SG11202008699WA - Anti-cd25 for tumour specific cell depletion - Google Patents

Anti-cd25 for tumour specific cell depletion

Info

Publication number
SG11202008699WA
SG11202008699WA SG11202008699WA SG11202008699WA SG11202008699WA SG 11202008699W A SG11202008699W A SG 11202008699WA SG 11202008699W A SG11202008699W A SG 11202008699WA SG 11202008699W A SG11202008699W A SG 11202008699WA SG 11202008699W A SG11202008699W A SG 11202008699WA
Authority
SG
Singapore
Prior art keywords
specific cell
cell depletion
tumour specific
tumour
depletion
Prior art date
Application number
SG11202008699WA
Other languages
English (en)
Inventor
Anne Goubier
Corzo Beatriz Goyenechea
Josephine Salimu
Kevin Moulder
Pascal Merchiers
Mark Brown
James Geoghegan
Bianka Prinz
Sergio Quezada
Original Assignee
Tusk Therapeutics Ltd
Cancer Research Tech Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB1804028.7A external-priority patent/GB201804028D0/en
Priority claimed from GBGB1804027.9A external-priority patent/GB201804027D0/en
Priority claimed from GBGB1804029.5A external-priority patent/GB201804029D0/en
Priority claimed from PCT/EP2018/056312 external-priority patent/WO2018167104A1/en
Application filed by Tusk Therapeutics Ltd, Cancer Research Tech Ltd filed Critical Tusk Therapeutics Ltd
Publication of SG11202008699WA publication Critical patent/SG11202008699WA/en

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    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
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    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
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    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39541—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against normal tissues, cells
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    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
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    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
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    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2878—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
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    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
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    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
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    • C—CHEMISTRY; METALLURGY
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    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
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    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
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    • C07K2317/622—Single chain antibody (scFv)
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    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
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    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C07K2317/732—Antibody-dependent cellular cytotoxicity [ADCC]
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    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
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SG11202008699WA 2018-03-13 2019-03-13 Anti-cd25 for tumour specific cell depletion SG11202008699WA (en)

Applications Claiming Priority (10)

Application Number Priority Date Filing Date Title
US201862642230P 2018-03-13 2018-03-13
US201862642243P 2018-03-13 2018-03-13
US201862642248P 2018-03-13 2018-03-13
US201862642218P 2018-03-13 2018-03-13
US201862642232P 2018-03-13 2018-03-13
GBGB1804028.7A GB201804028D0 (en) 2018-03-13 2018-03-13 Anti-CD25 antibody agents
GBGB1804027.9A GB201804027D0 (en) 2018-03-13 2018-03-13 Anti-CD25 antibody agents
GBGB1804029.5A GB201804029D0 (en) 2018-03-13 2018-03-13 Anti-CD25 antibody agents
PCT/EP2018/056312 WO2018167104A1 (en) 2017-03-17 2018-03-13 Fc-optimized anti-cd25 for tumour specific cell depletion
PCT/EP2019/056249 WO2019175217A1 (en) 2018-03-13 2019-03-13 Anti-cd25 for tumour specific cell depletion

Publications (1)

Publication Number Publication Date
SG11202008699WA true SG11202008699WA (en) 2020-10-29

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SG11202008699WA SG11202008699WA (en) 2018-03-13 2019-03-13 Anti-cd25 for tumour specific cell depletion
SG11202008784RA SG11202008784RA (en) 2018-03-13 2019-03-13 Anti-cd25 for tumour specific cell depletion
SG11202008733YA SG11202008733YA (en) 2018-03-13 2019-03-13 Anti-cd25 for tumour specific cell depletion

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SG11202008733YA SG11202008733YA (en) 2018-03-13 2019-03-13 Anti-cd25 for tumour specific cell depletion

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US (11) US10752691B2 (lt)
EP (8) EP3765502A1 (lt)
JP (8) JP2021515565A (lt)
KR (3) KR20200131286A (lt)
CN (8) CN112020515A (lt)
AU (3) AU2019233576A1 (lt)
BR (3) BR112020016519A2 (lt)
CA (3) CA3088659A1 (lt)
CR (3) CR20200467A (lt)
MA (1) MA51993A (lt)
PE (3) PE20210288A1 (lt)
SG (3) SG11202008699WA (lt)
TW (3) TW201940515A (lt)
WO (8) WO2019175220A1 (lt)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11371066B2 (en) 2015-07-13 2022-06-28 Modular Genetics, Inc. Generation of acyl alcohols
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