SG11202102954QA - Simultaneous, sequencing-based analysis of proteins, nucleosomes, and cell-free nucleic acids from a single biological sample - Google Patents

Simultaneous, sequencing-based analysis of proteins, nucleosomes, and cell-free nucleic acids from a single biological sample

Info

Publication number
SG11202102954QA
SG11202102954QA SG11202102954QA SG11202102954QA SG11202102954QA SG 11202102954Q A SG11202102954Q A SG 11202102954QA SG 11202102954Q A SG11202102954Q A SG 11202102954QA SG 11202102954Q A SG11202102954Q A SG 11202102954QA SG 11202102954Q A SG11202102954Q A SG 11202102954QA
Authority
SG
Singapore
Prior art keywords
nucleosomes
sequencing
proteins
simultaneous
cell
Prior art date
Application number
SG11202102954QA
Other languages
English (en)
Inventor
Patrick A Arensdorf
Damek Spacek
Christopher E Ellison
Samuel Levy
Original Assignee
Bluestar Genomics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bluestar Genomics Inc filed Critical Bluestar Genomics Inc
Publication of SG11202102954QA publication Critical patent/SG11202102954QA/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1065—Preparation or screening of tagged libraries, e.g. tagged microorganisms by STM-mutagenesis, tagged polynucleotides, gene tags
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6804—Nucleic acid analysis using immunogens
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Plant Pathology (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
SG11202102954QA 2018-10-04 2019-10-03 Simultaneous, sequencing-based analysis of proteins, nucleosomes, and cell-free nucleic acids from a single biological sample SG11202102954QA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201862741473P 2018-10-04 2018-10-04
PCT/US2019/054582 WO2020072829A2 (en) 2018-10-04 2019-10-03 Simultaneous, sequencing-based analysis of proteins, nucleosomes, and cell-free nucleic acids from a single biological sample

Publications (1)

Publication Number Publication Date
SG11202102954QA true SG11202102954QA (en) 2021-04-29

Family

ID=68296828

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202102954QA SG11202102954QA (en) 2018-10-04 2019-10-03 Simultaneous, sequencing-based analysis of proteins, nucleosomes, and cell-free nucleic acids from a single biological sample

Country Status (9)

Country Link
US (1) US12540319B2 (https=)
EP (1) EP3861132A2 (https=)
JP (1) JP2022504078A (https=)
CN (1) CN113166796A (https=)
AU (1) AU2019354789A1 (https=)
CA (1) CA3114606A1 (https=)
MX (1) MX2021003847A (https=)
SG (1) SG11202102954QA (https=)
WO (1) WO2020072829A2 (https=)

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EP4370711A4 (en) * 2021-07-12 2025-07-02 Univ Pennsylvania MODIFIED ADAPTERS FOR ENZYMATIC DEAMINATION OF DNA AND METHODS OF USE THEREOF FOR EPIGENETIC SEQUENCING OF FREE AND IMMOBILIZED DNA
US20240301466A1 (en) * 2021-07-15 2024-09-12 University Of Washington Efficient duplex sequencing using high fidelity next generation sequencing reads
US20230086611A1 (en) * 2021-09-23 2023-03-23 Genomic Testing Cooperative, LCA Compositions and Methods for Targeted NGS Sequencing of cfRNA and cfTNA
CN118139987A (zh) * 2021-09-23 2024-06-04 基因组检测合作社公司 用于cfrna和cftna靶向ngs测序的组合物和方法
WO2023097295A1 (en) * 2021-11-24 2023-06-01 Alida Biosciences, Inc. Rna and dna analysis using engineered surfaces
CN114934110A (zh) * 2022-06-15 2022-08-23 江西烈冰生物科技有限公司 用于获取基因表达的原始位置的生物芯片、试剂盒及方法
AU2023384167A1 (en) * 2022-11-23 2025-04-24 Alida Biosciences, Inc. Chromatin profiling compositions and methods
WO2024112816A1 (en) 2022-11-23 2024-05-30 University Of Iowa Research Foundation Therapeutic compounds and methods
CN116403645B (zh) * 2023-03-03 2024-01-09 阿里巴巴（中国）有限公司 转录因子结合位点的预测方法及装置
WO2026024692A1 (en) * 2024-07-24 2026-01-29 Guardant Health, Inc. Direct methylation single-base resolution sequencing of enriched unmethylated dna

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Also Published As

Publication number Publication date
CN113166796A (zh) 2021-07-23
WO2020072829A3 (en) 2020-08-13
US20210380971A1 (en) 2021-12-09
MX2021003847A (es) 2021-05-27
JP2022504078A (ja) 2022-01-13
WO2020072829A2 (en) 2020-04-09
AU2019354789A1 (en) 2021-05-27
EP3861132A2 (en) 2021-08-11
CA3114606A1 (en) 2020-04-09
US12540319B2 (en) 2026-02-03

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