SG11202106507RA - Substituted 3-((3-aminophenyl)amino)piperidine-2,6-dione compounds, compositions thereof, and methods of treatment therewith - Google Patents
Substituted 3-((3-aminophenyl)amino)piperidine-2,6-dione compounds, compositions thereof, and methods of treatment therewithInfo
- Publication number
- SG11202106507RA SG11202106507RA SG11202106507RA SG11202106507RA SG11202106507RA SG 11202106507R A SG11202106507R A SG 11202106507RA SG 11202106507R A SG11202106507R A SG 11202106507RA SG 11202106507R A SG11202106507R A SG 11202106507RA SG 11202106507R A SG11202106507R A SG 11202106507RA
- Authority
- SG
- Singapore
- Prior art keywords
- aminophenyl
- piperidine
- amino
- substituted
- compositions
- Prior art date
Links
- HWWKOVGSUZFLBU-UHFFFAOYSA-N NC1=CC=CC(NC2C(NC(=O)CC2)=O)=C1 Chemical class NC1=CC=CC(NC2C(NC(=O)CC2)=O)=C1 HWWKOVGSUZFLBU-UHFFFAOYSA-N 0.000 title 1
- 239000000203 mixture Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/92—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with a hetero atom directly attached to the ring nitrogen atom
- C07D211/94—Oxygen atom, e.g. piperidine N-oxide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/30—Oxygen or sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
- C07D491/107—Spiro-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862782298P | 2018-12-19 | 2018-12-19 | |
| US201962879900P | 2019-07-29 | 2019-07-29 | |
| PCT/US2019/067088 WO2020132014A1 (en) | 2018-12-19 | 2019-12-18 | Substituted 3-((3-aminophenyl)amino)piperidine-2,6-dione compounds, compositions thereof, and methods of treatment therewith |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11202106507RA true SG11202106507RA (en) | 2021-07-29 |
Family
ID=71098067
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11202106507RA SG11202106507RA (en) | 2018-12-19 | 2019-12-18 | Substituted 3-((3-aminophenyl)amino)piperidine-2,6-dione compounds, compositions thereof, and methods of treatment therewith |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US11149007B2 (ja) |
| EP (1) | EP3897636A4 (ja) |
| JP (1) | JP7494181B2 (ja) |
| KR (1) | KR20210118816A (ja) |
| CN (1) | CN113453681A (ja) |
| AU (1) | AU2019403207A1 (ja) |
| BR (1) | BR112021011968A2 (ja) |
| CA (1) | CA3124130A1 (ja) |
| CL (1) | CL2021001665A1 (ja) |
| CO (1) | CO2021007973A2 (ja) |
| IL (1) | IL284223A (ja) |
| MX (1) | MX2021007473A (ja) |
| PE (1) | PE20212247A1 (ja) |
| SG (1) | SG11202106507RA (ja) |
| TW (1) | TWI820276B (ja) |
| WO (1) | WO2020132014A1 (ja) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20210118816A (ko) * | 2018-12-19 | 2021-10-01 | 셀진 코포레이션 | 치환된 3-((3-아미노페닐)아미노)피페리딘-2,6-디온 화합물, 이의 조성물, 및 이를 사용한 치료 방법 |
| WO2020132016A1 (en) | 2018-12-19 | 2020-06-25 | Celgene Corporation | Substituted 3-((3-aminophenyl)amino)piperidine-2,6-dione compounds, compositions thereof, and methods of treatment therewith |
| PE20221582A1 (es) | 2019-12-19 | 2022-10-06 | Arvinas Operations Inc | Compuestos y metodos para la degradacion dirigida de receptor de androgenos |
| CN115968293A (zh) * | 2020-06-24 | 2023-04-14 | 新基公司 | Cereblon结合化合物、其组合物及其用于治疗的方法 |
| US11634407B2 (en) * | 2020-06-24 | 2023-04-25 | Celgene Corporation | Cereblon binding compounds, compositions thereof, and methods of treatment therewith |
| KR20230027213A (ko) | 2020-06-24 | 2023-02-27 | 셀진 코포레이션 | 세레블론 결합 화합물, 이의 조성물, 및 이에 의한 치료 방법 |
| US20240025863A1 (en) | 2020-09-16 | 2024-01-25 | Biotheryx, Inc. | Sos1 protein degraders, pharmaceutical compositions thereof, and their therapeutic applications |
| TW202231269A (zh) | 2020-10-23 | 2022-08-16 | 美商拜歐斯瑞克斯公司 | Kras蛋白降解劑、其醫藥組合物及其治療應用 |
| WO2022132603A1 (en) | 2020-12-14 | 2022-06-23 | Biotheryx, Inc. | Pde4 degraders, pharmaceutical compositions, and therapeutic applications |
| CN117545752A (zh) * | 2021-06-25 | 2024-02-09 | 细胞基因公司 | Cereblon结合化合物、其组合物及其用于治疗的方法 |
| EP4359407A1 (en) * | 2021-06-25 | 2024-05-01 | Celgene Corporation | Cereblon binding compounds, compositions thereof, and methods of treatment therewith |
| WO2024102706A1 (en) * | 2022-11-09 | 2024-05-16 | Bristol-Myers Squibb Company | Combination therapy with substituted 3-((3-aminophenyl)amino)piperidine-2,6-dione compounds |
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| FR2768728B1 (fr) | 1997-09-19 | 1999-12-03 | Rhodia Chimie Sa | Procede d'acylation d'un compose aromatique |
| FR2768729A1 (fr) | 1997-09-19 | 1999-03-26 | Rhodia Chimie Sa | Procede d'acylation d'un compose aromatique et complexes catalytiques |
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| WO2020132016A1 (en) | 2018-12-19 | 2020-06-25 | Celgene Corporation | Substituted 3-((3-aminophenyl)amino)piperidine-2,6-dione compounds, compositions thereof, and methods of treatment therewith |
| KR20210118816A (ko) * | 2018-12-19 | 2021-10-01 | 셀진 코포레이션 | 치환된 3-((3-아미노페닐)아미노)피페리딘-2,6-디온 화합물, 이의 조성물, 및 이를 사용한 치료 방법 |
-
2019
- 2019-12-18 KR KR1020217019479A patent/KR20210118816A/ko unknown
- 2019-12-18 TW TW108146514A patent/TWI820276B/zh active
- 2019-12-18 PE PE2021000924A patent/PE20212247A1/es unknown
- 2019-12-18 CA CA3124130A patent/CA3124130A1/en active Pending
- 2019-12-18 CN CN201980092358.2A patent/CN113453681A/zh active Pending
- 2019-12-18 BR BR112021011968-0A patent/BR112021011968A2/pt unknown
- 2019-12-18 SG SG11202106507RA patent/SG11202106507RA/en unknown
- 2019-12-18 JP JP2021535539A patent/JP7494181B2/ja active Active
- 2019-12-18 WO PCT/US2019/067088 patent/WO2020132014A1/en active Application Filing
- 2019-12-18 US US16/719,171 patent/US11149007B2/en active Active
- 2019-12-18 AU AU2019403207A patent/AU2019403207A1/en active Pending
- 2019-12-18 MX MX2021007473A patent/MX2021007473A/es unknown
- 2019-12-18 EP EP19901383.0A patent/EP3897636A4/en active Pending
-
2021
- 2021-06-18 CO CONC2021/0007973A patent/CO2021007973A2/es unknown
- 2021-06-18 CL CL2021001665A patent/CL2021001665A1/es unknown
- 2021-06-20 IL IL284223A patent/IL284223A/en unknown
- 2021-08-16 US US17/403,742 patent/US11873283B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| AU2019403207A1 (en) | 2021-07-15 |
| WO2020132014A1 (en) | 2020-06-25 |
| CA3124130A1 (en) | 2020-06-25 |
| EP3897636A1 (en) | 2021-10-27 |
| CO2021007973A2 (es) | 2021-09-09 |
| US20230002321A1 (en) | 2023-01-05 |
| CN113453681A (zh) | 2021-09-28 |
| US20200199073A1 (en) | 2020-06-25 |
| EP3897636A4 (en) | 2022-09-07 |
| US11149007B2 (en) | 2021-10-19 |
| MX2021007473A (es) | 2021-08-05 |
| TW202039435A (zh) | 2020-11-01 |
| BR112021011968A2 (pt) | 2021-09-08 |
| JP7494181B2 (ja) | 2024-06-03 |
| KR20210118816A (ko) | 2021-10-01 |
| TWI820276B (zh) | 2023-11-01 |
| US11873283B2 (en) | 2024-01-16 |
| PE20212247A1 (es) | 2021-11-24 |
| IL284223A (en) | 2021-08-31 |
| JP2022514344A (ja) | 2022-02-10 |
| CL2021001665A1 (es) | 2022-01-14 |
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