition for oral administration of Tegaserod |
| CN1176077C (zh) * | 2003-01-07 | 2004-11-17 | 江苏省药物研究所 | 马来酸替加色罗一水结晶 |
| US20050119328A1 (en) * | 2003-03-25 | 2005-06-02 | Hetero Drugs Limited | Novel crysalline forms of tegaserod maleate |
| JP2007514000A (ja) * | 2003-12-16 | 2007-05-31 | テバ ファーマシューティカル インダストリーズ リミティド | テガセロッド塩基及びその塩の多形現象形 |
| US20050272802A1 (en) * | 2004-04-22 | 2005-12-08 | Sundaram Venkataraman | Process for preparing form I of tegaserod maleate |
| EP1893195A2 (en) * | 2005-06-22 | 2008-03-05 | Teva Pharmaceutical Industries Ltd | Polymorphic forms of tegaserod maleate |
-
2004
- 2004-07-22 AR ARP040102610A patent/AR045081A1/es not_active Application Discontinuation
- 2004-07-22 TW TW093121920A patent/TW200510302A/zh unknown
- 2004-07-22 MY MYPI20042945A patent/MY137386A/en unknown
- 2004-07-22 PE PE2004000706A patent/PE20050253A1/es not_active Application Discontinuation
- 2004-07-23 CN CNA2004800213549A patent/CN1826318A/zh active Pending
- 2004-07-23 JP JP2006520806A patent/JP2006528609A/ja active Pending
- 2004-07-23 RU RU2006105481/04A patent/RU2349585C2/ru not_active IP Right Cessation
- 2004-07-23 SG SG200805476-9A patent/SG144944A1/en unknown
- 2004-07-23 BR BRPI0412830-3A patent/BRPI0412830A/pt not_active IP Right Cessation
- 2004-07-23 NZ NZ544596A patent/NZ544596A/en unknown
- 2004-07-23 US US10/565,454 patent/US20070112056A1/en not_active Abandoned
- 2004-07-23 EP EP04763452A patent/EP1651601A1/en not_active Withdrawn
- 2004-07-23 EP EP07117155A patent/EP1880992A1/en not_active Withdrawn
- 2004-07-23 KR KR1020067001500A patent/KR20060040710A/ko not_active Application Discontinuation
- 2004-07-23 AU AU2004263285A patent/AU2004263285A1/en not_active Abandoned
- 2004-07-23 WO PCT/EP2004/008281 patent/WO2005014544A1/en not_active Application Discontinuation
- 2004-07-23 CA CA002532351A patent/CA2532351A1/en not_active Abandoned
- 2004-07-23 MX MXPA06000917A patent/MXPA06000917A/es unknown
-
2005
- 2005-12-29 IL IL172914A patent/IL172914A0/en unknown
-
2006
- 2006-01-23 TN TNP2006000024A patent/TNSN06024A1/en unknown
- 2006-01-24 EC EC2006006306A patent/ECSP066306A/es unknown
- 2006-01-27 MA MA28759A patent/MA27935A1/fr unknown
- 2006-02-21 CO CO06016978A patent/CO5680418A2/es not_active Application Discontinuation
- 2006-02-22 IS IS8321A patent/IS8321A/is unknown
- 2006-02-24 NO NO20060915A patent/NO20060915L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| US20070112056A1 (en) | 2007-05-17 |
| IL172914A0 (en) | 2006-06-11 |
| EP1880992A1 (en) | 2008-01-23 |
| AU2004263285A1 (en) | 2005-02-17 |
| MXPA06000917A (es) | 2006-03-30 |
| AR045081A1 (es) | 2005-10-12 |
| WO2005014544A1 (en) | 2005-02-17 |
| PE20050253A1 (es) | 2005-06-03 |
| NO20060915L (no) | 2006-04-24 |
| CA2532351A1 (en) | 2005-02-17 |
| KR20060040710A (ko) | 2006-05-10 |
| MY137386A (en) | 2009-01-30 |
| CO5680418A2 (es) | 2006-09-29 |
| ECSP066306A (es) | 2006-07-28 |
| JP2006528609A (ja) | 2006-12-21 |
| TW200510302A (en) | 2005-03-16 |
| BRPI0412830A (pt) | 2006-09-26 |
| MA27935A1 (fr) | 2006-06-01 |
| NZ544596A (en) | 2009-01-31 |
| IS8321A (is) | 2006-02-22 |
| TNSN06024A1 (en) | 2007-10-03 |
| RU2006105481A (ru) | 2007-09-20 |
| RU2349585C2 (ru) | 2009-03-20 |
| CN1826318A (zh) | 2006-08-30 |
| EP1651601A1 (en) | 2006-05-03 |
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