SG11202002973WA - Griseofulvin compound and pharmaceutical use thereof - Google Patents
Griseofulvin compound and pharmaceutical use thereofInfo
- Publication number
- SG11202002973WA SG11202002973WA SG11202002973WA SG11202002973WA SG11202002973WA SG 11202002973W A SG11202002973W A SG 11202002973WA SG 11202002973W A SG11202002973W A SG 11202002973WA SG 11202002973W A SG11202002973W A SG 11202002973WA SG 11202002973W A SG11202002973W A SG 11202002973WA
- Authority
- SG
- Singapore
- Prior art keywords
- pharmaceutical use
- griseofulvin
- compound
- griseofulvin compound
- pharmaceutical
- Prior art date
Links
- IIUZTXTZRGLYTI-UHFFFAOYSA-N Dihydrogriseofulvin Natural products COC1CC(=O)CC(C)C11C(=O)C(C(OC)=CC(OC)=C2Cl)=C2O1 IIUZTXTZRGLYTI-UHFFFAOYSA-N 0.000 title 1
- -1 Griseofulvin compound Chemical class 0.000 title 1
- UXWOXTQWVMFRSE-UHFFFAOYSA-N Griseoviridin Natural products O=C1OC(C)CC=C(C(NCC=CC=CC(O)CC(O)C2)=O)SCC1NC(=O)C1=COC2=N1 UXWOXTQWVMFRSE-UHFFFAOYSA-N 0.000 title 1
- DDUHZTYCFQRHIY-UHFFFAOYSA-N Negwer: 6874 Natural products COC1=CC(=O)CC(C)C11C(=O)C(C(OC)=CC(OC)=C2Cl)=C2O1 DDUHZTYCFQRHIY-UHFFFAOYSA-N 0.000 title 1
- 229960002867 griseofulvin Drugs 0.000 title 1
Classifications
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- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
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- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/351—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom not condensed with another ring
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- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
- A61K31/4155—1,2-Diazoles non condensed and containing further heterocyclic rings
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- A61K31/42—Oxazoles
- A61K31/424—Oxazoles condensed with heterocyclic ring systems, e.g. clavulanic acid
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- A61K31/4245—Oxadiazoles
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- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
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- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/94—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom spiro-condensed with carbocyclic rings or ring systems, e.g. griseofulvins
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- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
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- C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/10—Oxygen atoms
- C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
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- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
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- C07D405/10—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing aromatic rings
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- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
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- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
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- C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
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Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Epidemiology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Addiction (AREA)
- Psychology (AREA)
- Rheumatology (AREA)
- Anesthesiology (AREA)
- Physical Education & Sports Medicine (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Hospice & Palliative Care (AREA)
- Child & Adolescent Psychology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Obesity (AREA)
- Ophthalmology & Optometry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Furan Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
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JP2017191690 | 2017-09-29 | ||
PCT/JP2018/036160 WO2019065928A1 (ja) | 2017-09-29 | 2018-09-28 | グリセオフルビン化合物と医薬用途 |
Publications (1)
Publication Number | Publication Date |
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SG11202002973WA true SG11202002973WA (en) | 2020-04-29 |
Family
ID=65902532
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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SG11202002973WA SG11202002973WA (en) | 2017-09-29 | 2018-09-28 | Griseofulvin compound and pharmaceutical use thereof |
Country Status (14)
Country | Link |
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US (2) | US11407746B2 (de) |
EP (1) | EP3689857A4 (de) |
JP (1) | JP7102426B2 (de) |
KR (1) | KR20200062243A (de) |
CN (1) | CN111295378A (de) |
AU (1) | AU2018342423B2 (de) |
BR (1) | BR112020006239A2 (de) |
CA (1) | CA3076885A1 (de) |
IL (1) | IL273339B1 (de) |
MX (1) | MX2020003383A (de) |
PH (1) | PH12020550168A1 (de) |
SG (1) | SG11202002973WA (de) |
TW (1) | TWI811243B (de) |
WO (1) | WO2019065928A1 (de) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2017170623A1 (ja) | 2016-03-30 | 2017-10-05 | 第一三共株式会社 | グリセオフルビン化合物 |
TWI811243B (zh) | 2017-09-29 | 2023-08-11 | 日商第一三共股份有限公司 | 灰黃黴素化合物及醫藥用途 |
AU2020341464A1 (en) * | 2019-09-05 | 2022-04-21 | Trevena, Inc. | Methods of treating epilepsy using the same |
AU2021247173A1 (en) * | 2020-04-02 | 2022-09-29 | Sirtsei Pharmaceuticals, Inc. | Compositions and methods for treating age-related diseases and premature aging disorders |
CN114656363A (zh) * | 2022-03-28 | 2022-06-24 | 南京林业大学 | 一种钯催化芳香酯类化合物的合成方法 |
WO2024026443A1 (en) * | 2022-07-28 | 2024-02-01 | Sirtsei Pharmaceuticals, Inc. | Compositions and methods for improving memory and cognition |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
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JPH03255081A (ja) | 1990-03-01 | 1991-11-13 | Mect Corp | dl―グリセオフルビン、dl―グリセオフルビン誘導体およびそれらの中間体の製造方法 |
DE4430910A1 (de) | 1994-08-31 | 1996-03-07 | Eisele Rolf Dipl Ing Fh | Arzneimittel gegen Tinnitus |
JP2008524267A (ja) * | 2004-12-22 | 2008-07-10 | メステックス アクチェンゲゼルシャフト | バニロイド受容体作用薬と神経再生物質阻害物質との混合物、鎮痛薬を生成するためのそれらの使用、および該鎮痛薬を適用する方法 |
EP2008652A1 (de) * | 2007-06-28 | 2008-12-31 | Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts | Griseofulvinanaloge zur Behandlung von Krebs durch Hemmung von zentrosomalem Clustering |
EP2204367A1 (de) | 2008-12-22 | 2010-07-07 | Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts | Griseofulvinanaloge zur Behandlung von Krebs durch Hemmung von zentrosomalem Clustering |
WO2010124695A1 (fr) | 2009-04-26 | 2010-11-04 | Soumia Goutali | Utilisation de la griseofulvine dans l'amelioration des facultes mentales: attention, concentration et memoire |
EP2880023A1 (de) | 2012-08-01 | 2015-06-10 | Pierre Fabre Medicament | Griseofulvinderivate |
CN104860909B (zh) | 2015-04-09 | 2017-03-08 | 西北农林科技大学 | 灰黄霉素衍生物、灰黄霉素及其衍生物的抗菌活性应用 |
WO2017170623A1 (ja) * | 2016-03-30 | 2017-10-05 | 第一三共株式会社 | グリセオフルビン化合物 |
TWI811243B (zh) | 2017-09-29 | 2023-08-11 | 日商第一三共股份有限公司 | 灰黃黴素化合物及醫藥用途 |
-
2018
- 2018-09-26 TW TW107133866A patent/TWI811243B/zh active
- 2018-09-28 JP JP2019545656A patent/JP7102426B2/ja active Active
- 2018-09-28 EP EP18860748.5A patent/EP3689857A4/de active Pending
- 2018-09-28 WO PCT/JP2018/036160 patent/WO2019065928A1/ja unknown
- 2018-09-28 SG SG11202002973WA patent/SG11202002973WA/en unknown
- 2018-09-28 BR BR112020006239-1A patent/BR112020006239A2/pt unknown
- 2018-09-28 AU AU2018342423A patent/AU2018342423B2/en active Active
- 2018-09-28 KR KR1020207011223A patent/KR20200062243A/ko not_active Application Discontinuation
- 2018-09-28 MX MX2020003383A patent/MX2020003383A/es unknown
- 2018-09-28 IL IL273339A patent/IL273339B1/en unknown
- 2018-09-28 CN CN201880069126.0A patent/CN111295378A/zh active Pending
- 2018-09-28 CA CA3076885A patent/CA3076885A1/en active Pending
- 2018-09-28 US US16/648,570 patent/US11407746B2/en active Active
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2020
- 2020-03-27 PH PH12020550168A patent/PH12020550168A1/en unknown
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2022
- 2022-06-21 US US17/845,426 patent/US11993593B2/en active Active
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MX2020003383A (es) | 2020-10-01 |
AU2018342423A1 (en) | 2020-05-21 |
US11993593B2 (en) | 2024-05-28 |
IL273339B1 (en) | 2024-05-01 |
KR20200062243A (ko) | 2020-06-03 |
US20200216433A1 (en) | 2020-07-09 |
EP3689857A4 (de) | 2021-06-09 |
RU2020114910A (ru) | 2021-10-29 |
US11407746B2 (en) | 2022-08-09 |
RU2020114910A3 (de) | 2021-11-24 |
TWI811243B (zh) | 2023-08-11 |
EP3689857A1 (de) | 2020-08-05 |
AU2018342423B2 (en) | 2023-02-23 |
WO2019065928A1 (ja) | 2019-04-04 |
BR112020006239A2 (pt) | 2021-01-26 |
JPWO2019065928A1 (ja) | 2020-10-22 |
US20220411416A1 (en) | 2022-12-29 |
TW201925184A (zh) | 2019-07-01 |
CN111295378A (zh) | 2020-06-16 |
IL273339A (en) | 2020-05-31 |
PH12020550168A1 (en) | 2021-02-22 |
CA3076885A1 (en) | 2019-04-04 |
JP7102426B2 (ja) | 2022-07-19 |
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