SG131015A1 - Method and apparatus for making porous agarose beads - Google Patents

Method and apparatus for making porous agarose beads

Info

Publication number
SG131015A1
SG131015A1 SG200605757-4A SG2006057574A SG131015A1 SG 131015 A1 SG131015 A1 SG 131015A1 SG 2006057574 A SG2006057574 A SG 2006057574A SG 131015 A1 SG131015 A1 SG 131015A1
Authority
SG
Singapore
Prior art keywords
agarose
beads
cored
droplets
hydrophobic liquid
Prior art date
Application number
SG200605757-4A
Other languages
English (en)
Inventor
Kwok-Shun Cheng
Senthilkumar Ramaswamy
Nanying Bian
Brian Gagnon
Joaquin Umana
Neil P Soice
Original Assignee
Millipore Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Millipore Corp filed Critical Millipore Corp
Publication of SG131015A1 publication Critical patent/SG131015A1/en

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/22—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising organic material
    • B01J20/24—Naturally occurring macromolecular compounds, e.g. humic acids or their derivatives
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • B01J13/04—Making microcapsules or microballoons by physical processes, e.g. drying, spraying
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/28—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
    • B01J20/28002—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their physical properties
    • B01J20/28009—Magnetic properties
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/282—Porous sorbents
    • B01J20/285—Porous sorbents based on polymers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/286—Phases chemically bonded to a substrate, e.g. to silica or to polymers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/291—Gel sorbents
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3202—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the carrier, support or substrate used for impregnation or coating
    • B01J20/3204—Inorganic carriers, supports or substrates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B01J20/3244—Non-macromolecular compounds
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B01J20/3268—Macromolecular compounds
    • B01J20/3272—Polymers obtained by reactions otherwise than involving only carbon to carbon unsaturated bonds
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B01J20/3268—Macromolecular compounds
    • B01J20/328—Polymers on the carrier being further modified
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B01J20/3268—Macromolecular compounds
    • B01J20/328—Polymers on the carrier being further modified
    • B01J20/3282—Crosslinked polymers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3289—Coatings involving more than one layer of same or different nature
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3291—Characterised by the shape of the carrier, the coating or the obtained coated product
    • B01J20/3293—Coatings on a core, the core being particle or fiber shaped, e.g. encapsulated particles, coated fibers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2220/00—Aspects relating to sorbent materials
    • B01J2220/40—Aspects relating to the composition of sorbent or filter aid materials
    • B01J2220/48—Sorbents characterised by the starting material used for their preparation
    • B01J2220/4812—Sorbents characterised by the starting material used for their preparation the starting material being of organic character
    • B01J2220/4825—Polysaccharides or cellulose materials, e.g. starch, chitin, sawdust, wood, straw, cotton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Colloid Chemistry (AREA)
  • Manufacture Of Porous Articles, And Recovery And Treatment Of Waste Products (AREA)
SG200605757-4A 2005-09-15 2006-08-23 Method and apparatus for making porous agarose beads SG131015A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US71737105P 2005-09-15 2005-09-15

Publications (1)

Publication Number Publication Date
SG131015A1 true SG131015A1 (en) 2007-04-26

Family

ID=37496434

Family Applications (1)

Application Number Title Priority Date Filing Date
SG200605757-4A SG131015A1 (en) 2005-09-15 2006-08-23 Method and apparatus for making porous agarose beads

Country Status (8)

Country Link
US (2) US7678302B2 (zh)
EP (1) EP1764151B1 (zh)
JP (1) JP4662900B2 (zh)
CN (1) CN1939582B (zh)
DK (1) DK1764151T3 (zh)
ES (1) ES2582362T3 (zh)
PL (1) PL1764151T3 (zh)
SG (1) SG131015A1 (zh)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG131015A1 (en) * 2005-09-15 2007-04-26 Millipore Corp Method and apparatus for making porous agarose beads
SG131016A1 (en) * 2005-09-19 2007-04-26 Millipore Corp Asymmetric porous adsorptive bead
CA2655873C (en) * 2006-07-14 2017-10-17 Wisconsin Alumni Research Foundation Adsorptive membranes for trapping viruses
CN101293191B (zh) * 2007-04-25 2011-11-09 中国科学院过程工程研究所 一种琼脂糖凝胶微球的制备方法
BRPI0820008B1 (pt) 2007-12-03 2017-05-30 Dpx Holdings Bv sistema e método para produção de microesferas
EP2398577A2 (en) * 2009-02-19 2011-12-28 Bonner, Alex Garfield Porous interpenetrating polymer network
DE102009011521A1 (de) * 2009-03-06 2010-09-16 Wolfgang Folger Vorrichtung und Verfahren zur Herstellung von Eisperlen aus einem wässrigen Gemisch
DE102010040687A1 (de) * 2010-09-14 2012-03-15 Hamilton Bonaduz Ag Verfahren zum Herstellen von Wirkstoff-Beads
DE102010040685A1 (de) * 2010-09-14 2012-03-15 Hamilton Bonaduz Ag Temperiervorrichtung zur thermischen Verfestigung von Wirkstoff-Beads
GB201113775D0 (en) 2011-08-10 2011-09-21 British American Tobacco Co Capsule formation
GB201113776D0 (en) 2011-08-10 2011-09-21 British American Tobacco Co Capsule formation
PL2809782T3 (pl) 2012-01-31 2018-04-30 The Rogosin Institute, Inc. Ulepszony sposób wytwarzania makroperełek
WO2016117574A1 (ja) * 2015-01-19 2016-07-28 日立化成株式会社 分離材
JP6852259B2 (ja) * 2016-01-07 2021-03-31 昭和電工マテリアルズ株式会社 分離材及びカラム
JP6746919B2 (ja) * 2016-01-15 2020-08-26 日立化成株式会社 分離材及びカラム
US11549097B2 (en) 2016-03-01 2023-01-10 Oxford University Innovation Limited Phase transfer of a cargo laden scaffold
GB201615066D0 (en) * 2016-09-06 2016-10-19 Ge Healthcare Bioprocess R&D Ab Packed bed emulsification
US10526710B2 (en) 2016-12-16 2020-01-07 Purolite (China) Co., Ltd. Method of producing uniform polymer beads by vibration jetting with superhydrophobic membrane
CN108203514B (zh) 2016-12-16 2022-11-22 漂莱特（中国）有限公司 使用超疏水膜通过振动喷射生产均匀的聚合物珠粒的方法
CN108327121A (zh) * 2018-01-31 2018-07-27 蚌埠兴力传感系统工程有限公司 一种电缆料冷却装置
GB201820806D0 (en) * 2018-12-20 2019-02-06 Ge Healthcare Bioprocess R&D Ab Large pore agarose
TWI787697B (zh) * 2019-12-30 2022-12-21 財團法人工業技術研究院 外泌體的分離方法、膠體粒子及其製備方法
EP4237534A1 (en) * 2020-10-30 2023-09-06 Corning Incorporated Methods and systems for production of cell culture scaffolds
EP4019125A1 (en) * 2020-12-22 2022-06-29 Sartorius Stedim Biotech GmbH Chromatographic material and method of producing same
SE545486C2 (en) * 2021-07-15 2023-09-26 Bio Works Tech Ab Method for the manufacture of agar or agarose beads using vegetable oil
CN114191848B (zh) * 2021-12-06 2022-12-30 武汉瑞法医疗器械有限公司 琼脂糖微球的清洗方法
CN114539600B (zh) * 2022-03-11 2023-09-01 苏州华诺生物科技有限公司 一种高耐压三级结构的琼脂糖微球及其制备方法

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL65131A0 (en) * 1982-02-28 1982-04-30 Yeda Res & Dev Process for the production of agarose-polyaldehyde beads and their biological applications
SE8604684L (sv) 1986-11-03 1988-05-04 Excorim Kommanditbolag Sett att belegga fasta partiklar med en hydrofil gel samt genom settet belagda partiklar
DK165090D0 (da) * 1990-07-09 1990-07-09 Kem En Tec As Konglomererede partikler
SE9200827D0 (sv) 1992-03-18 1992-03-18 Pharmacia Lkb Biotech Supet porous polysaccharide gels
US5312571A (en) * 1993-01-07 1994-05-17 Norton Company Shaped bodies and the production thereof
US5888497A (en) * 1996-04-03 1999-03-30 The Rogosin Institute Agarose coated agarose beads containing cancer cells that produce material which suppresses cancer cell proliferation
SE9700383D0 (sv) * 1997-02-04 1997-02-04 Pharmacia Biotech Ab An adsorption/separation method and a medium for adsorption/separation
SE9803225D0 (sv) 1998-09-23 1998-09-23 Amersham Pharm Biotech Ab Process for production of polysaccharide beads
DE19920794A1 (de) * 1999-05-06 2000-11-09 Merck Patent Gmbh Verfahren zur Herstellung von Perlpolymerisaten
SE9904344D0 (sv) * 1999-12-01 1999-12-01 Ralf Goeran Andersson Method of producing porous spherical particles
CN1194029C (zh) * 2001-03-24 2005-03-23 天津大学 油水两相法制备磁性琼脂糖凝胶微球的方法
CN1376730A (zh) * 2001-03-27 2002-10-30 内蒙古师范大学 磁性琼脂糖复合微球的制备方法
SE0200010D0 (sv) * 2002-01-02 2002-01-02 Amersham Biosciences Ab A method of producing hierarchical porous beads
WO2004070026A1 (en) 2003-02-07 2004-08-19 Labatt Brewing Company Limited Continuous process for immobilization of yeast in k-carrageenan gel beads
CN1304101C (zh) * 2004-01-12 2007-03-14 中国科学院过程工程研究所 一种尺寸均一的琼脂糖凝胶微球及其制备方法
SG131015A1 (en) 2005-09-15 2007-04-26 Millipore Corp Method and apparatus for making porous agarose beads

Also Published As

Publication number Publication date
EP1764151B1 (en) 2016-04-13
CN1939582B (zh) 2010-12-15
JP2007077397A (ja) 2007-03-29
US20070069408A1 (en) 2007-03-29
US7678302B2 (en) 2010-03-16
US20100227015A1 (en) 2010-09-09
CN1939582A (zh) 2007-04-04
US8177537B2 (en) 2012-05-15
DK1764151T3 (en) 2016-08-01
EP1764151A1 (en) 2007-03-21
ES2582362T3 (es) 2016-09-12
PL1764151T3 (pl) 2016-12-30
JP4662900B2 (ja) 2011-03-30

Similar Documents

Publication Publication Date Title
SG131015A1 (en) Method and apparatus for making porous agarose beads
Keshavarz et al. Analysis of CO2 separation and simulation of a partially wetted hollow fiber membrane contactor
CN105177339B (zh) 一种三维空间有序孔结构泡沫铝及其制备方法
ATE277733T1 (de) Schaumstoff und verfahren zur herstellung
CN105038212A (zh) 氧化石墨烯增强尼龙材料及其制备方法和应用
Magnone et al. High-performance of modified Al2O3 hollow fiber membranes for CO2 absorption at room temperature
ATE364443T1 (de) Verfahren zur herstellung von chemischen absorptionsmitteln und chemischen absorptionmittelszusammensetzung
DE602005006035D1 (de) Vorrichtung und Verfahren zur Bearbeitung von Rahmen mit multiprotokollverwendungsfeldern für ein Kommunikationsnetzwerk
CN103172887A (zh) 一种聚酰胺酸沐浴模式化学亚胺化制造聚酰亚胺薄膜的方法
DE60221896D1 (de) Verfahren zur herstellung hierarchisch poröser kügelchen
DE502004011740D1 (de) Verfahren zur herstellung oberflächenmodifizierter werkstücke
Guglielmelli Research reproducibility and performance evaluation for dependable robots
DE502007006794D1 (de) Verfahren zur Herstellung von Wirkstoffkonzentraten
Boettcher Teaching social conversation skills to children with autism through self-management: An analysis of treatment gains and meaningful outcomes
DE502005001180D1 (de) Folienelement und Verfahren zu dessen Herstellung
DE502005004453D1 (de) Verfahren zum beschichten eines garnes
Arya Drying induced phase separation
CN105033163B (zh) 无机覆膜砂及其制造方法
RU2009107005A (ru) Пористая мембрана из винилиденфторидной смолы и способ ее получения
DE60219987D1 (de) In-line Mischvorrichtung, Verfahren zum Vermischen reaktiver chemischer Lösungen und Verfahren zur Herstellung von Mikrokapseln
RU2015106710A (ru) Шихта и способ алюминотермического получения сплава на основе хрома с ее использованием
Gutul et al. Investigation of an activated local absorption ventilation system
Dawei et al. R esearch and p reparation of high quality and high utilization polycrystalline silicon ingot
TH1801001707A (th) อนุภาคเมทัลออกไซด์และวิธีการผลิตนั้น
Spiniello New Board Members: Meet the Fresh Faces at ChemPlusChem