SG11202009264WA - Use of antibody drug conjugates comprising tubulin disrupting agents to treat solid tumor - Google Patents

Use of antibody drug conjugates comprising tubulin disrupting agents to treat solid tumor

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Publication number
SG11202009264WA
SG11202009264WA SG11202009264WA SG11202009264WA SG11202009264WA SG 11202009264W A SG11202009264W A SG 11202009264WA SG 11202009264W A SG11202009264W A SG 11202009264WA SG 11202009264W A SG11202009264W A SG 11202009264WA SG 11202009264W A SG11202009264W A SG 11202009264WA
Authority
SG
Singapore
Prior art keywords
solid tumor
drug conjugates
antibody drug
disrupting agents
treat solid
Prior art date
Application number
SG11202009264WA
Other languages
English (en)
Inventor
Anthony Cao
Shyra Gardai
Original Assignee
Seattle Genetics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Seattle Genetics Inc filed Critical Seattle Genetics Inc
Publication of SG11202009264WA publication Critical patent/SG11202009264WA/en

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    • A61K47/6889—Conjugates wherein the antibody being the modifying agent and wherein the linker, binder or spacer confers particular properties to the conjugates, e.g. peptidic enzyme-labile linkers or acid-labile linkers, providing for an acid-labile immuno conjugate wherein the drug may be released from its antibody conjugated part in an acidic, e.g. tumoural or environment
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    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

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