SG11202013164RA - Anti-mesothelin antibodies - Google Patents
Anti-mesothelin antibodiesInfo
- Publication number
- SG11202013164RA SG11202013164RA SG11202013164RA SG11202013164RA SG11202013164RA SG 11202013164R A SG11202013164R A SG 11202013164RA SG 11202013164R A SG11202013164R A SG 11202013164RA SG 11202013164R A SG11202013164R A SG 11202013164RA SG 11202013164R A SG11202013164R A SG 11202013164RA
- Authority
- SG
- Singapore
- Prior art keywords
- mesothelin antibodies
- mesothelin
- antibodies
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2878—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
- G01N33/57496—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving intracellular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/52—Constant or Fc region; Isotype
- C07K2317/524—CH2 domain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/52—Constant or Fc region; Isotype
- C07K2317/526—CH3 domain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/55—Fab or Fab'
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/71—Decreased effector function due to an Fc-modification
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/72—Increased effector function due to an Fc-modification
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
- C07K2317/732—Antibody-dependent cellular cytotoxicity [ADCC]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/94—Stability, e.g. half-life, pH, temperature or enzyme-resistance
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Cell Biology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Oncology (AREA)
- General Physics & Mathematics (AREA)
- Microbiology (AREA)
- Hospice & Palliative Care (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- Pathology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1811415.7A GB201811415D0 (en) | 2018-07-12 | 2018-07-12 | Anti-Mesothelin Anti bodies |
| PCT/EP2019/068800 WO2020011970A1 (fr) | 2018-07-12 | 2019-07-12 | Anticorps anti-mésothéline |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11202013164RA true SG11202013164RA (en) | 2021-01-28 |
Family
ID=63273221
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11202013164RA SG11202013164RA (en) | 2018-07-12 | 2019-07-12 | Anti-mesothelin antibodies |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US20220267421A1 (fr) |
| EP (1) | EP3820908A1 (fr) |
| JP (2) | JP7431211B2 (fr) |
| KR (1) | KR20210030957A (fr) |
| CN (1) | CN112703205B (fr) |
| AU (1) | AU2019303030A1 (fr) |
| BR (1) | BR112021000399A2 (fr) |
| CA (1) | CA3105995A1 (fr) |
| GB (1) | GB201811415D0 (fr) |
| IL (1) | IL280003A (fr) |
| MX (1) | MX2021000392A (fr) |
| SG (1) | SG11202013164RA (fr) |
| TW (1) | TWI840386B (fr) |
| WO (1) | WO2020011970A1 (fr) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB201612520D0 (en) | 2016-07-19 | 2016-08-31 | F-Star Beta Ltd | Binding molecules |
| MA52366A (fr) | 2018-04-25 | 2021-03-03 | Prometheus Biosciences Inc | Anticorps anti-tl1a optimisés |
| GB201811408D0 (en) | 2018-07-12 | 2018-08-29 | F Star Beta Ltd | CD137 Binding Molecules |
| AU2020371725A1 (en) | 2019-10-24 | 2022-05-26 | Cedars-Sinai Medical Center | Humanized antibodies to TNF-like ligand 1A (TL1A) and uses thereof |
| EP4132969A4 (fr) * | 2020-04-07 | 2024-05-01 | Fred Hutchinson Cancer Center | Molécules de liaison à l'antigène anti-mésothéline et leurs utilisations |
| CN111560072B (zh) * | 2020-07-16 | 2020-12-11 | 上海恒润达生生物科技有限公司 | 抗人msln抗体以及靶向msln的免疫效应细胞 |
| CN117412991A (zh) * | 2021-06-18 | 2024-01-16 | 南京再明医药有限公司 | 抗人msln人源化抗体及其应用 |
| TW202321296A (zh) | 2021-10-06 | 2023-06-01 | 美商鏈接免疫療法公司 | 抗間皮素抗原結合分子及其用途 |
| CN115991782A (zh) * | 2021-10-18 | 2023-04-21 | 普米斯生物技术(珠海)有限公司 | 抗间皮素纳米抗体及其用途 |
| CN114423789B (zh) * | 2021-12-24 | 2022-09-30 | 浙江时迈药业有限公司 | 针对间皮素的抗体及其用途 |
| TW202413421A (zh) * | 2022-07-11 | 2024-04-01 | 中國商諾納生物（蘇州）有限公司 | 抗間皮素抗體 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS61134325A (ja) | 1984-12-04 | 1986-06-21 | Teijin Ltd | ハイブリツド抗体遺伝子の発現方法 |
| GB8607679D0 (en) | 1986-03-27 | 1986-04-30 | Winter G P | Recombinant dna product |
| EA018897B1 (ru) | 2005-01-05 | 2013-11-29 | Ф-Стар Биотехнологише Форшунгс- Унд Энтвиклунгсгез.М.Б.Х. | Молекулы иммуноглобулина, содержащие модифицированные участки структурных петель, обладающие свойством связывания, и способ их получения |
| EP3178850B1 (fr) | 2005-10-11 | 2021-01-13 | Amgen Research (Munich) GmbH | Compositions comprenant des anticorps spécifiques aux espèces croisées et leurs utilisations |
| KR101559599B1 (ko) | 2007-11-26 | 2015-10-12 | 바이엘 인텔렉쳐 프로퍼티 게엠베하 | 항-메소텔린 항체 및 이의 용도 |
| EP2113255A1 (fr) | 2008-05-02 | 2009-11-04 | f-star Biotechnologische Forschungs- und Entwicklungsges.m.b.H. | Immunoglobuline cytotoxique |
| CN102482701B (zh) | 2009-09-16 | 2015-05-13 | 免疫医疗公司 | I类抗-cea抗体及其使用 |
| EA201790664A1 (ru) | 2010-12-20 | 2017-07-31 | Дженентек, Инк. | Антитела против мезотелина и иммуноконъюгаты |
| EP2900695B1 (fr) | 2012-09-27 | 2018-01-17 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Anticorps dirigés contre la mésothéline et procédés d'induction d'une activité anticancéreuse puissante |
| CA2903258C (fr) * | 2013-03-15 | 2019-11-26 | Amgen Inc. | Anticorps heterodimeres bispecifiques |
| KR101782487B1 (ko) * | 2015-09-24 | 2017-09-27 | 재단법인 목암생명과학연구소 | 신규 항-메소텔린 항체 및 이를 포함하는 조성물 |
| EP3445788B1 (fr) * | 2016-04-22 | 2022-01-19 | Alligator Bioscience AB | Nouveaux polypeptides bispécifiques contre cd137 |
| TW201806972A (zh) | 2016-05-27 | 2018-03-01 | 美商艾伯維生物醫療股份有限公司 | 雙特異性結合蛋白 |
| CN107523546A (zh) * | 2016-06-20 | 2017-12-29 | 上海细胞治疗研究院 | 一种高效稳定表达抗体的nk细胞及其用途 |
-
2018
- 2018-07-12 GB GBGB1811415.7A patent/GB201811415D0/en not_active Ceased
-
2019
- 2019-07-12 AU AU2019303030A patent/AU2019303030A1/en active Pending
- 2019-07-12 TW TW108124779A patent/TWI840386B/zh active
- 2019-07-12 CA CA3105995A patent/CA3105995A1/fr active Pending
- 2019-07-12 JP JP2021500837A patent/JP7431211B2/ja active Active
- 2019-07-12 BR BR112021000399-1A patent/BR112021000399A2/pt unknown
- 2019-07-12 KR KR1020217003612A patent/KR20210030957A/ko unknown
- 2019-07-12 SG SG11202013164RA patent/SG11202013164RA/en unknown
- 2019-07-12 WO PCT/EP2019/068800 patent/WO2020011970A1/fr active Application Filing
- 2019-07-12 EP EP19748736.6A patent/EP3820908A1/fr active Pending
- 2019-07-12 CN CN201980060142.8A patent/CN112703205B/zh active Active
- 2019-07-12 MX MX2021000392A patent/MX2021000392A/es unknown
- 2019-07-12 US US17/259,677 patent/US20220267421A1/en active Pending
-
2021
- 2021-01-07 IL IL280003A patent/IL280003A/en unknown
-
2024
- 2024-02-01 JP JP2024013969A patent/JP2024059643A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP3820908A1 (fr) | 2021-05-19 |
| TW202019971A (zh) | 2020-06-01 |
| AU2019303030A1 (en) | 2021-02-25 |
| MX2021000392A (es) | 2021-05-27 |
| CN112703205B (zh) | 2024-10-18 |
| WO2020011970A1 (fr) | 2020-01-16 |
| JP2021524278A (ja) | 2021-09-13 |
| JP7431211B2 (ja) | 2024-02-14 |
| IL280003A (en) | 2021-03-01 |
| US20220267421A1 (en) | 2022-08-25 |
| KR20210030957A (ko) | 2021-03-18 |
| CA3105995A1 (fr) | 2020-01-16 |
| TWI840386B (zh) | 2024-05-01 |
| CN112703205A (zh) | 2021-04-23 |
| JP2024059643A (ja) | 2024-05-01 |
| GB201811415D0 (en) | 2018-08-29 |
| BR112021000399A2 (pt) | 2021-04-06 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IL268517A (en) | Anti-tigit antibodies | |
| IL280780A (en) | Anti-TIGIT antibodies | |
| IL272227A (en) | ANTI-TIGIT antibodies | |
| IL268620A (en) | Antibodies against LAG3 | |
| IL280013A (en) | Anti-IL36R antibodies | |
| HUE067040T2 (hu) | Anti-SIRPalfa antitestek | |
| IL280003A (en) | Anti-mesothelin antibodies | |
| GB201709808D0 (en) | Antibodies | |
| IL279352A (en) | IL-11RA antibodies | |
| IL278010A (en) | Antibodies to galectin 10 | |
| PL3606961T3 (pl) | Przeciwciała garp-tgf-beta | |
| IL277030A (en) | Antibodies | |
| SG11202106171WA (en) | Anti-btla antibodies | |
| IL281594A (en) | Antibodies against KLRG1 | |
| GB201720970D0 (en) | Antibodies | |
| IL275187A (en) | Anti-alpha-synuclein antibodies | |
| IL271067A (en) | Anti-trkb antibodies | |
| GB201806084D0 (en) | Antibodies | |
| GB201711785D0 (en) | Antibodies | |
| SG11202105718TA (en) | Modified antibodies | |
| GB201819952D0 (en) | Antibodies | |
| GB201817311D0 (en) | Antibodies | |
| GB201817313D0 (en) | Antibodies | |
| GB201817312D0 (en) | Antibodies | |
| GB201817309D0 (en) | Antibodies |