CN113166796A - 来自单个生物样品的蛋白质、核糖体和无细胞核酸的同时基于测序的分析 - Google Patents

来自单个生物样品的蛋白质、核糖体和无细胞核酸的同时基于测序的分析 Download PDF

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CN113166796A
CN113166796A CN201980077845.1A CN201980077845A CN113166796A CN 113166796 A CN113166796 A CN 113166796A CN 201980077845 A CN201980077845 A CN 201980077845A CN 113166796 A CN113166796 A CN 113166796A
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dna
sequence
adaptor
nucleic acid
sample
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Chinese (zh)
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P.A.阿伦斯多夫
D.斯帕塞克
C.E.艾莉森
S.莱维
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ClearNote Health Inc
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Bluestar Genomics Inc
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1065—Preparation or screening of tagged libraries, e.g. tagged microorganisms by STM-mutagenesis, tagged polynucleotides, gene tags
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6804—Nucleic acid analysis using immunogens
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay

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  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CN201980077845.1A 2018-10-04 2019-10-03 来自单个生物样品的蛋白质、核糖体和无细胞核酸的同时基于测序的分析 Pending CN113166796A (zh)

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US201862741473P 2018-10-04 2018-10-04
US62/741,473 2018-10-04
PCT/US2019/054582 WO2020072829A2 (en) 2018-10-04 2019-10-03 Simultaneous, sequencing-based analysis of proteins, nucleosomes, and cell-free nucleic acids from a single biological sample

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US (1) US12540319B2 (https=)
EP (1) EP3861132A2 (https=)
JP (1) JP2022504078A (https=)
CN (1) CN113166796A (https=)
AU (1) AU2019354789A1 (https=)
CA (1) CA3114606A1 (https=)
MX (1) MX2021003847A (https=)
SG (1) SG11202102954QA (https=)
WO (1) WO2020072829A2 (https=)

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CN114934110A (zh) * 2022-06-15 2022-08-23 江西烈冰生物科技有限公司 用于获取基因表达的原始位置的生物芯片、试剂盒及方法
CN118139987A (zh) * 2021-09-23 2024-06-04 基因组检测合作社公司 用于cfrna和cftna靶向ngs测序的组合物和方法

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CN113517026B (zh) * 2021-06-16 2022-08-19 苏州拉索生物芯片科技有限公司 应用于生物制品的标签序列的生成方法、系统、智能终端及计算机可读存储介质
EP4370711A4 (en) * 2021-07-12 2025-07-02 Univ Pennsylvania MODIFIED ADAPTERS FOR ENZYMATIC DEAMINATION OF DNA AND METHODS OF USE THEREOF FOR EPIGENETIC SEQUENCING OF FREE AND IMMOBILIZED DNA
US20240301466A1 (en) * 2021-07-15 2024-09-12 University Of Washington Efficient duplex sequencing using high fidelity next generation sequencing reads
US20230086611A1 (en) * 2021-09-23 2023-03-23 Genomic Testing Cooperative, LCA Compositions and Methods for Targeted NGS Sequencing of cfRNA and cfTNA
WO2023097295A1 (en) * 2021-11-24 2023-06-01 Alida Biosciences, Inc. Rna and dna analysis using engineered surfaces
AU2023384167A1 (en) * 2022-11-23 2025-04-24 Alida Biosciences, Inc. Chromatin profiling compositions and methods
WO2024112816A1 (en) 2022-11-23 2024-05-30 University Of Iowa Research Foundation Therapeutic compounds and methods
CN116403645B (zh) * 2023-03-03 2024-01-09 阿里巴巴（中国）有限公司 转录因子结合位点的预测方法及装置
WO2026024692A1 (en) * 2024-07-24 2026-01-29 Guardant Health, Inc. Direct methylation single-base resolution sequencing of enriched unmethylated dna

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CN118139987A (zh) * 2021-09-23 2024-06-04 基因组检测合作社公司 用于cfrna和cftna靶向ngs测序的组合物和方法
CN114934110A (zh) * 2022-06-15 2022-08-23 江西烈冰生物科技有限公司 用于获取基因表达的原始位置的生物芯片、试剂盒及方法

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US20210380971A1 (en) 2021-12-09
MX2021003847A (es) 2021-05-27
JP2022504078A (ja) 2022-01-13
WO2020072829A2 (en) 2020-04-09
AU2019354789A1 (en) 2021-05-27
SG11202102954QA (en) 2021-04-29
EP3861132A2 (en) 2021-08-11
CA3114606A1 (en) 2020-04-09
US12540319B2 (en) 2026-02-03

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