MA27935A1 - Modifications stables du maleate d'hydrogene tegaserod - Google Patents
Modifications stables du maleate d'hydrogene tegaserodInfo
- Publication number
- MA27935A1 MA27935A1 MA28759A MA28759A MA27935A1 MA 27935 A1 MA27935 A1 MA 27935A1 MA 28759 A MA28759 A MA 28759A MA 28759 A MA28759 A MA 28759A MA 27935 A1 MA27935 A1 MA 27935A1
- Authority
- MA
- Morocco
- Prior art keywords
- hydrogen maleate
- tegaserod hydrogen
- stable modifications
- tegaserod
- stable
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
- A61K31/4045—Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/10—Laxatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines Containing Plant Substances (AREA)
- Plural Heterocyclic Compounds (AREA)
- Glass Compositions (AREA)
- Liquid Crystal Substances (AREA)
- Indole Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Cette invention se rapporte à des formes cristallines du maléate d'hydrogène tegaserod, à leur utilisation dans des compositions pharmaceutiques servant au traitement du syndrome du côlon irritable, du reflux gastrooesophagien pathologique, de la dyspepsie fonctionnelle, et de la constipation ou de la diarrhée chroniques, ainsi qu'à leur production.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US48963803P | 2003-07-24 | 2003-07-24 |
Publications (1)
Publication Number | Publication Date |
---|---|
MA27935A1 true MA27935A1 (fr) | 2006-06-01 |
Family
ID=34135099
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA28759A MA27935A1 (fr) | 2003-07-24 | 2006-01-27 | Modifications stables du maleate d'hydrogene tegaserod |
Country Status (24)
Country | Link |
---|---|
US (1) | US20070112056A1 (fr) |
EP (2) | EP1651601A1 (fr) |
JP (1) | JP2006528609A (fr) |
KR (1) | KR20060040710A (fr) |
CN (1) | CN1826318A (fr) |
AR (1) | AR045081A1 (fr) |
AU (1) | AU2004263285A1 (fr) |
BR (1) | BRPI0412830A (fr) |
CA (1) | CA2532351A1 (fr) |
CO (1) | CO5680418A2 (fr) |
EC (1) | ECSP066306A (fr) |
IL (1) | IL172914A0 (fr) |
IS (1) | IS8321A (fr) |
MA (1) | MA27935A1 (fr) |
MX (1) | MXPA06000917A (fr) |
MY (1) | MY137386A (fr) |
NO (1) | NO20060915L (fr) |
NZ (1) | NZ544596A (fr) |
PE (1) | PE20050253A1 (fr) |
RU (1) | RU2349585C2 (fr) |
SG (1) | SG144944A1 (fr) |
TN (1) | TNSN06024A1 (fr) |
TW (1) | TW200510302A (fr) |
WO (1) | WO2005014544A1 (fr) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2007514777A (ja) * | 2004-10-19 | 2007-06-07 | テバ ファーマシューティカル インダストリーズ リミティド | テガセロッドマレエートの精製 |
JP2008528615A (ja) * | 2005-01-31 | 2008-07-31 | ノバルティス アクチエンゲゼルシャフト | プロトンポンプ阻害剤により誘発され得る遅延した胃内容排出の処置のための5−ht4アゴニストの使用 |
CZ298399B6 (cs) * | 2005-05-02 | 2007-09-19 | Zentiva, A. S. | Zpusob prípravy 2-[(5-methoxy-1 H-indol-3-yl) methylen]-N-pentylkarbazimidamidu (tegaserodu) |
KR20070062504A (ko) * | 2005-06-22 | 2007-06-15 | 테바 파마슈티컬 인더스트리즈 리미티드 | 테가세로드 말레이트의 다형태 |
WO2007119109A2 (fr) * | 2005-10-06 | 2007-10-25 | Medichem, S.A. | Compositions et procédés utiles pour la préparation de maléate de tégaserod |
GB0524668D0 (en) * | 2005-12-02 | 2006-01-11 | Novartis Ag | Organic compounds |
WO2007120924A1 (fr) * | 2006-04-17 | 2007-10-25 | Teva Pharmaceutical Industries Ltd. | Préparation de maléate de tegaserod exempt de iodure |
EP1956002A1 (fr) * | 2007-02-07 | 2008-08-13 | Chemo Ibérica, S.A. | Nouveaux polymorphes de maléate de tégasérod et leur procédé de préparation |
WO2008142445A1 (fr) * | 2007-05-17 | 2008-11-27 | Generics [Uk] Limited | Procédé de préparation de la forme a du tégasérode |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH01242588A (ja) * | 1988-03-25 | 1989-09-27 | Chiba Gosei Kenkyusho:Kk | 7―シアノメチルチオアセトアミド―7α―メトキシ―3―(1―メチル―1H―テトラゾール―5―イル)チオメチル―3―セフェム―4―カルボン酸の結晶及びその製造方法 |
HUT64023A (en) * | 1991-03-22 | 1993-11-29 | Sandoz Ag | Process for producing aminoguanidine derivatives and pharmaceutical compositions comprising such compounds |
JPH08291140A (ja) * | 1995-04-20 | 1996-11-05 | Teikoku Chem Ind Corp Ltd | 易吸収性結晶 |
NZ509832A (en) * | 1998-08-21 | 2003-11-28 | Novartis Ag | New oral formulation for 5-HT4 agonists or antagonists |
EP1321142A1 (fr) * | 2001-12-21 | 2003-06-25 | Novartis AG | Forme solide pour l'administration orale du Tégaserode |
CN1176077C (zh) * | 2003-01-07 | 2004-11-17 | 江苏省药物研究所 | 马来酸替加色罗一水结晶 |
WO2004085393A1 (fr) * | 2003-03-25 | 2004-10-07 | Hetero Drugs Limited | Nouvelles formes cristallines de maleate de tegaserod |
CA2550886A1 (fr) * | 2003-12-16 | 2005-06-30 | Teva Pharmaceutical Industries Ltd. | Formes polymorphiques de la base du tegaserod et des sels de celui-ci |
US20050272802A1 (en) * | 2004-04-22 | 2005-12-08 | Sundaram Venkataraman | Process for preparing form I of tegaserod maleate |
KR20070062504A (ko) * | 2005-06-22 | 2007-06-15 | 테바 파마슈티컬 인더스트리즈 리미티드 | 테가세로드 말레이트의 다형태 |
-
2004
- 2004-07-22 AR ARP040102610A patent/AR045081A1/es not_active Application Discontinuation
- 2004-07-22 PE PE2004000706A patent/PE20050253A1/es not_active Application Discontinuation
- 2004-07-22 TW TW093121920A patent/TW200510302A/zh unknown
- 2004-07-22 MY MYPI20042945A patent/MY137386A/en unknown
- 2004-07-23 MX MXPA06000917A patent/MXPA06000917A/es unknown
- 2004-07-23 EP EP04763452A patent/EP1651601A1/fr not_active Withdrawn
- 2004-07-23 BR BRPI0412830-3A patent/BRPI0412830A/pt not_active IP Right Cessation
- 2004-07-23 SG SG200805476-9A patent/SG144944A1/en unknown
- 2004-07-23 WO PCT/EP2004/008281 patent/WO2005014544A1/fr not_active Application Discontinuation
- 2004-07-23 JP JP2006520806A patent/JP2006528609A/ja active Pending
- 2004-07-23 EP EP07117155A patent/EP1880992A1/fr not_active Withdrawn
- 2004-07-23 US US10/565,454 patent/US20070112056A1/en not_active Abandoned
- 2004-07-23 AU AU2004263285A patent/AU2004263285A1/en not_active Abandoned
- 2004-07-23 CN CNA2004800213549A patent/CN1826318A/zh active Pending
- 2004-07-23 RU RU2006105481/04A patent/RU2349585C2/ru not_active IP Right Cessation
- 2004-07-23 CA CA002532351A patent/CA2532351A1/fr not_active Abandoned
- 2004-07-23 KR KR1020067001500A patent/KR20060040710A/ko not_active Application Discontinuation
- 2004-07-23 NZ NZ544596A patent/NZ544596A/en unknown
-
2005
- 2005-12-29 IL IL172914A patent/IL172914A0/en unknown
-
2006
- 2006-01-23 TN TNP2006000024A patent/TNSN06024A1/en unknown
- 2006-01-24 EC EC2006006306A patent/ECSP066306A/es unknown
- 2006-01-27 MA MA28759A patent/MA27935A1/fr unknown
- 2006-02-21 CO CO06016978A patent/CO5680418A2/es not_active Application Discontinuation
- 2006-02-22 IS IS8321A patent/IS8321A/is unknown
- 2006-02-24 NO NO20060915A patent/NO20060915L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
MY137386A (en) | 2009-01-30 |
RU2349585C2 (ru) | 2009-03-20 |
SG144944A1 (en) | 2008-08-28 |
RU2006105481A (ru) | 2007-09-20 |
BRPI0412830A (pt) | 2006-09-26 |
AU2004263285A1 (en) | 2005-02-17 |
CA2532351A1 (fr) | 2005-02-17 |
TNSN06024A1 (en) | 2007-10-03 |
AR045081A1 (es) | 2005-10-12 |
ECSP066306A (es) | 2006-07-28 |
TW200510302A (en) | 2005-03-16 |
IL172914A0 (en) | 2006-06-11 |
KR20060040710A (ko) | 2006-05-10 |
JP2006528609A (ja) | 2006-12-21 |
EP1880992A1 (fr) | 2008-01-23 |
MXPA06000917A (es) | 2006-03-30 |
IS8321A (is) | 2006-02-22 |
NO20060915L (no) | 2006-04-24 |
US20070112056A1 (en) | 2007-05-17 |
EP1651601A1 (fr) | 2006-05-03 |
NZ544596A (en) | 2009-01-31 |
WO2005014544A1 (fr) | 2005-02-17 |
CN1826318A (zh) | 2006-08-30 |
PE20050253A1 (es) | 2005-06-03 |
CO5680418A2 (es) | 2006-09-29 |
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