SG11202006233XA - Diagnostic compositions for pet imaging, a method for manufacturing the diagnostic composition and its use in diagnostics - Google Patents

Diagnostic compositions for pet imaging, a method for manufacturing the diagnostic composition and its use in diagnostics

Info

Publication number
SG11202006233XA
SG11202006233XA SG11202006233XA SG11202006233XA SG11202006233XA SG 11202006233X A SG11202006233X A SG 11202006233XA SG 11202006233X A SG11202006233X A SG 11202006233XA SG 11202006233X A SG11202006233X A SG 11202006233XA SG 11202006233X A SG11202006233X A SG 11202006233XA
Authority
SG
Singapore
Prior art keywords
diagnostic
diagnostics
manufacturing
pet imaging
compositions
Prior art date
Application number
SG11202006233XA
Other languages
English (en)
Inventor
Melean Johnny Castillo
Thomas Betzel
Mathias Berndt
Hanno Schieferstein
Heiko Kroth
Jérôme Molette
Vincent Darmency
Emanuele Gabellieri
Original Assignee
Ac Immune Sa
Life Molecular Imaging Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ac Immune Sa, Life Molecular Imaging Sa filed Critical Ac Immune Sa
Publication of SG11202006233XA publication Critical patent/SG11202006233XA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/041Heterocyclic compounds
    • A61K51/044Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
    • A61K51/0455Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12Carboxylic acids; Salts or anhydrides thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B59/00Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
    • C07B59/002Heterocyclic compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14Ortho-condensed systems
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/60Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances involving radioactive labelled substances
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G01N33/6896Neurological disorders, e.g. Alzheimer's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00Preparations for testing in vivo
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/28Neurological disorders
    • G01N2800/2814Dementia; Cognitive disorders
    • G01N2800/2821Alzheimer

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Hematology (AREA)
  • Physics & Mathematics (AREA)
  • Urology & Nephrology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Inorganic Chemistry (AREA)
  • Pathology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Optics & Photonics (AREA)
  • Food Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicinal Preparation (AREA)
  • Macromonomer-Based Addition Polymer (AREA)
  • Polymerisation Methods In General (AREA)
SG11202006233XA 2018-01-24 2019-01-22 Diagnostic compositions for pet imaging, a method for manufacturing the diagnostic composition and its use in diagnostics SG11202006233XA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP18153327 2018-01-24
PCT/EP2019/051497 WO2019145293A1 (en) 2018-01-24 2019-01-22 Diagnostic compositions for pet imaging, a method for manufacturing the diagnostic composition and its use in diagnostics

Publications (1)

Publication Number Publication Date
SG11202006233XA true SG11202006233XA (en) 2020-08-28

Family

ID=61192647

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202006233XA SG11202006233XA (en) 2018-01-24 2019-01-22 Diagnostic compositions for pet imaging, a method for manufacturing the diagnostic composition and its use in diagnostics

Country Status (14)

Country Link
US (1) US20210047327A1 (zh)
EP (1) EP3743115A1 (zh)
JP (1) JP7260552B2 (zh)
KR (1) KR20200113241A (zh)
CN (1) CN111712265B (zh)
AU (1) AU2019210976B2 (zh)
BR (1) BR112020014594A8 (zh)
CA (1) CA3088232A1 (zh)
EA (1) EA202091766A1 (zh)
IL (1) IL275990B1 (zh)
MX (1) MX2020007487A (zh)
SG (1) SG11202006233XA (zh)
TW (1) TWI808119B (zh)
WO (1) WO2019145293A1 (zh)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111868062B (zh) * 2018-01-24 2023-07-07 Ac免疫有限公司 制备显像化合物的方法
GB202005282D0 (en) * 2020-04-09 2020-05-27 Blue Earth Diagnostics Ltd Pharmaceutical Formulations
CN114832118B (zh) * 2022-07-04 2022-09-27 北京先通国际医药科技股份有限公司 化合物i液体组合物、制备方法及其用途
CN114835690B (zh) * 2022-07-04 2022-09-27 北京先通国际医药科技股份有限公司 含化合物i的液体组合物的制备方法、及在心肌灌注pet显像中的用途

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2678020C (en) * 2007-02-13 2015-03-24 Nihon Medi-Physics Co., Ltd. Method for production of radiation diagnostic imaging agent
AU2008324186B2 (en) * 2007-11-07 2014-02-13 Ge Healthcare Bv Stabilization of radiopharmaceuticals
PE20120007A1 (es) 2008-12-31 2012-01-16 Avid Radiopharmaceuticals Inc Sintesis de estirilpiridinas radiomarcadas con 18f a partir de precursores de tosilato y composiciones farmaceuticas estables de estas
US20120328521A1 (en) 2009-12-23 2012-12-27 Piramal Imaging Sa Formulations suitable for pet imaging with hydrophobic pet agents
DK2558446T5 (da) 2010-04-16 2019-12-09 Ac Immune Sa Nye forbindelser til behandling af sygdomme associerede med amyloid- eller amyloidlignende proteiner
ES2657121T3 (es) * 2013-10-08 2018-03-01 F. Hoffmann-La Roche Ag Derivados de diazacarbazol como ligandos tau-pet
WO2015110263A1 (en) * 2014-01-21 2015-07-30 Ac Immune Sa Carbazole and carboline compounds for use in the diagnosis, treatment, alleviation or prevention of disorders associated with amyloid or amyolid-like proteins
CN107198780A (zh) * 2016-03-18 2017-09-26 南京江原安迪科正电子研究发展有限公司 放射性药物组合物及其制备方法、应用
SG11201811311VA (en) * 2016-07-22 2019-01-30 Ac Immune Sa Compounds for imaging tau protein aggregates
WO2018015546A1 (en) * 2016-07-22 2018-01-25 Ac Immune S.A. Compounds for imaging tau protein aggregates
WO2018024642A1 (en) * 2016-08-02 2018-02-08 Ucb Biopharma Sprl 9h-pyrrolo-dipyridine derivatives

Also Published As

Publication number Publication date
CA3088232A1 (en) 2019-08-01
TWI808119B (zh) 2023-07-11
EP3743115A1 (en) 2020-12-02
US20210047327A1 (en) 2021-02-18
IL275990A (en) 2020-08-31
CN111712265B (zh) 2024-02-09
JP7260552B2 (ja) 2023-04-18
WO2019145293A1 (en) 2019-08-01
AU2019210976B2 (en) 2024-04-18
CN111712265A (zh) 2020-09-25
EA202091766A1 (ru) 2021-02-18
TW201932108A (zh) 2019-08-16
KR20200113241A (ko) 2020-10-06
BR112020014594A8 (pt) 2022-12-13
JP2021512070A (ja) 2021-05-13
AU2019210976A1 (en) 2020-07-23
BR112020014594A2 (pt) 2020-12-01
MX2020007487A (es) 2020-09-14
IL275990B1 (en) 2024-04-01

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